Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats

Journal of Lipid Research

Volumn 54, Issue 5, 2013, Pages 1369-1384

  Schober, Gudrun ^a   Arnold, Myrtha ^a   Birtles, Susan ^b   Buckett, Linda K ^b   Pacheco López, Gustavo ^c   Turnbull, Andrew V ^b   Langhans, Wolfgang ^a   Mansouri, Abdelhak ^a  

^a Institute of Food   (Switzerland)

^b ASTRAZENECA   (United Kingdom)

^c Metroipolitan Autonomous University Lerma   (Mexico)

Author keywords

AcylCoA:diacylglycerol acyltransferase 1; Eating; Enterocytes; High fat diet; Ketogenesis; Small intestine; Triacylglycerol

Indexed keywords

3 HYDROXYBUTYRIC ACID; ACYLTRANSFERASE INHIBITOR; AMP ACTIVATED PROTEIN KINASE ALPHA; CARNITINE PALMITOYLTRANSFERASE I; DIACYLGLYCEROL ACYLTRANSFERASE; DIACYLGLYCEROL ACYLTRANSFERASE INIHIBITOR; FATTY ACID; GLYCEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; HYPOCHOLESTEROLEMIC AGENT; PHOSPHORYLATED AMP ACTIVATED PROTEIN KINASE ALPHA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CALORIMETRY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EATING; ENZYME INHIBITION; FATTY ACID BLOOD LEVEL; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; INTESTINE CELL; KETOGENESIS; LIPOLYSIS; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ACYL COENZYME A; ANIMALS; DIACYLGLYCEROL O-ACYLTRANSFERASE; DIET, HIGH-FAT; ELECTRON TRANSPORT COMPLEX III; ENERGY INTAKE; FATTY ACIDS; HUMANS; INTESTINES; LIVER; MALE; OXIDATION-REDUCTION; RATS;

EID: 84876807275     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M035154     Document Type: Article

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