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Volumn 24, Issue 12, 2012, Pages 1505-1516

Vagal Afferents Mediate Early Satiation and Prevent Flavour Avoidance Learning in Response to Intraperitoneally Infused Exendin-4

Author keywords

Avoidance learning; C Fos; Food intake; Meal pattern; Subdiaphragmatic vagal deafferentation

Indexed keywords

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; PROTEIN C FOS;

EID: 84869788004     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2012.02364.x     Document Type: Article
Times cited : (52)

References (59)
  • 2
    • 79960582911 scopus 로고    scopus 로고
    • Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential
    • Torekov SS, Madsbad S, Holst JJ. Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential. Obes Rev 2011; 12: 593-601.
    • (2011) Obes Rev , vol.12 , pp. 593-601
    • Torekov, S.S.1    Madsbad, S.2    Holst, J.J.3
  • 3
    • 19344375318 scopus 로고    scopus 로고
    • Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats
    • Chelikani PK, Haver AC, Reidelberger RD. Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats. Am J Physiol 2005; 288: R1695-R1706.
    • (2005) Am J Physiol , vol.288
    • Chelikani, P.K.1    Haver, A.C.2    Reidelberger, R.D.3
  • 4
    • 34548390977 scopus 로고    scopus 로고
    • The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size
    • Scott KA, Moran TH. The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size. Am J Physiol 2007; 293: R983-R987.
    • (2007) Am J Physiol , vol.293
    • Scott, K.A.1    Moran, T.H.2
  • 5
    • 67649636449 scopus 로고    scopus 로고
    • Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
    • Ruttimann EB, Arnold M, Hillebrand JJ, Geary N, Langhans W. Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms. Endocrinology 2009; 150: 1174-1181.
    • (2009) Endocrinology , vol.150 , pp. 1174-1181
    • Ruttimann, E.B.1    Arnold, M.2    Hillebrand, J.J.3    Geary, N.4    Langhans, W.5
  • 7
    • 80052049014 scopus 로고    scopus 로고
    • GLP-1 and energy balance: an integrated model of short-term and long-term control
    • Barrera JG, Sandoval DA, D'Alessio DA, Seeley RJ. GLP-1 and energy balance: an integrated model of short-term and long-term control. Nat Rev Endocrinol 2011; 7: 507-516.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 507-516
    • Barrera, J.G.1    Sandoval, D.A.2    D'Alessio, D.A.3    Seeley, R.J.4
  • 8
    • 33646512858 scopus 로고    scopus 로고
    • Glucagon and glucagon-like peptide receptors as drug targets
    • Estall JL, Drucker DJ. Glucagon and glucagon-like peptide receptors as drug targets. Curr Pharm Des 2006; 12: 1731-1750.
    • (2006) Curr Pharm Des , vol.12 , pp. 1731-1750
    • Estall, J.L.1    Drucker, D.J.2
  • 9
    • 79959675075 scopus 로고    scopus 로고
    • Comparative effects of the long-acting GLP-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats
    • Hayes MR, Kanoski SE, Alhadeff AL, Grill HJ. Comparative effects of the long-acting GLP-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats. Obesity (Silver Spring) 2011; 19: 1342-1349.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 1342-1349
    • Hayes, M.R.1    Kanoski, S.E.2    Alhadeff, A.L.3    Grill, H.J.4
  • 12
    • 0032966882 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
    • Gutzwiller JP, Drewe J, Goke B, Schmidt H, Rohrer B, Lareida J, Beglinger C. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol 1999; 276: R1541-R1544.
    • (1999) Am J Physiol , vol.276
    • Gutzwiller, J.P.1    Drewe, J.2    Goke, B.3    Schmidt, H.4    Rohrer, B.5    Lareida, J.6    Beglinger, C.7
  • 13
    • 79960741385 scopus 로고    scopus 로고
    • Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4
    • Kanoski SE, Fortin SM, Arnold M, Grill HJ, Hayes MR. Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4. Endocrinology 2011; 152: 3103-3112.
    • (2011) Endocrinology , vol.152 , pp. 3103-3112
    • Kanoski, S.E.1    Fortin, S.M.2    Arnold, M.3    Grill, H.J.4    Hayes, M.R.5
  • 14
    • 80053631384 scopus 로고    scopus 로고
    • Brain activation following peripheral administration of the GLP-1 receptor agonist exendin-4
    • Baraboi ED, St-Pierre DH, Shooner J, Timofeeva E, Richard D. Brain activation following peripheral administration of the GLP-1 receptor agonist exendin-4. Am J Physiol 2011; 301: R1011-R1024.
    • (2011) Am J Physiol , vol.301
    • Baraboi, E.D.1    St-Pierre, D.H.2    Shooner, J.3    Timofeeva, E.4    Richard, D.5
  • 15
    • 77953915094 scopus 로고    scopus 로고
    • Exenatide reduces food intake and activates the enteric nervous system of the gastrointestinal tract and the dorsal vagal complex of the hindbrain in the rat by a GLP-1 receptor
    • Washington MC, Raboin SJ, Thompson W, Larsen CJ, Sayegh AI. Exenatide reduces food intake and activates the enteric nervous system of the gastrointestinal tract and the dorsal vagal complex of the hindbrain in the rat by a GLP-1 receptor. Brain Res 2010; 1344: 124-133.
    • (2010) Brain Res , vol.1344 , pp. 124-133
    • Washington, M.C.1    Raboin, S.J.2    Thompson, W.3    Larsen, C.J.4    Sayegh, A.I.5
  • 16
    • 23844554610 scopus 로고    scopus 로고
    • Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice
    • Talsania T, Anini Y, Siu S, Drucker DJ, Brubaker PL. Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology 2005; 146: 3748-3756.
    • (2005) Endocrinology , vol.146 , pp. 3748-3756
    • Talsania, T.1    Anini, Y.2    Siu, S.3    Drucker, D.J.4    Brubaker, P.L.5
  • 19
    • 63849248275 scopus 로고    scopus 로고
    • Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety
    • Williams DL, Baskin DG, Schwartz MW. Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. Endocrinology 2009; 150: 1680-1687.
    • (2009) Endocrinology , vol.150 , pp. 1680-1687
    • Williams, D.L.1    Baskin, D.G.2    Schwartz, M.W.3
  • 21
    • 48849100361 scopus 로고    scopus 로고
    • The vagus nerve, food intake and obesity
    • Berthoud HR. The vagus nerve, food intake and obesity. Regul Pept 2008; 149: 15-25.
    • (2008) Regul Pept , vol.149 , pp. 15-25
    • Berthoud, H.R.1
  • 22
    • 84858797843 scopus 로고    scopus 로고
    • Exenatide and feeding: possible peripheral neuronal pathways
    • Hunt JV, Washington MC, Sayegh AI. Exenatide and feeding: possible peripheral neuronal pathways. Peptides 2012; 33: 285-290.
    • (2012) Peptides , vol.33 , pp. 285-290
    • Hunt, J.V.1    Washington, M.C.2    Sayegh, A.I.3
  • 23
    • 34447267513 scopus 로고    scopus 로고
    • Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis
    • Amori RE, Lau J, Pittas AG. Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. JAMA 2007; 298: 194-206.
    • (2007) JAMA , vol.298 , pp. 194-206
    • Amori, R.E.1    Lau, J.2    Pittas, A.G.3
  • 24
    • 84857045922 scopus 로고    scopus 로고
    • The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
    • Kanoski SE, Rupprecht LE, Fortin SM, De Jonghe BC, Hayes MR. The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide. Neuropharmacology 2012; 62: 1916-1927.
    • (2012) Neuropharmacology , vol.62 , pp. 1916-1927
    • Kanoski, S.E.1    Rupprecht, L.E.2    Fortin, S.M.3    De Jonghe, B.C.4    Hayes, M.R.5
  • 25
    • 0028019633 scopus 로고
    • A method for selective section of vagal afferent or efferent axons in the rat
    • Norgren R, Smith GP. A method for selective section of vagal afferent or efferent axons in the rat. Am J Physiol 1994; 267: R1136-R1141.
    • (1994) Am J Physiol , vol.267
    • Norgren, R.1    Smith, G.P.2
  • 26
    • 33751120393 scopus 로고    scopus 로고
    • Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat
    • Arnold M, Mura A, Langhans W, Geary N. Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat. J Neurosci 2006; 26: 11052-11060.
    • (2006) J Neurosci , vol.26 , pp. 11052-11060
    • Arnold, M.1    Mura, A.2    Langhans, W.3    Geary, N.4
  • 27
    • 0022149006 scopus 로고
    • Afferent axons in abdominal vagus mediate satiety effect of cholecystoskinin in rats
    • Smith GP, Jerome C, Norgren R. Afferent axons in abdominal vagus mediate satiety effect of cholecystoskinin in rats. Am J Physiol 1985; 249: R638-R641.
    • (1985) Am J Physiol , vol.249
    • Smith, G.P.1    Jerome, C.2    Norgren, R.3
  • 28
    • 43249084826 scopus 로고    scopus 로고
    • Conditioned flavor preferences: evaluating postingestive reinforcement by nutrients
    • Ackroff K, Sclafani A. Conditioned flavor preferences: evaluating postingestive reinforcement by nutrients. Curr Protoc Neurosci 2001; Chapter 8: Unit 8.6F.
    • (2001) Curr Protoc Neurosci , vol.8
    • Ackroff, K.1    Sclafani, A.2
  • 29
    • 35148838131 scopus 로고    scopus 로고
    • Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride
    • Rinaman L, Dzmura V. Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride. Am J Physiol 2007; 293: R1495-R1503.
    • (2007) Am J Physiol , vol.293
    • Rinaman, L.1    Dzmura, V.2
  • 32
    • 66649088029 scopus 로고    scopus 로고
    • Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    • Hayes MR, Bradley L, Grill HJ. Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling. Endocrinology 2009; 150: 2654-2659.
    • (2009) Endocrinology , vol.150 , pp. 2654-2659
    • Hayes, M.R.1    Bradley, L.2    Grill, H.J.3
  • 33
    • 84870970760 scopus 로고    scopus 로고
    • Missing values, outliers, robust statistics & non-parameteric methods. LG-GC Europe Online Supplement
    • Burke S. Missing values, outliers, robust statistics & non-parameteric methods. LG-GC Europe Online Supplement http://www.lcgceurope.com/lcgceurope/data/articlestandard/lcgceurope/502001/4509/article.pdf.
    • Burke, S.1
  • 34
    • 0022690482 scopus 로고
    • Specific postoperative syndromes after total and selective vagotomies in the rat
    • Kraly FS, Jerome C, Smith GP. Specific postoperative syndromes after total and selective vagotomies in the rat. Appetite 1986; 7: 1-17.
    • (1986) Appetite , vol.7 , pp. 1-17
    • Kraly, F.S.1    Jerome, C.2    Smith, G.P.3
  • 35
    • 82755164888 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonists suppress water intake independent of effects on food intake
    • McKay NJ, Kanoski SE, Hayes MR, Daniels D. Glucagon-like peptide-1 receptor agonists suppress water intake independent of effects on food intake. Am J Physiol 2011; 301: R1755-R1764.
    • (2011) Am J Physiol , vol.301
    • McKay, N.J.1    Kanoski, S.E.2    Hayes, M.R.3    Daniels, D.4
  • 36
    • 58149484806 scopus 로고    scopus 로고
    • Loss of cholecystokinin and glucagon-like peptide-1-induced satiation in mice lacking serotonin 2C receptors
    • Asarian L. Loss of cholecystokinin and glucagon-like peptide-1-induced satiation in mice lacking serotonin 2C receptors. Am J Physiol 2009; 296: R51-R56.
    • (2009) Am J Physiol , vol.296
    • Asarian, L.1
  • 37
    • 84855314566 scopus 로고    scopus 로고
    • Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms
    • Zhang J, Ritter RC. Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms. Am J Physiol 2012; 302: R264-R273.
    • (2012) Am J Physiol , vol.302
    • Zhang, J.1    Ritter, R.C.2
  • 38
    • 0036627597 scopus 로고    scopus 로고
    • Multiple neural systems controlling food intake and body weight
    • Berthoud HR. Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 2002; 26: 393-428.
    • (2002) Neurosci Biobehav Rev , vol.26 , pp. 393-428
    • Berthoud, H.R.1
  • 39
    • 47949104953 scopus 로고    scopus 로고
    • Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation
    • Hayes MR, Skibicka KP, Grill HJ. Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation. Endocrinology 2008; 149: 4059-4068.
    • (2008) Endocrinology , vol.149 , pp. 4059-4068
    • Hayes, M.R.1    Skibicka, K.P.2    Grill, H.J.3
  • 40
    • 0000880346 scopus 로고    scopus 로고
    • C-fos expression as a marker of functional activity in the brain
    • Boulton AA, Baker GB, Bateson AN, eds. Neuromethods, Cell Neurobiology Techniques. Totowa (New Jersey): Humana Press
    • Krukoff TL. C-fos expression as a marker of functional activity in the brain. In: Boulton AA, Baker GB, Bateson AN, eds. Neuromethods, Cell Neurobiology Techniques. Totowa (New Jersey): Humana Press 1999; 33: 213-230.
    • (1999) , vol.33 , pp. 213-230
    • Krukoff, T.L.1
  • 42
    • 0036896243 scopus 로고    scopus 로고
    • The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness
    • Kinzig KP, D'Alessio DA, Seeley RJ. The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. J Neurosci 2002; 22: 10470-10476.
    • (2002) J Neurosci , vol.22 , pp. 10470-10476
    • Kinzig, K.P.1    D'Alessio, D.A.2    Seeley, R.J.3
  • 43
    • 0032756657 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (7-36) amide: a central regulator of satiety and interoceptive stress
    • van Dijk G, Thiele TE. Glucagon-like peptide-1 (7-36) amide: a central regulator of satiety and interoceptive stress. Neuropeptides 1999; 33: 406-414.
    • (1999) Neuropeptides , vol.33 , pp. 406-414
    • van Dijk, G.1    Thiele, T.E.2
  • 44
    • 0031891391 scopus 로고    scopus 로고
    • PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats
    • McMahon LR, Wellman PJ. PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats. Am J Physiol 1998; 274: R23-R29.
    • (1998) Am J Physiol , vol.274
    • McMahon, L.R.1    Wellman, P.J.2
  • 45
    • 84856102513 scopus 로고    scopus 로고
    • GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake
    • Alhadeff AL, Rupprecht LE, Hayes MR. GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake. Endocrinology 2012; 153: 647-658.
    • (2012) Endocrinology , vol.153 , pp. 647-658
    • Alhadeff, A.L.1    Rupprecht, L.E.2    Hayes, M.R.3
  • 46
    • 79960645242 scopus 로고    scopus 로고
    • Gut feelings: the emerging biology of gut-brain communication
    • Mayer EA. Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci 2011; 12: 453-466.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 453-466
    • Mayer, E.A.1
  • 48
    • 0036051108 scopus 로고    scopus 로고
    • Subdiaphragmatic vagal afferent innervation in activation of an opioidergic antinociceptive system in response to colorectal distension in rats
    • Gschossmann JM, Mayer EA, Miller JC, Raybould HE. Subdiaphragmatic vagal afferent innervation in activation of an opioidergic antinociceptive system in response to colorectal distension in rats. Neurogastroenterol Motil 2002; 14: 403-408.
    • (2002) Neurogastroenterol Motil , vol.14 , pp. 403-408
    • Gschossmann, J.M.1    Mayer, E.A.2    Miller, J.C.3    Raybould, H.E.4
  • 50
    • 0032504654 scopus 로고    scopus 로고
    • Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem
    • Thiele TE, Seeley RJ, D'Alessio D, Eng J, Bernstein IL, Woods SC, van Dijk G. Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem. Brain Res 1998; 801: 164-170.
    • (1998) Brain Res , vol.801 , pp. 164-170
    • Thiele, T.E.1    Seeley, R.J.2    D'Alessio, D.3    Eng, J.4    Bernstein, I.L.5    Woods, S.C.6    van Dijk, G.7
  • 51
    • 70049113965 scopus 로고    scopus 로고
    • Immune challenge and satiety-related activation of both distinct and overlapping neuronal populations in the brainstem indicate parallel pathways for viscerosensory signaling
    • Gaykema RP, Daniels TE, Shapiro NJ, Thacker GC, Park SM, Goehler LE. Immune challenge and satiety-related activation of both distinct and overlapping neuronal populations in the brainstem indicate parallel pathways for viscerosensory signaling. Brain Res 2009; 1294: 61-79.
    • (2009) Brain Res , vol.1294 , pp. 61-79
    • Gaykema, R.P.1    Daniels, T.E.2    Shapiro, N.J.3    Thacker, G.C.4    Park, S.M.5    Goehler, L.E.6
  • 52
    • 0242694943 scopus 로고    scopus 로고
    • Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation
    • Rinaman L. Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation. J Neurosci 2003; 23: 10084-10092.
    • (2003) J Neurosci , vol.23 , pp. 10084-10092
    • Rinaman, L.1
  • 53
    • 0023765925 scopus 로고
    • Role of the area postrema in three putative measures of motion sickness in the rat
    • Sutton RL, Fox RA, Daunton NG. Role of the area postrema in three putative measures of motion sickness in the rat. Behav Neural Biol 1988; 50: 133-152.
    • (1988) Behav Neural Biol , vol.50 , pp. 133-152
    • Sutton, R.L.1    Fox, R.A.2    Daunton, N.G.3
  • 54
    • 0038706177 scopus 로고    scopus 로고
    • The amygdalar circuit that acquires taste aversion memory differs from the circuit that extinguishes it
    • Bahar A, Samuel A, Hazvi S, Dudai Y. The amygdalar circuit that acquires taste aversion memory differs from the circuit that extinguishes it. Eur J Neurosci 2003; 17: 1527-1530.
    • (2003) Eur J Neurosci , vol.17 , pp. 1527-1530
    • Bahar, A.1    Samuel, A.2    Hazvi, S.3    Dudai, Y.4
  • 56
    • 0036307872 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
    • Yamamoto H. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. J Clin Invest 2002; 110: 43-52.
    • (2002) J Clin Invest , vol.110 , pp. 43-52
    • Yamamoto, H.1
  • 57
    • 77954102250 scopus 로고    scopus 로고
    • Hepatic-portal vein infusions of glucagon-like peptide-1 reduce meal size and increase c-Fos expression in the nucleus tractus solitarii, area postrema and central nucleus of the amygdala in rats
    • Baumgartner I, Pacheco-Lopez G, Ruttimann EB, Arnold M, Asarian L, Langhans W, Geary N, Hillebrand JJ. Hepatic-portal vein infusions of glucagon-like peptide-1 reduce meal size and increase c-Fos expression in the nucleus tractus solitarii, area postrema and central nucleus of the amygdala in rats. J Neuroendocrinol 2010; 22: 557-563.
    • (2010) J Neuroendocrinol , vol.22 , pp. 557-563
    • Baumgartner, I.1    Pacheco-Lopez, G.2    Ruttimann, E.B.3    Arnold, M.4    Asarian, L.5    Langhans, W.6    Geary, N.7    Hillebrand, J.J.8
  • 58
    • 80054035293 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake
    • Dossat AM, Lilly N, Kay K, Williams DL. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. J Neurosci 2011; 31: 14453-14457.
    • (2011) J Neurosci , vol.31 , pp. 14453-14457
    • Dossat, A.M.1    Lilly, N.2    Kay, K.3    Williams, D.L.4
  • 59
    • 84859360922 scopus 로고    scopus 로고
    • The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors
    • Dickson SL, Shirazi RH, Caroline HC, Bergquist F, Nissbrandt H, Skibicka KP. The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors. J Neurosci 2012; 32: 4812-4820.
    • (2012) J Neurosci , vol.32 , pp. 4812-4820
    • Dickson, S.L.1    Shirazi, R.H.2    Caroline, H.C.3    Bergquist, F.4    Nissbrandt, H.5    Skibicka, K.P.6


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