메뉴 건너뛰기




Volumn 8, Issue 1, 2013, Pages

The microtubule stabilizer patupilone counteracts ionizing radiation-induced matrix metalloproteinase activity and tumor cell invasion

Author keywords

Ionizing radiation; Matrix metalloproteinase; Microtubule stabilizing agent; Patupilone; Tissue inhibitor of metalloproteinases

Indexed keywords

ANTIBODY; CELL EXTRACT; EPOTHILONE B; MATRIX METALLOPROTEINASE; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

EID: 84876806829     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-8-105     Document Type: Article
Times cited : (11)

References (54)
  • 1
    • 0033950286 scopus 로고    scopus 로고
    • Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: results of an Eastern Cooperative Oncology Group trial
    • Bonomi P, Kim K, Fairclough D, Cella D, Kugler J, Rowinsky E, Jiroutek M, Johnson D. Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: results of an Eastern Cooperative Oncology Group trial. J Clin Oncol 2000, 18:623-631.
    • (2000) J Clin Oncol , vol.18 , pp. 623-631
    • Bonomi, P.1    Kim, K.2    Fairclough, D.3    Cella, D.4    Kugler, J.5    Rowinsky, E.6    Jiroutek, M.7    Johnson, D.8
  • 5
    • 1542380040 scopus 로고    scopus 로고
    • Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization, and cytotoxicity
    • Buey RM, Diaz JF, Andreu JM, O'Brate A, Giannakakou P, Nicolaou KC, Sasmal PK, Ritzen A, Namoto K. Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization, and cytotoxicity. Chem Biol 2004, 11:225-236.
    • (2004) Chem Biol , vol.11 , pp. 225-236
    • Buey, R.M.1    Diaz, J.F.2    Andreu, J.M.3    O'Brate, A.4    Giannakakou, P.5    Nicolaou, K.C.6    Sasmal, P.K.7    Ritzen, A.8    Namoto, K.9
  • 6
    • 64049097460 scopus 로고    scopus 로고
    • Microtubule dynamics as a target in oncology
    • 10.1016/j.ctrv.2008.11.001, 2778221, 19117686
    • Risinger AL, Giles FJ, Mooberry SL. Microtubule dynamics as a target in oncology. Cancer Treat Rev 2009, 35:255-261. 10.1016/j.ctrv.2008.11.001, 2778221, 19117686.
    • (2009) Cancer Treat Rev , vol.35 , pp. 255-261
    • Risinger, A.L.1    Giles, F.J.2    Mooberry, S.L.3
  • 7
    • 60849108366 scopus 로고    scopus 로고
    • Integrating epothilones into the treatment of patients with metastatic breast cancer: clinical perspectives on incorporating recent data in the practice setting
    • Cigler T, Vahdat L. Integrating epothilones into the treatment of patients with metastatic breast cancer: clinical perspectives on incorporating recent data in the practice setting. Clin Breast Cancer 2008, 8(Suppl 4):S166-S170.
    • (2008) Clin Breast Cancer , vol.8 , Issue.SUPPL. 4
    • Cigler, T.1    Vahdat, L.2
  • 8
    • 77953561380 scopus 로고    scopus 로고
    • Phase I trial using patupilone (epothilone B) and concurrent radiotherapy for central nervous system malignancies
    • 10.1016/j.ijrobp.2009.06.050, 19879067
    • Fogh S, Machtay M, Werner-Wasik M, Curran WJ, Bonanni R, Axelrod R, Andrews D, Dicker AP. Phase I trial using patupilone (epothilone B) and concurrent radiotherapy for central nervous system malignancies. Int J Radiat Oncol Biol Phys 2010, 77:1009-1016. 10.1016/j.ijrobp.2009.06.050, 19879067.
    • (2010) Int J Radiat Oncol Biol Phys , vol.77 , pp. 1009-1016
    • Fogh, S.1    Machtay, M.2    Werner-Wasik, M.3    Curran, W.J.4    Bonanni, R.5    Axelrod, R.6    Andrews, D.7    Dicker, A.P.8
  • 10
    • 33644831567 scopus 로고    scopus 로고
    • Phase I dose-finding study of weekly single-agent patupilone in patients with advanced solid tumors
    • 10.1200/JCO.2005.03.0981, 16301595
    • Rubin EH, Rothermel J, Tesfaye F, Chen T, Hubert M, Ho YY, Hsu CH, Oza AM. Phase I dose-finding study of weekly single-agent patupilone in patients with advanced solid tumors. J Clin Oncol 2005, 23:9120-9129. 10.1200/JCO.2005.03.0981, 16301595.
    • (2005) J Clin Oncol , vol.23 , pp. 9120-9129
    • Rubin, E.H.1    Rothermel, J.2    Tesfaye, F.3    Chen, T.4    Hubert, M.5    Ho, Y.Y.6    Hsu, C.H.7    Oza, A.M.8
  • 11
    • 84861994651 scopus 로고    scopus 로고
    • Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of a single-institution phase I/II trial
    • 10.1159/000339152, 22688083
    • Oehler C, Frei K, Rushing EJ, McSheehy PM, Weber D, Allegrini PR, Weniger D, Lutolf UM, Knuth A, Yonekawa Y, et al. Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of a single-institution phase I/II trial. Oncology 2012, 83:1-9. 10.1159/000339152, 22688083.
    • (2012) Oncology , vol.83 , pp. 1-9
    • Oehler, C.1    Frei, K.2    Rushing, E.J.3    McSheehy, P.M.4    Weber, D.5    Allegrini, P.R.6    Weniger, D.7    Lutolf, U.M.8    Knuth, A.9    Yonekawa, Y.10
  • 12
    • 84855568443 scopus 로고    scopus 로고
    • Ixabepilone for the treatment of breast cancer
    • 10.3109/07853890.2011.579151, 21585248
    • Alvarez RH, Valero V, Hortobagyi GN. Ixabepilone for the treatment of breast cancer. Ann Med 2011, 43:477-486. 10.3109/07853890.2011.579151, 21585248.
    • (2011) Ann Med , vol.43 , pp. 477-486
    • Alvarez, R.H.1    Valero, V.2    Hortobagyi, G.N.3
  • 13
    • 79955810347 scopus 로고    scopus 로고
    • Global experience with ixabepilone in breast cancer
    • 10.1586/era.11.41, 21554041
    • Kaklamani VG, Xu BH, Gomez HL. Global experience with ixabepilone in breast cancer. Expert Rev Anticancer Ther 2011, 11:683-692. 10.1586/era.11.41, 21554041.
    • (2011) Expert Rev Anticancer Ther , vol.11 , pp. 683-692
    • Kaklamani, V.G.1    Xu, B.H.2    Gomez, H.L.3
  • 14
    • 63149182838 scopus 로고    scopus 로고
    • Role of the microenvironment for radiosensitization by patupilone
    • 10.1158/1078-0432.CCR-08-0969, 19228735
    • Bley CR, Jochum W, Orlowski K, Furmanova P, Vuong V, McSheehy PM, Pruschy M. Role of the microenvironment for radiosensitization by patupilone. Clin Cancer Res 2009, 15:1335-1342. 10.1158/1078-0432.CCR-08-0969, 19228735.
    • (2009) Clin Cancer Res , vol.15 , pp. 1335-1342
    • Bley, C.R.1    Jochum, W.2    Orlowski, K.3    Furmanova, P.4    Vuong, V.5    McSheehy, P.M.6    Pruschy, M.7
  • 17
    • 33749565180 scopus 로고    scopus 로고
    • Microtubule-targeting agents inhibit angiogenesis at subtoxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton
    • 10.1158/1535-7163.MCT-06-0242, 16985069
    • Bijman MN, van Nieuw Amerongen GP, Laurens N, van Hinsbergh VW, Boven E. Microtubule-targeting agents inhibit angiogenesis at subtoxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton. Mol Cancer Ther 2006, 5:2348-2357. 10.1158/1535-7163.MCT-06-0242, 16985069.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2348-2357
    • Bijman, M.N.1    van Nieuw Amerongen, G.P.2    Laurens, N.3    van Hinsbergh, V.W.4    Boven, E.5
  • 18
    • 27744607653 scopus 로고    scopus 로고
    • Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure
    • 10.1158/1078-0432.CCR-05-1165, 16278399
    • Ferretti S, Allegrini PR, O'Reilly T, Schnell C, Stumm M, Wartmann M, Wood J, McSheehy PM. Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure. Clin Cancer Res 2005, 11:7773-7784. 10.1158/1078-0432.CCR-05-1165, 16278399.
    • (2005) Clin Cancer Res , vol.11 , pp. 7773-7784
    • Ferretti, S.1    Allegrini, P.R.2    O'Reilly, T.3    Schnell, C.4    Stumm, M.5    Wartmann, M.6    Wood, J.7    McSheehy, P.M.8
  • 19
    • 79960342262 scopus 로고    scopus 로고
    • Regulation of VEGF-expression by patupilone and ionizing radiation in lung adenocarcinoma cells
    • 10.1016/j.lungcan.2011.01.010, 21333376
    • Rohrer Bley C, Orlowski K, Furmanova P, McSheehy PM, Pruschy M. Regulation of VEGF-expression by patupilone and ionizing radiation in lung adenocarcinoma cells. Lung Cancer 2011, 73:294-301. 10.1016/j.lungcan.2011.01.010, 21333376.
    • (2011) Lung Cancer , vol.73 , pp. 294-301
    • Rohrer Bley, C.1    Orlowski, K.2    Furmanova, P.3    McSheehy, P.M.4    Pruschy, M.5
  • 20
    • 56249114089 scopus 로고    scopus 로고
    • Vesicular trafficking and secretion of matrix metalloproteinases-2, -9 and tissue inhibitor of metalloproteinases-1 in neuronal cells
    • 10.1016/j.mcn.2008.08.004, 18817873
    • Sbai O, Ferhat L, Bernard A, Gueye Y, Ould-Yahoui A, Thiolloy S, Charrat E, Charton G, Tremblay E, Risso JJ, et al. Vesicular trafficking and secretion of matrix metalloproteinases-2, -9 and tissue inhibitor of metalloproteinases-1 in neuronal cells. Mol Cell Neurosci 2008, 39:549-568. 10.1016/j.mcn.2008.08.004, 18817873.
    • (2008) Mol Cell Neurosci , vol.39 , pp. 549-568
    • Sbai, O.1    Ferhat, L.2    Bernard, A.3    Gueye, Y.4    Ould-Yahoui, A.5    Thiolloy, S.6    Charrat, E.7    Charton, G.8    Tremblay, E.9    Risso, J.J.10
  • 21
    • 10844266658 scopus 로고    scopus 로고
    • Microtubule-dependent matrix metalloproteinase-2/matrix metalloproteinase-9 exocytosis: prerequisite in human melanoma cell invasion
    • 10.1158/0008-5472.CAN-04-0324, 15604254
    • Schnaeker EM, Ossig R, Ludwig T, Dreier R, Oberleithner H, Wilhelmi M, Schneider SW. Microtubule-dependent matrix metalloproteinase-2/matrix metalloproteinase-9 exocytosis: prerequisite in human melanoma cell invasion. Cancer Res 2004, 64:8924-8931. 10.1158/0008-5472.CAN-04-0324, 15604254.
    • (2004) Cancer Res , vol.64 , pp. 8924-8931
    • Schnaeker, E.M.1    Ossig, R.2    Ludwig, T.3    Dreier, R.4    Oberleithner, H.5    Wilhelmi, M.6    Schneider, S.W.7
  • 22
    • 0026740325 scopus 로고
    • Taxol blocks processes essential for prostate tumor cell (PC-3 ML) invasion and metastases
    • Stearns ME, Wang M. Taxol blocks processes essential for prostate tumor cell (PC-3 ML) invasion and metastases. Cancer Res 1992, 52:3776-3781.
    • (1992) Cancer Res , vol.52 , pp. 3776-3781
    • Stearns, M.E.1    Wang, M.2
  • 23
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • 10.1038/nrc745, 11990853
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002, 2:161-174. 10.1038/nrc745, 11990853.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 24
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: regulators of the tumor microenvironment
    • 10.1016/j.cell.2010.03.015, 2862057, 20371345
    • Kessenbrock K, Plaks V, Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010, 141:52-67. 10.1016/j.cell.2010.03.015, 2862057, 20371345.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 25
    • 45849098735 scopus 로고    scopus 로고
    • The role of tissue inhibitors of metalloproteinases in tumorigenesis and metastasis
    • 10.1080/10408360801973244, 18568853
    • Cruz-Munoz W, Khokha R. The role of tissue inhibitors of metalloproteinases in tumorigenesis and metastasis. Crit Rev Clin Lab Sci 2008, 45:291-338. 10.1080/10408360801973244, 18568853.
    • (2008) Crit Rev Clin Lab Sci , vol.45 , pp. 291-338
    • Cruz-Munoz, W.1    Khokha, R.2
  • 26
    • 0030592783 scopus 로고    scopus 로고
    • The recombinant catalytic domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) induces activation of progelatinase A and progelatinase A complexed with TIMP-2
    • 10.1016/S0014-5793(96)01206-9, 8955363
    • Lichte A, Kolkenbrock H, Tschesche H. The recombinant catalytic domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) induces activation of progelatinase A and progelatinase A complexed with TIMP-2. FEBS Lett 1996, 397:277-282. 10.1016/S0014-5793(96)01206-9, 8955363.
    • (1996) FEBS Lett , vol.397 , pp. 277-282
    • Lichte, A.1    Kolkenbrock, H.2    Tschesche, H.3
  • 27
    • 2442475518 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-2 growth-stimulatory activity is mediated by nuclear factor-kappa B in A549 lung epithelial cells
    • 10.1016/j.biocel.2004.02.004, 15147743
    • Lizarraga F, Maldonado V, Melendez-Zajgla J. Tissue inhibitor of metalloproteinases-2 growth-stimulatory activity is mediated by nuclear factor-kappa B in A549 lung epithelial cells. Int J Biochem Cell Biol 2004, 36:1655-1663. 10.1016/j.biocel.2004.02.004, 15147743.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1655-1663
    • Lizarraga, F.1    Maldonado, V.2    Melendez-Zajgla, J.3
  • 28
    • 0032529290 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase (TIMP)-1 induces differentiation and an antiapoptotic phenotype in germinal center B cells
    • Guedez L, Courtemanch L, Stetler-Stevenson M. Tissue inhibitor of metalloproteinase (TIMP)-1 induces differentiation and an antiapoptotic phenotype in germinal center B cells. Blood 1998, 92:1342-1349.
    • (1998) Blood , vol.92 , pp. 1342-1349
    • Guedez, L.1    Courtemanch, L.2    Stetler-Stevenson, M.3
  • 30
    • 41849140534 scopus 로고    scopus 로고
    • Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts
    • 10.1002/pros.20702, 18247403
    • Agemy L, Harmelin A, Waks T, Leibovitch I, Rabin T, Pfeffer MR, Eshhar Z. Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts. Prostate 2008, 68:530-539. 10.1002/pros.20702, 18247403.
    • (2008) Prostate , vol.68 , pp. 530-539
    • Agemy, L.1    Harmelin, A.2    Waks, T.3    Leibovitch, I.4    Rabin, T.5    Pfeffer, M.R.6    Eshhar, Z.7
  • 32
    • 0037710384 scopus 로고    scopus 로고
    • Increased plasma levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in lung and breast cancer are altered during chest radiotherapy
    • 10.1016/S0360-3016(03)00161-5, 12829155
    • Susskind H, Hymowitz MH, Lau YH, Atkins HL, Hurewitz AN, Valentine ES, Meek AG, Zucker S. Increased plasma levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in lung and breast cancer are altered during chest radiotherapy. Int J Radiat Oncol Biol Phys 2003, 56:1161-1169. 10.1016/S0360-3016(03)00161-5, 12829155.
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 1161-1169
    • Susskind, H.1    Hymowitz, M.H.2    Lau, Y.H.3    Atkins, H.L.4    Hurewitz, A.N.5    Valentine, E.S.6    Meek, A.G.7    Zucker, S.8
  • 33
    • 37249057731 scopus 로고    scopus 로고
    • Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis
    • 10.1074/jbc.M705993200, 17895241
    • Partridge JJ, Madsen MA, Ardi VC, Papagiannakopoulos T, Kupriyanova TA, Quigley JP, Deryugina EI. Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis. J Biol Chem 2007, 282:35964-35977. 10.1074/jbc.M705993200, 17895241.
    • (2007) J Biol Chem , vol.282 , pp. 35964-35977
    • Partridge, J.J.1    Madsen, M.A.2    Ardi, V.C.3    Papagiannakopoulos, T.4    Kupriyanova, T.A.5    Quigley, J.P.6    Deryugina, E.I.7
  • 35
    • 76749161464 scopus 로고    scopus 로고
    • Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation
    • 10.1002/pmic.200900162, 19957288
    • Broggini-Tenzer A, Hollenstein A, Pianowski Z, Wampfler A, Furmanova P, Winssinger N, Pruschy M. Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation. Proteomics 2010, 10:304-314. 10.1002/pmic.200900162, 19957288.
    • (2010) Proteomics , vol.10 , pp. 304-314
    • Broggini-Tenzer, A.1    Hollenstein, A.2    Pianowski, Z.3    Wampfler, A.4    Furmanova, P.5    Winssinger, N.6    Pruschy, M.7
  • 36
    • 4644312036 scopus 로고    scopus 로고
    • Matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 production in human gingival fibroblasts: the role of protein kinase C
    • 10.1111/j.1600-0765.2004.00745.x, 15324351
    • Domeij H, Modeer T, Yucel-Lindberg T. Matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 production in human gingival fibroblasts: the role of protein kinase C. J Periodontal Res 2004, 39:308-314. 10.1111/j.1600-0765.2004.00745.x, 15324351.
    • (2004) J Periodontal Res , vol.39 , pp. 308-314
    • Domeij, H.1    Modeer, T.2    Yucel-Lindberg, T.3
  • 37
    • 0034284266 scopus 로고    scopus 로고
    • Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells
    • 10.1016/S0304-3940(00)01358-6, 10963898
    • Park MJ, Park IC, Hur JH, Rhee CH, Choe TB, Yi DH, Hong SI, Lee SH. Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells. Neurosci Lett 2000, 290:201-204. 10.1016/S0304-3940(00)01358-6, 10963898.
    • (2000) Neurosci Lett , vol.290 , pp. 201-204
    • Park, M.J.1    Park, I.C.2    Hur, J.H.3    Rhee, C.H.4    Choe, T.B.5    Yi, D.H.6    Hong, S.I.7    Lee, S.H.8
  • 38
    • 0142212329 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinases: an overview
    • 10.1023/A:1026028303196, 14619979
    • Chakraborti S, Mandal M, Das S, Mandal A, Chakraborti T. Regulation of matrix metalloproteinases: an overview. Mol Cell Biochem 2003, 253:269-285. 10.1023/A:1026028303196, 14619979.
    • (2003) Mol Cell Biochem , vol.253 , pp. 269-285
    • Chakraborti, S.1    Mandal, M.2    Das, S.3    Mandal, A.4    Chakraborti, T.5
  • 39
    • 0029774746 scopus 로고    scopus 로고
    • APMA (4-aminophenylmercuric acetate) activation of stromelysin-1 involves protein interactions in addition to those with cysteine-75 in the propeptide
    • 10.1021/bi960618e, 8780527
    • Galazka G, Windsor LJ, Birkedal-Hansen H, Engler JA. APMA (4-aminophenylmercuric acetate) activation of stromelysin-1 involves protein interactions in addition to those with cysteine-75 in the propeptide. Biochemistry 1996, 35:11221-11227. 10.1021/bi960618e, 8780527.
    • (1996) Biochemistry , vol.35 , pp. 11221-11227
    • Galazka, G.1    Windsor, L.J.2    Birkedal-Hansen, H.3    Engler, J.A.4
  • 40
    • 28044461236 scopus 로고    scopus 로고
    • Angiogenesis and tumor growth inhibition by a matrix metalloproteinase inhibitor targeting radiation-induced invasion
    • 10.1158/1535-7163.MCT-05-0179, 16275993
    • Kaliski A, Maggiorella L, Cengel KA, Mathe D, Rouffiac V, Opolon P, Lassau N, Bourhis J, Deutsch E. Angiogenesis and tumor growth inhibition by a matrix metalloproteinase inhibitor targeting radiation-induced invasion. Mol Cancer Ther 2005, 4:1717-1728. 10.1158/1535-7163.MCT-05-0179, 16275993.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1717-1728
    • Kaliski, A.1    Maggiorella, L.2    Cengel, K.A.3    Mathe, D.4    Rouffiac, V.5    Opolon, P.6    Lassau, N.7    Bourhis, J.8    Deutsch, E.9
  • 41
    • 26644457881 scopus 로고    scopus 로고
    • Patupilone (epothilone B, EPO906) inhibits growth and metastasis of experimental prostate tumors in vivo
    • 10.1002/pros.20289, 15948135
    • O'Reilly T, McSheehy PM, Wenger F, Hattenberger M, Muller M, Vaxelaire J, Altmann KH, Wartmann M. Patupilone (epothilone B, EPO906) inhibits growth and metastasis of experimental prostate tumors in vivo. Prostate 2005, 65:231-240. 10.1002/pros.20289, 15948135.
    • (2005) Prostate , vol.65 , pp. 231-240
    • O'Reilly, T.1    McSheehy, P.M.2    Wenger, F.3    Hattenberger, M.4    Muller, M.5    Vaxelaire, J.6    Altmann, K.H.7    Wartmann, M.8
  • 42
    • 51849114328 scopus 로고    scopus 로고
    • Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo
    • 10.1007/s00280-008-0695-9, 18301895
    • O'Reilly T, Wartmann M, Brueggen J, Allegrini PR, Floersheimer A, Maira M, McSheehy PM. Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo. Cancer Chemother Pharmacol 2008, 62:1045-1054. 10.1007/s00280-008-0695-9, 18301895.
    • (2008) Cancer Chemother Pharmacol , vol.62 , pp. 1045-1054
    • O'Reilly, T.1    Wartmann, M.2    Brueggen, J.3    Allegrini, P.R.4    Floersheimer, A.5    Maira, M.6    McSheehy, P.M.7
  • 43
    • 35848969354 scopus 로고    scopus 로고
    • Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway
    • 10.1158/1535-7163.MCT-07-0002, 17938270
    • Lee SH, Son SM, Son DJ, Kim SM, Kim TJ, Song S, Moon DC, Lee HW, Ryu JC, Yoon DY, Hong JT. Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway. Mol Cancer Ther 2007, 6:2786-2797. 10.1158/1535-7163.MCT-07-0002, 17938270.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2786-2797
    • Lee, S.H.1    Son, S.M.2    Son, D.J.3    Kim, S.M.4    Kim, T.J.5    Song, S.6    Moon, D.C.7    Lee, H.W.8    Ryu, J.C.9    Yoon, D.Y.10    Hong, J.T.11
  • 44
    • 63349087447 scopus 로고    scopus 로고
    • NF-kappaB and ZBP-89 regulate MMP-3 expression via a polymorphic site in the promoter
    • 10.1016/j.bbrc.2009.03.002, 2678966, 19275880
    • Borghaei RC, Gorski G, Javadi M. NF-kappaB and ZBP-89 regulate MMP-3 expression via a polymorphic site in the promoter. Biochem Biophys Res Commun 2009, 382:269-273. 10.1016/j.bbrc.2009.03.002, 2678966, 19275880.
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 269-273
    • Borghaei, R.C.1    Gorski, G.2    Javadi, M.3
  • 45
    • 33750890673 scopus 로고    scopus 로고
    • Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway
    • 10.1038/sj.onc.1209706, 16732316
    • Cheng JC, Chou CH, Kuo ML, Hsieh CY. Radiation-enhanced hepatocellular carcinoma cell invasion with MMP-9 expression through PI3K/Akt/NF-kappaB signal transduction pathway. Oncogene 2006, 25:7009-7018. 10.1038/sj.onc.1209706, 16732316.
    • (2006) Oncogene , vol.25 , pp. 7009-7018
    • Cheng, J.C.1    Chou, C.H.2    Kuo, M.L.3    Hsieh, C.Y.4
  • 46
    • 33645672909 scopus 로고    scopus 로고
    • Confirmation of a linkage between H-Ras and MMP-13 expression as well as MMP-9 by chemical genomic approach
    • 10.1002/ijc.21610, 16331612
    • Lee SK, Kim JM, Lee MY, Son KH, Yeom YI, Kim CH, Shin Y, Koh JS, Han DC, Kwon BM. Confirmation of a linkage between H-Ras and MMP-13 expression as well as MMP-9 by chemical genomic approach. Int J Cancer 2006, 118:2172-2181. 10.1002/ijc.21610, 16331612.
    • (2006) Int J Cancer , vol.118 , pp. 2172-2181
    • Lee, S.K.1    Kim, J.M.2    Lee, M.Y.3    Son, K.H.4    Yeom, Y.I.5    Kim, C.H.6    Shin, Y.7    Koh, J.S.8    Han, D.C.9    Kwon, B.M.10
  • 47
    • 33748995139 scopus 로고    scopus 로고
    • Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways
    • 10.1158/0008-5472.CAN-05-4340, 16951163
    • Park CM, Park MJ, Kwak HJ, Lee HC, Kim MS, Lee SH, Park IC, Rhee CH, Hong SI. Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways. Cancer Res 2006, 66:8511-8519. 10.1158/0008-5472.CAN-05-4340, 16951163.
    • (2006) Cancer Res , vol.66 , pp. 8511-8519
    • Park, C.M.1    Park, M.J.2    Kwak, H.J.3    Lee, H.C.4    Kim, M.S.5    Lee, S.H.6    Park, I.C.7    Rhee, C.H.8    Hong, S.I.9
  • 48
    • 0033575223 scopus 로고    scopus 로고
    • The specificity of TIMP-2 for matrix metalloproteinases can be modified by single amino acid mutations
    • 10.1074/jbc.274.29.20391, 10400663
    • Butler GS, Hutton M, Wattam BA, Williamson RA, Knauper V, Willenbrock F, Murphy G. The specificity of TIMP-2 for matrix metalloproteinases can be modified by single amino acid mutations. J Biol Chem 1999, 274:20391-20396. 10.1074/jbc.274.29.20391, 10400663.
    • (1999) J Biol Chem , vol.274 , pp. 20391-20396
    • Butler, G.S.1    Hutton, M.2    Wattam, B.A.3    Williamson, R.A.4    Knauper, V.5    Willenbrock, F.6    Murphy, G.7
  • 49
    • 0041352075 scopus 로고    scopus 로고
    • The matrix metalloproteinase system: changes, regulation, and impact throughout the ovarian and uterine reproductive cycle
    • 10.1210/er.2002-0005, 12920150
    • Curry TE, Osteen KG. The matrix metalloproteinase system: changes, regulation, and impact throughout the ovarian and uterine reproductive cycle. Endocr Rev 2003, 24:428-465. 10.1210/er.2002-0005, 12920150.
    • (2003) Endocr Rev , vol.24 , pp. 428-465
    • Curry, T.E.1    Osteen, K.G.2
  • 50
    • 0028907318 scopus 로고
    • Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease
    • 10.1074/jbc.270.10.5331, 7890645
    • Strongin AY, Collier I, Bannikov G, Marmer BL, Grant GA, Goldberg GI. Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem 1995, 270:5331-5338. 10.1074/jbc.270.10.5331, 7890645.
    • (1995) J Biol Chem , vol.270 , pp. 5331-5338
    • Strongin, A.Y.1    Collier, I.2    Bannikov, G.3    Marmer, B.L.4    Grant, G.A.5    Goldberg, G.I.6
  • 51
    • 0034615550 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases: evolution, structure and function
    • 10.1016/S0167-4838(99)00279-4, 10708863
    • Brew K, Dinakarpandian D, Nagase H. Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim Biophys Acta 2000, 1477:267-283. 10.1016/S0167-4838(99)00279-4, 10708863.
    • (2000) Biochim Biophys Acta , vol.1477 , pp. 267-283
    • Brew, K.1    Dinakarpandian, D.2    Nagase, H.3
  • 52
    • 34748884398 scopus 로고    scopus 로고
    • Chemoradiotherapy in malignant glioma: standard of care and future directions
    • 10.1200/JCO.2007.11.8554, 17827463
    • Stupp R, Hegi ME, Gilbert MR, Chakravarti A. Chemoradiotherapy in malignant glioma: standard of care and future directions. J Clin Oncol 2007, 25:4127-4136. 10.1200/JCO.2007.11.8554, 17827463.
    • (2007) J Clin Oncol , vol.25 , pp. 4127-4136
    • Stupp, R.1    Hegi, M.E.2    Gilbert, M.R.3    Chakravarti, A.4
  • 53
    • 0033038483 scopus 로고    scopus 로고
    • Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas
    • 10.1038/sj.bjc.6690291, 2362801, 10206300
    • Forsyth PA, Wong H, Laing TD, Rewcastle NB, Morris DG, Muzik H, Leco KJ, Johnston RN, Brasher PM, Sutherland G, Edwards DR. Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. Br J Cancer 1999, 79:1828-1835. 10.1038/sj.bjc.6690291, 2362801, 10206300.
    • (1999) Br J Cancer , vol.79 , pp. 1828-1835
    • Forsyth, P.A.1    Wong, H.2    Laing, T.D.3    Rewcastle, N.B.4    Morris, D.G.5    Muzik, H.6    Leco, K.J.7    Johnston, R.N.8    Brasher, P.M.9    Sutherland, G.10    Edwards, D.R.11
  • 54
    • 0035866813 scopus 로고    scopus 로고
    • Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma
    • Wild-Bode C, Weller M, Rimner A, Dichgans J, Wick W. Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma. Cancer Res 2001, 61:2744-2750.
    • (2001) Cancer Res , vol.61 , pp. 2744-2750
    • Wild-Bode, C.1    Weller, M.2    Rimner, A.3    Dichgans, J.4    Wick, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.