메뉴 건너뛰기




Volumn 133, Issue 1, 2013, Pages 42-53

TCDD inhibition of canonical wnt signaling disrupts prostatic bud formation in mouse urogenital sinus

Author keywords

Bud; Canonical Wnt; Development; Mouse; Prostate; R spondin; TCDD; Urogenital sinus

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; DICKKOPF 1 PROTEIN; DKK2 PROTEIN; LGR5 PROTEIN; LYMPHOID ENHANCER FACTOR 1; PEPTIDES AND PROTEINS; RSPO2 PROTEIN; RSPO3 PROTEIN; TRANSCRIPTION FACTOR 7; UNCLASSIFIED DRUG; WIF1 PROTEIN; WNT PROTEIN;

EID: 84876805135     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft027     Document Type: Article
Times cited : (19)

References (45)
  • 1
    • 80052965910 scopus 로고    scopus 로고
    • A high-resolution molecular atlas of the fetal mouse lower urogenital tract
    • Abler, L. L., Keil, K. P., Mehta, V., Joshi, P. S., Schmitz, C. T., and Vezina, C. M. (2011). A high-resolution molecular atlas of the fetal mouse lower urogenital tract. Dev. Dyn. 240, 2364-2377.
    • (2011) Dev. Dyn. , vol.240 , pp. 2364-2377
    • Abler, L.L.1    Keil, K.P.2    Mehta, V.3    Joshi, P.S.4    Schmitz, C.T.5    Vezina, C.M.6
  • 4
    • 84864021917 scopus 로고    scopus 로고
    • LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/ß-catenin signaling
    • Carmon, K. S., Lin, Q., Gong, X., Thomas, A., and Liu, Q. (2011). LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/ß-catenin signaling. Mol. Cell. Biol. 32, 2054-2064.
    • (2011) Mol. Cell. Biol. , vol.32 , pp. 2054-2064
    • Carmon, K.S.1    Lin, Q.2    Gong, X.3    Thomas, A.4    Liu, Q.5
  • 5
    • 0019799945 scopus 로고
    • Stromal-epithelial interactions-I, Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice
    • Cunha, G. R., and Chung, L. W. (1981). Stromal-epithelial interactions-I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice. J. Steroid Biochem. 14, 1317-1324.
    • (1981) J. Steroid Biochem. , vol.14 , pp. 1317-1324
    • Cunha, G.R.1    Chung, L.W.2
  • 7
    • 0042162919 scopus 로고    scopus 로고
    • FGF-10 plays an essential role in the growth of the fetal prostate
    • Donjacour, A. A., Thomson, A. A., and Cunha, G. R. (2003). FGF-10 plays an essential role in the growth of the fetal prostate. Dev. Biol. 261, 39-54.
    • (2003) Dev. Biol. , vol.261 , pp. 39-54
    • Donjacour, A.A.1    Thomson, A.A.2    Cunha, G.R.3
  • 9
    • 0037031887 scopus 로고    scopus 로고
    • Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter
    • Filali, M., Cheng, N., Abbott, D., Leontiev, V., and Engelhardt, J. F. (2002). Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter. J. Biol. Chem. 277, 33398-33410.
    • (2002) J. Biol. Chem. , vol.277 , pp. 33398-33410
    • Filali, M.1    Cheng, N.2    Abbott, D.3    Leontiev, V.4    Engelhardt, J.F.5
  • 10
    • 84873486287 scopus 로고    scopus 로고
    • ß-Catenin is required for prostate development and cooperates with pten loss to drive invasive carcinoma
    • Francis, J. C., Thomsen, M. K., Taketo, M. M., and Swain, A. (2013). ß-Catenin is required for prostate development and cooperates with pten loss to drive invasive carcinoma. PLoS Genet. 9, e1003180.
    • (2013) PLoS Genet , vol.9
    • Francis, J.C.1    Thomsen, M.K.2    Taketo, M.M.3    Swain, A.4
  • 11
    • 0032567078 scopus 로고    scopus 로고
    • De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated betacatenin in skin
    • Gat, U., DasGupta, R., Degenstein, L., and Fuchs, E. (1998). De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated betacatenin in skin. Cell 95, 605-614.
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    DasGupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 13
    • 80052088782 scopus 로고    scopus 로고
    • Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands
    • Hrubá, E., Vondrácek, J., Líbalová, H., Topinka, J., Bryja, V., Soucek, K., and Machala, M. (2011). Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands. Toxicol. Lett. 206, 178-188.
    • (2011) Toxicol. Lett. , vol.206 , pp. 178-188
    • Hrubá, E.1    Vondrácek, J.2    Líbalová, H.3    Topinka, J.4    Bryja, V.5    Soucek, K.6    Machala, M.7
  • 14
    • 77954483370 scopus 로고    scopus 로고
    • The effects of Wnt inhibitors on the chondrogenesis of human mesenchymal stem cells
    • Im, G. I., and Quan, Z. (2010). The effects of Wnt inhibitors on the chondrogenesis of human mesenchymal stem cells. Tissue Eng. Part A 16, 2405-2413.
    • (2010) Tissue Eng. Part A , vol.16 , pp. 2405-2413
    • Im, G.I.1    Quan, Z.2
  • 16
    • 33947148128 scopus 로고    scopus 로고
    • Qualitative effects of dioxin on molars vary among inbred mouse strains
    • Keller, J. M., Huet-Hudson, Y. M., and Leamy, L. J. (2007). Qualitative effects of dioxin on molars vary among inbred mouse strains. Arch. Oral Biol. 52, 450-454.
    • (2007) Arch. Oral Biol. , vol.52 , pp. 450-454
    • Keller, J.M.1    Huet-Hudson, Y.M.2    Leamy, L.J.3
  • 19
    • 1642315754 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptors in urogenital sinus mesenchyme mediate the inhibition of prostatic epithelial bud formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Ko, K., Moore, R. W., and Peterson, R. E. (2004a). Aryl hydrocarbon receptors in urogenital sinus mesenchyme mediate the inhibition of prostatic epithelial bud formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 196, 149-155.
    • (2004) Toxicol. Appl. Pharmacol. , vol.196 , pp. 149-155
    • Ko, K.1    Moore, R.W.2    Peterson, R.E.3
  • 20
    • 2942720929 scopus 로고    scopus 로고
    • Evidence that inhibited prostatic epithelial bud formation in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed C57BL/6J fetal mice is not due to interruption of androgen signaling in the urogenital sinus
    • Ko, K., Theobald, H. M., Moore, R. W., and Peterson, R. E. (2004b). Evidence that inhibited prostatic epithelial bud formation in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed C57BL/6J fetal mice is not due to interruption of androgen signaling in the urogenital sinus. Toxicol. Sci. 79, 360-369.
    • (2004) Toxicol. Sci. , vol.79 , pp. 360-369
    • Ko, K.1    Theobald, H.M.2    Moore, R.W.3    Peterson, R.E.4
  • 21
    • 12244310508 scopus 로고    scopus 로고
    • In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in the C57BL/6J mouse prostate: Lobe-specific effects on branching morphogenesis
    • Ko, K., Theobald, H. M., and Peterson, R. E. (2002). In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in the C57BL/6J mouse prostate: Lobe-specific effects on branching morphogenesis. Toxicol. Sci. 70, 227-237.
    • (2002) Toxicol. Sci. , vol.70 , pp. 227-237
    • Ko, K.1    Theobald, H.M.2    Peterson, R.E.3
  • 22
    • 84866169711 scopus 로고    scopus 로고
    • Wnt signaling genes of murine chromosome 15 are involved in sex-affected pathways of inflammatory arthritis
    • Kudryavtseva, E., Forde, T. S., Pucker, A. D., and Adarichev, V. A. (2011). Wnt signaling genes of murine chromosome 15 are involved in sex-affected pathways of inflammatory arthritis. Arthritis Rheum. 64, 1057-1068.
    • (2011) Arthritis Rheum , vol.64 , pp. 1057-1068
    • Kudryavtseva, E.1    Forde, T.S.2    Pucker, A.D.3    Adarichev, V.A.4
  • 23
    • 77951741901 scopus 로고    scopus 로고
    • Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice
    • La Merrill, M., Harper, R., Birnbaum, L. S., Cardiff, R. D., and Threadgill, D. W. (2010). Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice. Environ. Health Perspect. 118, 596-601.
    • (2010) Environ. Health Perspect. , vol.118 , pp. 596-601
    • La Merrill, M.1    Harper, R.2    Birnbaum, L.S.3    Cardiff, R.D.4    Threadgill, D.W.5
  • 24
    • 0242331702 scopus 로고    scopus 로고
    • Region-specific inhibition of prostatic epithelial bud formation in the urogenital sinus of C57BL/6 mice exposed in utero to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Lin, T. M., Rasmussen, N. T., Moore, R. W., Albrecht, R. M., and Peterson, R. E. (2003). Region-specific inhibition of prostatic epithelial bud formation in the urogenital sinus of C57BL/6 mice exposed in utero to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 76, 171-181.
    • (2003) Toxicol. Sci. , vol.76 , pp. 171-181
    • Lin, T.M.1    Rasmussen, N.T.2    Moore, R.W.3    Albrecht, R.M.4    Peterson, R.E.5
  • 25
    • 0036740210 scopus 로고    scopus 로고
    • Critical windows of vulnerability for effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on prostate and seminal vesicle development in C57BL/6 mice
    • Lin, T. M., Simanainen, U., Moore, R. W., and Peterson, R. E. (2002). Critical windows of vulnerability for effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on prostate and seminal vesicle development in C57BL/6 mice. Toxicol. Sci. 69, 202-209.
    • (2002) Toxicol. Sci. , vol.69 , pp. 202-209
    • Lin, T.M.1    Simanainen, U.2    Moore, R.W.3    Peterson, R.E.4
  • 27
    • 2342427631 scopus 로고    scopus 로고
    • Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
    • Lo Celso, C., Prowse, D. M., and Watt, F. M. (2004). Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development 131, 1787-1799.
    • (2004) Development , vol.131 , pp. 1787-1799
    • Lo Celso, C.1    Prowse, D.M.2    Watt, F.M.3
  • 28
    • 48749116552 scopus 로고    scopus 로고
    • Crosstalk between AHR and Wnt signaling through R-Spondin1 impairs tissue regeneration in zebrafish
    • Mathew, L. K., Sengupta, S. S., Ladu, J., Andreasen, E. A., and Tanguay, R. L. (2008). Crosstalk between AHR and Wnt signaling through R-Spondin1 impairs tissue regeneration in zebrafish. FASEB J. 22, 3087-3096.
    • (2008) FASEB J , vol.22 , pp. 3087-3096
    • Mathew, L.K.1    Sengupta, S.S.2    Ladu, J.3    Andreasen, E.A.4    Tanguay, R.L.5
  • 29
    • 80054844839 scopus 로고    scopus 로고
    • Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract
    • Mehta, V., Abler, L. L., Keil, K. P., Schmitz, C. T., Joshi, P. S., and Vezina, C. M. (2011). Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract. Dev. Dyn. 240, 2548-2560.
    • (2011) Dev. Dyn. , vol.240 , pp. 2548-2560
    • Mehta, V.1    Abler, L.L.2    Keil, K.P.3    Schmitz, C.T.4    Joshi, P.S.5    Vezina, C.M.6
  • 30
    • 84875055629 scopus 로고    scopus 로고
    • Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning
    • Mehta, V., Schmitz, C. T., Keil, K. P., Joshi, P. S., Abler, L. L., Lin, T.-M., Taketo, M. M., Sun, X., and Vezina, C. M. (2013). Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. Dev. Biol. 376, 125-135.
    • (2013) Dev. Biol. , vol.376 , pp. 125-135
    • Mehta, V.1    Schmitz, C.T.2    Keil, K.P.3    Joshi, P.S.4    Abler, L.L.5    Lin, T.-M.6    Taketo, M.M.7    Sun, X.8    Vezina, C.M.9
  • 31
    • 84886723968 scopus 로고    scopus 로고
    • Identification of Wnt and Rspo genes whose expression patterns in fetal mouse urogential sinus (UGS) are altered by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Moore, R. W., Abler, L. L., Mehta, V., Vezina, C. M., and Peterson, R. E. (2011). Identification of Wnt and Rspo genes whose expression patterns in fetal mouse urogential sinus (UGS) are altered by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol. Sci. 120(suppl), 350.
    • (2011) Toxicol. Sci. , vol.120 , Issue.SUPPL. , pp. 350
    • Moore, R.W.1    Abler, L.L.2    Mehta, V.3    Vezina, C.M.4    Peterson, R.E.5
  • 32
    • 33744964431 scopus 로고    scopus 로고
    • Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
    • Nam, J. S., Turcotte, T. J., Smith, P. F., Choi, S., and Yoon, J. K. (2006). Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J. Biol. Chem. 281, 13247-13257.
    • (2006) J. Biol. Chem. , vol.281 , pp. 13247-13257
    • Nam, J.S.1    Turcotte, T.J.2    Smith, P.F.3    Choi, S.4    Yoon, J.K.5
  • 33
    • 33845359084 scopus 로고    scopus 로고
    • Function and biological roles of the Dickkopf family of Wnt modulators
    • Niehrs, C. (2006). Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 25, 7469-7481.
    • (2006) Oncogene , vol.25 , pp. 7469-7481
    • Niehrs, C.1
  • 34
    • 0031043421 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCCD) affects keratin 1 and keratin 17 gene expression and differentially induces keratinization in hairless mouse skin
    • Panteleyev, A. A., Thiel, R., Wanner, R., Zhang, J., Roumak, V. S., Paus, R., Neubert, D., Henz, B. M., and Rosenbach, T. (1997). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCCD) affects keratin 1 and keratin 17 gene expression and differentially induces keratinization in hairless mouse skin. J. Invest. Dermatol. 108, 330-335.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 330-335
    • Panteleyev, A.A.1    Thiel, R.2    Wanner, R.3    Zhang, J.4    Roumak, V.S.5    Paus, R.6    Neubert, D.7    Henz, B.M.8    Rosenbach, T.9
  • 35
    • 80051702065 scopus 로고    scopus 로고
    • The interplay of the aryl hydrocarbon receptor and β-catenin alters both AhR-dependent transcription and Wnt/β-catenin signaling in liver progenitors
    • Procházková, J., Kabátková, M., Bryja, V., Umannová, L., Bernatík, O., Kozubík, A., Machala, M., and Vondrácek, J. (2011). The interplay of the aryl hydrocarbon receptor and β-catenin alters both AhR-dependent transcription and Wnt/β-catenin signaling in liver progenitors. Toxicol. Sci. 122, 349-360.
    • (2011) Toxicol. Sci. , vol.122 , pp. 349-360
    • Procházková, J.1    Kabátková, M.2    Bryja, V.3    Umannová, L.4    Bernatík, O.5    Kozubík, A.6    Machala, M.7    Vondrácek, J.8
  • 36
    • 0032830931 scopus 로고    scopus 로고
    • TCF transcription factors: Molecular switches in carcinogenesis
    • Roose, J., and Clevers, H. (1999). TCF transcription factors: Molecular switches in carcinogenesis. Biochim. Biophys. Acta 1424, M23-M37.
    • (1999) Biochim. Biophys. Acta , vol.1424
    • Roose, J.1    Clevers, H.2
  • 38
    • 0028962717 scopus 로고
    • Instructive induction of prostate growth and differentiation by a defined urogenital sinus mesenchyme
    • Timms, B. G., Lee, C. W., Aumüller, G., and Seitz, J. (1995). Instructive induction of prostate growth and differentiation by a defined urogenital sinus mesenchyme. Microsc. Res. Tech. 30, 319-332.
    • (1995) Microsc. Res. Tech. , vol.30 , pp. 319-332
    • Timms, B.G.1    Lee, C.W.2    Aumüller, G.3    Seitz, J.4
  • 39
    • 0028326109 scopus 로고
    • Ductal budding and branching patterns in the developing prostate
    • Timms, B. G., Mohs, T. J., and Didio, L. J. (1994). Ductal budding and branching patterns in the developing prostate. J. Urol. 151, 1427-1432.
    • (1994) J. Urol. , vol.151 , pp. 1427-1432
    • Timms, B.G.1    Mohs, T.J.2    Didio, L.J.3
  • 40
    • 84856704954 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway
    • Tsang, H., Cheung, T. Y., Kodithuwakku, S. P., Chai, J., Yeung, W. S., Wong, C. K., and Lee, K. F. (2012). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. Reprod. Toxicol. 33, 60-66.
    • (2012) Reprod. Toxicol. , vol.33 , pp. 60-66
    • Tsang, H.1    Cheung, T.Y.2    Kodithuwakku, S.P.3    Chai, J.4    Yeung, W.S.5    Wong, C.K.6    Lee, K.F.7
  • 43
    • 75249087916 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits fibroblast growth factor 10-induced prostatic bud formation in mouse urogenital sinus
    • Vezina, C. M., Hardin, H. A., Moore, R. W., Allgeier, S. H., and Peterson, R. E. (2009). 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits fibroblast growth factor 10-induced prostatic bud formation in mouse urogenital sinus. Toxicol. Sci. 113, 198-206.
    • (2009) Toxicol. Sci. , vol.113 , pp. 198-206
    • Vezina, C.M.1    Hardin, H.A.2    Moore, R.W.3    Allgeier, S.H.4    Peterson, R.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.