-
1
-
-
0042405132
-
Recognition of microbial infection by Toll-like receptors
-
Kopp E., Medzhitov R. Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol 2003, 15:396-401.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 396-401
-
-
Kopp, E.1
Medzhitov, R.2
-
2
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
-
Poltorak A., He X., Smirnova I., Liu M.Y., Van Huffel C., Du X., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998, 282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
-
3
-
-
0031776896
-
LPS-binding proteins and receptors
-
Fenton M.J., Golenbock D.T. LPS-binding proteins and receptors. J Leukoc Biol 1998, 64:25-32.
-
(1998)
J Leukoc Biol
, vol.64
, pp. 25-32
-
-
Fenton, M.J.1
Golenbock, D.T.2
-
4
-
-
0037071251
-
Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
-
Lorenz E., Mira J.P., Frees K.L., Schwartz D.A. Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 2002, 162:1028-1032.
-
(2002)
Arch Intern Med
, vol.162
, pp. 1028-1032
-
-
Lorenz, E.1
Mira, J.P.2
Frees, K.L.3
Schwartz, D.A.4
-
5
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburt P., Janeway C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997, 388:394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway, C.A.3
-
6
-
-
0038242875
-
Toll-like receptor signaling pathways
-
Barton G.M., Medzhitov R. Toll-like receptor signaling pathways. Science 2003, 300:1524-1525.
-
(2003)
Science
, vol.300
, pp. 1524-1525
-
-
Barton, G.M.1
Medzhitov, R.2
-
7
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R., Preston-Hurlburt P., Kopp E., Stadlen A., Chen C., Ghosh S., et al. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell 1998, 2:253-258.
-
(1998)
Mol Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
-
8
-
-
53349164136
-
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
-
Sorrentino A., Thakur N., Grimsby S., Marcusson A., von Bulow V., Schuster N., et al. The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nat Cell Biol 2008, 10:1199-1207.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1199-1207
-
-
Sorrentino, A.1
Thakur, N.2
Grimsby, S.3
Marcusson, A.4
von Bulow, V.5
Schuster, N.6
-
9
-
-
66249129026
-
TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA
-
Konno H., Yamamoto T., Yamazaki K., Gohda J., Akiyama T., Semba K., et al. TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA. PLoS One 2009, 4:e5674.
-
(2009)
PLoS One
, vol.4
-
-
Konno, H.1
Yamamoto, T.2
Yamazaki, K.3
Gohda, J.4
Akiyama, T.5
Semba, K.6
-
10
-
-
0033559420
-
Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production
-
Jang D.S., Kang B.S., Ryu S.Y., Chang I.M., Min K.R., Kim Y. Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production. Biochem Pharmacol 1999, 57:705-712.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 705-712
-
-
Jang, D.S.1
Kang, B.S.2
Ryu, S.Y.3
Chang, I.M.4
Min, K.R.5
Kim, Y.6
-
11
-
-
0033952265
-
Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production
-
Martinez J., Moreno J.J. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production. Biochem Pharmacol 2000, 59:865-870.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 865-870
-
-
Martinez, J.1
Moreno, J.J.2
-
12
-
-
15444353694
-
Effect of trans-resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function
-
Rotondo S., Rajtar G., Manarini S., Celardo A., Rotillo D., de Gaetano G., et al. Effect of trans-resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function. Br J Pharmacol 1998, 123:1691-1699.
-
(1998)
Br J Pharmacol
, vol.123
, pp. 1691-1699
-
-
Rotondo, S.1
Rajtar, G.2
Manarini, S.3
Celardo, A.4
Rotillo, D.5
de Gaetano, G.6
-
13
-
-
0034234254
-
Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase
-
Holmes-McNary M., Baldwin A.S. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Res 2000, 60:3477-3483.
-
(2000)
Cancer Res
, vol.60
, pp. 3477-3483
-
-
Holmes-McNary, M.1
Baldwin, A.S.2
-
14
-
-
0034660659
-
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation
-
Manna S.K., Mukhopadhyay A., Aggarwal B.B. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J Immunol 2000, 164:6509-6519.
-
(2000)
J Immunol
, vol.164
, pp. 6509-6519
-
-
Manna, S.K.1
Mukhopadhyay, A.2
Aggarwal, B.B.3
-
15
-
-
80052910300
-
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients
-
Brasnyo P., Molnar G.A., Mohas M., Marko L., Laczy B., Cseh J., et al. Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. Br J Nutr 2011, 106:383-389.
-
(2011)
Br J Nutr
, vol.106
, pp. 383-389
-
-
Brasnyo, P.1
Molnar, G.A.2
Mohas, M.3
Marko, L.4
Laczy, B.5
Cseh, J.6
-
16
-
-
1542723466
-
Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta
-
Jiang Z., Mak T.W., Sen G., Li X. Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta. Proc Natl Acad Sci U S A 2004, 101:3533-3538.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3533-3538
-
-
Jiang, Z.1
Mak, T.W.2
Sen, G.3
Li, X.4
-
17
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling
-
Sato S., Sugiyama M., Yamamoto M., Watanabe Y., Kawai T., Takeda K., et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J Immunol 2003, 171:4304-4310.
-
(2003)
J Immunol
, vol.171
, pp. 4304-4310
-
-
Sato, S.1
Sugiyama, M.2
Yamamoto, M.3
Watanabe, Y.4
Kawai, T.5
Takeda, K.6
-
18
-
-
23844478190
-
Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex
-
Youn H.S., Lee J.Y., Fitzgerald K.A., Young H.A., Akira S., Hwang D.H. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex. J Immunol 2005, 175:3339-3346.
-
(2005)
J Immunol
, vol.175
, pp. 3339-3346
-
-
Youn, H.S.1
Lee, J.Y.2
Fitzgerald, K.A.3
Young, H.A.4
Akira, S.5
Hwang, D.H.6
-
19
-
-
4344613405
-
Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling
-
Gohda J., Matsumura T., Inoue J. Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling. J Immunol 2004, 173:2913-2917.
-
(2004)
J Immunol
, vol.173
, pp. 2913-2917
-
-
Gohda, J.1
Matsumura, T.2
Inoue, J.3
-
20
-
-
60249100175
-
Ferulaldehyde, a water-soluble degradation product of polyphenols, inhibits the lipopolysaccharide-induced inflammatory response in mice
-
Radnai B., Tucsek Z., Bognar Z., Antus C., Mark L., Berente Z., et al. Ferulaldehyde, a water-soluble degradation product of polyphenols, inhibits the lipopolysaccharide-induced inflammatory response in mice. J Nutr 2009, 139:291-297.
-
(2009)
J Nutr
, vol.139
, pp. 291-297
-
-
Radnai, B.1
Tucsek, Z.2
Bognar, Z.3
Antus, C.4
Mark, L.5
Berente, Z.6
-
21
-
-
79251573866
-
Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP-1
-
Tucsek Z., Radnai B., Racz B., Debreceni B., Priber J.K., Dolowschiak T., et al. Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP-1. J Leukoc Biol 2011, 89:105-111.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 105-111
-
-
Tucsek, Z.1
Radnai, B.2
Racz, B.3
Debreceni, B.4
Priber, J.K.5
Dolowschiak, T.6
-
22
-
-
34249329607
-
Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages
-
Loniewski K.J., Patial S., Parameswaran N. Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages. Mol Immunol 2007, 44:3715-3723.
-
(2007)
Mol Immunol
, vol.44
, pp. 3715-3723
-
-
Loniewski, K.J.1
Patial, S.2
Parameswaran, N.3
-
23
-
-
4344712350
-
TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains
-
Kanayama A., Seth R.B., Sun L., Ea C.K., Hong M., Shaito A., et al. TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell 2004, 15:535-548.
-
(2004)
Mol Cell
, vol.15
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
Ea, C.K.4
Hong, M.5
Shaito, A.6
-
24
-
-
2342629277
-
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
-
Sun L., Deng L., Ea C.K., Xia Z.P., Chen Z.J. The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell 2004, 14:289-301.
-
(2004)
Mol Cell
, vol.14
, pp. 289-301
-
-
Sun, L.1
Deng, L.2
Ea, C.K.3
Xia, Z.P.4
Chen, Z.J.5
-
25
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng L., Wang C., Spencer E., Yang L., Braun A., You J., et al. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 2000, 103:351-361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
You, J.6
-
26
-
-
0035868884
-
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis
-
Kobayashi N., Kadono Y., Naito A., Matsumoto K., Yamamoto T., Tanaka S., et al. Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO J 2001, 20:1271-1280.
-
(2001)
EMBO J
, vol.20
, pp. 1271-1280
-
-
Kobayashi, N.1
Kadono, Y.2
Naito, A.3
Matsumoto, K.4
Yamamoto, T.5
Tanaka, S.6
-
27
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C., Deng L., Hong M., Akkaraju G.R., Inoue J., Chen Z.J. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 2001, 412:346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
28
-
-
69549116880
-
The E3 ligase TRAF6 regulates Akt ubiquitination and activation
-
Yang W.L., Wang J., Chan C.H., Lee S.W., Campos A.D., Lamothe B., et al. The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science 2009, 325:1134-1138.
-
(2009)
Science
, vol.325
, pp. 1134-1138
-
-
Yang, W.L.1
Wang, J.2
Chan, C.H.3
Lee, S.W.4
Campos, A.D.5
Lamothe, B.6
-
29
-
-
0034598322
-
1,1-Dimethylallylcoumarins potently suppress both lipopolysaccharide- and interferon-gamma-induced nitric oxide generation in mouse macrophage RAW 264.7 cells
-
Murakami A., Gao G., Omura M., Yano M., Ito C., Furukawa H., et al. 1,1-Dimethylallylcoumarins potently suppress both lipopolysaccharide- and interferon-gamma-induced nitric oxide generation in mouse macrophage RAW 264.7 cells. Bioorg Med Chem Lett 2000, 10:59-62.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 59-62
-
-
Murakami, A.1
Gao, G.2
Omura, M.3
Yano, M.4
Ito, C.5
Furukawa, H.6
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