메뉴 건너뛰기




Volumn 35, Issue 5-6, 2013, Pages 340-350

Aromatase variants modify risk for Alzheimer's disease in a multiethnic female cohort

Author keywords

Alzheimer's disease; Alzheimer's disease and Hispanics; CYP19 gene; Estrogen; Genetic polymorphisms in degenerative dementias; Genetic risk factors

Indexed keywords

APOENZYME; AROMATASE;

EID: 84876797916     PISSN: 14208008     EISSN: 14219824     Source Type: Journal    
DOI: 10.1159/000343074     Document Type: Article
Times cited : (24)

References (31)
  • 1
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-alpha and-beta mRNA in the rat central nervous system
    • Shughrue PJ, Lane MV, Merchenthaler I: Comparative distribution of estrogen receptor-alpha and-beta mRNA in the rat central nervous system. J Comp Neurol 1997; 388: 507-525.
    • (1997) J Comp Neurol , vol.388 , pp. 507-525
    • Shughrue, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 2
    • 0035180875 scopus 로고    scopus 로고
    • Invited review: Estrogen effects on the brain: Multiple sites and molecular mechanisms
    • McEwen BS: Invited review: estrogen effects on the brain: multiple sites and molecular mechanisms. J Appl Physiol 2001; 91: 2785-2801.
    • (2001) J Appl Physiol , vol.91 , pp. 2785-2801
    • McEwen, B.S.1
  • 4
    • 34247094924 scopus 로고    scopus 로고
    • CYP19 haplotypes increase risk for Alzheimer's disease
    • Huang R, Poduslo SE: CYP19 haplotypes increase risk for Alzheimer's disease. J Med Genet 2006; 43:e42.
    • (2006) J Med Genet , vol.43 , pp. e42
    • Huang, R.1    Poduslo, S.E.2
  • 7
    • 66149122258 scopus 로고    scopus 로고
    • Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women
    • Corbo RM, Gambina G, Ulizzi L, Moretto G, Scacchi R: Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women. Dement Geriatr Cogn Disord 2009; 27: 513-518.
    • (2009) Dement Geriatr Cogn Disord , vol.27 , pp. 513-518
    • Corbo, R.M.1    Gambina, G.2    Ulizzi, L.3    Moretto, G.4    Scacchi, R.5
  • 8
    • 33845892752 scopus 로고    scopus 로고
    • Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
    • Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE: Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 2007; 39: 17-23.
    • (2007) Nat Genet , vol.39 , pp. 17-23
    • Bertram, L.1    McQueen, M.B.2    Mullin, K.3    Blacker, D.4    Tanzi, R.E.5
  • 10
    • 0026690012 scopus 로고
    • Diagnosis of dementia in a heterogeneous population. Development of a neuropsychological paradigm-based diagnosis of dementia and quantified correction for the effects of education
    • Stern Y, Andrews H, Pittman J, Sano M, Tatemichi T, Lantigua R, Mayeux R: Diagnosis of dementia in a heterogeneous population. Development of a neuropsychological paradigm-based diagnosis of dementia and quantified correction for the effects of education. Arch Neurol 1992; 49: 453-460.
    • (1992) Arch Neurol , vol.49 , pp. 453-460
    • Stern, Y.1    Andrews, H.2    Pittman, J.3    Sano, M.4    Tatemichi, T.5    Lantigua, R.6    Mayeux, R.7
  • 11
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard JK, Stephens M, Donnelly P: Inference of population structure using multilocus genotype data. Genetics 2000;155: 945-959.
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 12
    • 0041817568 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data: Linked loci and correlated allele frequencies
    • Falush D, Stephens M, Pritchard JK: Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 2003; 164: 1567-1587.
    • (2003) Genetics , vol.164 , pp. 1567-1587
    • Falush, D.1    Stephens, M.2    Pritchard, J.K.3
  • 13
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein e by gene amplification and cleavage with Hhai
    • Hixson JE, Vernier DT: Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hhai. J Lipid Res 1990; 31: 545-548.
    • (1990) J Lipid Res , vol.31 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 14
    • 0029924284 scopus 로고    scopus 로고
    • Estrogens attenuate and corticosterone exacerbates excitotox-icity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons
    • Goodman Y, Bruce AJ, Cheng B, Mattson MP: Estrogens attenuate and corticosterone exacerbates excitotox-icity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons. J Neurochem 1996; 66: 1836-1844.
    • (1996) J Neurochem , vol.66 , pp. 1836-1844
    • Goodman, Y.1    Bruce, A.J.2    Cheng, B.3    Mattson, M.P.4
  • 16
    • 0021861330 scopus 로고
    • Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats
    • Luine VN: Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats. Exp Neurol 1985; 89: 484-490.
    • (1985) Exp Neurol , vol.89 , pp. 484-490
    • Luine, V.N.1
  • 17
    • 0028971169 scopus 로고
    • 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro
    • Behl C, Widmann M, Trapp T, Holsboer F: 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun 1995; 216: 473-482.
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 473-482
    • Behl, C.1    Widmann, M.2    Trapp, T.3    Holsboer, F.4
  • 18
    • 0028342424 scopus 로고
    • Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein
    • Jaffe AB, Toran-Allerand CD, Greengard P, Gandy SE: Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein. J Biol Chem 1994; 269: 13065-13068.
    • (1994) J Biol Chem , vol.269 , pp. 13065-13068
    • Jaffe, A.B.1    Toran-Allerand, C.D.2    Greengard, P.3    Gandy, S.E.4
  • 19
    • 0029019735 scopus 로고
    • How do we explain the clinical benefits of estrogen? from bedside to bench
    • Gerhard M, Ganz P: How do we explain the clinical benefits of estrogen? From bedside to bench. Circulation 1995; 92: 5-8.
    • (1995) Circulation , vol.92 , pp. 5-8
    • Gerhard, M.1    Ganz, P.2
  • 20
    • 33847770935 scopus 로고    scopus 로고
    • Rapid estrogen actions in the cardiovascular system
    • Simoncini T, Mannella P, Genazzani AR: Rapid estrogen actions in the cardiovascular system. Ann NY Acad Sci 2006; 1089: 424-430.
    • (2006) Ann NY Acad Sci , vol.1089 , pp. 424-430
    • Simoncini, T.1    Mannella, P.2    Genazzani, A.R.3
  • 21
    • 34548536149 scopus 로고    scopus 로고
    • Estrogen receptor alpha and its splice variants in the hippocampus in aging and Alzheimer's disease
    • Ishunina TA, Fischer DF, Swaab DF: Estrogen receptor alpha and its splice variants in the hippocampus in aging and Alzheimer's disease. Neurobiol Aging 2007; 28: 1670-1681.
    • (2007) Neurobiol Aging , vol.28 , pp. 1670-1681
    • Ishunina, T.A.1    Fischer, D.F.2    Swaab, D.F.3
  • 27
    • 14044269979 scopus 로고    scopus 로고
    • Re: Polymorphisms associated with circulating sex hormone levels in postmenopausal women
    • author reply 153-154
    • De Castro F, Moron FJ, Montoro L, Galan JJ, Real LM, Ruiz A: Re: Polymorphisms associated with circulating sex hormone levels in postmenopausal women. J Natl Cancer Inst 2005; 97: 152-153; author reply 153-154.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 152-153
    • De Castro, F.1    Moron, F.J.2    Montoro, L.3    Galan, J.J.4    Real, L.M.5    Ruiz, A.6
  • 31
    • 77957597251 scopus 로고    scopus 로고
    • Genome-wide association reveals genetic effects on human Aβ42 and tau protein levels in cerebrospinal fluids: A case control study
    • Han MR, Schellenberg GD, Wang LS: Genome-wide association reveals genetic effects on human Aβ42 and tau protein levels in cerebrospinal fluids: a case control study. BMC Neurol 2010; 10: 90.
    • (2010) BMC Neurol , vol.10 , pp. 90
    • Han, M.R.1    Schellenberg, G.D.2    Wang, L.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.