MEK inhibition leads to lysosomemediated Na+/I- symporter protein degradation in human breast cancer cells

Endocrine-Related Cancer

Volumn 20, Issue 2, 2013, Pages 241-250

  Zhang, Zhaoxia ^a,b   Beyer, Sasha ^a,c   Jhiang, Sissy M ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b Chemical Abstracts Service   (United States)

^c MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Breast; Cancer; Lysosome; MEK; NIS

Indexed keywords

HYDROCORTISONE; IODIDE; MITOGEN ACTIVATED PROTEIN KINASE; RETINOIC ACID; SODIUM GLUCOSE COTRANSPORTER; SODIUM GLUCOSE COTRANSPORTER 5; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LYSOSOME; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

BREAST NEOPLASMS; BUTADIENES; CELL LINE, TUMOR; HUMANS; HYDROCORTISONE; IODIDES; LYSOSOMES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITRILES; PROTEIN KINASE INHIBITORS; PROTEOLYSIS; RNA, MESSENGER; SYMPORTERS; TRETINOIN;

EID: 84876749475     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-12-0342     Document Type: Article

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