메뉴 건너뛰기




Volumn 19, Issue 15, 2013, Pages 2728-2736

Ellagic acid: Cytodifferentiating and antiproliferative effects in human prostatic cancer cell lines

Author keywords

Apoptosis; Cytodifferentiation; Ellagic acid; Prostate cancer

Indexed keywords

CHROMOGRANIN A; DNA; DNA METHYLTRANSFERASE 1; ELLAGIC ACID; NEUROTROPHIN RECEPTOR P75; PROTEIN KINASE B; RETINOBLASTOMA PROTEIN;

EID: 84876728812     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319150008     Document Type: Article
Times cited : (30)

References (72)
  • 1
    • 0034667386 scopus 로고    scopus 로고
    • Reduced infiltration of tumor-associated macrophages in human prostate cancer: Association with cancer progression
    • Shimura S, Yang G, Ebara S, Wheeler TM, Frolov A, Thompson TC. Reduced infiltration of tumor-associated macrophages in human prostate cancer: association with cancer progression. Cancer Res 2000; 60: 5857-61.
    • (2000) Cancer Res , vol.60 , pp. 5857-5861
    • Shimura, S.1    Yang, G.2    Ebara, S.3    Wheeler, T.M.4    Frolov, A.5    Thompson, T.C.6
  • 2
    • 12944332009 scopus 로고    scopus 로고
    • Prognostic factors in prostate cancer. College of American Pathologists Consensus Statement 1999
    • Bostwick DG, Grignon DJ, Hammond ME et al. Prognostic factors in prostate cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000; 124: 995-1000.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 995-1000
    • Bostwick, D.G.1    Grignon, D.J.2    Hammond, M.E.3
  • 4
    • 0031828159 scopus 로고    scopus 로고
    • The role of biopsy pathology, quantitative nuclear morphometry, and biomarkers in the preoperative prediction of prostate cancer staging and prognosis
    • Veltri RW, O'Dowd GJ, Orozco R, Miller MC. The role of biopsy pathology, quantitative nuclear morphometry, and biomarkers in the preoperative prediction of prostate cancer staging and prognosis. Semin Urol Oncol 1998; 16: 106-17.
    • (1998) Semin Urol Oncol , vol.16 , pp. 106-117
    • Veltri, R.W.1    O'Dowd, G.J.2    Orozco, R.3    Miller, M.C.4
  • 5
    • 0034768230 scopus 로고    scopus 로고
    • Pretreatment serum level of testosterone as a prognostic factor in Japanese men with hormonally treated stage D2 prostate cancer
    • Imamoto T, Suzuki H, Akakura K, et al. Pretreatment serum level of testosterone as a prognostic factor in Japanese men with hormonally treated stage D2 prostate cancer. Endocr J 2001; 48: 573-78.
    • (2001) Endocr J , vol.48 , pp. 573-578
    • Imamoto, T.1    Suzuki, H.2    Akakura, K.3
  • 6
    • 0030447040 scopus 로고    scopus 로고
    • Allelic losses at loci on chromosome 10 are associated with metastasis and progression of human prostate cancer
    • Komiya A, Suzuki H, Ueda T, et al. Allelic losses at loci on chromosome 10 are associated with metastasis and progression of human prostate cancer. Genes Chromosomes Cancer 1996; 17: 245-53.
    • (1996) Genes Chromosomes Cancer , vol.17 , pp. 245-253
    • Komiya, A.1    Suzuki, H.2    Ueda, T.3
  • 7
    • 0036219874 scopus 로고    scopus 로고
    • Mechanisms involved in the progression of androgen-independent prostate cancers: It is not only the cancer cell's fault
    • JT Arnoldl and J T Isaacs Mechanisms involved in the progression of androgen-independent prostate cancers: it is not only the cancer cell's fault. Endocrine-Related Cancer, 2002; 9: 61-73.
    • (2002) Endocrine-Related Cancer , vol.9 , pp. 61-73
    • Arnoldl, J.T.1    Isaacs, J.T.2
  • 8
    • 0031034478 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in carcinomas of the prostate: Do neuroendocrine serum markers reflect immunohistochemical findings?
    • Angelsen A, Syversen U, Haugen OA, Stridsberg M, Mjolnerod OK, Waldum HL. Neuroendocrine differentiation in carcinomas of the prostate: do neuroendocrine serum markers reflect immunohistochemical findings? Prostate 1997; 30: 1-6.
    • (1997) Prostate , vol.30 , pp. 1-6
    • Angelsen, A.1    Syversen, U.2    Haugen, O.A.3    Stridsberg, M.4    Mjolnerod, O.K.5    Waldum, H.L.6
  • 9
    • 0034213145 scopus 로고    scopus 로고
    • Circulating neuroendocrine markers in patients with prostate carcinoma
    • Berruti A, Dogliotti L, Mosca A, et al. Circulating neuroendocrine markers in patients with prostate carcinoma. Cancer 2000; 88: 2590-97.
    • (2000) Cancer , vol.88 , pp. 2590-2597
    • Berruti, A.1    Dogliotti, L.2    Mosca, A.3
  • 11
    • 0041857994 scopus 로고    scopus 로고
    • Pretreatment serum level of neuron specific enolase (NSE) as a prognostic factor in metastatic prostate cancer patients treated with endocrine therapy
    • discussion 314
    • Kamiya N, Akakura K, Suzuki H Isshiki S, Komiya A, Ueda T, Ito H. Pretreatment serum level of neuron specific enolase (NSE) as a prognostic factor in metastatic prostate cancer patients treated with endocrine therapy. Eur Urol 2003; 44: 309-14; discussion 314.
    • (2003) Eur Urol , vol.44 , pp. 309-314
    • Kamiya, N.1    Akakura, K.2    Suzuki, H.3    Isshiki, S.4    Komiya, A.5    Ueda, T.6    Ito, H.7
  • 12
    • 43049088451 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in stage D2 prostate cancers
    • Kamiya N, Suzuki H, Kawamura K et al. Neuroendocrine differentiation in stage D2 prostate cancers. Int. J. Urol. 2008; 15: 423-28.
    • (2008) Int. J. Urol , vol.15 , pp. 423-428
    • Kamiya, N.1    Suzuki, H.2    Kawamura, K.3
  • 13
    • 0036141890 scopus 로고    scopus 로고
    • Chromogranin a concentration as a serum marker to predict prognosis after endocrine therapy for prostate cancer
    • Isshiki S, Akakura K, Komiya A, Suzuki H, Kamiya N, Ito H. Chromogranin a concentration as a serum marker to predict prognosis after endocrine therapy for prostate cancer. J Urol 2002; 167: 512-5.
    • (2002) J Urol , vol.167 , pp. 512-515
    • Isshiki, S.1    Akakura, K.2    Komiya, A.3    Suzuki, H.4    Kamiya, N.5    Ito, H.6
  • 14
    • 9044235581 scopus 로고    scopus 로고
    • Plasma neuroendocrine markers in patients with benign prostatic hyperplasia and prostatic carcinoma
    • Cussenot O, Villette JM, Valeri A Cariou G, et al. Plasma neuroendocrine markers in patients with benign prostatic hyperplasia and prostatic carcinoma. J Urol 1996; 155: 1340-43.
    • (1996) J Urol , vol.155 , pp. 1340-1343
    • Cussenot, O.1    Villette, J.M.2    Valeri, A.3    Cariou, G.4
  • 15
    • 0035253571 scopus 로고    scopus 로고
    • Prognostic value of neuroendocrine serum markers and PSA in irradiated patients with pN0 localized prostate cancer
    • Lilleby W, Paus E, Skovlund E, Fossa SD. Prognostic value of neuroendocrine serum markers and PSA in irradiated patients with pN0 localized prostate cancer. Prostate 2001; 46: 126-33.
    • (2001) Prostate , vol.46 , pp. 126-133
    • Lilleby, W.1    Paus, E.2    Skovlund, E.3    Fossa, S.D.4
  • 16
    • 0028302956 scopus 로고
    • A more objective staging of advanced prostate cancer-routine recognition of malignant endocrine structures: The assessment of serum TPS, PSA, and NSE values
    • Tarle M, Frkovic-Grazio S, Kraljic I, Kovacic K. A more objective staging of advanced prostate cancer-routine recognition of malignant endocrine structures: the assessment of serum TPS, PSA, and NSE values. Prostate 1994; 24: 143-48.
    • (1994) Prostate , vol.24 , pp. 143-148
    • Tarle, M.1    Frkovic-Grazio, S.2    Kraljic, I.3    Kovacic, K.4
  • 17
    • 0026355799 scopus 로고
    • Elevated plasma chromogranin-A concentrations in prostatic carcinoma
    • Kadmon D, Thompson TC, Lynch GR, Scardino PT. Elevated plasma chromogranin-A concentrations in prostatic carcinoma. J Urol 1991; 146: 358-61.
    • (1991) J Urol , vol.146 , pp. 358-361
    • Kadmon, D.1    Thompson, T.C.2    Lynch, G.R.3    Scardino, P.T.4
  • 18
    • 26844437741 scopus 로고    scopus 로고
    • Evaluation and clinical value of neuroendocrine differentiation in human prostatic tumors
    • Cussenot O, Villette JM, Cochand-Priollet B, Berthon P. Evaluation and clinical value of neuroendocrine differentiation in human prostatic tumors. Prostate Suppl 1998; 8: 43-51.
    • (1998) Prostate Suppl , vol.8 , pp. 43-51
    • Cussenot, O.1    Villette, J.M.2    Cochand-Priollet, B.3    Berthon, P.4
  • 19
    • 0344457271 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostatic carcinoma
    • Abrahamsson PA. Neuroendocrine differentiation in prostatic carcinoma. Prostate 1999; 39: 135-48.
    • (1999) Prostate , vol.39 , pp. 135-148
    • Abrahamsson, P.A.1
  • 20
    • 0033370811 scopus 로고    scopus 로고
    • Neuroendocrine cells in tumour growth of the prostate
    • Abrahamsson PA. Neuroendocrine cells in tumour growth of the prostate. Endocr Relat Cancer 1999; 6: 503-19.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 503-519
    • Abrahamsson, P.A.1
  • 21
    • 0035167146 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostatic carcinoma: An update on recent developments
    • di Sant'Agnese P.A. Neuroendocrine differentiation in prostatic carcinoma: an update on recent developments. Ann of Oncol 2001; 12 (Suppl.2): S135-S140.
    • (2001) Ann of Oncol , vol.12 , Issue.SUPPL. 2
    • di Sant'Agnese, P.A.1
  • 22
    • 27644586339 scopus 로고    scopus 로고
    • Immunohistochemical and ultrastructural features of neuroendocrine differentiated carcinomas of the Prostate: An immunoelectron microscopic study
    • Hirano D, Jike T, Okada Y, et al. Immunohistochemical and ultrastructural features of neuroendocrine differentiated carcinomas of the Prostate: an immunoelectron microscopic study. Ultrastruct Pathol 2005; 29: 367-75.
    • (2005) Ultrastruct Pathol , vol.29 , pp. 367-375
    • Hirano, D.1    Jike, T.2    Okada, Y.3
  • 23
    • 0030947224 scopus 로고    scopus 로고
    • The prognostic value of neuroendocrine differentiation in adenocarcinoma of the prostate in relation to progression of disease after endocrine therapy
    • Krijnen JL, Bogdanowicz J, Seldenrijk CA, Mulder PG, van der Kwast TH. The prognostic value of neuroendocrine differentiation in adenocarcinoma of the prostate in relation to progression of disease after endocrine therapy. J Urol 1997; 158: 171-4.
    • (1997) J Urol , vol.158 , pp. 171-174
    • Krijnen, J.L.1    Bogdanowicz, J.2    Seldenrijk, C.A.3    Mulder, P.G.4    van der Kwast, T.H.5
  • 24
    • 0030443759 scopus 로고    scopus 로고
    • The expression and localization of β-nerve growth factor (β-NGF) in benign and malignant human prostate tissue: Relationship to neuroendocrine differentiation
    • Paul AB, Grant ES, Habib FK. The expression and localization of β-nerve growth factor (β-NGF) in benign and malignant human prostate tissue: relationship to neuroendocrine differentiation. Br J Cancer 1996; 74: 1990-96.
    • (1996) Br J Cancer , vol.74 , pp. 1990-1996
    • Paul, A.B.1    Grant, E.S.2    Habib, F.K.3
  • 25
    • 3343020830 scopus 로고    scopus 로고
    • Epidermal growth factor, neurotrophins and the metastatic cascade in prostate cancer
    • Montano X, Djamgoz MBA. Epidermal growth factor, neurotrophins and the metastatic cascade in prostate cancer. FEBS Lett 2004; 571: 1-8.
    • (2004) FEBS Lett , vol.571 , pp. 1-8
    • Montano, X.1    Djamgoz, M.B.A.2
  • 26
    • 0026757188 scopus 로고
    • Reduced expression of the low affinity nerve growth factor receptor in benign and malignant human prostate tissue and loss of expression in four human metastatic prostate tumor cell lines
    • Pflug BR, Onoda M, Lynch JH, Djakiew D. Reduced expression of the low affinity nerve growth factor receptor in benign and malignant human prostate tissue and loss of expression in four human metastatic prostate tumor cell lines. Cancer Res 1992; 52: 5403-6.
    • (1992) Cancer Res , vol.52 , pp. 5403-5406
    • Pflug, B.R.1    Onoda, M.2    Lynch, J.H.3    Djakiew, D.4
  • 27
    • 79955572744 scopus 로고    scopus 로고
    • Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis
    • Kang NJ, Shin SH, Lee HJ, Lee KW. Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis. Pharmacol & Therap 2011; 130: 310-24.
    • (2011) Pharmacol & Therap , vol.130 , pp. 310-324
    • Kang, N.J.1    Shin, S.H.2    Lee, H.J.3    Lee, K.W.4
  • 28
    • 84855969619 scopus 로고    scopus 로고
    • Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: Phenolic acids, monophenol, polyphenol, and their derivatives
    • Weng CJ, Yen GC. Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: Phenolic acids, monophenol, polyphenol, and their derivatives. Cancer Treat Rev 2012; 38: 76-87.
    • (2012) Cancer Treat Rev , vol.38 , pp. 76-87
    • Weng, C.J.1    Yen, G.C.2
  • 29
    • 0033788223 scopus 로고    scopus 로고
    • Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing
    • Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kader AA. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem 2000; 48: 4581-9.
    • (2000) J Agric Food Chem , vol.48 , pp. 4581-4589
    • Gil, M.I.1    Tomas-Barberan, F.A.2    Hess-Pierce, B.3    Holcroft, D.M.4    Kader, A.A.5
  • 30
    • 0034013311 scopus 로고    scopus 로고
    • Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: Studies in humans and in atherosclerotic apolipoprotein E-deficient mice
    • Aviram M, Dornfield L, Rosenblatt M, et al. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr 2000; 71: 1062-76.
    • (2000) Am J Clin Nutr , vol.71 , pp. 1062-1076
    • Aviram, M.1    Dornfield, L.2    Rosenblatt, M.3
  • 31
    • 0034900739 scopus 로고    scopus 로고
    • Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis
    • Kaplan M, Hayek T, Raz A, Coleman R, Dornfield L, Vaya J, Aviram M. Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J Nutr 2001; 131: 2082-9.
    • (2001) J Nutr , vol.131 , pp. 2082-2089
    • Kaplan, M.1    Hayek, T.2    Raz, A.3    Coleman, R.4    Dornfield, L.5    Vaya, J.6    Aviram, M.7
  • 32
    • 0036201937 scopus 로고    scopus 로고
    • Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer
    • Kim ND, Mehta R, Yu W, et al. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Res Treat 2002; 71: 203-17.
    • (2002) Breast Cancer Res Treat , vol.71 , pp. 203-217
    • Kim, N.D.1    Mehta, R.2    Yu, W.3
  • 33
    • 0038284925 scopus 로고    scopus 로고
    • Repeated oral administration of high doses of pomegranate ellagitannin punicalagin to rats for 37 days is not toxic
    • Cerda B, Ceron JJ, Tomas-Barberan FA, Espin JC. Repeated oral administration of high doses of pomegranate ellagitannin punicalagin to rats for 37 days is not toxic. J Agric Food Chem 2003; 51: 3493-501.
    • (2003) J Agric Food Chem , vol.51 , pp. 3493-3501
    • Cerda, B.1    Ceron, J.J.2    Tomas-Barberan, F.A.3    Espin, J.C.4
  • 34
    • 0037219635 scopus 로고    scopus 로고
    • Evaluation of the bioavailability and metabolism in the rat of punicalagin, an antioxidant polyphenol from pomegranate juice
    • Cerda B, Llorach R, Ceron JJ, Espin JC, Tomas-Barberan FA. Evaluation of the bioavailability and metabolism in the rat of punicalagin, an antioxidant polyphenol from pomegranate juice. Eur J Nutr 2003; 42: 18-28.
    • (2003) Eur J Nutr , vol.42 , pp. 18-28
    • Cerda, B.1    Llorach, R.2    Ceron, J.J.3    Espin, J.C.4    Tomas-Barberan, F.A.5
  • 35
    • 0032923360 scopus 로고    scopus 로고
    • p53/p21 (WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells
    • Narayanan BA, Geoffrey O, Willingham MC, Re GG, Nixon DW. p53/p21 (WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells. Cancer Lett 1999; 136: 215-21.
    • (1999) Cancer Lett , vol.136 , pp. 215-221
    • Narayanan, B.A.1    Geoffrey, O.2    Willingham, M.C.3    Re, G.G.4    Nixon, D.W.5
  • 36
    • 0032782963 scopus 로고    scopus 로고
    • Prevention of Nnitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice
    • Khanduja KL, Gandhi RK, Pathania V, Syanl N. Prevention of Nnitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice. Food Chem Toxicol 1999; 37: 313-8.
    • (1999) Food Chem Toxicol , vol.37 , pp. 313-318
    • Khanduja, K.L.1    Gandhi, R.K.2    Pathania, V.3    Syanl, N.4
  • 37
    • 0041709308 scopus 로고    scopus 로고
    • Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells
    • Mertens-Talcott SU, Talcott ST, Percival SS. Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells. J Nutr 2003; 133: 2669-74.
    • (2003) J Nutr , vol.133 , pp. 2669-2674
    • Mertens-Talcott, S.U.1    Talcott, S.T.2    Percival, S.S.3
  • 39
    • 20144381777 scopus 로고    scopus 로고
    • In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice
    • Seeram NP, Adams T, Henning SM, et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J of Nutr Biochem 2005; 16: 360-7.
    • (2005) J of Nutr Biochem , vol.16 , pp. 360-367
    • Seeram, N.P.1    Adams, T.2    Henning, S.M.3
  • 40
    • 34948873551 scopus 로고    scopus 로고
    • Pomegranate Ellagitannin-Derived Metabolites Inhibit Prostate Cancer Growth and Localize to the Mouse Prostate Gland
    • Seeram NP, Aronson WJ, Zhang Y, et al. Pomegranate Ellagitannin-Derived Metabolites Inhibit Prostate Cancer Growth and Localize to the Mouse Prostate Gland. J Agric Food Chem 2007; 55: 7732-7.
    • (2007) J Agric Food Chem , vol.55 , pp. 7732-7737
    • Seeram, N.P.1    Aronson, W.J.2    Zhang, Y.3
  • 41
    • 14844355240 scopus 로고    scopus 로고
    • Support Ellagic Acid Therapy in Patients with Hormone Refractory Prostate Cancer (HRPC) on Standard Chemotherapy Using Vinorelbine and Estramustine Phosphate
    • Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Support Ellagic Acid Therapy in Patients with Hormone Refractory Prostate Cancer (HRPC) on Standard Chemotherapy Using Vinorelbine and Estramustine Phosphate. Eur Urol 2005; 47: 449-55.
    • (2005) Eur Urol , vol.47 , pp. 449-455
    • Falsaperla, M.1    Morgia, G.2    Tartarone, A.3    Ardito, R.4    Romano, G.5
  • 42
    • 15244361547 scopus 로고    scopus 로고
    • Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel TM
    • Lansky EP, Harrison G, Froom P, Jiang WG. Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel TM. Invest New Drugs 2005; 23: 121-2.
    • (2005) Invest New Drugs , vol.23 , pp. 121-122
    • Lansky, E.P.1    Harrison, G.2    Froom, P.3    Jiang, W.G.4
  • 43
    • 38849088073 scopus 로고    scopus 로고
    • Ellagitannin-rich pomegranate extract inhibits angiogenesis in prostate cancer in vitro and in vivo
    • Sartippour M, Seeram NP, Rao JY, et al. Ellagitannin-rich pomegranate extract inhibits angiogenesis in prostate cancer in vitro and in vivo Int J Oncol 2008; 32: 475-80.
    • (2008) Int J Oncol , vol.32 , pp. 475-480
    • Sartippour, M.1    Seeram, N.P.2    Rao, J.Y.3
  • 44
    • 33947189936 scopus 로고    scopus 로고
    • Cytodifferentiation by retinoids, a novel therapeutic option in oncology: Rational combinations with other therapeutic agents
    • Garattini E, Gianni' M, Terao M. Cytodifferentiation by retinoids, a novel therapeutic option in oncology: rational combinations with other therapeutic agents. Vitam Horm. 2007; 75: 301-54.
    • (2007) Vitam Horm , vol.75 , pp. 301-354
    • Garattini, E.1    Gianni', M.2    Terao, M.3
  • 45
    • 10044258429 scopus 로고    scopus 로고
    • Differentiation of human melanoma cells induced by cyanidin-3-O-β-glucopyranoside
    • Serafino A, Sinibaldi-Vallebona P, Lazzarino G, et al. Differentiation of human melanoma cells induced by cyanidin-3-O-β-glucopyranoside. Faseb J 2004; 18: 1940-2.
    • (2004) Faseb J , vol.18 , pp. 1940-1942
    • Serafino, A.1    Sinibaldi-Vallebona, P.2    Lazzarino, G.3
  • 46
    • 80053211511 scopus 로고    scopus 로고
    • The DDAH/NOS pathway in human prostatic cancer cell lines: Antiangiogenic effect of L-NAME
    • Vanella L, Di Giacomo C, Acquaviva R, et al. The DDAH/NOS pathway in human prostatic cancer cell lines: antiangiogenic effect of L-NAME. Int J Oncol. 2011; 39: 1303-10.
    • (2011) Int J Oncol , vol.39 , pp. 1303-1310
    • Vanella, L.1    Di Giacomo, C.2    Acquaviva, R.3
  • 47
    • 0036740678 scopus 로고    scopus 로고
    • Nerve growth factor induces the re-expression of functional androgen receptors and p75NGFR in the androgen-insensitive prostate cancer cell line DU145
    • Sigala S, Tognazzi N, Rizzetti MC, et al. Nerve growth factor induces the re-expression of functional androgen receptors and p75NGFR in the androgen-insensitive prostate cancer cell line DU145. Eur J Endocrinol 2002; 147: 407-15.
    • (2002) Eur J Endocrinol , vol.147 , pp. 407-415
    • Sigala, S.1    Tognazzi, N.2    Rizzetti, M.C.3
  • 48
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3 Kinase Akt pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3 Kinase Akt pathway in human cancer. Nat Rev Cancer 2002; 2: 489-501.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 49
    • 0346849777 scopus 로고    scopus 로고
    • Effects of age on DNA doublestrandbreaks and apoptosis in human sperm
    • Singh NP, Muller CH, Berger RE. Effects of age on DNA doublestrandbreaks and apoptosis in human sperm. Fertil Steril 2003; 80: 1420-30.
    • (2003) Fertil Steril , vol.80 , pp. 1420-1430
    • Singh, N.P.1    Muller, C.H.2    Berger, R.E.3
  • 51
    • 30544440563 scopus 로고    scopus 로고
    • Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells
    • Russo A, Cardile V, Lombardo L, Vanella L, Acquaviva R. Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells. J Nutr Biochem 2006; 17: 103-8.
    • (2006) J Nutr Biochem , vol.17 , pp. 103-108
    • Russo, A.1    Cardile, V.2    Lombardo, L.3    Vanella, L.4    Acquaviva, R.5
  • 53
    • 0031595996 scopus 로고    scopus 로고
    • Expression of p75NTR in a human prostate epithelial tumor cell line reduces nerve growth factor induced cell growth by activation of programmed cell death
    • Pflug BR, Djakiew D. Expression of p75NTR in a human prostate epithelial tumor cell line reduces nerve growth factor induced cell growth by activation of programmed cell death. Mol Carcinogen 1998; 23: 106-14.
    • (1998) Mol Carcinogen , vol.23 , pp. 106-114
    • Pflug, B.R.1    Djakiew, D.2
  • 54
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • Nevins JR. The Rb/E2F pathway and cancer. Hum Mol Genet. 2001; 10: 699-703.
    • (2001) Hum Mol Genet , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 55
    • 0034326839 scopus 로고    scopus 로고
    • Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression
    • Bowen C, Bubendorf L, Voeller HJ, et al. Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression, Cancer Res 2000; 60: 6111-15.
    • (2000) Cancer Res , vol.60 , pp. 6111-6115
    • Bowen, C.1    Bubendorf, L.2    Voeller, H.J.3
  • 56
    • 0034327299 scopus 로고    scopus 로고
    • Sex hormoneinduced carcinogenesis in Rb-deficient prostate tissue
    • Wang Y, Hayward SW, Donjacour AA, et al. Sex hormoneinduced carcinogenesis in Rb-deficient prostate tissue. Cancer Res 2000; 60: 6008-17.
    • (2000) Cancer Res , vol.60 , pp. 6008-6017
    • Wang, Y.1    Hayward, S.W.2    Donjacour, A.A.3
  • 57
    • 79251473704 scopus 로고    scopus 로고
    • Disulfiram Is a DNA Demethylating Agent and Inhibits Prostate Cancer Cell Growth
    • Lin J, Haffner MC, Zhang Y, et al. Disulfiram Is a DNA Demethylating Agent and Inhibits Prostate Cancer Cell Growth. Prostate 2011; 71: 333-43.
    • (2011) Prostate , vol.71 , pp. 333-343
    • Lin, J.1    Haffner, M.C.2    Zhang, Y.3
  • 58
    • 18144419362 scopus 로고    scopus 로고
    • Regulation of DNA Methyltransferase 1 by the pRb/E2F1 Pathway
    • McCabe MT, Davis JN and Day ML. Regulation of DNA Methyltransferase 1 by the pRb/E2F1 Pathway. Cancer Res 2005; 65: 3624-32.
    • (2005) Cancer Res , vol.65 , pp. 3624-3632
    • McCabe, M.T.1    Davis, J.N.2    Day, M.L.3
  • 59
    • 84155172882 scopus 로고    scopus 로고
    • The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells
    • Ruiz-Magaña MJ, Rodríguez-Vargas JM, Morales JC, Saldivia MA, Schulze-Osthoff K, Ruiz-Ruiz C. The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells. Int J Cancer 2012; 130: 1195-207.
    • (2012) Int J Cancer , vol.130 , pp. 1195-1207
    • Ruiz-Magaña, M.J.1    Rodríguez-Vargas, J.M.2    Morales, J.C.3    Saldivia, M.A.4    Schulze-Osthoff, K.5    Ruiz-Ruiz, C.6
  • 60
    • 0033145943 scopus 로고    scopus 로고
    • Antioxidant actions of plant foods. Use of oxidative DNA damage as a tool for studying antioxidant efficacy
    • Aruoma OI. Antioxidant actions of plant foods. Use of oxidative DNA damage as a tool for studying antioxidant efficacy. Free Radic Res 1999; 30: 419-27.
    • (1999) Free Radic Res , vol.30 , pp. 419-427
    • Aruoma, O.I.1
  • 61
    • 0029161958 scopus 로고
    • The head involution defective gene of Drosophila melanogaster functions in programmed cell death
    • Grether ME, Abrams JM, Agapite J, White K, Steller H. The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev 1995; 9: 1694-708.
    • (1995) Genes Dev , vol.9 , pp. 1694-1708
    • Grether, M.E.1    Abrams, J.M.2    Agapite, J.3    White, K.4    Steller, H.5
  • 62
    • 0037279198 scopus 로고    scopus 로고
    • p27KIP1 phosphorylation by PKB/Akt leads to poor breast cancer prognosis
    • Clarke RB. p27KIP1 phosphorylation by PKB/Akt leads to poor breast cancer prognosis. Breast Cancer Res 2003; 5: 162-3.
    • (2003) Breast Cancer Res , vol.5 , pp. 162-163
    • Clarke, R.B.1
  • 63
    • 0037352170 scopus 로고    scopus 로고
    • Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
    • Chang F, Lee JT, Navolanic PM, et al. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 2003; 17: 590-603.
    • (2003) Leukemia , vol.17 , pp. 590-603
    • Chang, F.1    Lee, J.T.2    Navolanic, P.M.3
  • 64
    • 0035992417 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway
    • Li Y, Sarkar FH. Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clin Cancer Res 2002; 8: 2369-77.
    • (2002) Clin Cancer Res , vol.8 , pp. 2369-2377
    • Li, Y.1    Sarkar, F.H.2
  • 65
    • 0036554871 scopus 로고    scopus 로고
    • Akt inactivation is a key event indole-3-carbinol-induced apoptosis in PC-3 cells
    • Chinni SR, Sarkar FH. Akt inactivation is a key event indole-3-carbinol-induced apoptosis in PC-3 cells. Clin Cancer Res 2002; 8: 1228-36.
    • (2002) Clin Cancer Res , vol.8 , pp. 1228-1236
    • Chinni, S.R.1    Sarkar, F.H.2
  • 66
    • 33644840279 scopus 로고    scopus 로고
    • Diosgenin inhibits osteoclastogenesis, invasion, and proliferation throught he downregulation of Akt, IkappaB kinase activation and NF-kappaB-regulated gene expression
    • Shishodia S, Aggarwal BB. Diosgenin inhibits osteoclastogenesis, invasion, and proliferation throught he downregulation of Akt, IkappaB kinase activation and NF-kappaB-regulated gene expression. Oncogene 2006; 25: 1463-73.
    • (2006) Oncogene , vol.25 , pp. 1463-1473
    • Shishodia, S.1    Aggarwal, B.B.2
  • 67
    • 30044446136 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) downregulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation
    • Aggarwal S, Ichikawa H, Takada Y, Sandur SK, ShishodiaS, Aggarwal BB. Curcumin (diferuloylmethane) downregulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation. Mol Pharmacol 2006; 69: 195-206.
    • (2006) Mol Pharmacol , vol.69 , pp. 195-206
    • Aggarwal, S.1    Ichikawa, H.2    Takada, Y.3    Sandur, S.K.4    Shishodia, S.5    Aggarwal, B.B.6
  • 68
    • 0042338791 scopus 로고    scopus 로고
    • Green tea catechins inhibit VEGF-induced angiogenesis in vitro through suppression of VEcadherin phosphorylation and inactivation of Akt molecule
    • Tang FY, Nguyen N, Meydani M. Green tea catechins inhibit VEGF-induced angiogenesis in vitro through suppression of VEcadherin phosphorylation and inactivation of Akt molecule. Int J Cancer 2003; 106: 871-8.
    • (2003) Int J Cancer , vol.106 , pp. 871-878
    • Tang, F.Y.1    Nguyen, N.2    Meydani, M.3
  • 69
    • 31544436674 scopus 로고    scopus 로고
    • Black raspberry extracts inhibit benzo(a)pyrenediol-epoxide-induced activator protein 1 activation and VEGF transcription by targeting the phosphotidylinositol 3-kinase/Akt pathway
    • Huang C, Li J, Song L, et al. Black raspberry extracts inhibit benzo(a)pyrenediol-epoxide-induced activator protein 1 activation and VEGF transcription by targeting the phosphotidylinositol 3-kinase/Akt pathway. Cancer Res 2006; 66: 581-7.
    • (2006) Cancer Res , vol.66 , pp. 581-587
    • Huang, C.1    Li, J.2    Song, L.3
  • 70
    • 0037404397 scopus 로고    scopus 로고
    • Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells
    • Chaudhary LR, Hruska KA. Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells. J Cell Biochem 2003; 89: 1-5.
    • (2003) J Cell Biochem , vol.89 , pp. 1-5
    • Chaudhary, L.R.1    Hruska, K.A.2
  • 72
    • 23644441924 scopus 로고    scopus 로고
    • Enhancement of radiationinduced oxidative stress and cytotoxicity in tumor cells by ellagic acid
    • Bhosle SM, Huilgol NG, Mishra KP. Enhancement of radiationinduced oxidative stress and cytotoxicity in tumor cells by ellagic acid. Clin Chim Acta 2005; 359: 89-100.
    • (2005) Clin Chim Acta , vol.359 , pp. 89-100
    • Bhosle, S.M.1    Huilgol, N.G.2    Mishra, K.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.