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Volumn 542, Issue , 2013, Pages 87-91

Butein inhibits NF-κB activation and reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats

Author keywords

Apoptosis; Butein; IKK inhibitors; Inflammatory response; Neuroprotection; NF B; Spinal cord injury

Indexed keywords

BUTEIN; CASPASE 3; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOPEROXIDASE; SYNAPTOTAGMIN I;

EID: 84876727874     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.03.004     Document Type: Article
Times cited : (29)

References (43)
  • 1
    • 0037439232 scopus 로고    scopus 로고
    • Peroxynitrite generated in the rat spinal cord induces apoptotic cell death and activates caspase-3
    • Bao F., Liu D. Peroxynitrite generated in the rat spinal cord induces apoptotic cell death and activates caspase-3. Neuroscience 2003, 116:59-70.
    • (2003) Neuroscience , vol.116 , pp. 59-70
    • Bao, F.1    Liu, D.2
  • 2
    • 2942657443 scopus 로고    scopus 로고
    • Hydroxyl radicals generated in the rat spinal cord at the level produced by impact injury induce cell death by necrosis and apoptosis: protection by a metalloporphyrin
    • Bao F., Liu D. Hydroxyl radicals generated in the rat spinal cord at the level produced by impact injury induce cell death by necrosis and apoptosis: protection by a metalloporphyrin. Neuroscience 2004, 126:285-295.
    • (2004) Neuroscience , vol.126 , pp. 285-295
    • Bao, F.1    Liu, D.2
  • 3
    • 9644259008 scopus 로고    scopus 로고
    • Inflammation and apoptosis: linked therapeutic targets in spinal cord injury
    • Beattie M.S. Inflammation and apoptosis: linked therapeutic targets in spinal cord injury. Trends Mol. Med. 2004, 10:580-583.
    • (2004) Trends Mol. Med. , vol.10 , pp. 580-583
    • Beattie, M.S.1
  • 4
    • 77249125330 scopus 로고    scopus 로고
    • Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment
    • Beck K.D., Nguyen H.X., Galvan M.D., Salazar D.L., Woodruff T.M., Anderson A.J. Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain 2010, 133:433-447.
    • (2010) Brain , vol.133 , pp. 433-447
    • Beck, K.D.1    Nguyen, H.X.2    Galvan, M.D.3    Salazar, D.L.4    Woodruff, T.M.5    Anderson, A.J.6
  • 5
    • 0034589409 scopus 로고    scopus 로고
    • Spinal cord injury-induced inflammation: a dual-edged sword
    • Bethea J.R. Spinal cord injury-induced inflammation: a dual-edged sword. Prog. Brain Res. 2000, 128:33-42.
    • (2000) Prog. Brain Res. , vol.128 , pp. 33-42
    • Bethea, J.R.1
  • 7
    • 22344431751 scopus 로고    scopus 로고
    • Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
    • Brambilla R., Bracchi-Ricard V., Hu W.H., Frydel B., Bramwell A., Karmally S., Green E.J., Bethea J.R. Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury. J. Exp. Med. 2005, 202:145-156.
    • (2005) J. Exp. Med. , vol.202 , pp. 145-156
    • Brambilla, R.1    Bracchi-Ricard, V.2    Hu, W.H.3    Frydel, B.4    Bramwell, A.5    Karmally, S.6    Green, E.J.7    Bethea, J.R.8
  • 8
    • 35648982325 scopus 로고    scopus 로고
    • Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury
    • Byrnes K.R., Stoica B.A., Fricke S., Di Giovanni S., Faden A.I. Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury. Brain 2007, 130:2977-2992.
    • (2007) Brain , vol.130 , pp. 2977-2992
    • Byrnes, K.R.1    Stoica, B.A.2    Fricke, S.3    Di Giovanni, S.4    Faden, A.I.5
  • 9
    • 0034128623 scopus 로고    scopus 로고
    • Posttraumatic hypothermia reduces polymorphonuclear leukocyte accumulation following spinal cord injury in rats
    • Chatzipanteli K., Yanagawa Y., Marcillo A.E., Kraydieh S., Yezierski R.P., Dietrich W.D. Posttraumatic hypothermia reduces polymorphonuclear leukocyte accumulation following spinal cord injury in rats. J. Neurotrauma 2000, 17:321-332.
    • (2000) J. Neurotrauma , vol.17 , pp. 321-332
    • Chatzipanteli, K.1    Yanagawa, Y.2    Marcillo, A.E.3    Kraydieh, S.4    Yezierski, R.P.5    Dietrich, W.D.6
  • 10
    • 77957017047 scopus 로고    scopus 로고
    • Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-kappa B activation in breast and pancreatic tumor cells
    • Chua A.W., Hay H.S., Rajendran P., Shanmugam M.K., Li F., Bist P., Koay E.S., Lim L.H., Kumar A.P., Sethi G. Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-kappa B activation in breast and pancreatic tumor cells. Biochem. Pharmacol. 2010, 80:1553-1562.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1553-1562
    • Chua, A.W.1    Hay, H.S.2    Rajendran, P.3    Shanmugam, M.K.4    Li, F.5    Bist, P.6    Koay, E.S.7    Lim, L.H.8    Kumar, A.P.9    Sethi, G.10
  • 11
    • 84860132077 scopus 로고    scopus 로고
    • Neuroprotective and anti-inflammatory effects of flavonoids isolated from Rhus verniciflua in neuronal HT22 and microglial BV2 cell lines
    • Cho N., Choi J.H., Yang H., Jeong E.J., Lee K.Y., Kim Y.C., Sung S.H. Neuroprotective and anti-inflammatory effects of flavonoids isolated from Rhus verniciflua in neuronal HT22 and microglial BV2 cell lines. Food Chem. Toxicol. 2012, 50:1940-1945.
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 1940-1945
    • Cho, N.1    Choi, J.H.2    Yang, H.3    Jeong, E.J.4    Lee, K.Y.5    Kim, Y.C.6    Sung, S.H.7
  • 12
    • 0345095416 scopus 로고    scopus 로고
    • Role of inflammation in the secondary injury following experimental spinal cord trauma
    • Conti A., Cardali S., Genovese T., Di Paola R., La Rosa G. Role of inflammation in the secondary injury following experimental spinal cord trauma. J. Neurosurg. Sci. 2003, 47:89-94.
    • (2003) J. Neurosurg. Sci. , vol.47 , pp. 89-94
    • Conti, A.1    Cardali, S.2    Genovese, T.3    Di Paola, R.4    La Rosa, G.5
  • 15
    • 21344461953 scopus 로고    scopus 로고
    • Current status of clinical trials for acute spinal cord injury
    • Fehlings M.G., Baptiste D.C. Current status of clinical trials for acute spinal cord injury. Injury 2005, 36(Suppl. 2):B113-B122.
    • (2005) Injury , vol.36 , Issue.SUPPL. 2
    • Fehlings, M.G.1    Baptiste, D.C.2
  • 16
    • 0035074297 scopus 로고    scopus 로고
    • Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion
    • Grossman S.D., Rosenberg L.J., Wrathall J.R. Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion. Exp. Neurol. 2001, 168:273-282.
    • (2001) Exp. Neurol. , vol.168 , pp. 273-282
    • Grossman, S.D.1    Rosenberg, L.J.2    Wrathall, J.R.3
  • 17
    • 33646577436 scopus 로고    scopus 로고
    • Degenerative and spontaneous regenerative processes after spinal cord injury
    • Hagg T., Oudega M. Degenerative and spontaneous regenerative processes after spinal cord injury. J. Neurotrauma 2006, 23:264-280.
    • (2006) J. Neurotrauma , vol.23 , pp. 264-280
    • Hagg, T.1    Oudega, M.2
  • 18
    • 17444392322 scopus 로고    scopus 로고
    • Neuroprotection and acute spinal cord injury: a reappraisal
    • Hall E.D., Springer J.E. Neuroprotection and acute spinal cord injury: a reappraisal. NeuroRx 2004, 1:80-100.
    • (2004) NeuroRx , vol.1 , pp. 80-100
    • Hall, E.D.1    Springer, J.E.2
  • 19
    • 84863089926 scopus 로고    scopus 로고
    • Targeting IKK/NF-kappaB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats
    • Han X., Lu M., Wang S., Lv D.C. Targeting IKK/NF-kappaB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats. Neurosci. Lett. 2012, 511:28-32.
    • (2012) Neurosci. Lett. , vol.511 , pp. 28-32
    • Han, X.1    Lu, M.2    Wang, S.3    Lv, D.C.4
  • 20
    • 80053201732 scopus 로고    scopus 로고
    • BMS-345541 inhibited nuclear factor kappa B expression and improved locomotor function recovery in rats after acute spinal cord injury
    • Han X., Wang S.Y., Zhang Z., Lü D.C., Liu H.R. BMS-345541 inhibited nuclear factor kappa B expression and improved locomotor function recovery in rats after acute spinal cord injury. Neural. Regen. Res. 2011, 6:1775-1779.
    • (2011) Neural. Regen. Res. , vol.6 , pp. 1775-1779
    • Han, X.1    Wang, S.Y.2    Zhang, Z.3    Lü, D.C.4    Liu, H.R.5
  • 22
    • 16244378048 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappaB signaling pathway by interleukin-1 after hypoxia/ischemia in neonatal rat hippocampus and cortex
    • Hu X., Nesic-Taylor O., Qiu J., Rea H.C., Fabian R., Rassin D.K., Perez-Polo J.R. Activation of nuclear factor-kappaB signaling pathway by interleukin-1 after hypoxia/ischemia in neonatal rat hippocampus and cortex. J. Neurochem. 2005, 93:26-37.
    • (2005) J. Neurochem. , vol.93 , pp. 26-37
    • Hu, X.1    Nesic-Taylor, O.2    Qiu, J.3    Rea, H.C.4    Fabian, R.5    Rassin, D.K.6    Perez-Polo, J.R.7
  • 23
    • 0032217268 scopus 로고    scopus 로고
    • The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappa B inactivation
    • Huxford T., Huang D.B., Malek S., Ghosh G. The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappa B inactivation. Cell 1998, 95:759-770.
    • (1998) Cell , vol.95 , pp. 759-770
    • Huxford, T.1    Huang, D.B.2    Malek, S.3    Ghosh, G.4
  • 25
    • 29744458521 scopus 로고    scopus 로고
    • Early effects of modulating nuclear factor-kappaB activation on traumatic spinal cord injury in rats
    • Jimenez-Garza O., Camacho J., Ibarra A., Martinez A., Guizar-Sahagun G. Early effects of modulating nuclear factor-kappaB activation on traumatic spinal cord injury in rats. Ann. N.Y. Acad. Sci. 2005, 1053:148-150.
    • (2005) Ann. N.Y. Acad. Sci. , vol.1053 , pp. 148-150
    • Jimenez-Garza, O.1    Camacho, J.2    Ibarra, A.3    Martinez, A.4    Guizar-Sahagun, G.5
  • 26
    • 2142699971 scopus 로고    scopus 로고
    • Hypotensive effect of butein via the inhibition of angiotensin converting enzyme
    • September 03
    • Kang D.G., Kim Y.C., Sohn E.J., Lee Y.M., Lee A.S., Yin M.H., Lee H.S. Hypotensive effect of butein via the inhibition of angiotensin converting enzyme. Biol. Pharm. Bull. 2003, 26:1345-1347. September 03.
    • (2003) Biol. Pharm. Bull. , vol.26 , pp. 1345-1347
    • Kang, D.G.1    Kim, Y.C.2    Sohn, E.J.3    Lee, Y.M.4    Lee, A.S.5    Yin, M.H.6    Lee, H.S.7
  • 27
    • 4444273842 scopus 로고    scopus 로고
    • Butein ameliorates renal concentrating ability in cisplatin-induced acute renal failure in rats
    • Kang D.G., Kim Y.C., Sohn E.J., Lee Y.M., Lee A.S., Yin M.H., Lee H.S. Butein ameliorates renal concentrating ability in cisplatin-induced acute renal failure in rats. Biol. Pharm. Bull. 2004, 27:366-370.
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 366-370
    • Kang, D.G.1    Kim, Y.C.2    Sohn, E.J.3    Lee, Y.M.4    Lee, A.S.5    Yin, M.H.6    Lee, H.S.7
  • 28
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappa B system: a treasure trove for drug development
    • Karin M., Yamamoto Y., Wang Q.M. The IKK NF-kappa B system: a treasure trove for drug development. Nat. Rev. Drug Discov. 2004, 3:17-26.
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 30
    • 3342967871 scopus 로고    scopus 로고
    • Pathophysiology and pharmacologic treatment of acute spinal cord injury
    • Kwon B.K., Tetzlaff W., Grauer J.N., Beiner J., Vaccaro A.R. Pathophysiology and pharmacologic treatment of acute spinal cord injury. J. Spine 2004, 4:451-464.
    • (2004) J. Spine , vol.4 , pp. 451-464
    • Kwon, B.K.1    Tetzlaff, W.2    Grauer, J.N.3    Beiner, J.4    Vaccaro, A.R.5
  • 31
    • 54049114674 scopus 로고    scopus 로고
    • The IKK-NF-kappaB pathway: a source for novel molecular drug targets in pain therapy
    • Niederberger E., Geisslinger G. The IKK-NF-kappaB pathway: a source for novel molecular drug targets in pain therapy. J. FASEB 2008, 22:3432-3442.
    • (2008) J. FASEB , vol.22 , pp. 3432-3442
    • Niederberger, E.1    Geisslinger, G.2
  • 32
    • 34547125342 scopus 로고    scopus 로고
    • Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue
    • Pandey M.K., Sandur S.K., Sung B., Sethi G., Kunnumakkara A.B., Aggarwal B.B. Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue. J. Biol. Chem. 2007, 282:17340-17350.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17340-17350
    • Pandey, M.K.1    Sandur, S.K.2    Sung, B.3    Sethi, G.4    Kunnumakkara, A.B.5    Aggarwal, B.B.6
  • 36
    • 63849340879 scopus 로고    scopus 로고
    • Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon
    • Rowland J.W., Hawryluk G.W., Kwon B., Fehlings M.G. Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon. Neurosurg. Focus 2008, 25:E2.
    • (2008) Neurosurg. Focus , vol.25
    • Rowland, J.W.1    Hawryluk, G.W.2    Kwon, B.3    Fehlings, M.G.4
  • 38
    • 27844597182 scopus 로고    scopus 로고
    • Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats
    • Sribnick E.A., Wingrave J.M., Matzelle D.D., Wilford G.G., Ray S.K., Banik N.L. Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats. J. Neurosci. Res. 2005, 82:283-293.
    • (2005) J. Neurosci. Res. , vol.82 , pp. 283-293
    • Sribnick, E.A.1    Wingrave, J.M.2    Matzelle, D.D.3    Wilford, G.G.4    Ray, S.K.5    Banik, N.L.6
  • 39
    • 0026326449 scopus 로고
    • Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms
    • Tator C.H., Fehlings M.G. Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J. Neurosurg. 1991, 75:15-26.
    • (1991) J. Neurosurg. , vol.75 , pp. 15-26
    • Tator, C.H.1    Fehlings, M.G.2
  • 40
    • 0030612215 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders: potential for therapy by modifying gene transcription
    • Tatton W.G., Chalmers-Redman R.M., Ju W.Y., Wadia J., Tatton N.A. Apoptosis in neurodegenerative disorders: potential for therapy by modifying gene transcription. J. Neural Transm. Suppl. 1997, 49:245-268.
    • (1997) J. Neural Transm. Suppl. , vol.49 , pp. 245-268
    • Tatton, W.G.1    Chalmers-Redman, R.M.2    Ju, W.Y.3    Wadia, J.4    Tatton, N.A.5
  • 41
    • 33845210126 scopus 로고    scopus 로고
    • Inflammation Spinal Cord Injury: Infiltrating Leukocytes as Determinants of Injury and Repair Processes
    • Trivedi A., Olivas A.D., Noble-Haeusslein L.J., Inflammation Spinal Cord Injury: Infiltrating Leukocytes as Determinants of Injury and Repair Processes. Clin. Neurosci. Res. 2006, 6:283-292.
    • (2006) Clin. Neurosci. Res. , vol.6 , pp. 283-292
    • Trivedi, A.1    Olivas, A.D.2    Noble-Haeusslein, L.J.3
  • 42
    • 0032584936 scopus 로고    scopus 로고
    • Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats
    • Xu J., Fan G., Chen S., Wu Y., Xu X.M., Hsu C.Y. Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats. Brain Res. Mol. Brain Res. 1998, 59:135-142.
    • (1998) Brain Res. Mol. Brain Res. , vol.59 , pp. 135-142
    • Xu, J.1    Fan, G.2    Chen, S.3    Wu, Y.4    Xu, X.M.5    Hsu, C.Y.6
  • 43
    • 79952104482 scopus 로고    scopus 로고
    • The role of chalcones in suppression of NF-kappaB-mediated inflammation and cancer
    • Yadav V.R., Prasad S., Sung B., Aggarwal B.B. The role of chalcones in suppression of NF-kappaB-mediated inflammation and cancer. Int. Immunopharmacol. 2011, 11:295-309.
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 295-309
    • Yadav, V.R.1    Prasad, S.2    Sung, B.3    Aggarwal, B.B.4


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