Mitochondrial and liver oxidative stress alterations induced by N-butyl-N-(4-hydroxybutyl)nitrosamine: Relevance for hepatotoxicity

Journal of Applied Toxicology

Volumn 33, Issue 6, 2013, Pages 434-443

  Oliveira, Maria M ^a   Teixeira, José C ^b   Vasconcelos Nóbrega, Cármen ^c   Felix, Luis M ^b   Sardão, Vilma A ^d   Colaço, Aura A ^b   Oliveira, Paula A ^b   Peixoto, Francisco P ^b  

^a UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^c POLYTECHNIC INSTITUTE OF VISEU   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Bioenergetics; Hydrogen peroxide; Mice; Mitochondria; Mitochondrial permeability transition pore; N butyl N (4 hydroxybutyl)nitrosamine; Oxidative stress; Protein expression

Indexed keywords

DRINKING WATER; HYDROGEN PEROXIDE; MALIC ACID; MITOCHONDRIAL COMPLEX IV; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRIAL PROTEIN; N BUTYL N (4 HYDROXYBUTYL)NITROSAMINE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENERGY; CONTROLLED STUDY; ELECTRIC POTENTIAL; LIPID PEROXIDATION; LIVER METABOLISM; LIVER TOXICITY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; BLOTTING, WESTERN; BUTYLHYDROXYBUTYLNITROSAMINE; CALCIUM; DRINKING; DRUG-INDUCED LIVER INJURY; EATING; ENERGY METABOLISM; GLUTATHIONE; GROWTH; HYDROGEN PEROXIDE; LIPID PEROXIDATION; LIVER; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED ICR; MITOCHONDRIA, LIVER; MITOCHONDRIAL DISEASES; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PERMEABILITY; SUPEROXIDE DISMUTASE;

MUS;

EID: 84876712347     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1763     Document Type: Article

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