-
1
-
-
84859956031
-
Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism
-
Quarles L.D. Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism. Nat Rev Endocrinol 2012, 8:276-286.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 276-286
-
-
Quarles, L.D.1
-
2
-
-
0037462746
-
Human fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production
-
Saito H., Kusano K., Kinosaki M., et al. Human fibroblast growth factor-23 mutants suppress Na+-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production. J Biol Chem 2003, 278:2206-2211.
-
(2003)
J Biol Chem
, vol.278
, pp. 2206-2211
-
-
Saito, H.1
Kusano, K.2
Kinosaki, M.3
-
3
-
-
0034805353
-
FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate
-
Bowe A.E., Finnegan R., Jan de Beur S.M., et al. FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate. Biochem Biophys Res Commun 2001, 284:977-981.
-
(2001)
Biochem Biophys Res Commun
, vol.284
, pp. 977-981
-
-
Bowe, A.E.1
Finnegan, R.2
Jan de Beur, S.M.3
-
4
-
-
33646367420
-
Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D
-
Liu S., Tang W., Zhou J., et al. Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 2006, 17:1305-1315.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1305-1315
-
-
Liu, S.1
Tang, W.2
Zhou, J.3
-
5
-
-
36849017126
-
The parathyroid is a target organ for FGF23 in rats
-
Ben-Dov I.Z., Galitzer H., Lavi-Moshayoff V., et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007, 117:4003-4008.
-
(2007)
J Clin Invest
, vol.117
, pp. 4003-4008
-
-
Ben-Dov, I.Z.1
Galitzer, H.2
Lavi-Moshayoff, V.3
-
6
-
-
78049463249
-
Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease
-
Hasegawa H., Nagano N., Urakawa I., et al. Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease. Kidney Int 2010, 78:975-980.
-
(2010)
Kidney Int
, vol.78
, pp. 975-980
-
-
Hasegawa, H.1
Nagano, N.2
Urakawa, I.3
-
7
-
-
84863550146
-
FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality
-
Shalhoub V., Shatzen E.M., Ward S.C., et al. FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality. J Clin Invest 2012, 122:2543-2553.
-
(2012)
J Clin Invest
, vol.122
, pp. 2543-2553
-
-
Shalhoub, V.1
Shatzen, E.M.2
Ward, S.C.3
-
8
-
-
79961052017
-
Lanthanum carbonate reduces FGF23 in chronic kidney disease Stage 3 patients
-
Gonzalez-Parra E., Gonzalez-Casaus M.L., Galan A., et al. Lanthanum carbonate reduces FGF23 in chronic kidney disease Stage 3 patients. Nephrol Dial Transplant 2011, 26:2567-2571.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 2567-2571
-
-
Gonzalez-Parra, E.1
Gonzalez-Casaus, M.L.2
Galan, A.3
-
9
-
-
79951895648
-
Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease
-
Moe S.M., Zidehsarai M.P., Chambers M.A., et al. Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease. Clin J Am Soc Nephrol 2011, 6:257-264.
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 257-264
-
-
Moe, S.M.1
Zidehsarai, M.P.2
Chambers, M.A.3
-
10
-
-
77749334660
-
Early control of PTH and FGF23 in normophosphatemic CKD patients: a new target in CKD-MBD therapy?
-
Oliveira R.B., Cancela A.L., Graciolli F.G., et al. Early control of PTH and FGF23 in normophosphatemic CKD patients: a new target in CKD-MBD therapy?. Clin J Am Soc Nephrol 2010, 5:286-291.
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, pp. 286-291
-
-
Oliveira, R.B.1
Cancela, A.L.2
Graciolli, F.G.3
-
11
-
-
0032567647
-
Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein
-
Matsumura Y., Aizawa H., Shiraki-Iida T., Nagai R., Kuro-o M., Nabeshima Y. Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein. Biochem Biophys Res Commun 1998, 242:626-630.
-
(1998)
Biochem Biophys Res Commun
, vol.242
, pp. 626-630
-
-
Matsumura, Y.1
Aizawa, H.2
Shiraki-Iida, T.3
Nagai, R.4
Kuro-o, M.5
Nabeshima, Y.6
-
13
-
-
77956642900
-
Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule
-
Hu M.C., Shi M., Zhang J., et al. Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J 2010, 24:3438-3450.
-
(2010)
FASEB J
, vol.24
, pp. 3438-3450
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
-
14
-
-
0032575483
-
Downregulation of the Klotho gene in the kidney under sustained circulatory stress in rats
-
Aizawa H., Saito Y., Nakamura T., et al. Downregulation of the Klotho gene in the kidney under sustained circulatory stress in rats. Biochem Biophys Res Commun 1998, 249:865-871.
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 865-871
-
-
Aizawa, H.1
Saito, Y.2
Nakamura, T.3
-
15
-
-
78649642147
-
Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective
-
Hu M.C., Shi M., Zhang J., Quinones H., Kuro-o M., Moe O.W. Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective. Kidney Int 2010, 78:1240-1251.
-
(2010)
Kidney Int
, vol.78
, pp. 1240-1251
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
Quinones, H.4
Kuro-o, M.5
Moe, O.W.6
-
16
-
-
84861168067
-
Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis
-
Sugiura H., Yoshida T., Shiohira S., et al. Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis. Am J Physiol Renal Physiol 2012, 302:F1252-F1264.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
-
-
Sugiura, H.1
Yoshida, T.2
Shiohira, S.3
-
17
-
-
0034810211
-
Severely reduced production of klotho in human chronic renal failure kidney
-
Koh N., Fujimori T., Nishiguchi S., et al. Severely reduced production of klotho in human chronic renal failure kidney. Biochem Biophys Res Commun 2001, 280:1015-1020.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 1015-1020
-
-
Koh, N.1
Fujimori, T.2
Nishiguchi, S.3
-
18
-
-
84860778116
-
Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23
-
Lim K., Lu T.S., Molostvov G., et al. Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23. Circulation 2012, 125:2243-2255.
-
(2012)
Circulation
, vol.125
, pp. 2243-2255
-
-
Lim, K.1
Lu, T.S.2
Molostvov, G.3
-
19
-
-
78651408919
-
Klotho deficiency causes vascular calcification in chronic kidney disease
-
Hu M.C., Shi M., Zhang J., et al. Klotho deficiency causes vascular calcification in chronic kidney disease. J Am Soc Nephrol 2011, 22:124-136.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 124-136
-
-
Hu, M.C.1
Shi, M.2
Zhang, J.3
-
20
-
-
34548497123
-
Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study
-
Fliser D., Kollerits B., Neyer U., et al. Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol 2007, 18:2600-2608.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2600-2608
-
-
Fliser, D.1
Kollerits, B.2
Neyer, U.3
-
21
-
-
49249104701
-
Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis
-
Gutierrez O.M., Mannstadt M., Isakova T., et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 2008, 359:584-592.
-
(2008)
N Engl J Med
, vol.359
, pp. 584-592
-
-
Gutierrez, O.M.1
Mannstadt, M.2
Isakova, T.3
-
22
-
-
79958724181
-
Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease
-
Isakova T., Xie H., Yang W., et al. Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA 2011, 305:2432-2439.
-
(2011)
JAMA
, vol.305
, pp. 2432-2439
-
-
Isakova, T.1
Xie, H.2
Yang, W.3
-
23
-
-
77956159370
-
FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment
-
Seiler S., Reichart B., Roth D., Seibert E., Fliser D., Heine G.H. FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment. Nephrol Dial Transpl 2010, 25:3983-3989.
-
(2010)
Nephrol Dial Transpl
, vol.25
, pp. 3983-3989
-
-
Seiler, S.1
Reichart, B.2
Roth, D.3
Seibert, E.4
Fliser, D.5
Heine, G.H.6
-
24
-
-
69249106380
-
High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients
-
Jean G., Terrat J.C., Vanel T., et al. High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients. Nephrol Dial Transpl 2009, 24:2792-2796.
-
(2009)
Nephrol Dial Transpl
, vol.24
, pp. 2792-2796
-
-
Jean, G.1
Terrat, J.C.2
Vanel, T.3
-
25
-
-
80053517709
-
FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis
-
Kendrick J., Cheung A.K., Kaufman J.S., et al. FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis. J Am Soc Nephrol 2011, 22:1913-1922.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1913-1922
-
-
Kendrick, J.1
Cheung, A.K.2
Kaufman, J.S.3
-
26
-
-
80555148939
-
FGF23 induces left ventricular hypertrophy
-
Faul C., Amaral A.P., Oskouei B., et al. FGF23 induces left ventricular hypertrophy. J Clin Invest 2011, 121:4393-4408.
-
(2011)
J Clin Invest
, vol.121
, pp. 4393-4408
-
-
Faul, C.1
Amaral, A.P.2
Oskouei, B.3
-
27
-
-
66349097180
-
Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease
-
Gutierrez O.M., Januzzi J.L., Isakova T., et al. Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. Circulation 2009, 119:2545-2552.
-
(2009)
Circulation
, vol.119
, pp. 2545-2552
-
-
Gutierrez, O.M.1
Januzzi, J.L.2
Isakova, T.3
-
28
-
-
70450230670
-
Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population
-
Mirza M.A., Larsson A., Melhus H., Lind L., Larsson T.E. Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population. Atherosclerosis 2009, 207:546-551.
-
(2009)
Atherosclerosis
, vol.207
, pp. 546-551
-
-
Mirza, M.A.1
Larsson, A.2
Melhus, H.3
Lind, L.4
Larsson, T.E.5
-
29
-
-
77958565641
-
Fibroblast growth factor 23 and fetuin A are independent predictors for the coronary artery disease extent in mild chronic kidney disease
-
Kanbay M., Nicoleta M., Selcoki Y., et al. Fibroblast growth factor 23 and fetuin A are independent predictors for the coronary artery disease extent in mild chronic kidney disease. Clin J Am Soc Nephrol 2010, 5:1780-1786.
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, pp. 1780-1786
-
-
Kanbay, M.1
Nicoleta, M.2
Selcoki, Y.3
-
30
-
-
70349656941
-
Relationship between circulating FGF23 and total body atherosclerosis in the community
-
Mirza M.A., Hansen T., Johansson L., et al. Relationship between circulating FGF23 and total body atherosclerosis in the community. Nephrol Dial Transpl 2009, 24:3125-3131.
-
(2009)
Nephrol Dial Transpl
, vol.24
, pp. 3125-3131
-
-
Mirza, M.A.1
Hansen, T.2
Johansson, L.3
-
31
-
-
67650892239
-
Circulating fibroblast growth factor-23 is associated with vascular dysfunction in the community
-
Mirza M.A., Larsson A., Lind L., Larsson T.E. Circulating fibroblast growth factor-23 is associated with vascular dysfunction in the community. Atherosclerosis 2009, 205:385-390.
-
(2009)
Atherosclerosis
, vol.205
, pp. 385-390
-
-
Mirza, M.A.1
Larsson, A.2
Lind, L.3
Larsson, T.E.4
-
33
-
-
0034130405
-
Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases
-
Nagai R., Saito Y., Ohyama Y., et al. Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases. Cell Mol Life Sci 2000, 57:738-746.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 738-746
-
-
Nagai, R.1
Saito, Y.2
Ohyama, Y.3
-
34
-
-
0034710838
-
In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome
-
Saito Y., Nakamura T., Ohyama Y., et al. In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome. Biochem Biophys Res Commun 2000, 276:767-772.
-
(2000)
Biochem Biophys Res Commun
, vol.276
, pp. 767-772
-
-
Saito, Y.1
Nakamura, T.2
Ohyama, Y.3
-
35
-
-
84870488179
-
Circulating αKlotho influences phosphate handling by controlling FGF23 production
-
Smith R.C., O'Bryan L.M., Farrow E.G., et al. Circulating αKlotho influences phosphate handling by controlling FGF23 production. J Clin Invest 2012, 122:4710-4715.
-
(2012)
J Clin Invest
, vol.122
, pp. 4710-4715
-
-
Smith, R.C.1
O'Bryan, L.M.2
Farrow, E.G.3
-
36
-
-
42449126730
-
Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23
-
Marsell R., Krajisnik T., Goransson H., et al. Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23. Nephrol Dial Transpl 2008, 23:827-833.
-
(2008)
Nephrol Dial Transpl
, vol.23
, pp. 827-833
-
-
Marsell, R.1
Krajisnik, T.2
Goransson, H.3
|