Circulating fibroblast growth factor-23 is associated with vascular dysfunction in the community

Atherosclerosis

Volumn 205, Issue 2, 2009, Pages 385-390

  Mirza, Majd A I ^a   Larsson, Anders ^a   Lind, Lars ^a   Larsson, Tobias E ^a,b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Atherosclerosis; FGF23; Fibroblast growth factor 23; Klotho; Vascular function

Indexed keywords

CALCIUM; CHOLESTEROL; FIBROBLAST GROWTH FACTOR 23; GLUCOSE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PARATHYROID HORMONE; PHOSPHATE; TRIACYLGLYCEROL; VITAMIN D;

AGED; ARTERIAL STIFFNESS; ARTICLE; BIOCHEMISTRY; BLOOD VESSEL FUNCTION; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAUSE OF DEATH; CHRONIC KIDNEY DISEASE; CIGARETTE SMOKING; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; ENDOTHELIAL DYSFUNCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOREARM BLOOD FLOW; GLOMERULUS FILTRATION RATE; HEMODIALYSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTION; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; VASCULAR ENDOTHELIUM; VASODILATATION; VEIN OCCLUSION PLETHYSMOGRAPHY; WAIST CIRCUMFERENCE;

AGED; COHORT STUDIES; ENDOTHELIUM, VASCULAR; FEMALE; FIBROBLAST GROWTH FACTORS; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MODELS, STATISTICAL; QUESTIONNAIRES; RANDOM ALLOCATION; REFERENCE VALUES; RISK FACTORS; SEX FACTORS; VASODILATION;

EID: 67650892239     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.01.001     Document Type: Article

References (23)

1. Goodman W.G., London G., Amann K., et al. Vascular calcification in chronic kidney disease. Am J Kidney Dis 43 (2004) 572-579
2. Blacher J., Guerin A.P., Pannier B., Marchais S.J., and London G.M. Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease. Hypertension 38 (2001) 938-942
3. London G.M. Cardiovascular calcifications in uremic patients: clinical impact on cardiovascular function. J Am Soc Nephrol 14 (2003) S305-309
4. Slinin Y., Foley R.N., and Collins A.J. Calcium, phosphorus, parathyroid hormone and cardiovascular disease in hemodialysis patients: the USRDS waves 1, 3, and 4 study. J Am Soc Nephrol 16 (2005) 1788-1793
5. Moe S.M., and Drueke T.B. Management of secondary hyperparathyroidism: the importance and the challenge of controlling parathyroid hormone levels without elevating calcium, phosphorus, and calcium-phosphorus product. Am J Nephrol 23 (2003) 369-379
6. Block G.A., Klassen P.S., Lazarus J.M., et al. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol 15 (2004) 2208-2218
7. Shimada T., Hasegawa H., Yamazaki Y., et al. FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 19 (2004) 429-435
8. Shimada T., Mizutani S., Muto T., et al. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad Sci USA 98 (2001) 6500-6505
9. Larsson T., Nisbeth U., Ljunggren O., Juppner H., and Jonsson K.B. Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int 64 (2003) 2272-2279
10. Fukagawa M., Nii-Kono T., and Kazama J.J. Role of fibroblast growth factor 23 in health and in chronic kidney disease. Curr Opin Nephrol Hypertens 14 (2005) 325-329
11. Gutierrez O.M., Mannstadt M., Isakova T., et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 359 (2008) 584-592
12. Lind L., Fors N., Hall J., Marttala K., and Stenborg A. A comparison of three different methods to evaluate endothelium-dependent vasodilation in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Arterioscler Thromb Vasc Biol 25 (2005) 2368-2375
13. Flodin M., Jonsson A.S., Hansson L.O., Danielsson L.A., and Larsson A. Evaluation of Gentian cystatin C reagent on Abbott Ci8200 and calculation of glomerular filtration rate expressed in mL/min/1.73 m(2) from the cystatin C values in mg/L. Scand J Clin Lab Invest 67 (2007) 560-567
14. Yamazaki Y., Okazaki R., Shibata M., et al. Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia. J Clin Endocrinol Metab 87 (2002) 4957-4960
15. Imel E.A., Peacock M., Pitukcheewanont P., et al. Sensitivity of fibroblast growth factor 23 measurements in tumor-induced osteomalacia. J Clin Endocrinol Metab 91 (2006) 2055-2061
16. Lind L., Sarabi M., Millgard J., et al. Methodological aspects of the evaluation of endothelium-dependent vasodilatation in the human forearm. Clin Physiol (Oxf, Engl) 18 (1998) 81-87
17. Lind L., Pettersson K., Johansson K., et al. Analysis of endothelium-dependent vasodilation by use of the radial artery pulse wave obtained by applanation tonometry. Clin Physiol Funct Imaging 23 (2003) 50-57
18. Wilson P.W., D'Agostino R.B., Levy D., et al. Prediction of coronary heart disease using risk factor categories. Circulation 97 (1998) 1837-1847
19. Vita J.A., Treasure C.B., Nabel E.G., et al. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation 81 (1990) 491-497
20. London G.M., Guerin A.P., Marchais S.J., et al. Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant 18 (2003) 1731-1740
21. Kuro-o M., Matsumura Y., Aizawa H., et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390 (1997) 45-51
22. Nagai R., Saito Y., Ohyama Y., et al. Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases. Cell Mol Life Sci 57 (2000) 738-746
23. Saito Y., Yamagishi T., Nakamura T., et al. Klotho protein protects against endothelial dysfunction. Biochem Biophys Res Commun 248 (1998) 324-329