Comparison of 5% versus 15% sucrose intakes as part of a eucaloric diet in overweight and obese subjects: Effects on insulin sensitivity, glucose metabolism, vascular compliance, body composition and lipid profile. A Randomised Controlled Trial

Metabolism: Clinical and Experimental

Volumn 62, Issue 5, 2013, Pages 694-702

  Lewis, Anthony S ^a   Mccourt, Hannah J ^b   Ennis, Cieran N ^a   Bell, Patrick M ^a   Courtney, C Hamish ^a   Mckinley, Michelle C ^b   Young, Ian S ^b   Hunter, Steven J ^a  

^a ROYAL VICTORIA HOSPITAL   (United Kingdom)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Diet; Insulin resistance; Sucrose

Indexed keywords

GLUCOSE; INSULIN; LIPID;

ADULT; ARTICLE; BLOOD VESSEL COMPLIANCE; BODY COMPOSITION; BODY MASS; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CROSSOVER PROCEDURE; FEMALE; GLUCONEOGENESIS; GLUCOSE TOLERANCE; GLUCOSE UTILIZATION; HUMAN; HYPERINSULINEMIA; INSULIN SENSITIVITY; LOW CALORY DIET; MACRONUTRIENT; MALE; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUGAR INTAKE;

ADULT; BODY COMPOSITION; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FEMALE; GLUCOSE; HUMANS; INSULIN RESISTANCE; LIPID METABOLISM; MALE; METABOLOME; MIDDLE AGED; OBESITY; OSMOLAR CONCENTRATION; OVERWEIGHT; SUCROSE; VASCULAR RESISTANCE;

EID: 84876694657     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2012.11.008     Document Type: Article

References (38)

1. S.M. Hofmann, and M.H. Tschöp Dietary sugars: A fat difference J Clin Invest 119 2009 1089 1092
2. L. Arola, M.L. Bonet, and N. Delzenne Summary and general conclusions/outcomes on the role and fate of sugars in human nutrition and health Obes Rev 10 Suppl 1 2009 55 58
3. World Health Organisation Diet, nutrition and the prevention of chronic diseases: report of a joint WHO/FAO expert consultation 2002 World Health Org Geneva (Tech. Rep. Ser., no. 916)
4. M. Spence, M. McKinley, and S.J. Hunter Session 4: CVD, diabetes and cancer: diet, insulin resistance and diabetes: The right (pro)portions Pro Nutr Soc 69 2010 61 69
5. T.A. O'Sullivan, A.P. Bremner, S. O'Neill, and P. Lyons-Wall Glycaemic load is associated with insulin resistance in older Australian women Eur J Clinl Nutr 64 2010 80 87
6. R.N.A. Black, M. Spence, and R. McMahon Effect of eucaloric high- and low-sucrose diets with identical macronutrient profile on insulin resistance and vascular risk Diabetes 55 2006 3566 3572 (Pubitemid 44923618)
7. F.N. Frayn, and S.N. Kingman Dietary sugar and lipid metabolism in humans Am J Clin Nutr 62 1995 250s 263s
8. B.P. Marriott, L. Olsho, L. Haddem, and P. Connor Intake of added sugars and selected nutrients in the United States, National Health and Nutrition Examination Survey (NHANES) 2003-2006 Crit Rev Food Sci Nutr 50 3 2006 228 258
9. W.N. Schofield Predicting basal metabolic rate, new standards and review of previous work Hum Nutr Clin Nutr 39 Suppl 1985 1 96
10. S.J. Hunter, A.C. Boyd, and F.P. O'Harte Demonstration of glycated insulin in human diabetic plasma and decreased biological activity assessed by euglycemic-hyperinsulinemic clamp technique in humans Diabetes 52 2003 492 498 (Pubitemid 36173208)
11. M. Somogyi Determination of blood sugar J Biol Chem 160 1945 69 73
12. R. Steele, J.S. Bishop, A. Dunn, N. Atszuler, I. Rathegeb, and R.C. DeBodo Inhibition by insulin of hepatic glucose production in normal dog Am J Physiol 208 1965 301 306
13. R.C. De Bodo, R. Steele, N. Altszuler, A. Dunn, and J.S. Bishop On the hormonal regulation of carbohydrate metabolism; studies with C14 glucose Rec Prog Horm Res 19 1963 445 488
14. I.B. Wilkinson, S.A. Fuchs, and I.M. Jansen Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis J Hypertens 16 1998 2079 2084 (Pubitemid 29002391)
15. J. Filipovsky, V. Svobodova, and L. Pecen Reproducibility of radial pulse wave analysis in healthy subjects J Hypertens 18 2000 1033 1040
16. I.B. Wilkinson, J.R. Cockcroft, and D.J. Webb Pulse wave analysis and arterial stiffness J Cardiovasc Pharmacol 32 Suppl. 3 1998 S33 S37
17. S.J. Marchais, A.P. Guerin, B.M. Pannier, B.I. Levy, M.E. Safar, and G.M. London Wave reflections and cardiac hypertrophy in chronic uremia: Influence of body size Hypertension 22 1993 876 883 (Pubitemid 23358096)
18. B.A. Mullan, C.N. Ennis, H.J. Fee, I.S. Young, and D.R. McCance Protective effects of ascorbic acid on arterial hemodynamics during acute hyperglycemia Am J Physiol Heart Circ Physiol 287 2004 H1262 H1268
19. M. Hills, and P. Armitage The two-period cross-over clinical trial Br J Clin Pharmacol 8 1979 7 20 (Pubitemid 9234327)
20. L.H. Storlien, N.D. Oakes, D.A. Pan, M. Kusunoki, and A.B. Junkins Syndromes of insulin resistance in the rat. Inducement by diet and amelioration with benfluorex Diabetes 42 1993 457 462 (Pubitemid 23066523)
21. A.W. Thorburn, L.H. Storlien, A.B. Jenkins, S. Khouri, and E.W. Kraegen Fructose-induced in vivo insulin resistance and elevated plasma triglyceride levels in rats Am J Clin Nutr 49 1989 1155 1163 (Pubitemid 19169675)
22. I. Zavaroni, S. Sander, S. Scott, and G.M. Reaven Effect of fructose feeding on insulin secretion and insulin action in the rat Metabolism 29 1980 970 973 (Pubitemid 10014402)
23. E. Pamies-Andreu, M. Fiksen-Olsen, R.A. Rizza, and J.C. Romero High-fructose feeding elicits insulin resistance without hypertension in normal mongrel dogs Am J Hypertens 8 1995 732 738
24. M.J. Pagliassotti, K.A. Shahrokhi, and M. Moscarello Involvement of liver and skeletal muscle in sucrose-induced insulin resistance: dose-response studies Am J Physiol 266 1994 R1637 R1644
25. F. Martinez, R.A. Rizza, and R.C. Romero High-fructose feeding elicits insulin resistance, hyperinsulinism and hypertension in normal dogs Hypertension 23 1994 456 463 (Pubitemid 24102041)
26. B. Kiens, and E.A. Richter Types of carbohydrate in an ordinary diet affect insulin action and muscle substrates in humans Am J Clin Nutr 63 1996 47 53 (Pubitemid 26005726)
27. K.A. Lê, M. Ith, and R. Kreis Fructose overconsumption in healthy subjects with and without a family history of type 2 diabetes Am J Clin Nutr 89 2009 1760 1765
28. V. Koivisto, and H. Yki-Jarvinen Fructose and insulin sensitivity in patients with type 2 diabetes J Intern Med 233 1993 145 153 (Pubitemid 23068317)
29. A.W. Thorburn, P.A. Crapo, K. Griver, P. Wallace, and R.R. Henry Long-term effects of dietary fructose on carbohydrate metabolism in non-insulin dependent diabetes mellitus Metabolism 39 1990 58 63 (Pubitemid 20027708)
30. A.E. Byrnes, and G.S. Frost Increased sucrose intake is not associated with a change in glucose or insulin sensitivity in people with type 2 diabetes Int J Food Sci Nutr 58 8 2007 644 651 (Pubitemid 350148711)
31. M.E. Daly, M. Townsley, and C.P. Vale Dietary carbohydrate source and insulin sensitivity Diabet Med 14 Suppl. 1997 S25 (abstr)
32. R.A. DeFronzo, E. Ferrannini, and D.C. Simonson Fasting hyperglycaemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake Metabolism 34 1989 387 395 (Pubitemid 19105727)
33. M. Albareda, J. Rodríguez-Espinosa, M. Murugo, A. de Leiva, and R. Corcoy Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test Diabetologia 43 2000 1507 1511 (Pubitemid 32734856)
34. M. Horowitz, M.A. Edelbroek, J.M. Wishart, and J.W. Straathof Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects Diabetologia 36 1993 857 862 (Pubitemid 23248159)
35. G.T. Ko, J.C. Chan, and J. Woo The reproducibility and usefulness of the oral glucose tolerance test in screening for diabetes and other cardiovascular risk factors Ann Clin Biochem 35 pt1 1998 62 67 (Pubitemid 28043626)
36. R.N. Bergman, K. Hückling, and M. Watanabe Chapter 16 measuring insulin action in vivo R.A. DeFronzo, E. Ferrannini, H. Keen, P. Zimmet, International textbook of diabetes mellitus 3rd ed 2004 Wiley
37. A. Tirosh, I. Shai, and D. Tekes-Manova Normal fasting plasma glucose levels and type 2 diabetes in young men N Engl J Med 353 2005 1454 1462 (Pubitemid 41400919)
38. M.R. Graham, P. Evans, B. Davies, and J.S. Baker Arterial pulse wave velocity, inflammatory markers, pathological GH and IGF states, cardiovascular and cerebrovascular disease Vasc Health Risk Manag 4 2008 1361 1371