Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development

Neural Development

Volumn 8, Issue 1, 2013, Pages

  Tang, Mianzhi ^a   Luo, Sarah X ^a,b   Tang, Vivian ^a   Huang, Eric J ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3BETA; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR NKX6.1; G PROTEIN COUPLED RECEPTOR; SHH PROTEIN, MOUSE; SMO PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIMB MALFORMATION; MESENCEPHALON; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OCULOMOTOR NUCLEUS; PROTEIN EXPRESSION; RAPHE NUCLEUS; RED NUCLEUS; SEROTONINERGIC NERVE CELL; SHH SIGNALING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WNT SIGNALING PATHWAY; ANIMAL; CELL DIFFERENTIATION; CELL LINEAGE; CYTOLOGY; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE; PRENATAL DEVELOPMENT;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; DOPAMINERGIC NEURONS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; MESENCEPHALON; MICE; MICE, TRANSGENIC; NEUROGENESIS; RECEPTORS, G-PROTEIN-COUPLED; WNT SIGNALING PATHWAY;

EID: 84876691602     PISSN: None     EISSN: 17498104     Source Type: Journal    
DOI: 10.1186/1749-8104-8-8     Document Type: Article

References (43)

1. Jessell TM. Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nat Rev Genet 2000, 1:20-29. 10.1038/35049541, 11262869.
2. Fuccillo M, Joyner AL, Fishell G. Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development. Nat Rev Neurosci 2006, 7:772-783. 10.1038/nrn1990, 16988653.
3. Chamberlain CE, Jeong J, Guo C, Allen BL, McMahon AP. Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development 2008, 135:1097-1106. 10.1242/dev.013086, 18272593.
4. Dessaud E, Ribes V, Balaskas N, Yang LL, Pierani A, Kicheva A, Novitch BG, Briscoe J, Sasai N. Dynamic assignment and maintenance of positional identity in the ventral neural tube by the morphogen sonic hedgehog. PLoS Biol 2010, 8:e1000382. 10.1371/journal.pbio.1000382, 2879390, 20532235.
5. Dessaud E, Yang LL, Hill K, Cox B, Ulloa F, Ribeiro A, Mynett A, Novitch BG, Briscoe J. Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism. Nature 2007, 450:717-720. 10.1038/nature06347, 18046410.
6. Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, Page KM, Briscoe J, Ribes V. Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell 2012, 148:273-284. 10.1016/j.cell.2011.10.047, 3267043, 22265416.
7. Balordi F, Fishell G. Hedgehog signaling in the subventricular zone is required for both the maintenance of stem cells and the migration of newborn neurons. J Neurosci 2007, 27:5936-5947. 10.1523/JNEUROSCI.1040-07.2007, 17537964.
8. Blaess S, Corrales JD, Joyner AL. Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development 2006, 133:1799-1809. 10.1242/dev.02339, 16571630.
9. Fuccillo M, Rallu M, McMahon AP, Fishell G. Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development 2004, 131:5031-5040. 10.1242/dev.01349, 15371303.
10. Xu Q, Guo L, Moore H, Waclaw RR, Campbell K, Anderson SA. Sonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates. Neuron 2010, 65:328-340. 10.1016/j.neuron.2010.01.004, 2868511, 20159447.
11. Hynes M, Porter JA, Chiang C, Chang D, Tessier-Lavigne M, Beachy PA, Rosenthal A. Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron 1995, 15:35-44. 10.1016/0896-6273(95)90062-4, 7619528.
12. Ye W, Shimamura K, Rubenstein JL, Hynes MA, Rosenthal A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 1998, 93:755-766. 10.1016/S0092-8674(00)81437-3, 9630220.
13. Blaess S, Bodea GO, Kabanova A, Chanet S, Mugniery E, Derouiche A, Stephen D, Joyner AL. Temporal-spatial changes in sonic hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural Dev 2011, 6:29. 10.1186/1749-8104-6-29, 3135491, 21689430.
14. Hayes L, Zhang Z, Albert P, Zervas M, Ahn S. Timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons. J Comp Neurol 2011, 519:3001-3018. 10.1002/cne.22711, 3154975, 21713771.
15. Joksimovic M, Anderegg A, Roy A, Campochiaro L, Yun B, Kittappa R, McKay R, Awatramani R. Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools. Proc Natl Acad Sci U S A 2009, 106:19185-19190. 10.1073/pnas.0904285106, 2776440, 19850875.
16. Zervas M, Millet S, Ahn S, Joyner AL. Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron 2004, 43:345-357. 10.1016/j.neuron.2004.07.010, 15294143.
17. Perez-Balaguer A, Puelles E, Wurst W, Martinez S. Shh dependent and independent maintenance of basal midbrain. Mech Dev 2009, 126:301-313. 10.1016/j.mod.2009.03.001, 19298856.
18. Chi CL, Martinez S, Wurst W, Martin GR. The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development 2003, 130:2633-2644. 10.1242/dev.00487, 12736208.
19. Crossley PH, Martinez S, Martin GR. Midbrain development induced by FGF8 in the chick embryo. Nature 1996, 380:66-68. 10.1038/380066a0, 8598907.
20. Smidt MP, Burbach JP. How to make a mesodiencephalic dopaminergic neuron. Nat Rev Neurosci 2007, 8:21-32. 10.1038/nrn2039, 17180160.
21. Tang M, Miyamoto Y, Huang EJ. Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons. Development 2009, 136:2027-2038. 10.1242/dev.034330, 2685724, 19439492.
22. Zhang J, Pho V, Bonasera SJ, Holzmann J, Tang AT, Hellmuth J, Tang S, Janak PH, Tecott LH, Huang EJ. Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nat Neurosci 2007, 10:77-86. 10.1038/nn1816, 3578579, 17159989.
23. Wiggins AK, Wei G, Doxakis E, Wong C, Tang AA, Zang K, Luo EJ, Neve RL, Reichardt LF, Huang EJ. Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival. J cell Biol 2004, 25:257-267.
24. Briscoe J, Ericson J. The specification of neuronal identity by graded sonic hedgehog signalling. Semin Cell Dev Biol 1999, 10:353-362. 10.1006/scdb.1999.0295, 10441550.
25. Briscoe J, Pierani A, Jessell TM, Ericson J. A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 2000, 101:435-445. 10.1016/S0092-8674(00)80853-3, 10830170.
26. Ahn S, Joyner AL. Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning. Cell 2004, 118:505-516. 10.1016/j.cell.2004.07.023, 15315762.
27. Puelles E, Annino A, Tuorto F, Usiello A, Acampora D, Czerny T, Brodski C, Ang SL, Wurst W, Simeone A. Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain. Development 2004, 131:2037-2048. 10.1242/dev.01107, 15105370.
28. Ribes V, Briscoe J. Establishing and interpreting graded sonic hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback. Cold Spring Harb Perspect Biol 2009, 1:a002014. 10.1101/cshperspect.a002014, 2742090, 20066087.
29. Tang M, Villaescusa JC, Luo SX, Guitarte C, Lei S, Miyamoto Y, Taketo MM, Arenas E, Huang EJ. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. J Neurosci 2010, 30:9280-9291. 3578394, 20610763.
30. Cheng L, Chen CL, Luo P, Tan M, Qiu M, Johnson R, Ma Q. Lmx1b, Pet-1, and Nkx2.2 coordinately specify serotonergic neurotransmitter phenotype. J Neurosci 2003, 23:9961-9967.
31. Prakash N, Puelles E, Freude K, Trumbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, et al. Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. Development 2009, 136:2545-2555. 10.1242/dev.031781, 2729334, 19592574.
32. Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev 2004, 18:937-951. 10.1101/gad.1190304, 395852, 15107405.
33. Lahti L, Peltopuro P, Piepponen TP, Partanen J. Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain. Development 2012, 139:894-905. 10.1242/dev.071936, 22278924.
34. Maretto S, Cordenonsi M, Dupont S, Braghetta P, Broccoli V, Hassan AB, Volpin D, Bressan GM, Piccolo S. Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A 2003, 100:3299-3304. 10.1073/pnas.0434590100, 152286, 12626757.
35. Joksimovic M, Yun BA, Kittappa R, Anderegg AM, Chang WW, Taketo MM, McKay RD, Awatramani RB. Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis. Nat Neurosci 2009, 12:125-131. 10.1038/nn.2243, 19122665.
36. Nakatani T, Minaki Y, Kumai M, Ono Y. Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon. Development 2007, 134:2783-2793. 10.1242/dev.02870, 17611227.
37. Harfe BD, Scherz PJ, Nissim S, Tian H, McMahon AP, Tabin CJ. Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell 2004, 118:517-528. 10.1016/j.cell.2004.07.024, 15315763.
38. Agarwala S, Sanders TA, Ragsdale CW. Sonic hedgehog control of size and shape in midbrain pattern formation. Science 2001, 291:2147-2150. 10.1126/science.1058624, 11251119.
39. Bayly RD, Ngo M, Aglyamova GV, Agarwala S. Regulation of ventral midbrain patterning by Hedgehog signaling. Development 2007, 134:2115-2124. 10.1242/dev.02850, 17507412.
40. Evinger C. Extraocular motor nuclei: location, morphology and afferents. Rev Oculomot Res 1988, 2:81-117.
41. Feldman JL, Mitchell GS, Nattie EE. Breathing: rhythmicity, plasticity, chemosensitivity. Annu Rev Neurosci 2003, 26:239-266. 10.1146/annurev.neuro.26.041002.131103, 2811316, 12598679.
42. Massion J. Red nucleus: past and future. Behav Brain Res 1988, 28:1-8. 10.1016/0166-4328(88)90071-X, 3382508.
43. Chung S, Leung A, Han BS, Chang MY, Moon JI, Kim CH, Hong S, Pruszak J, Isacson O, Kim KS. Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway. Cell Stem Cell 2009, 5:646-658. 10.1016/j.stem.2009.09.015, 2788512, 19951692.