Intracisternal administration of SB203580, a p38 mitogen-activated protein kinase inhibitor, attenuates cerebral vasospasm via inhibition of tumor-necrosis factor-α

Journal of Clinical Neuroscience

Volumn 20, Issue 5, 2013, Pages 726-730

  Pan, Yun Xi ^a   Chen, Ke Fei ^b   Lin, Yi Xing ^a   Wu, Wei ^a   Zhou, Xiao Ming ^a   Zhang, Xiang Sheng ^a   Zhang, Xin ^a   Shi, Ji Xin ^a  

^a NANJING UNIVERSITY   (China)

^b Department of Neurosurgery   (China)

Author keywords

Cerebral vasospasm; p38 Mitogen activated protein kinase; SB203580; Subarachnoid hemorrhage; Tumor necrosis factor

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASILAR ARTERY; BRAIN VASOSPASM; CEREBROSPINAL FLUID; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RABBIT; SUBARACHNOID HEMORRHAGE;

ANIMALS; BASILAR ARTERY; DIMETHYL SULFOXIDE; DISEASE MODELS, ANIMAL; IMIDAZOLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PYRIDINES; RABBITS; SUBARACHNOID HEMORRHAGE; TUMOR NECROSIS FACTOR-ALPHA; VASOSPASM, INTRACRANIAL;

EID: 84876664546     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2012.09.012     Document Type: Article

References (28)

1. V.G. Khurana, and M. Besser Pathophysiological basis of cerebral vasospasm following aneurysmal subarachnoid haemorrhage J Clin Neurosci 4 1997 122 131
2. B.R. Bendok, C.C. Getch, and T.W. Malisch Treatment of aneurysmal subarachnoid hemorrhage Semin Neurol 18 1998 521 531
3. R.H. Wilkins Attempts at treatment of intracranial arterial spasm in animals and human beings Surg Neurol 1 1973 148 159
4. R.H. Wilkins Attempts at prevention or treatment of intracranial arterial spasm: an update Neurosurgery 18 1986 808 825
5. G. Pearson, F. Robinson, and T. Beers Gibson Mitogen-activated protein (map) kinase pathways: regulation and physiological functions Endocr Rev 22 2001 153 183
6. A.M. Epstein, D. Throckmorton, and C.M. Brophy Mitogen-activated protein kinase activation: an alternate signaling pathway for sustained vascular smooth muscle contraction J Vasc Surg 26 1997 327 332
7. K. Aoki, A.Y. Zubkov, and R.E. Tibbs Role of mapk in chronic cerebral vasospasm Life Sci 70 2002 1901 1908
8. M. Satoh, A.D. Parent, and J.H. Zhang Inhibitory effect with antisense mitogen-activated protein kinase oligodeoxynucleotide against cerebral vasospasm in rats Stroke 33 2002 775 781
9. R. Tibbs, A. Zubkov, and K. Aoki Effects of mitogen-activated protein kinase inhibitors on cerebral vasospasm in a double-hemorrhage model in dogs J Neurosurg 93 2000 1041 1047
10. A.Y. Zubkov, K. Ogihara, and P. Tumu Mitogen-activated protein kinase mediation of hemolysate-induced contraction in rabbit basilar artery J Neurosurg 90 1999 1091 1097
11. A.Y. Zubkov, R.E. Tibbs, and K. Aoki Prevention of vasospasm in penetrating arteries with mapk inhibitors in dog double-hemorrhage model Surg Neurol 54 2000 221 227 [discussion 7-8]
12. A.Y. Zubkov, K.S. Rollins, and B. McGehee Relaxant effect of u0126 in hemolysate-, oxyhemoglobin-, and bloody cerebrospinal fluid-induced contraction in rabbit basilar artery Stroke 32 2001 154 161
13. T. Sasaki, H. Kasuya, and H. Onda Role of p38 mitogen-activated protein kinase on cerebral vasospasm after subarachnoid hemorrhage Stroke 35 2004 1466 1470
14. J.C. Lee, S. Kassis, and S. Kumar P38 mitogen-activated protein kinase inhibitors-mechanisms and therapeutic potentials Pharmacol Ther 82 1999 389 397
15. R.J. Gum, M.M. McLaughlin, and S. Kumar Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, sb 203580, by alteration of one or more amino acids within the atp binding pocket J Biol Chem 273 1998 15605 15610
16. P.R. Young, M.M. McLaughlin, and S. Kumar Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the atp site J Biol Chem 272 1997 12116 12121
17. K.A. Hanafy, R.M. Stuart, and A.G. Khandji Relationship between brain interstitial fluid tumor necrosis factor-alpha and cerebral vasospasm after aneurysmal subarachnoid hemorrhage J Clin Neurosci 17 2010 853 856
18. M.L. Zhou, J.X. Shi, and J.Q. Zhu Comparison between one- and two-hemorrhage models of cerebral vasospasm in rabbits J Neurosci Methods 159 2007 318 324
19. M.L. Zhou, J.X. Shi, and C.H. Hang Potential contribution of nuclear factor-kappaB to cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits J Cereb Blood Flow Metab 27 2007 1583 1592
20. M.L. Zhou, W. Wu, and Y.S. Ding Expression of toll-like receptor 4 in the basilar artery after experimental subarachnoid hemorrhage in rabbits: a preliminary study Brain Res 1173 2007 110 116
21. Y. Wu, X.D. Zhao, and Z. Zhuang Peroxisome proliferator-activated receptor gamma agonist rosiglitazone attenuates oxyhemoglobin-induced toll-like receptor 4 expression in vascular smooth muscle cells Brain Res 1322 2010 102 108
22. C.L. Lin, A.L. Kwan, and A.S. Dumont Attenuation of experimental subarachnoid hemorrhage-induced increases in circulating intercellular adhesion molecule-1 and cerebral vasospasm by the endothelin-converting enzyme inhibitor cgs 26303 J Neurosurg 106 2007 442 448
23. L.F. Lopez-Cortes, R. Marquez-Arbizu, and L.M. Jimenez-Jimenez Cerebrospinal fluid tumor necrosis factor-alpha, interleukin-1beta, interleukin-6, and interleukin-8 as diagnostic markers of cerebrospinal fluid infection in neurosurgical patients Crit Care Med 28 2000 215 219
24. K.A. Hanafy, B. Grobelny, and L. Fernandez Brain interstitial fluid TNF-alpha after subarachnoid hemorrhage J Neurol Sci 291 2010 69 73
25. C. Vecchione, A. Frati, and A. Di Pardo Tumor necrosis factor-alpha mediates hemolysis-induced vasoconstriction and the cerebral vasospasm evoked by subarachnoid hemorrhage Hypertension 54 2009 150 156
26. S. Basuroy, D. Tcheranova, and S. Bhattacharya Nox4 nadph oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during tnf-alpha-induced apoptosis Am J Physiol Cell Physiol 300 2011 C256 C265
27. S. Grethe, M.P. Ares, and T. Andersson P38 mapk mediates tnf-induced apoptosis in endothelial cells via phosphorylation and downregulation of bcl-x(l) Exp Cell Res 298 2004 632 642
28. X. Zhang, X.D. Zhao, and J.X. Shi Inhibition of the p38 mitogen-activated protein kinase (mapk) pathway attenuates cerebral vasospasm following experimental subarachnoid hemorrhage in rabbits Ann Clin Lab Sci 41 2011 244 250