메뉴 건너뛰기




Volumn 31, Issue 5, 2013, Pages 1010-1021

Elevated Id2 expression results in precocious neural stem cell depletion and abnormal brain development

Author keywords

Apoptosis; Brain tumor; CyclinG1; Glioma; Id2; Medulloblastoma; Neural stem cells; Rett syndrome; Seizure; Self renewal

Indexed keywords

CYCLIN G1; INHIBITOR OF DIFFERENTIATION 2; PROTEIN P53;

EID: 84876554264     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1351     Document Type: Article
Times cited : (18)

References (52)
  • 1
    • 0035499887 scopus 로고    scopus 로고
    • The development of neural stem cells
    • DOI 10.1038/35102174
    • Temple S. The development of neural stem cells. Nature 2001;414:112-117. (Pubitemid 33041635)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 112-117
    • Temple, S.1
  • 3
    • 19544386970 scopus 로고    scopus 로고
    • Roles of bHLH genes in neural stem cell differentiation
    • DOI 10.1016/j.yexcr.2005.03.015, PII S0014482705001266, Molecular Control of Stem Cell Differentiation
    • Kageyama R, Ohtsuka T, Hatakeyama J et al. Roles of bHLH genes in neural stem cell differentiation. Exp Cell Res 2005;306:343-348. (Pubitemid 40732759)
    • (2005) Experimental Cell Research , vol.306 , Issue.2 , pp. 343-348
    • Kageyama, R.1    Ohtsuka, T.2    Hatakeyama, J.3    Ohsawa, R.4
  • 4
    • 0036471609 scopus 로고    scopus 로고
    • Molecular mechanisms underlying cell fate specification in the developing telencephalon
    • DOI 10.1016/S0959-4388(02)00286-6
    • Schuurmans C, Guillemot F. Molecular mechanisms underlying cell fate specification in the developing telencephalon. Curr Opin Neurobiol 2002;12:26-34. (Pubitemid 34175271)
    • (2002) Current Opinion in Neurobiology , vol.12 , Issue.1 , pp. 26-34
    • Schuurmans, C.1    Guillemot, F.2
  • 5
    • 9444261000 scopus 로고    scopus 로고
    • Id4 regulates neural progenitor proliferation and differentiation in vivo
    • DOI 10.1242/dev.01430
    • Yun K, Mantani A, Garel S et al. Id4 regulates neural progenitor proliferation and differentiation in vivo. Development 2004;131:5441-5448. (Pubitemid 39562186)
    • (2004) Development , vol.131 , Issue.21 , pp. 5441-5448
    • Yun, K.1    Mantani, A.2    Garel, S.3    Rubenstein, J.4    Israel, M.A.5
  • 6
    • 0033554723 scopus 로고    scopus 로고
    • Id1 and Id3 are required for neurogenesis, angiogenesis, and vascularization of tumor xenografts
    • Lyden D, Young AZ, Zagzag D et al. Id1 and Id3 are required for neurogenesis, angiogenesis, and vascularization of tumor xenografts. Nature 1999;401:670-677.
    • (1999) Nature , vol.401 , pp. 670-677
    • Lyden, D.1    Young, A.Z.2    Zagzag, D.3
  • 7
    • 33745609276 scopus 로고    scopus 로고
    • Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome
    • DOI 10.1093/hmg/ddl124
    • Peddada S, Yasui DH, Lasalle JM. Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome. Hum Mol Genet 2006;15:2003-2014. (Pubitemid 43983274)
    • (2006) Human Molecular Genetics , vol.15 , Issue.12 , pp. 2003-2014
    • Peddada, S.1    Yasui, D.H.2    LaSalle, J.M.3
  • 8
    • 23144464750 scopus 로고    scopus 로고
    • Id family of helix-loop-helix proteins in cancer
    • DOI 10.1038/nrc1673
    • Perk J, Iavarone A, Benezra R. Id family of helix-loop-helix proteins in cancer. Nat Rev Cancer 2005;5:603-614. (Pubitemid 41081386)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.8 , pp. 603-614
    • Perk, J.1    Iavarone, A.2    Benezra, R.3
  • 9
    • 0025238437 scopus 로고
    • The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
    • Benezra R, Davis RL, Lockshon D et al. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins. Cell 1990;61:49-59.
    • (1990) Cell , vol.61 , pp. 49-59
    • Benezra, R.1    Davis, R.L.2    Lockshon, D.3
  • 10
    • 0042347689 scopus 로고    scopus 로고
    • Id proteins in development, cell cycle and cancer
    • DOI 10.1016/S0962-8924(03)00147-8
    • Ruzinova MB, Benezra R. Id proteins in development, cell cycle and cancer. Trends Cell Biol 2003;13:410-418. (Pubitemid 36897645)
    • (2003) Trends in Cell Biology , vol.13 , Issue.8 , pp. 410-418
    • Ruzinova, M.B.1    Benezra, R.2
  • 11
    • 0034609818 scopus 로고    scopus 로고
    • Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
    • Lasorella A, Noseda M, Beyna M et al. Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature 2000;407:592-598.
    • (2000) Nature , vol.407 , pp. 592-598
    • Lasorella, A.1    Noseda, M.2    Beyna, M.3
  • 13
    • 0031015297 scopus 로고    scopus 로고
    • Each member of the Id gene family exhibits a unique expression pattern in mouse gastrulation and neurogenesis
    • DOI 10.1002/(SICI)1097-0177(199701)208:1<92::AID
    • Jen Y, Manova K, Benezra R. Each member of the Id gene family exhibits a unique expression pattern in mouse gastrulation and neurogenesis. Dev Dyn 1997;208:92-106. (Pubitemid 27030487)
    • (1997) Developmental Dynamics , vol.208 , Issue.1 , pp. 92-106
    • Jen, Y.1    Manova, K.2    Benezra, R.3
  • 16
    • 79961027714 scopus 로고    scopus 로고
    • Inhibitor of DNA binding 2 promotes sensory axonal growth after SCI
    • Yu P, Zhang YP, Shields LB et al. Inhibitor of DNA binding 2 promotes sensory axonal growth after SCI. Exp Neurol 2011;231:38-44.
    • (2011) Exp Neurol , vol.231 , pp. 38-44
    • Yu, P.1    Zhang, Y.P.2    Shields, L.B.3
  • 18
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • DOI 10.1016/S0092-8674(03)00847-X
    • Ying QL, Nichols J, Chambers I et al. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003;115:281-292. (Pubitemid 37487702)
    • (2003) Cell , vol.115 , Issue.3 , pp. 281-292
    • Ying, Q.-L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 19
    • 70350494493 scopus 로고    scopus 로고
    • High levels of Id1 expression define B1 type adult neural stem cells
    • Nam HS, Benezra R. High levels of Id1 expression define B1 type adult neural stem cells. Cell Stem Cell 2009;5:515-526.
    • (2009) Cell Stem Cell , vol.5 , pp. 515-526
    • Nam, H.S.1    Benezra, R.2
  • 20
    • 78649986150 scopus 로고    scopus 로고
    • TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma
    • Anido J, Saez-Borderias A, Gonzalez-Junca A et al. TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma. Cancer Cell 2010;18:655-668.
    • (2010) Cancer Cell , vol.18 , pp. 655-668
    • Anido, J.1    Saez-Borderias, A.2    Gonzalez-Junca, A.3
  • 21
    • 48749083583 scopus 로고    scopus 로고
    • Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling
    • Jeon HM, Jin X, Lee JS et al. Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling. Genes Dev 2008;22:2028-2033.
    • (2008) Genes Dev , vol.22 , pp. 2028-2033
    • Jeon, H.M.1    Jin, X.2    Lee, J.S.3
  • 22
    • 5644275143 scopus 로고    scopus 로고
    • Id2 drives differentiation and suppresses tumor formation in the intestinal epithelium
    • DOI 10.1158/0008-5472.CAN-04-2095
    • Russell RG, Lasorella A, Dettin LE et al. Id2 drives differentiation and suppresses tumor formation in the intestinal epithelium. Cancer Res 2004;64:7220-7225. (Pubitemid 39372055)
    • (2004) Cancer Research , vol.64 , Issue.20 , pp. 7220-7225
    • Russell, R.G.1    Lasorella, A.2    Dettin, L.E.3    Iavarone, A.4
  • 23
    • 53049095294 scopus 로고    scopus 로고
    • Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations
    • Yan W, Liu G, Scoumanne A et al. Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations. Cancer Res 2008;68:6789-6796.
    • (2008) Cancer Res , vol.68 , pp. 6789-6796
    • Yan, W.1    Liu, G.2    Scoumanne, A.3
  • 24
    • 0035914345 scopus 로고    scopus 로고
    • Id-1, ITF-2, and Id-2 comprise a network of helix-loop-helix proteins that regulate mammary epithelial cell proliferation, differentiation, and apoptosis
    • Parrinello S, Lin CQ, Murata K et al. Id-1, ITF-2, and Id-2 comprise a network of helix-loop-helix proteins that regulate mammary epithelial cell proliferation, differentiation, and apoptosis. J Biol Chem 2001;276:39213-39219.
    • (2001) J Biol Chem , vol.276 , pp. 39213-39219
    • Parrinello, S.1    Lin, C.Q.2    Murata, K.3
  • 26
    • 79960102625 scopus 로고    scopus 로고
    • p53 directly represses Id2 to inhibit the proliferation of neural progenitor cells
    • Paolella BR, Havrda MC, Mantani A et al. p53 directly represses Id2 to inhibit the proliferation of neural progenitor cells. Stem Cells 2011;29:1090-1101.
    • (2011) Stem Cells , vol.29 , pp. 1090-1101
    • Paolella, B.R.1    Havrda, M.C.2    Mantani, A.3
  • 27
    • 0035874914 scopus 로고    scopus 로고
    • Electroconvulsive thresholds of inbred mouse strains
    • DOI 10.1006/geno.2001.6564
    • Frankel WN, Taylor L, Beyer B et al. Electroconvulsive thresholds of inbred mouse strains. Genomics 2001;74:306-312. (Pubitemid 32675354)
    • (2001) Genomics , vol.74 , Issue.3 , pp. 306-312
    • Frankel, W.N.1    Taylor, L.2    Beyer, B.3    Tempel, B.L.4    White H.Steve5
  • 28
    • 34547629265 scopus 로고    scopus 로고
    • Complex seizure disorder caused by Brunol4 deficiency in mice
    • Yang Y, Mahaffey CL, Berube N et al. Complex seizure disorder caused by Brunol4 deficiency in mice. Plos Genetics 2007;3:e124.
    • (2007) Plos Genetics , vol.3
    • Yang, Y.1    Mahaffey, C.L.2    Berube, N.3
  • 29
    • 0342732880 scopus 로고    scopus 로고
    • Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures
    • DOI 10.1006/dbio.2000.9732
    • Hébert JM, McConnell SK. Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol 2000;222:296-306. (Pubitemid 30416368)
    • (2000) Developmental Biology , vol.222 , Issue.2 , pp. 296-306
    • Hebert, J.M.1    McConnell, S.K.2
  • 30
    • 0035146487 scopus 로고    scopus 로고
    • Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon
    • Yun K, Potter S, Rubenstein JL. Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon. Development 2001;128:193-205. (Pubitemid 32124145)
    • (2001) Development , vol.128 , Issue.2 , pp. 193-205
    • Yun, K.1    Potter, S.2    Rubenstein, J.L.R.3
  • 31
    • 12144266963 scopus 로고    scopus 로고
    • Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex
    • DOI 10.1523/JNEUROSCI.2899-04.2005
    • Englund C, Fink A, Lau C et al. Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci 2005;25:247-251. (Pubitemid 40110787)
    • (2005) Journal of Neuroscience , vol.25 , Issue.1 , pp. 247-251
    • Englund, C.1    Fink, A.2    Lau, C.3    Pham, D.4    Daza, R.A.M.5    Bulfone, A.6    Kowalczyk, T.7    Hevner, R.F.8
  • 32
    • 58149381987 scopus 로고    scopus 로고
    • Id2 is required for specification of dopaminergic neurons during adult olfactory neurogenesis
    • Havrda MC, Harris BT, Mantani A et al. Id2 is required for specification of dopaminergic neurons during adult olfactory neurogenesis. J Neurosci 2008;28:14074-14086.
    • (2008) J Neurosci , vol.28 , pp. 14074-14086
    • Havrda, M.C.1    Harris, B.T.2    Mantani, A.3
  • 33
    • 77951209155 scopus 로고    scopus 로고
    • Neurogenin 1 (Neurog1) expression in the ventral neural tube is mediated by a distinct enhancer and preferentially marks ventral interneuron lineages
    • Quinones HI, Savage TK, Battiste J et al. Neurogenin 1 (Neurog1) expression in the ventral neural tube is mediated by a distinct enhancer and preferentially marks ventral interneuron lineages. Dev Biol 2010;340:283-292.
    • (2010) Dev Biol , vol.340 , pp. 283-292
    • Quinones, H.I.1    Savage, T.K.2    Battiste, J.3
  • 34
    • 79953133669 scopus 로고    scopus 로고
    • Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system
    • Kim EJ, Hori K, Wyckoff A et al. Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system. J Comp Neurol 2011;519:1355-1370.
    • (2011) J Comp Neurol , vol.519 , pp. 1355-1370
    • Kim, E.J.1    Hori, K.2    Wyckoff, A.3
  • 35
    • 84976338075 scopus 로고
    • Mitosis in the neural tube
    • Sauer FC. Mitosis in the neural tube. J Comp Neurol 1935;62:377-405.
    • (1935) J Comp Neurol , vol.62 , pp. 377-405
    • Sauer, F.C.1
  • 37
    • 60149090604 scopus 로고    scopus 로고
    • p53 regulates the self-renewal and differentiation of neural precursors
    • Armesilla-Diaz A, Bragado P, Del Valle I et al. p53 regulates the self-renewal and differentiation of neural precursors. Neuroscience 2009;158:1378-1389.
    • (2009) Neuroscience , vol.158 , pp. 1378-1389
    • Armesilla-Diaz, A.1    Bragado, P.2    Del Valle, I.3
  • 38
    • 62649094925 scopus 로고    scopus 로고
    • GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
    • Stecca B, Ruiz i Altaba A. A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers. EMBO J 2009;28:663-676.
    • (2009) EMBO J , vol.28 , pp. 663-676
    • Stecca, B.1    Ruiz I Altaba, A.A.2
  • 39
    • 0031035550 scopus 로고    scopus 로고
    • Id genes encoding inhibitors of transcription are expressed during in Vitro astrocyte differentiation and in cell lines derived from astrocytic tumors
    • Andres-Barquin PJ, Hernandez MC, Hayes TE et al. Id genes encoding inhibitors of transcription are expressed during in vitro astrocyte differentiation and in cell lines derived from astrocytic tumors. Cancer Res 1997;57:215-220. (Pubitemid 27036596)
    • (1997) Cancer Research , vol.57 , Issue.2 , pp. 215-220
    • Andres-Barquin, P.J.1    Hernandez, M.-C.2    Hayes, T.E.3    McKay, R.D.G.4    Israel, M.A.5
  • 40
    • 0842287501 scopus 로고    scopus 로고
    • Id proteins in neural cancer
    • DOI 10.1016/S0304-3835(03)00455-5
    • Iavarone A, Lasorella A. Id proteins in neural cancer. Cancer Lett 2004;204:189-196. (Pubitemid 38167722)
    • (2004) Cancer Letters , vol.204 , Issue.2 , pp. 189-196
    • Iavarone, A.1    Lasorella, A.2
  • 42
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008;455:1061-1068.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 44
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene-induced DNA damage model for cancer development
    • DOI 10.1126/science.1140735
    • Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008;319:1352-1355. (Pubitemid 351354863)
    • (2008) Science , vol.319 , Issue.5868 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 47
    • 79960977943 scopus 로고    scopus 로고
    • Cyclin D1 promotes neurogenesis in the developing spinal cord in a cell cycle-independent manner
    • Lukaszewicz AI, Anderson DJ. Cyclin D1 promotes neurogenesis in the developing spinal cord in a cell cycle-independent manner. Proc Natl Acad Sci USA 2011;108:11632-11637.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 11632-11637
    • Lukaszewicz, A.I.1    Anderson, D.J.2
  • 48
    • 77954185178 scopus 로고    scopus 로고
    • Id proteins facilitate self-renewal and proliferation of neural stem cells
    • Jung S, Park RH, Kim S et al. Id proteins facilitate self-renewal and proliferation of neural stem cells. Stem Cells Dev 2010;19:831-841.
    • (2010) Stem Cells Dev , vol.19 , pp. 831-841
    • Jung, S.1    Park, R.H.2    Kim, S.3
  • 49
    • 0034667554 scopus 로고    scopus 로고
    • Evidence that helix-loop-helix proteins collaborate with retinoblastoma tumor suppressor protein to regulate cortical neurogenesis
    • Toma JG, El-Bizri H, Barnabe-Heider F et al. Evidence that helix-loop-helix proteins collaborate with retinoblastoma tumor suppressor protein to regulate cortical neurogenesis. J Neurosci 2000;20:7648-7656.
    • (2000) J Neurosci , vol.20 , pp. 7648-7656
    • Toma, J.G.1    El-Bizri, H.2    Barnabe-Heider, F.3
  • 50
    • 0028303223 scopus 로고
    • The helix-loop-helix protein Id2 enhances cell proliferation and binds to the retinoblastoma protein
    • Iavarone A, Garg P, Lasorelle A et al. The helix-loop-helix protein Id2 enhances cell proliferation and binds to the retinoblastoma protein. Genes Dev 1994;8:1270-1284.
    • (1994) Genes Dev , vol.8 , pp. 1270-1284
    • Iavarone, A.1    Garg, P.2    Lasorelle, A.3
  • 52
    • 0037305849 scopus 로고    scopus 로고
    • Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system
    • DOI 10.1128/MCB.23.3.1044-1053.2003
    • MacPherson D, Sage J, Crowley D et al. Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system. Mol Cell Biol 2003;23:1044-1053. (Pubitemid 36133520)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.3 , pp. 1044-1053
    • MacPherson, D.1    Sage, J.2    Crowley, D.3    Trumpp, A.4    Bronson, R.T.5    Jacks, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.