메뉴 건너뛰기




Volumn 12, Issue 3, 2013, Pages 403-420

Interactions between oral antineoplastic agents and concomitant medication: A systematic review

Author keywords

Antitumoral agents; Drug interactions; Pharmacodynamics; Pharmacokinetics

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; AMLODIPINE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIMYCOBACTERIAL AGENT; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; BUSULFAN; CALCIUM; CARDIOVASCULAR AGENT; CIPROFLOXACIN; CLARITHROMYCIN; DASATINIB; ERLOTINIB; ERYTHROMYCIN; ESTRAMUSTINE; EVEROLIMUS; FLUOROURACIL; GEFITINIB; IMATINIB; KETOCONAZOLE; METHOTREXATE; METRONIDAZOLE; NAVELBINE; PENICILLIN DERIVATIVE; RITONAVIR; SIMVASTATIN; SORAFENIB; SUNITINIB; UNINDEXED DRUG;

EID: 84876538546     PISSN: 14740338     EISSN: 1744764X     Source Type: Journal    
DOI: 10.1517/14740338.2013.784268     Document Type: Review
Times cited : (18)

References (97)
  • 1
    • 62949147825 scopus 로고    scopus 로고
    • Available from [Last accessed 29 November 2012]
    • European Medicines Agency: summary of product characteristics. Available from: http://www.ema.europa.eu/ema/index.jsp curl=pages/medicines/landing/epar- search.jsp&mid=WC0b01ac058001d124 [Last accessed 29 November 2012]
    • European Medicines Agency: Summary of Product Characteristics
  • 2
    • 84876526138 scopus 로고    scopus 로고
    • Thomson Micromedex Greenwood Village Colorado USA Available from
    • Klasco RK. DRUGDEX-System (electronic version). Thomson Micromedex, Greenwood Village, Colorado, USA. 2012. Available from: http://www.thomsonhc.com [Last accessed 20 Jun 2012]
    • (2012) DRUGDEX-System (Electronic Version)
    • Klasco, R.K.1
  • 4
    • 84876587618 scopus 로고    scopus 로고
    • FDA Drug development and drug interactions (Updated 28 July 2011). Available from [Last accessed 1 September 2012]
    • FDA Drug development and drug interactions. Tables of Substrates, Inhibitors and Inducers (Updated 28 July 2011). Available from: http://www.fda. gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/ DrugInteractionsLabeling/ucm080499. htm [Last accessed 1 September 2012]
    • Tables of Substrates, Inhibitors and Inducers
  • 5
    • 33748065311 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between methotrexate and piperacillin/ tazobactam resulting in prolonged toxic concentrations of methotrexate [9]
    • DOI 10.1093/jac/dkl196
    • Zarychanski R, Wlodarczyk K, Ariano R, Bow E. Pharmacokinetic interaction between methotrexate and piperacillin/tazobactam resulting in prolonged toxic concentrations of methotrexate. J Antimicrob Chemother 2006;58:228-30 (Pubitemid 44295021)
    • (2006) Journal of Antimicrobial Chemotherapy , vol.58 , Issue.1 , pp. 228-230
    • Zarychanski, R.1    Wlodarczyk, K.2    Ariano, R.3    Bow, E.4
  • 8
    • 62949167207 scopus 로고    scopus 로고
    • Evaluation of potential interaction between vinorelbine and clarithromycin
    • Yano R, Tani D, Watanabe K, et al. Evaluation of potential interaction between vinorelbine and clarithromycin. Ann Pharmacother 2009;43:453-8
    • (2009) Ann Pharmacother , vol.43 , pp. 453-458
    • Yano, R.1    Tani, D.2    Watanabe, K.3
  • 10
    • 0242669388 scopus 로고    scopus 로고
    • The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation
    • DOI 10.1038/sj.bmt.1703896
    • Nilsson C, Aschan J, Hentschke P, et al. The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplant 2003;31:429-35 (Pubitemid 36511807)
    • (2003) Bone Marrow Transplantation , vol.31 , Issue.6 , pp. 429-435
    • Nilsson, C.1    Aschan, J.2    Hentschke, P.3    Ringden, O.4    Ljungman, P.5    Hassan, M.6
  • 11
    • 84876523376 scopus 로고    scopus 로고
    • A Drug development and drug interactions. Guidance for industry (Updated February 2012). Available from [Last accessed 3 March 2013]
    • FDA Drug development and drug interactions. Guidance for industry. Drug Interaction Studies-Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations. (Updated February 2012). Available from: http://www.fda.gov/downloads/Drugs/Guidance ComplianceRegulatoryInformation/ Guidances/UCM292362.pdf [Last accessed 3 March 2013]
    • Drug Interaction Studies-Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations
  • 12
    • 33645648696 scopus 로고    scopus 로고
    • Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics
    • Lathia C, Lettieri J, Cihon F, et al. Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics. Cancer Chemother Pharmacol 2006;57:685-92
    • (2006) Cancer Chemother Pharmacol , vol.57 , pp. 685-692
    • Lathia, C.1    Lettieri, J.2    Cihon, F.3
  • 13
    • 37549055433 scopus 로고    scopus 로고
    • Influence of CYP3A4 inhibition on the steady-state pharmacokinetics of imatinib
    • van Erp NP, Gelderblom H, Karlsson MO, et al. Influence of CYP3A4 inhibition on the steady-state pharmacokinetics of imatinib. Clin Cancer Res 2007;13:7394-400
    • (2007) Clin Cancer Res , vol.13 , pp. 7394-7400
    • Van Erp, N.P.1    Gelderblom, H.2    Karlsson, M.O.3
  • 14
    • 76849096060 scopus 로고    scopus 로고
    • Interaction between capecitabine and brivudin in a patient with breast cancer
    • Baena-Cañada JM, Mart́nez MJ, Garća-Olmedo O, et al. Interaction between capecitabine and brivudin in a patient with breast cancer. Nat Rev Clin Oncol 2010;7:55-8
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 55-58
    • Baena-Cañada, J.M.1    Mart́nez, M.J.2    Garća-Olmedo, O.3
  • 16
    • 79954431917 scopus 로고    scopus 로고
    • A phase i open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer
    • Tolcher AW, Appleman LJ, Shapiro GI, et al. A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer. Cancer Chemother Pharmacol 2011;67:751-64
    • (2011) Cancer Chemother Pharmacol , vol.67 , pp. 751-764
    • Tolcher, A.W.1    Appleman, L.J.2    Shapiro, G.I.3
  • 17
    • 72549091339 scopus 로고    scopus 로고
    • Electrocardiographic characterization of the QTc interval in patients with advanced solid tumors: Pharmacokinetic-pharmacodynamic evaluation of sunitinib
    • Bello CL, Mulay M, Huang X, et al. Electrocardiographic characterization of the QTc interval in patients with advanced solid tumors: pharmacokinetic- pharmacodynamic evaluation of sunitinib. Clin Cancer Res 2009;15:7045-52
    • (2009) Clin Cancer Res , vol.15 , pp. 7045-7052
    • Bello, C.L.1    Mulay, M.2    Huang, X.3
  • 18
    • 49249107124 scopus 로고    scopus 로고
    • Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin
    • Veeraputhiran M, Sundermeyer M. Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin. Clin Lung Cancer 2008;9:232-4
    • (2008) Clin Lung Cancer , vol.9 , pp. 232-234
    • Veeraputhiran, M.1    Sundermeyer, M.2
  • 20
    • 84856756147 scopus 로고    scopus 로고
    • The effect of bexarotene on atorvastatin pharmacokinetics: Results from a phase i trial of bexarotene plus chemotherapy in patients with advanced non-small cell lung cancer
    • Wakelee HA, Takimoto CH, Lopez-Anaya A, et al. The effect of bexarotene on atorvastatin pharmacokinetics: results from a phase I trial of bexarotene plus chemotherapy in patients with advanced non-small cell lung cancer. Cancer Chemother Pharmacol 2012;69:563-71
    • (2012) Cancer Chemother Pharmacol , vol.69 , pp. 563-571
    • Wakelee, H.A.1    Takimoto, C.H.2    Lopez-Anaya, A.3
  • 21
    • 84856025247 scopus 로고    scopus 로고
    • Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma
    • Gomo C, Coriat R, Faivre L, et al. Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma. Invest New Drugs 2011;29:1511-14
    • (2011) Invest New Drugs , vol.29 , pp. 1511-1514
    • Gomo, C.1    Coriat, R.2    Faivre, L.3
  • 22
    • 70350093711 scopus 로고    scopus 로고
    • Peripheral neuropathy on imatinib treatment for chronic myeloid leukaemia: Suspected adverse drug interaction with amlodipine
    • Ross DM. Peripheral neuropathy on imatinib treatment for chronic myeloid leukaemia: suspected adverse drug interaction with amlodipine. Intern Med J 2009;39:708
    • (2009) Intern Med J , vol.39 , pp. 708
    • Ross, D.M.1
  • 27
    • 78650994740 scopus 로고    scopus 로고
    • Effects of imatinib mesylate on the pharmacokinetics of paracetamol (paracetamol) in Korean patients with chronic myelogenous leukaemia
    • Kim DW, Tan EY, Jin Y, et al. Effects of imatinib mesylate on the pharmacokinetics of paracetamol (paracetamol) in Korean patients with chronic myelogenous leukaemia. Br J Clin Pharmacol 2011;71:199-206
    • (2011) Br J Clin Pharmacol , vol.71 , pp. 199-206
    • Kim, D.W.1    Tan, E.Y.2    Jin, Y.3
  • 28
    • 16644373437 scopus 로고    scopus 로고
    • Methotrexate-loxoprofen interaction: Involvement of human organic anion transporters hOAT1 and hOAT3
    • Uwai Y, Taniguchi R, Motohashi H, et al. Methotrexate-loxoprofen interaction: involvement of human organic anion transporters hOAT1 and hOAT3. Drug Metab Pharmacokinet 2004;19:369-74
    • (2004) Drug Metab Pharmacokinet , vol.19 , pp. 369-374
    • Uwai, Y.1    Taniguchi, R.2    Motohashi, H.3
  • 29
  • 30
    • 0024843449 scopus 로고
    • Serious methotrexate toxicity caused by interaction with ibuprofen
    • Cassano WF. Serious methotrexate toxicity caused by interaction with ibuprofen. Am J Pediatr Hematol Oncol 1989;11:481-2 (Pubitemid 20020010)
    • (1989) American Journal of Pediatric Hematology/Oncology , vol.11 , Issue.4 , pp. 481-482
    • Cassano, W.F.1
  • 31
    • 0025125626 scopus 로고
    • Lack of significant interaction between low dose methotrexate and ibuprofen or flurbiprofen in patients with arthritis
    • Skeith KJ, Russell AS, Jamali F, et al. Lack of significant interaction between low dose methotrexate and ibuprofen or flurbiprofen in patients with arthritis. J Rheumatol 1990;17:1008-10 (Pubitemid 20278014)
    • (1990) Journal of Rheumatology , vol.17 , Issue.8 , pp. 1008-1010
    • Skeith, K.J.1    Russell, A.S.2    Jamali, F.3    Coates, J.4    Friedman, H.5
  • 32
    • 63849243041 scopus 로고    scopus 로고
    • Effects of ketoconazole and carbamazepine on lapatinib pharmacokinetics in healthy subjects
    • Smith DA, Koch KM, Arya N, et al. Effects of ketoconazole and carbamazepine on lapatinib pharmacokinetics in healthy subjects. Br J Clin Pharmacol 2009;67:421-6
    • (2009) Br J Clin Pharmacol , vol.67 , pp. 421-426
    • Smith, D.A.1    Koch, K.M.2    Arya, N.3
  • 34
    • 79751535045 scopus 로고    scopus 로고
    • Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: Results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma
    • Reardon DA, Vredenburgh JJ, Desjardins A, et al. Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma. J Neurooncol 2011;101:57-66
    • (2011) J Neurooncol , vol.101 , pp. 57-66
    • Reardon, D.A.1    Vredenburgh, J.J.2    Desjardins, A.3
  • 35
    • 58149125873 scopus 로고    scopus 로고
    • Influence of enzyme-inducing antiepileptic drugs on trough level of imatinib in glioblastoma patients
    • Pursche S, Schleyer E, von Bonin M, et al. Influence of enzyme-inducing antiepileptic drugs on trough level of imatinib in glioblastoma patients. Curr Clin Pharmacol 2008;3:198-203
    • (2008) Curr Clin Pharmacol , vol.3 , pp. 198-203
    • Pursche, S.1    Schleyer, E.2    Von Bonin, M.3
  • 36
    • 0042234101 scopus 로고    scopus 로고
    • Phenytoin toxicity due to fluoropyrimidines (5FU/capecitabine): Three case reports
    • DOI 10.1038/sj.bjc.6601137
    • Brickell K, Porter D, Thompson P. Phenytoin toxicity due to fluoropyrimidines (5FU/capecitabine): three case reports. Br J Cancer 2003;89:615-16 (Pubitemid 37076161)
    • (2003) British Journal of Cancer , vol.89 , Issue.4 , pp. 615-616
    • Brickell, K.1    Porter, D.2    Thompson, P.3
  • 37
    • 34548009373 scopus 로고    scopus 로고
    • Significant drug interaction: Phenytoin toxicity due to erlotinib
    • DOI 10.1016/j.lungcan.2007.02.011, PII S0169500207001250
    • Grenader T, Gipps M, Shavit L, Gabizon A. Significant drug interaction: phenytoin toxicity due to erlotinib. Lung Cancer 2007;57:404-6 (Pubitemid 47285413)
    • (2007) Lung Cancer , vol.57 , Issue.3 , pp. 404-406
    • Grenader, T.1    Gipps, M.2    Shavit, L.3    Gabizon, A.4
  • 38
    • 79958754972 scopus 로고    scopus 로고
    • Concurrent use of tamoxifen with CYP2D6 inhibitors and the risk of breast cancer recurrence
    • Azoulay L, Dell'Aniello S, Huiart L, et al. Concurrent use of tamoxifen with CYP2D6 inhibitors and the risk of breast cancer recurrence. Breast Cancer Res Treat 2011;126:695-703
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 695-703
    • Azoulay, L.1    Dell'Aniello, S.2    Huiart, L.3
  • 39
    • 49549120842 scopus 로고    scopus 로고
    • Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram
    • Lash TL, Pedersen L, Cronin-Fenton D, et al. Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram. Br J Cancer 2008;99:616-21
    • (2008) Br J Cancer , vol.99 , pp. 616-621
    • Lash, T.L.1    Pedersen, L.2    Cronin-Fenton, D.3
  • 40
    • 58849087666 scopus 로고    scopus 로고
    • Clinical implications of CYP2D6 genotyping in tamoxifen treatment for breast cancer
    • Dezentjé VO, Guchelaar HJ, Nortier JW, et al. Clinical implications of CYP2D6 genotyping in tamoxifen treatment for breast cancer. Clin Cancer Res 2009;15:15-21
    • (2009) Clin Cancer Res , vol.15 , pp. 15-21
    • Dezentjé, V.O.1    Guchelaar, H.J.2    Nortier, J.W.3
  • 41
    • 74549184178 scopus 로고    scopus 로고
    • Risk of breast cancer recurrence in women initiating tamoxifen with CYP2D6 inhibitors [abstract CRA508]
    • Aubert RE, Stanek EJ, Yao J, et al. Risk of breast cancer recurrence in women initiating tamoxifen with CYP2D6 inhibitors [abstract CRA508]. J Clin Oncol 2009;27:S18
    • (2009) J Clin Oncol , vol.27
    • Aubert, R.E.1    Stanek, E.J.2    Yao, J.3
  • 42
    • 74549144558 scopus 로고    scopus 로고
    • Interactions between tamoxifen and antidepressants via cytochrome P450 2D6
    • Desmarais JE, Looper KJ. Interactions between tamoxifen and antidepressants via cytochrome P450 2D6. J Clin Psychiatry 2009;70:1688-97
    • (2009) J Clin Psychiatry , vol.70 , pp. 1688-1697
    • Desmarais, J.E.1    Looper, K.J.2
  • 43
    • 67049154407 scopus 로고    scopus 로고
    • Phase i study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects
    • Eley T, Luo FR, Agrawal S, et al. Phase I study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects. J Clin Pharmacol 2009;49:700-9
    • (2009) J Clin Pharmacol , vol.49 , pp. 700-709
    • Eley, T.1    Luo, F.R.2    Agrawal, S.3
  • 44
    • 77955807815 scopus 로고    scopus 로고
    • Effect of the proton pump inhibitor esomeprazole on the oral absorption and pharmacokinetics of nilotinib
    • Yin OQ, Gallagher N, Fischer D, et al. Effect of the proton pump inhibitor esomeprazole on the oral absorption and pharmacokinetics of nilotinib. J Clin Pharmacol 2010;50:960-7
    • (2010) J Clin Pharmacol , vol.50 , pp. 960-967
    • Yin, O.Q.1    Gallagher, N.2    Fischer, D.3
  • 45
    • 82455192303 scopus 로고    scopus 로고
    • Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: A phase I/II pharmacokinetic interaction study
    • Flaherty KT, Lathia C, Frye RF, et al. Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study. Cancer Chemother Pharmacol 2011;68:1111-18
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 1111-1118
    • Flaherty, K.T.1    Lathia, C.2    Frye, R.F.3
  • 46
    • 84866526227 scopus 로고    scopus 로고
    • Concurrent use of proton pump inhibitors or H2 blockers did not adversely affect nilotinib efficacy in patients with chronic myeloid leukemia
    • Yin OQ, Giles FJ, Baccarani M, et al. Concurrent use of proton pump inhibitors or H2 blockers did not adversely affect nilotinib efficacy in patients with chronic myeloid leukemia. Cancer Chemother Pharmacol 2012;70:345-50
    • (2012) Cancer Chemother Pharmacol , vol.70 , pp. 345-350
    • Yin, O.Q.1    Giles, F.J.2    Baccarani, M.3
  • 47
    • 82555192635 scopus 로고    scopus 로고
    • Should the concomitant use of erlotinib and acid-reducing agents be avoided the drug interaction between erlotinib and acid-reducing agents
    • Duong S, Leung M. Should the concomitant use of erlotinib and acid-reducing agents be avoided The drug interaction between erlotinib and acid-reducing agents. J Oncol Pharm Pract 2011;17:448-52
    • (2011) J Oncol Pharm Pract , vol.17 , pp. 448-452
    • Duong, S.1    Leung, M.2
  • 48
    • 77954832203 scopus 로고    scopus 로고
    • Aprepitant for erlotinib-induced pruritus
    • Vincenzi B, Tonini G, Santini D. Aprepitant for erlotinib-induced pruritus. N Engl J Med 2010;363:397-8
    • (2010) N Engl J Med , vol.363 , pp. 397-398
    • Vincenzi, B.1    Tonini, G.2    Santini, D.3
  • 49
    • 0018872133 scopus 로고
    • The pharmacokinetics of cyclophosphamide in man after treatment with allopurinol
    • Witten J, Frederiksen PL, Mouridsen HT. The pharmacokinetics of cyclophosphamide in man after treatment with allopurinol. Acta Pharmacol Toxicol 1980;46:392-4 (Pubitemid 10106143)
    • (1980) Acta Pharmacologica et Toxicologica , vol.46 , Issue.5 , pp. 392-394
    • Witten, J.1    Frederiksen, P.L.2    Mouridsen, H.T.3
  • 50
    • 0016384109 scopus 로고
    • Allopurinol and cytotoxic drugs Interaction in relation to bone marrow depression
    • Boston Collaborative Drug Surveillence Program
    • Boston Collaborative Drug Surveillence Program. Allopurinol and cytotoxic drugs. Interaction in relation to bone marrow depression. JAMA 1974;227:1036
    • (1974) JAMA , vol.227 , pp. 1036
  • 51
    • 84944373799 scopus 로고
    • Evaluation of bone marrow toxic reaction in patients treated with allopurinol
    • DOI 10.1001/jama.247.3.334
    • Stolbach L, Begg C, Bennett JM, et al. Evaluation of bone marrow toxic reaction in patients treated with allopurinol. JAMA 1982;247:334-6 (Pubitemid 12203020)
    • (1982) Journal of the American Medical Association , vol.247 , Issue.3 , pp. 334-336
    • Stolbach, L.1    Begg, C.2    Bennett, J.M.3
  • 54
    • 79956044510 scopus 로고    scopus 로고
    • Dutch Society of Clinical Pharmacology and Biopharmacy (NVKF&B) Consensus-based evaluation of clinical significance and management of anticancer drug interactions
    • Scientific Institute for Dutch Pharmacists (WINAp); Dutch Society for Medical Oncology (NVMO)
    • Jansman FG, Reyners AK, van Roon EN, et al. Scientific Institute for Dutch Pharmacists (WINAp); Dutch Society for Medical Oncology (NVMO); Dutch Society of Clinical Pharmacology and Biopharmacy (NVKF&B). Consensus-based evaluation of clinical significance and management of anticancer drug interactions. Clin Ther 2011;33:305-14
    • (2011) Clin Ther , vol.33 , pp. 305-314
    • Jansman, F.G.1    Reyners, A.K.2    Van Roon, E.N.3
  • 55
    • 0141615878 scopus 로고    scopus 로고
    • Combined oral cyclosporin and methotrexate therapy in patients with rheumatoid arthritis elevates methotrexate levels and reduces 7-hydroxymethotrexate levels when compared with methotrexate alone
    • DOI 10.1093/rheumatology/keg277
    • Fox RI, Morgan SL, Smith HT, et al. Combined oral cyclosporin and methotrexate therapy in patients with rheumatoid arthritis elevates methotrexate levels and reduces 7-hydroxymethotrexate levels when compared with methotrexate alone. Rheumatology 2003;42:989-94 (Pubitemid 37220969)
    • (2003) Rheumatology , vol.42 , Issue.8 , pp. 989-994
    • Fox, R.I.1    Morgan, S.L.2    Smith, H.T.3    Robbins, B.A.4    Choc, M.G.5    Baggott, J.E.6
  • 56
    • 0036138190 scopus 로고    scopus 로고
    • Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: A clinically relevant pharmacokinetic interaction
    • DOI 10.1177/0091270002042001011
    • Kovarik JM, Kalbag J, Figueiredo J, et al. Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: a clinically relevant pharmacokinetic interaction. J Clin Pharmacol 2002;42:95-9 (Pubitemid 34038374)
    • (2002) Journal of Clinical Pharmacology , vol.42 , Issue.1 , pp. 95-99
    • Kovarik, J.M.1    Kalbag, J.2    Figueiredo, J.3    Rouilly, M.4    O'Bannon, L.F.5    Rordorf, C.6
  • 58
    • 84875532963 scopus 로고    scopus 로고
    • Renal dysfunction in a renal transplant patient treated concurrently with cyclosporine and imatinib
    • Mulder KE, Egorin MJ, Sawyer MB. Renal dysfunction in a renal transplant patient treated concurrently with cyclosporine and imatinib. Invest New Drugs 2012;30:2400-2
    • (2012) Invest New Drugs , vol.30 , pp. 2400-2402
    • Mulder, K.E.1    Egorin, M.J.2    Sawyer, M.B.3
  • 60
    • 70350048926 scopus 로고    scopus 로고
    • Impact of OATP transporters on pharmacokinetics
    • Kalliokoski A, Niemi M. Impact of OATP transporters on pharmacokinetics. Br J Pharmacol 2009;158:693-705
    • (2009) Br J Pharmacol , vol.158 , pp. 693-705
    • Kalliokoski, A.1    Niemi, M.2
  • 61
    • 84858820185 scopus 로고    scopus 로고
    • Renal drug-drug interactions: What we have learned and where we are going
    • Lepist EI, Ray AS. Renal drug-drug interactions: what we have learned and where we are going. Expert Opin Drug Metab Toxicol 2012;8:433-48
    • (2012) Expert Opin Drug Metab Toxicol , vol.8 , pp. 433-448
    • Lepist, E.I.1    Ray, A.S.2
  • 62
    • 84876529850 scopus 로고    scopus 로고
    • US Foos and Drug Administration: summary of product characteristics. Available from fda/index.cfm [Last accessed 03 March 2013]
    • US Foos and Drug Administration: summary of product characteristics. Available from: http://www.accessdata. fda.gov/scripts/cder/drugsatfda/index.cfm [Last accessed 03 March 2013]
  • 64
    • 77949369418 scopus 로고    scopus 로고
    • Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors
    • Johnson FM, Agrawal S, Burris H, et al. Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors. Cancer 2010;116:1582-91
    • (2010) Cancer , vol.116 , pp. 1582-1591
    • Johnson, F.M.1    Agrawal, S.2    Burris, H.3
  • 65
    • 38049054403 scopus 로고    scopus 로고
    • The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: Computer-based simulation (SimCYP-) predicts in vivo metabolic inhibition
    • Rakhit A, Pantze MP, Fettner S, et al. The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP-) predicts in vivo metabolic inhibition. Eur J Clin Pharmacol 2008;64:31-41
    • (2008) Eur J Clin Pharmacol , vol.64 , pp. 31-41
    • Rakhit, A.1    Pantze, M.P.2    Fettner, S.3
  • 68
    • 78650725834 scopus 로고    scopus 로고
    • In vitro cytochrome P450-mediated metabolism of exemestane
    • Kamdem LK, Flockhart DA, Desta Z. In vitro cytochrome P450-mediated metabolism of exemestane. Drug Metab Dispos 2011;39:98-105
    • (2011) Drug Metab Dispos , vol.39 , pp. 98-105
    • Kamdem, L.K.1    Flockhart, D.A.2    Desta, Z.3
  • 71
    • 84857058887 scopus 로고    scopus 로고
    • Drug interaction between lenalidomide and itraconazole
    • Takahashi N, Miura M, Kameoka Y, et al. Drug interaction between lenalidomide and itraconazole. Am J Hematol 2012;87:338-9
    • (2012) Am J Hematol , vol.87 , pp. 338-339
    • Takahashi, N.1    Miura, M.2    Kameoka, Y.3
  • 72
    • 33646437882 scopus 로고    scopus 로고
    • The effect of ketoconazole a potent CYP3A4 inhibitor on SU011248 pharmacokinetics in caucasian and Asian healthy subjects [abstr 553]
    • Washington C, Eli M, Bello C, et al. The effect of ketoconazole, a potent CYP3A4 inhibitor, on SU011248 pharmacokinetics in caucasian and Asian healthy subjects [abstr no. 553]. Proc Am Soc Clin Oncol 2003;22
    • (2003) Proc Am Soc Clin Oncol , vol.22
    • Washington, C.1    Eli, M.2    Bello, C.3
  • 74
    • 0038559875 scopus 로고    scopus 로고
    • Interaction of all-trans-retinoic acid with fluconazole in acute promyelocytic leukemia
    • DOI 10.1097/00043426-200305000-00010
    • Vanier KL, Mattiussi AJ, Johnston DL. Interaction of all-trans-retinoic acid with fluconazole in acute promyelocytic leukemia. J Pediatr Hematol Oncol 2003;25:403-4 (Pubitemid 36569973)
    • (2003) Journal of Pediatric Hematology/Oncology , vol.25 , Issue.5 , pp. 403-404
    • Vanier, K.L.1    Mattiussi, A.J.2    Johnston, D.L.3
  • 75
    • 32144432801 scopus 로고    scopus 로고
    • Hypercalcemia due to all trans retinoic acid in the treatment of acute promyelocytic leukemia potentiated by voriconazole
    • DOI 10.1080/10428190500235298, PII P92594440174121
    • Bennett MT, Sirrs S, Yeung JK, Smith CA. Hypercalcemia due to all trans retinoic acid in the treatment of acute promyelocytic leukemia potentiated by voriconazole. Leuk Lymphoma 2005;46:1829-31 (Pubitemid 43203121)
    • (2005) Leukemia and Lymphoma , vol.46 , Issue.12 , pp. 1829-1831
    • Bennett, M.T.1    Sirrs, S.2    Yeung, J.K.3    Smith, C.A.4
  • 76
    • 79952279665 scopus 로고    scopus 로고
    • Pseudotumor cerebri due to potentiation of all-trans retinoic acid by voriconazole
    • Dixon KS, Hassoun A. Pseudotumor cerebri due to potentiation of all-trans retinoic acid by voriconazole. J Am Pharm Assoc 2010;50:742-4
    • (2010) J Am Pharm Assoc , vol.50 , pp. 742-744
    • Dixon, K.S.1    Hassoun, A.2
  • 78
    • 28444452658 scopus 로고    scopus 로고
    • A drug-drug interaction study to evaluate the effect of rifampicin on the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib in healthy subjects [abstract 548]
    • Abbas R, Fettner S, Riek M, et al. A drug-drug interaction study to evaluate the effect of rifampicin on the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib in healthy subjects [abstract 548]. Proc Am Soc Clin Oncol 2003;22:137
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 137
    • Abbas, R.1    Fettner, S.2    Riek, M.3
  • 81
    • 60549098640 scopus 로고    scopus 로고
    • Sorafenib: A review of its use in advanced hepatocellular carcinoma
    • Keating GM, Santoro A. Sorafenib: a review of its use in advanced hepatocellular carcinoma. Drugs 2009;69:223-40
    • (2009) Drugs , vol.69 , pp. 223-240
    • Keating, G.M.1    Santoro, A.2
  • 82
    • 80051560737 scopus 로고    scopus 로고
    • Effect of rifampin on the pharmacokinetics of sunitinib malate (SU11248) in Caucasian and Japanese populations [abstract 430]
    • Paris
    • Bello C, Houk B, Sherman L, et al. Effect of rifampin on the pharmacokinetics of sunitinib malate (SU11248) in Caucasian and Japanese populations [abstract 430]. 13th European Cancer Conference; Paris; 2005
    • (2005) 13th European Cancer Conference
    • Bello, C.1    Houk, B.2    Sherman, L.3
  • 84
    • 0034858208 scopus 로고    scopus 로고
    • The effect of anastrozole on the single-dose pharmacokinetics and anticoagulant activity of warfarin in healthy volunteers
    • DOI 10.1046/j.1365-2125.2001.01358.x
    • Yates RA, Wong J, Seiberling M, et al. The effect of anastrozole on the single-dose pharmacokinetics and anticoagulant activity of warfarin in healthy volunteers. J Clin Pharmacol 2001;51:429-35 (Pubitemid 32852980)
    • (2001) British Journal of Clinical Pharmacology , vol.51 , Issue.5 , pp. 429-435
    • Yates, R.A.1    Wong, J.2    Seiberling, M.3    Merz, M.4    Marz, W.5    Nauck, M.6
  • 85
    • 23944472628 scopus 로고    scopus 로고
    • Capecitabine-warfarin interaction
    • DOI 10.1345/aph.1G153
    • Janney LM, Waterbury NV. Capecitabine-Warfarin Interaction. Ann Pharmacother 2005;39:1546-51 (Pubitemid 41197140)
    • (2005) Annals of Pharmacotherapy , vol.39 , Issue.9 , pp. 1546-1551
    • Janney, L.M.1    Waterbury, N.V.2
  • 86
    • 0021919778 scopus 로고
    • Possible interactions between warfarin and antineoplastic drugs
    • Seifter EJ, Brooks BJ. Jr, Urba WJ. Possible interactions between warfarin and antineoplastic drugs. Cancer Treat Rep 1985;69:244-5 (Pubitemid 15170473)
    • (1985) Cancer Treatment Reports , vol.69 , Issue.2 , pp. 244-245
    • Seifter, E.J.1    Brooks Jr., B.J.2    Urba, W.J.3
  • 87
    • 84876588238 scopus 로고    scopus 로고
    • Eulexin-(flutamide) tablets [product Information]. Schering Corporation; Kenilworth, NJ 1999
    • Eulexin-(flutamide) tablets [product Information]. Schering Corporation; Kenilworth, NJ: 1999
  • 88
    • 67651089848 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia
    • Quintás-Cardama A, Han X, Kantarjian H, et al. Tyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemia. Blood 2009;114:261-3
    • (2009) Blood , vol.114 , pp. 261-263
    • Quintás-Cardama, A.1    Han, X.2    Kantarjian, H.3
  • 89
    • 69249185747 scopus 로고    scopus 로고
    • Effect of gefitinib on warfarin antithrombotic activity
    • Arai S, Mitsufuji H, Nishii Y, et al. Effect of gefitinib on warfarin antithrombotic activity. Int J Clin Oncol 2009;14:332-6
    • (2009) Int J Clin Oncol , vol.14 , pp. 332-336
    • Arai, S.1    Mitsufuji, H.2    Nishii, Y.3
  • 90
    • 79952031071 scopus 로고    scopus 로고
    • Elevated international normalized ratio associated with concomitant warfarin and erlotinib
    • Thomas KS, Billingsley A, Amarshi N, et al. Elevated international normalized ratio associated with concomitant warfarin and erlotinib. Am J Health Syst Pharm 2010;67:1426-9
    • (2010) Am J Health Syst Pharm , vol.67 , pp. 1426-1429
    • Thomas, K.S.1    Billingsley, A.2    Amarshi, N.3
  • 91
    • 73649094145 scopus 로고    scopus 로고
    • Elevated International Normalized Ratio associated with concurrent use of sorafenib and warfarin
    • Moretti LV, Montalvo RO. Elevated International Normalized Ratio associated with concurrent use of sorafenib and warfarin. Am J Health Syst Pharm 2009;66:2123-5
    • (2009) Am J Health Syst Pharm , vol.66 , pp. 2123-2125
    • Moretti, L.V.1    Montalvo, R.O.2
  • 92
    • 77953611663 scopus 로고    scopus 로고
    • Concomitant use of imatinib and warfarin in chronic phase chronic myeloid leukemia patients does not interfere with drug efficacy
    • Breccia M, Santopietro M, Logisci G, et al. Concomitant use of imatinib and warfarin in chronic phase chronic myeloid leukemia patients does not interfere with drug efficacy. Leuk Res 2010;34:e224-5
    • (2010) Leuk Res , vol.34
    • Breccia, M.1    Santopietro, M.2    Logisci, G.3
  • 93
    • 79751474810 scopus 로고    scopus 로고
    • Effects of nilotinib on single-dose warfarin pharmacokinetics and pharmacodynamics: A randomized, single-blind, two-period crossover study in healthy subjects
    • Yin OQ, Gallagher N, Fischer D, et al. Effects of nilotinib on single-dose warfarin pharmacokinetics and pharmacodynamics: a randomized, single-blind, two-period crossover study in healthy subjects. Clin Drug Investig 2011;31:169-79
    • (2011) Clin Drug Investig , vol.31 , pp. 169-179
    • Yin, O.Q.1    Gallagher, N.2    Fischer, D.3
  • 96
    • 70049097234 scopus 로고    scopus 로고
    • Effect of a proton pump inhibitor on the pharmacokinetics of imatinib
    • Egorin MJ, Shah DD, Christner SM, et al. Effect of a proton pump inhibitor on the pharmacokinetics of imatinib. Br J Clin Pharmacol 2009;68:370-4
    • (2009) Br J Clin Pharmacol , vol.68 , pp. 370-374
    • Egorin, M.J.1    Shah, D.D.2    Christner, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.