메뉴 건너뛰기




Volumn 133, Issue 5, 2013, Pages 1269-1277

Oncogenic B-RAF V600E signaling induces the T-Box3 transcriptional repressor to repress E-cadherin and enhance melanoma cell invasion

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; CELL ADHESION MOLECULE; T BOX 3 TRANSCRIPTIONAL REPRESSOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 84876525324     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.421     Document Type: Article
Times cited : (45)

References (41)
  • 1
    • 0035880957 scopus 로고    scopus 로고
    • Prognostic factors analysis of 17, 600 melanoma patients: Validation of the American Joint Committee on Cancer melanoma staging system
    • Balch CM, Soong SJ, Gershenwald JE et al. (2001) Prognostic factors analysis of 17, 600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol 19:3622-34
    • (2001) J Clin Oncol , vol.19 , pp. 3622-3634
    • Balch, C.M.1    Soong, S.J.2    Gershenwald, J.E.3
  • 2
    • 0030986873 scopus 로고    scopus 로고
    • Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome
    • Bamshad M, Lin RC, Law DJ et al. (1997) Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Nat Genet 16:311-5
    • (1997) Nat Genet , vol.16 , pp. 311-315
    • Bamshad, M.1    Lin, R.C.2    Law, D.J.3
  • 3
    • 77956571967 scopus 로고    scopus 로고
    • Correlation between the BRAF V600E mutation and tumor invasiveness in papillary thyroid carcinomas smaller than 20 millimeters: Analysis of 1060 cases
    • Basolo F, Torregrossa L, Giannini R et al. (2010) Correlation between the BRAF V600E mutation and tumor invasiveness in papillary thyroid carcinomas smaller than 20 millimeters: analysis of 1060 cases. J Clin Endocrinol Metab 95:4197-205
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 4197-4205
    • Basolo, F.1    Torregrossa, L.2    Giannini, R.3
  • 4
    • 77954761299 scopus 로고    scopus 로고
    • Oncogenic B-RAF(V600E) promotes anchorage-independent survival of human melanocytes
    • Becker TM, Philipsz S, Scurr LL et al. (2010) Oncogenic B-RAF(V600E) promotes anchorage-independent survival of human melanocytes. J Invest Dermatol 130:2144-7
    • (2010) J Invest Dermatol , vol.130 , pp. 2144-2147
    • Becker, T.M.1    Philipsz, S.2    Scurr, L.L.3
  • 5
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesench-ymal transitions: A comparison with Snail and E47 repressors
    • Bolos V, Peinado H, Perez-Moreno MA et al. (2003) The transcription factor Slug represses E-cadherin expression and induces epithelial to mesench-ymal transitions: a comparison with Snail and E47 repressors. J Cell Sci 116:499-511
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3
  • 6
    • 78049305326 scopus 로고    scopus 로고
    • Genetic and morphologic features for melanoma classification
    • Broekaert SM, Roy R, Okamoto I et al. (2010) Genetic and morphologic features for melanoma classification. Pigment Cell Melanoma Res 23:763-70
    • (2010) Pigment Cell Melanoma Res , vol.23 , pp. 763-770
    • Broekaert, S.M.1    Roy, R.2    Okamoto, I.3
  • 7
    • 0037155231 scopus 로고    scopus 로고
    • TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence
    • Brummelkamp TR, Kortlever RM, Lingbeek M et al. (2002) TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence. J Biol Chem 277:6567-72
    • (2002) J Biol Chem , vol.277 , pp. 6567-6572
    • Brummelkamp, T.R.1    Kortlever, R.M.2    Lingbeek, M.3
  • 8
    • 33749832543 scopus 로고    scopus 로고
    • Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein
    • Brummer T, Martin P, Herzog S et al. (2006) Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein. Oncogene 25:6262-76
    • (2006) Oncogene , vol.25 , pp. 6262-6276
    • Brummer, T.1    Martin, P.2    Herzog, S.3
  • 9
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, Perez-Moreno MA, Rodrigo I et al. (2000) The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2:76-83
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3
  • 10
    • 0345599013 scopus 로고    scopus 로고
    • Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK
    • Conacci-Sorrell M, Simcha I, Ben-Yedidia T et al. (2003) Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK. J Cell Biol 163:847-57
    • (2003) J Cell Biol , vol.163 , pp. 847-857
    • Conacci-Sorrell, M.1    Simcha, I.2    Ben-Yedidia, T.3
  • 11
    • 84861083983 scopus 로고    scopus 로고
    • Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial
    • Falchook GS, Long GV, Kurzrock R et al. (2012) Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 379:1893-901
    • (2012) Lancet , vol.379 , pp. 1893-1901
    • Falchook, G.S.1    Long, G.V.2    Kurzrock, R.3
  • 12
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • Flaherty KT, Puzanov I, Kim KB et al. (2010) Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 363:809-19
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 13
    • 19544362066 scopus 로고    scopus 로고
    • Adhesion, migration and communication in melanocytes and melanoma
    • Haass NK, Smalley KS, Li L et al. (2005) Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Res 18:150-9
    • (2005) Pigment Cell Res , vol.18 , pp. 150-159
    • Haass, N.K.1    Smalley, K.S.2    Li, L.3
  • 14
    • 77952779168 scopus 로고    scopus 로고
    • The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence
    • Haferkamp S, Tran SL, Becker TM et al. (2009) The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence. Aging 1:542-56
    • (2009) Aging , vol.1 , pp. 542-556
    • Haferkamp, S.1    Tran, S.L.2    Becker, T.M.3
  • 15
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra KM, Chen DY, Fearon ER (2002) The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 62:1613-8
    • (2002) Cancer Res , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 16
    • 3442894137 scopus 로고    scopus 로고
    • Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas
    • Hoek K, Rimm DL, Williams KR et al. (2004) Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res 64:5270-82
    • (2004) Cancer Res , vol.64 , pp. 5270-5282
    • Hoek, K.1    Rimm, D.L.2    Williams, K.R.3
  • 17
    • 43549088089 scopus 로고    scopus 로고
    • TBX3 and its splice variant TBX3+exon 2a are functionally similar
    • Hoogaars WM, Barnett P, Rodriguez M et al. (2008) TBX3 and its splice variant TBX3+exon 2a are functionally similar. Pigment Cell Melanoma Res 21:379-87
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 379-387
    • Hoogaars, W.M.1    Barnett, P.2    Rodriguez, M.3
  • 18
    • 0033838767 scopus 로고    scopus 로고
    • E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors
    • Hsu MY, Meier FE, Nesbit M et al. (2000) E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am J Pathol 156:1515-25
    • (2000) Am J Pathol , vol.156 , pp. 1515-1525
    • Hsu, M.Y.1    Meier, F.E.2    Nesbit, M.3
  • 19
    • 24644503206 scopus 로고    scopus 로고
    • S100A4 expression with reduced E-cadherin expression predicts distant metastasis of human malignant melanoma cell lines in the NOD/SCID/gammaCnull (NOG) mouse model
    • Ikoma N, Yamazaki H, Abe Y et al. (2005) S100A4 expression with reduced E-cadherin expression predicts distant metastasis of human malignant melanoma cell lines in the NOD/SCID/gammaCnull (NOG) mouse model. Oncol Rep 14:633-7
    • (2005) Oncol Rep , vol.14 , pp. 633-637
    • Ikoma, N.1    Yamazaki, H.2    Abe, Y.3
  • 20
    • 34248630805 scopus 로고    scopus 로고
    • Confirmation of a BRAF mutation-associated gene expression signature in melanoma
    • Johansson P, Pavey S, Hayward N (2007) Confirmation of a BRAF mutation-associated gene expression signature in melanoma. Pigment Cell Res 20:216-21
    • (2007) Pigment Cell Res , vol.20 , pp. 216-221
    • Johansson, P.1    Pavey, S.2    Hayward, N.3
  • 21
    • 79960381628 scopus 로고    scopus 로고
    • Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFbeta signaling
    • Knauf JA, Sartor MA, Medvedovic M et al. (2011) Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFbeta signaling. Oncogene 30:3153-62
    • (2011) Oncogene , vol.30 , pp. 3153-3162
    • Knauf, J.A.1    Sartor, M.A.2    Medvedovic, M.3
  • 22
    • 42149194973 scopus 로고    scopus 로고
    • Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma
    • Kreizenbeck GM, Berger AJ, Subtil A et al. (2008) Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma. Cancer Epidemiol Biomarkers Prev 17:949-58
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 949-958
    • Kreizenbeck, G.M.1    Berger, A.J.2    Subtil, A.3
  • 23
    • 84862190439 scopus 로고    scopus 로고
    • E-cadherin cell-cell communication in melanogenesis and during development of malignant melanoma
    • Kuphal S, Bosserhoff AK (2011) E-cadherin cell-cell communication in melanogenesis and during development of malignant melanoma. Arch Biochem Biophys 524:43-7
    • (2011) Arch Biochem Biophys , vol.524 , pp. 43-47
    • Kuphal, S.1    Bosserhoff, A.K.2
  • 24
    • 34447521979 scopus 로고    scopus 로고
    • Tbx3, a transcriptional factor, involves in proliferation and osteogenic differentiation of human adipose stromal cells
    • Lee HS, Cho HH, Kim HK et al. (2007) Tbx3, a transcriptional factor, involves in proliferation and osteogenic differentiation of human adipose stromal cells. Mol Cell Biochem 296:129-36
    • (2007) Mol Cell Biochem , vol.296 , pp. 129-136
    • Lee, H.S.1    Cho, H.H.2    Kim, H.K.3
  • 25
    • 79952845386 scopus 로고    scopus 로고
    • The role of B-RAF mutations in melanoma and the induction of EMT via dysregulation of the NF-kappaB/Snail/RKIP/PTEN circuit
    • Lin K, Baritaki S, Militello L et al. (2010) The role of B-RAF mutations in melanoma and the induction of EMT via dysregulation of the NF-kappaB/Snail/RKIP/PTEN circuit. Genes Cancer 1:409-20
    • (2010) Genes Cancer , vol.1 , pp. 409-420
    • Lin, K.1    Baritaki, S.2    Militello, L.3
  • 26
    • 78649458007 scopus 로고
    • TBX2 and TBX3: The special value for anticancer drug targets
    • Lu J, Li XP, Dong Q et al. (2010) TBX2 and TBX3: the special value for anticancer drug targets. Biochim Biophys Acta 1806:268-74
    • (1806) Biochim Biophys Acta , pp. 268-274
    • Lu, J.1    Li, X.P.2    Dong, Q.3
  • 27
    • 34249785078 scopus 로고    scopus 로고
    • Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis
    • Minoo P, Moyer MP, Jass JR (2007) Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis. J Pathol 212:124-33
    • (2007) J Pathol , vol.212 , pp. 124-133
    • Minoo, P.1    Moyer, M.P.2    Jass, J.R.3
  • 28
    • 79551485331 scopus 로고    scopus 로고
    • TPA-induced upregulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration
    • Mowla S, Pinnock R, Leaner VD et al. (2010) TPA-induced upregulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration. Biochem J 433:145-53
    • (2010) Biochem J , vol.433 , pp. 145-153
    • Mowla, S.1    Pinnock, R.2    Leaner, V.D.3
  • 29
    • 77953766335 scopus 로고    scopus 로고
    • B-Raf(V600E) and thrombos-pondin-1 promote thyroid cancer progression
    • Nucera C, Porrello A, Antonello ZA et al. (2010) B-Raf(V600E) and thrombos-pondin-1 promote thyroid cancer progression. Proc Natl Acad Sci USA 107:10649-54
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10649-10654
    • Nucera, C.1    Porrello, A.2    Antonello, Z.A.3
  • 30
    • 79551481673 scopus 로고    scopus 로고
    • The highly homologous T-Box transcription factors, TBX2 and TBX3, have distinct roles in the oncogenic process
    • Peres J, Davis E, Mowla S et al. (2010) The highly homologous T-Box transcription factors, TBX2 and TBX3, have distinct roles in the oncogenic process. Genes Cancer 1:272-82
    • (2010) Genes Cancer , vol.1 , pp. 272-282
    • Peres, J.1    Davis, E.2    Mowla, S.3
  • 31
    • 40849094167 scopus 로고    scopus 로고
    • Human cutaneous melanoma; A review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site
    • Platz A, Egyhazi S, Ringborg U et al. (2008) Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site. Mol Oncol 1:395-405
    • (2008) Mol Oncol , vol.1 , pp. 395-405
    • Platz, A.1    Egyhazi, S.2    Ringborg, U.3
  • 32
    • 0035816677 scopus 로고    scopus 로고
    • Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail
    • Poser I, Dominguez D, de Herreros AG et al. (2001) Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail. J Biol Chem 276:24661-6
    • (2001) J Biol Chem , vol.276 , pp. 24661-24666
    • Poser, I.1    Dominguez, D.2    De Herreros, A.G.3
  • 33
    • 70350554104 scopus 로고    scopus 로고
    • The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer
    • Riesco-Eizaguirre G, Rodriguez I, De la Vieja A et al. (2009) The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer. Cancer Res 69:8317-25
    • (2009) Cancer Res , vol.69 , pp. 8317-8325
    • Riesco-Eizaguirre, G.1    Rodriguez, I.2    De La Vieja, A.3
  • 34
    • 54249133490 scopus 로고    scopus 로고
    • Tbx3 represses E-cadherin expression and enhances melanoma invasiveness
    • Rodriguez M, Aladowicz E, Lanfrancone L et al. (2008) Tbx3 represses E-cadherin expression and enhances melanoma invasiveness. Cancer Res 68:7872-81
    • (2008) Cancer Res , vol.68 , pp. 7872-7881
    • Rodriguez, M.1    Aladowicz, E.2    Lanfrancone, L.3
  • 35
    • 4444363371 scopus 로고    scopus 로고
    • The role of Tbx2 and Tbx3 in mammary development and tumorigenesis
    • Rowley M, Grothey E, Couch FJ (2004) The role of Tbx2 and Tbx3 in mammary development and tumorigenesis. J Mammary Gland Biol Neoplasia 9:109-18
    • (2004) J Mammary Gland Biol Neoplasia , vol.9 , pp. 109-118
    • Rowley, M.1    Grothey, E.2    Couch, F.J.3
  • 36
    • 77952479288 scopus 로고    scopus 로고
    • IGFBP7 is not required for B-RAF-induced melanocyte senescence
    • Scurr LL, Pupo GM, Becker TM et al. (2010) IGFBP7 is not required for B-RAF-induced melanocyte senescence. Cell 141:717-27
    • (2010) Cell , vol.141 , pp. 717-727
    • Scurr, L.L.1    Pupo, G.M.2    Becker, T.M.3
  • 37
    • 46049105728 scopus 로고    scopus 로고
    • Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression
    • Suzuki A, Sekiya S, Buscher D et al. (2008) Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression. Development 135:1589-95
    • (2008) Development , vol.135 , pp. 1589-1595
    • Suzuki, A.1    Sekiya, S.2    Buscher, D.3
  • 38
    • 0037162536 scopus 로고    scopus 로고
    • The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases
    • Tsai CN, Tsai CL, Tse KP et al. (2002) The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci USA 99:10084-9
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10084-10089
    • Tsai, C.N.1    Tsai, C.L.2    Tse, K.P.3
  • 39
    • 16644377744 scopus 로고    scopus 로고
    • Epigenetic silencing of E-and P-cadherin gene expression in human melanoma cell lines
    • Tsutsumida A, Hamada J, Tada M et al. (2004) Epigenetic silencing of E-and P-cadherin gene expression in human melanoma cell lines. Int J Oncol 25:1415-21
    • (2004) Int J Oncol , vol.25 , pp. 1415-1421
    • Tsutsumida, A.1    Hamada, J.2    Tada, M.3
  • 40
    • 36149001019 scopus 로고    scopus 로고
    • Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma
    • Tucci MG, Lucarini G, Brancorsini D et al. (2007) Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma. Br J Dermatol 157:1212-6
    • (2007) Br J Dermatol , vol.157 , pp. 1212-1216
    • Tucci, M.G.1    Lucarini, G.2    Brancorsini, D.3
  • 41
    • 46349084183 scopus 로고    scopus 로고
    • Improving melanoma classification by integrating genetic and morphologic features
    • Viros A, Fridlyand J, Bauer J et al. (2008) Improving melanoma classification by integrating genetic and morphologic features. PLoS Med 5:e120
    • (2008) PLoS Med , vol.5
    • Viros, A.1    Fridlyand, J.2    Bauer, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.