Free glycine accelerates the autoproteolytic activation of human asparaginase

Chemistry and Biology

Volumn 20, Issue 4, 2013, Pages 533-540

  Su, Ying ^a   Karamitros, Christos S ^b   Nomme, Julian ^a   McSorley, Theresa ^b   Konrad, Manfred ^b   Lavie, Arnon ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARAGINASE; ASPARAGINE; GLYCINE; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME STRUCTURE; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING;

ASPARAGINASE; ASPARAGINE; BIOCATALYSIS; CRYSTALLOGRAPHY, X-RAY; GLYCINE; HEK293 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84876489098     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.03.006     Document Type: Article

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