DHL-TauZnNa, a newly synthesized α-lipoic acid derivative, induces autophagy in human colorectal cancer cells

Oncology Reports

Volumn 29, Issue 6, 2013, Pages 2140-2146

  Hiratsuka, Takahiro ^a   Inomata, Masafumi ^a   Kono, Yohei ^a   Yokoyama, Shigeo ^a   Shiraishi, Norio ^a   Kitano, Seigo ^b  

^a OITA UNIVERSITY   (Japan)

^b OITA UNIVERSITY   (Japan)

Author keywords

lipoic acid derivative; Antioxidant; Autophagy; DHL TauZnNa; G2 M arrest

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; DNA; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3 II; SODIUM N (6,8 DIMERCAPTOOCTANOYL) 2 AMINOETHANESULFONATE ZINC; THIOCTIC ACID; TRYPAN BLUE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL VIABILITY; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; DNA FRAGMENTATION; DRUG SYNTHESIS; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CELL CYCLE; CELL SURVIVAL; COLORECTAL NEOPLASMS; COORDINATION COMPLEXES; HT29 CELLS; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; THIOCTIC ACID; TUMOR BURDEN; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84876474765     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2394     Document Type: Article

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