Nuclear receptor CAR specifically activates the two-pore K+ channel kcnk1 gene in male mouse livers, which attenuates phenobarbital-induced hepatic hyperplasia

Toxicological Sciences

Volumn 132, Issue 1, 2013, Pages 151-161

  Saito, Kosuke ^a   Moore, Rick ^a   Negishi, Masahiko ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

CAR; Hepatic hyperplasia; KCNK1; Phenobarbital

Indexed keywords

CELL NUCLEUS RECEPTOR; NUCLEUS RECEPTOR CAR; PHENOBARBITAL; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNK1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; HYPOPHYSIS; LIVER HYPERPLASIA; MALE; MOUSE; NONHUMAN; PROMOTER REGION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; FEMALE; HYPERPLASIA; LIVER; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PHENOBARBITAL; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

MUS;

EID: 84876474460     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs338     Document Type: Article

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