The flame-retardant BDE-99 dose-dependently affects viral replication in CVB3-infected mice

Chemosphere

Volumn 91, Issue 10, 2013, Pages 1434-1438

  Lundgren, Magnus ^a,b   Darnerud, Per Ola ^a   Ilbäck, Nils Gunnar ^a,b  

^a National Food Agency   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Coxsackievirus B3; MCP 1; PBDE; Tissue distribution; Virus levels

Indexed keywords

GENE EXPRESSION; HISTOLOGY; MAMMALS; ORGANIC POLLUTANTS; RISK ASSESSMENT; VIRUSES;

CHEMOATTRACTANTS; COXSACKIEVIRUS B3; MCP-1; PBDE; POLYBROMINATED DIPHENYL ETHER (PBDES); TISSUE DISTRIBUTIONS; VIRAL REPLICATION; VIRUS REPLICATION;

TISSUE;

2,2',4,4',5 PENTA BDE; ANTIVIRUS AGENT; CARBON 14; FLAME RETARDANT; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG;

DOSE-RESPONSE RELATIONSHIP; GENE EXPRESSION; INFECTIOUS DISEASE; MOBILIZATION; PBDE; POLLUTION EXPOSURE; PROTEIN; RISK ASSESSMENT; RODENT; SERUM; VIRAL DISEASE; VIRUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS; COXSACKIE VIRUS INFECTION; COXSACKIEVIRUS B3; FEMALE; GENE EXPRESSION; MOUSE; NONHUMAN; VIRUS REPLICATION;

ANIMALIA; COXSACKIEVIRUS; MUS;

ANIMALS; CARBON RADIOISOTOPES; CHEMOKINE CCL2; COXSACKIEVIRUS INFECTIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROVIRUS B, HUMAN; ENVIRONMENTAL POLLUTANTS; FEMALE; FLAME RETARDANTS; GENE EXPRESSION; HALOGENATED DIPHENYL ETHERS; LIVER; MICE; MICE, INBRED BALB C; REAL-TIME POLYMERASE CHAIN REACTION; VIRUS REPLICATION;

EID: 84876445864     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2013.01.044     Document Type: Article

References (40)

1. Abramsson-Zetterberg L., Wong J., Ilbäck N.G. Acrylamide tissue distribution and genotoxic effects in a common viral infection in mice. Toxicology 2005, 211:70-76.
2. Aitken A.E., Richardson T.A., Morgan E.T. Regulation of drug-metabolizing enzymes and transporters in inflammation. Annu. Rev. Pharmacol. Toxicol. 2006, 46:123-149.
3. Beisel, W.R., 1998. Metabolic response of the host to infections. In: Feigin R.D., Cherry J.D. (Eds.), Textbook of pediatric infectious disease, WB Saunders, Philadelphia, pp. 54-69.
4. Burleson G.R., Lebrec H., Yang Y.G., Ibanes J.D., Pennington K.N., Birnbaum L.S. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on influenza virus host resistance in mice. Fundam. Appl. Toxicol. 1996, 29:40-47.
5. Conti P., DiGioacchino M. MCP-1 and RANTES are mediators of acute and chronic inflammation. Allergy Asthma Proc. 2001, 22:133-137.
6. Cottingham K. Flame retardants have different effects at high and low doses. J. Porteome Res. 2010, 9:1193.
7. Curfs J.H., Meis J.F., Hoogkamp-Korstanje J.A. A primer on cytokines: sources, receptors, effects, and inducers. Clin. Microbiol. Rev. 1997, 10:742-780.
8. Darnerud P.O. Toxic effects of brominated flame retardants in man and in wildlife. Environ. Int. 2003, 29:841-853.
9. Darnerud P.O., Eriksen G.S., Johannesson T., Larsen P.B., Viluksela M. Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology. Environ. Health Perspect. 2001, 109(Suppl. 1):49-68.
10. Darnerud P.O., Wong J., Bergman A., Ilbäck N.G. Common viral infection affects pentabrominated diphenyl ether (PBDE) distribution and metabolic and hormonal activities in mice. Toxicology 2005, 210:159-167.
11. Domingo J.L. Polybrominated diphenyl ethers in food and human dietary exposure: a review of the recent scientific literature. Food Chem. Toxicol. 2012, 50:238-249.
12. Dragomir E., Simionescu M. Monocyte chemoattractant protein-1-a major contributor to the inflammatory process associated with diabetes. Arch. Physiol. Biochem. 2006, 112:239-244.
13. EFSA (European Food Safety Authority) Scientific opinion on polybrominated diphenyl ethers (PBDEs) in food, EFSA panel on contaminants in the food chain (CONTAM). EFSA J. 2011, 9(5):2156.
14. Erratico C.A., Mofatt S.C., Bandiera S.M. Comparative oxidative metabolism of BDE-47 and BDE-99 by rat hepatic microsomes. Toxicol. Sci. 2011, 123:37-47.
15. Frouin H., Lebeuf M., Hammill M., Masson S., Fournier M. Effects of individual polybrominatd diphenyl ether (PBDE congeners on harbour seal immune cells in vitro. Mar. Pollut. Bull. 2010, 60:291-298.
16. Funseth E., Ilbäck N.G. Coxsackievirus B3 infection alters the uptake of 2,3,7,8-tetrachlorodibenzo-p-dioxin into various tissues of the mouse. Toxicology 1994, 90:29-38.
17. Funseth E., Wesslen L., Lindh U., Friman G., Ilbäck N.G. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on trace elements, inflammation and viral clearance in the myocardium during coxsackievirus B3 infection in mice. Sci. Total Environ. 2002, 284:135-147.
18. Guruge K.S., Hikono H., Shimada N., Murakami K., Hasegawa J., Yeung L.W.Y., Yamanaka N., Yamashita N. Effects of perfluorooctane sulfonate (PFOS) on influenza A virus-induced mortality in female B6C3F1 mice. J. Toxicol. Sci. 2009, 34:687-691.
19. Harju M., Hamers T., Kamstra J.H., Sonneveld E., Boon J.P. Quantitative structure-activity relationsship modeling on in vitro endocrine effects and metabolic stability involving 26 selected brominated flame retardants. Environ. Toxicol. Chem. 2007, 26:816-826.
20. Harrad S., de Wit C.A., Abdallah M.A., Bergh C., Björklund J.A., Covaci A., Darnerud P.O., de Boer J., Diamond M., Huber S., Leonards P., Mandelakis M., Östsman C., Haug L.S., Thomsen C., Webster T.F. Indoor contamination with hexabromocyclododecanes, polybrominated diphenyl ethers, and perfluoroalkyl compounds: an important exposure pathway for people?. Environ. Sci. Technol. 2010, 44:3221-3231.
21. Huber S., Ramsingh A.I. Coxsackievirus-induced pancreatitis. Viral Immunol. 2004, 17:358-369.
22. Ilbäck N.G., Fohlman J., Friman G. A common viral infection can change nickel target organ distribution. Toxicol. Appl. Pharmacol. 1992, 114:166-170.
23. Ilbäck N.G., Fohlman J., Friman G., Glynn A.W. Altered distribution of 109 cadmium in mice during viral infection. Toxicology 1992, 71:193-202.
24. Ilbäck N.G., Friman G. Interactions among infections, nutrients and xenobiotics. Crit. Rev. Food Sci. Nutr. 2007, 47:499-519.
25. Isobe T., Oshihoi T., Hamada H., Nakayama K., Yamada T.K., Tajima Y., Amano M., Tanabe S. Contamination status of POPs and BFRs and relationship with parasitic infection in finless porpoises (Neophocaena phocaenoides) from Seto Inland Sea and Omura Bay. Jpn. Mar. Pollut. Bull. 2011, 63:564-571.
26. Lammi N., Karvonen M., Tuomilehto J. Do microbes have a causal role in type 1 diabetes?. Med. Sci. Monit. 2005, 11:RA63-RA69.
27. Lilienthal H., Hack A., Roth-Harer A., Grande S.W., Talsness C.E. Effects of developmental exposure to 2,2,4,4,5-pentabromodiphenyl ether (PBDE-99) on sex steroids, sexual development, and sexually dimorphic behavior in rats. Environ. Health Perspect. 2006, 114:194-201.
28. Lundgren M., Darnerud P.O., Blomberg J., Friman G., Ilbäck N.G. Polybrominated diphenyl ether exposure suppresses cytokines important in the defence to coxsackievirus B3 infection in mice. Toxicol. Lett. 2009, 184:107-113.
29. Lundgren M., Darnerud P.O., Blomberg J., Friman G., Ilbäck N.G. Sequential changes in serum cytokines reflect viral RNA kinetics in target organs of a coxsackievirus B infection in mice. J. Clin. Immunol. 2009, 29:611-619.
30. Lundgren M., Darnerud P.O., Molin Y., Lilienthal H., Blomberg J., Ilbäck N.G. Coxsackievirus B3 infection and PBDE exposure causes organ-specific effects on CYP-gene expression in the mouse. Toxicology 2007, 242:91-99.
31. Lundgren M., Darnerud P.O., Molin Y., Lilienthal H., Blomberg J., Ilbäck N.G. Viral infection and PBDE exposure interact on CYP gene expression and enzyme activities in the mouse liver. Toxicology 2007, 242:100-108.
32. Meerts I.A.T.M., van Zanden J.J., Luijks E.A.C., van Leeuwen-Bol I., Marsh G., Jakobsson E., Bergman å., Brouwer A. Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro. Toxicol. Sci. 2000, 56:95-104.
33. Mohamed N., Elfaitouri A., Fohlman J., Friman G., Blomberg J. A sensitive and quantitative single-tube real-time reverse transcriptase-PCR for detection of enteroviral RNA. J. Clin. Virol. 2004, 30:150-156.
34. Morgan E.T. Regulation of cytochromes P450 during inflammation and infection. Drug Metab. Rev. 1997, 29:1129-1188.
35. Murtaugh M.P., Foss D.L. Inflammatory cytokines and antigen presenting cell activation. Vet. Immunol. Immunopathol. 2002, 87:109-121.
36. Örn U., Eriksson L., Jakobsson E., Bergman å. Synthesis and characterization of polybrominated diphenyl ethers - unlabelled and radiolabelled tetra-, penta- and hexa-bromodiphenyl ethers. Acta Chem. Scand. 1996, 50:802-807.
37. Pacyniak E.P., Cheng X., Cunningham M.L., Crofton K., Klaassen C.D., Guo G.L. The flame retardant, polybrominated diphenyl ethers, are pregnane X receptor activators. Toxicol. Sci. 2007, 97:94-102.
38. Warren T.K., Mitchell K.A., Lawrence B.P. Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppresses the humoral and cell-mediated immune responses to influenza A virus without affecting cytolytic activity in the lung. Toxicol. Sci. 2000, 56:114-123.
39. Watanabe W., Shimizu T., Hino A., Kurokawa M. Effects of decabrominated diphenyl ether (DBDE) on developmental immunotoxicity in offspring mice. Environ. Toxicol. Pharmacol. 2008, 26:315-319.
40. Woodruff J.F. Viral myocarditis. A review. Am. J. Pathol. 1980, 101:425-484.