Dose-response plasma appearance of green tea catechins in adults

Molecular Nutrition and Food Research

Volumn 57, Issue 5, 2013, Pages 833-839

  Renouf, Mathieu ^a   Marmet, Cynthia ^a   Guy, Philippe A ^a   Beaumont, Maurice ^a   Lepage, Mélissa ^a   Williamson, Gary ^b   Dionisi, Fabiola ^a  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Absorption; Bioavailability; Catechins; Dose response; Green tea

Indexed keywords

CATECHIN; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; PLANT EXTRACT;

ADOLESCENT; ADULT; AGED; ARTICLE; BIOAVAILABILITY; BLOOD; CHEMISTRY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; ENTEROHEPATIC CIRCULATION; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MIDDLE AGED; PLANT LEAF; RANDOMIZED CONTROLLED TRIAL; TANDEM MASS SPECTROMETRY; TEA; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BIOLOGICAL AVAILABILITY; CATECHIN; CHROMATOGRAPHY, LIQUID; CROSS-OVER STUDIES; ENTEROHEPATIC CIRCULATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PLANT EXTRACTS; PLANT LEAVES; TANDEM MASS SPECTROMETRY; TEA; YOUNG ADULT;

CAMELLIA SINENSIS;

EID: 84876430969     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200512     Document Type: Article

References (21)

1. Graham, H. N, Green tea composition, consumption and polyphenol chemistry. Prev. Med. 1992, 21, 334-350.
2. Rietveld, A., Wiseman, S, Antioxidant effects of tea: evidence from human clinical trials. J. Nutr. 2003, 133, 3285S-3292S.
3. Cabrera, C., Artacho, R., Gimenez, R., Beneficial effects of green tea-a review, J. Am. College Nutr. 2006, 25, 79-99.
4. Crozier, A., Jaganath, I. B., Clifford, M. N, Dietary phenolics: chemistry, bioavailability and effects on health. Nat. Prod. Rep. 2009, 26, 1001-1043.
5. Wolfram, S, Effects of green tea and EGCg on cardiovascular and metabolic health. J. Am. Coll. Nutr. 2007, 26, 373S-388S.
6. Thielecke, F., Boschmann, M, The potential role of green tea catechins in the prevention of the metabolic syndrome-a review. Phytochemistry 2009, 70, 11-24.
7. Lee, M. J., Wang, Z. Y., Li, H., Chen, L. et al., Analysis of plasma and urinary tea polyphenols in human subjects. Cancer Epidemiol. Biomarkers Prev. 1995, 4, 393-399.
8. Yang, C. S., Chen, L., Lee, M. J., Balentine, B. et al., Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers. Cancer Epidemiol. Biomarkers Prev. 1998, 7, 351-354.
9. Chow, H. H. S., Cai, Y., Alberts, D. S., Hakim, I. et al., Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and Polyphenon E1. Cancer Epidemiol. Biomarkers Prev. 2001, 10, 53-58.
10. Van Amelsvoort, J. M. M., van Het Hof, K. H., Mathot, J. N. J. J., Mulder, T. P. J. et al., Plasma concentration of individual tea catechins after a single oral dose in humans. Xenobiotica 2001, 31, 891-901.
11. Lee, M. J., Maliakal, P., Chen, L., Meng, X. et al., Pharmacokinetics of tea catechins after ingestion of green tea and (-)-Epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability. Cancer Epidemiol. Biomarkers Prev. 2002, 11, 1025-1032.
12. Chow, H. H. S., Cai, Y., Hakim, I. A., Crowell, J. A. et al., Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and Polyphenon E in healthy individuals. Clin. Cancer Res. 2003, 9, 3312-3319.
13. Henning, S. M., Niu, Y., Lee, N. H., Thames, G. D. et al., Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement. Am. J. Clin. Nutr. 2004, 80, 1558-1564.
14. Chow, H. H. S., Hakim, I. A., Vining, D. R., Crowell, J. A. et al., Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals. Clin. Cancer Res. 2005, 11, 4627-4633.
15. Henning, S. M., Niu, Y., Liu, Y., Lee, N. H. et al., Bioavailability and antioxidant effect of epigallocatechin gallate administered in purified form versus as green tea extract in healthy individuals. J. Nutr. Biochem. 2005, 16, 610-616.
16. Stalmach, A., Troufflard, S., Serafini, M., Crozier, A, Absorption, metabolism and excretion of Choladi green tea flavan-3-ols by humans. Mol. Nutr. Food Res. 2009, 53, S44-S53.
17. Del Rio, D., Calani, L., Cordero, C., Salvatore, S. et al., Bioavailability and catabolism of green tea flavan-3-ols in humans. Nutrition 2010, 26, 1110-1116.
18. Kim, S., Lee, M. J., Hong, J., Li, C. et al., Plasma and tissue levels of tea catechins in rats and mice during chronic consumption of green tea polyphenols. Nutr. Cancer 2000, 37, 41-48
19. Renouf, M., Redeuil, K., Longet, K., Marmet, C. et al., Plasma pharmacokinetics of catechin metabolite 4′-O-Me-EGC in healthy humans. Eur. J. Nutr. 2011, 7, 575-80.
20. Renouf, M., Guy, P. A., Marmet, C., Fraering, A. L. et al., Measurement of caffeic and ferulic acid equivalents in plasma after coffee consumption: small intestine and colon are key sites for coffee metabolism. Mol. Nutr. Food. Res. 2010, 54, 760-766.
21. Williamson, G., Dionisi, F., Renouf, M., Flavanols from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages. Mol. Nutr. Food Res. 2011, 55, 1-10.