CADM1 Is a Key Receptor Mediating Human Mast Cell Adhesion to Human Lung Fibroblasts and Airway Smooth Muscle Cells

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Moiseeva, Elena P ^a   Roach, Katy M ^a   Leyland, Mark L ^a   Bradding, Peter ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE 1; CELL PROTEIN; COMPLEMENTARY DNA; NECTIN 3; RECEPTOR PROTEIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP4; UNCLASSIFIED DRUG;

AIRWAY SMOOTH MUSCLE CELL; ARTICLE; ATTENUATION; CELL ADHESION; CELL INTERACTION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LUNG FIBROBLAST; MAST CELL; PRIMARY CELL CULTURE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SMOOTH MUSCLE FIBER;

ADENOVIRIDAE; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; FIBROBLASTS; HUMANS; IMMUNOGLOBULINS; LUNG; MAST CELLS; MYOCYTES, SMOOTH MUSCLE; PROTEIN ISOFORMS; RECEPTORS, CELL SURFACE; REGRESSION ANALYSIS; TRANSDUCTION, GENETIC;

EID: 84876426806     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061579     Document Type: Article

References (41)

1. Moiseeva EP, Bradding P, (2011) Mast cells in lung inflammation. Adv Exp Med Biol 716: 235-269.
2. Heard BE, Dewar A, Corrin B, (1992) Apposition of fibroblasts to mast cells and lymphocytes in normal human lung and in cryptogenic fibrosing alveolitis. Ultrastructure and cell perimeter measurements. J Pathol 166: 303-310.
3. Pesci A, Bertorelli G, Gabrielli M, Olivieri D, (1993) Mast cells in fibrotic lung disorders. Chest 103: 989-996.
4. Bradding P, Roberts JA, Britten KM, Montefort S, Djukanovic R, et al. (1994) Interleukin-4,-5, and-6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 10: 471-480.
5. Carroll NG, Mutavdzic S, James AL, (2002) Increased mast cells and neutrophils in submucosal mucous glands and mucus plugging in patients with asthma. Thorax 57: 677-682.
6. Brightling CE, Bradding P, Symon FA, Holgate ST, Wardlaw AJ, et al. (2002) Mast cell infiltration of airway smooth muscle in asthma. N Engl J Med 346: 1699-1705.
7. Levi-Schaffer F, Austen KF, Caulfield JP, Hein A, Gravallese PM, et al. (1987) Co-culture of human lung-derived mast cells with mouse 3T3 fibroblasts: morphology and IgE-mediated release of histamine, prostaglandin D2, and leukotrienes. J Immunol 139: 494-500.
8. Piliponsky AM, Gleich GJ, Nagler A, Bar I, Levi-Schaffer F, (2003) Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor. Blood 101: 1898-1904.
9. Hollins F, Kaur D, Yang W, Cruse G, Saunders R, et al. (2008) Human Airway Smooth Muscle Promotes Human Lung Mast Cell Survival, Proliferation, and Constitutive Activation: Cooperative Roles for CADM1, Stem Cell Factor, and IL-6. J Immunol 181: 2772-2780.
10. Fitzgerald SM, Lee SA, Hall HK, Chi DS, Krishnaswamy G, (2004) Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact. Am J Respir Cell Mol Biol 30: 585-593.
11. Sellge G, Lorentz A, Gebhardt T, Levi-Schaffer F, Bektas H, et al. (2004) Human intestinal fibroblasts prevent apoptosis in human intestinal mast cells by a mechanism independent of stem cell factor, IL-3, IL-4, and nerve growth factor. J Immunol 172: 260-267.
12. Hirata K, Sugama Y, Ikura Y, Ohsawa M, Inoue Y, et al. (2007) Enhanced mast cell chymase expression in human idiopathic interstitial pneumonia. Int J Mol Med 19: 565-570.
13. Woodman L, Siddiqui S, Cruse G, Sutcliffe A, Saunders R, et al. (2008) Mast Cells Promote Airway Smooth Muscle Cell Differentiation via Autocrine Up-Regulation of TGF-{beta}1. J Immunol 181: 5001-5007.
14. Trautmann A, Krohne G, Brocker EB, Klein CE, (1998) Human mast cells augment fibroblast proliferation by heterotypic cell-cell adhesion and action of IL-4. J Immunol 160: 5053-5057.
15. Gailit J, Marchese MJ, Kew RR, Gruber BL, (2001) The differentiation and function of myofibroblasts is regulated by mast cell mediators. J Invest Dermatol 117: 1113-1119.
16. Levi-Schaffer F, Kupietzky A, (1990) Mast cells enhance migration and proliferation of fibroblasts into an in vitro wound. Exp Cell Res 188: 42-49.
17. Levi-Schaffer F, Rubinchik E, (1995) Activated mast cells are fibrogenic for 3T3 fibroblasts. J Invest Dermatol 104: 999-1003.
18. Garbuzenko E, Nagler A, Pickholtz D, Gillery P, Reich R, et al. (2002) Human mast cells stimulate fibroblast proliferation, collagen synthesis and lattice contraction: a direct role for mast cells in skin fibrosis. Clin Exp Allergy 32: 237-246.
19. Bradding P, Holgate ST, (1999) Immunopathology and human mast cell cytokines. Crit Rev Oncol Haematol 31: 119-133.
20. Yang W, Kaur D, Okayama Y, Ito A, Wardlaw AJ, et al. (2006) Human lung mast cells adhere to human airway smooth muscle, in part, via tumor suppressor in lung cancer-1. J Immunol 176: 1238-1243.
21. Furuno T, Ito A, Koma Y, Watabe K, Yokozaki H, et al. (2005) The SgIGSF/SynCAM mast cell adhesion molecule promotes interaction with nerves. J Immunol 174: 6934-6942.
22. Girodet PO, Ozier A, Trian T, Begueret H, Ousova O, et al. (2010) Mast cell adhesion to bronchial smooth muscle in asthma specifically depends on CD51 and CD44 variant 6. Allergy 65: 1004-1012.
23. Ito A, Jippo T, Wakayama T, Morii E, Koma Yi, et al. (2003) SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF. Blood 101: 2601-2608.
24. Koma Y, Ito A, Watabe K, Hirata T, Mizuki M, et al. (2005) Distinct role for c-kit receptor tyrosine kinase and SgIGSF adhesion molecule in attachment of mast cells to fibroblasts. Lab Invest 85: 426-435.
25. Flicek P, Amode MR, Barrell D, Beal K, Brent S, et al. (2011) Ensembl 2011. Nucleic Acids Res 39: D800-D806.
26. Moiseeva EP, Leyland ML, Bradding P, (2012) CADM1 isoforms differentially regulate human mast cell survival and homotypic adhesion. Cell Mol Life Sci 69: 2751-2764.
27. Moiseeva EP, Leyland ML, Bradding P, (2012) CADM1 is expressed as multiple alternatively spliced functional and dysfunctional isoforms in human mast cells. Mol Immunol 53: 345-354.
28. Masuda M, Yageta M, Fukuhara H, Kuramochi M, Maruyama T, et al. (2002) The tumor suppressor protein TSLC1 is involved in cell-cell adhesion. J Biol Chem 277: 31014-31019.
29. Shingai T, Ikeda W, Kakunaga S, Morimoto K, Takekuni K, et al. (2003) Implications of nectin-like molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion and transmembrane protein localization in epithelial cells. J Biol Chem 278: 35421-35427.
30. Fogel AI, Akins MR, Krupp AJ, Stagi M, Stein V, et al. (2007) SynCAMs organize synapses through heterophilic adhesion. J Neurosci 27: 12516-12530.
31. Galibert L, Diemer GS, Liu Z, Johnson RS, Smith JL, et al. (2005) Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule. J Biol Chem 280: 21955-21964.
32. Wakayama T, Sai Y, Ito A, Kato Y, Kurobo M, et al. (2007) Heterophilic binding of the adhesion molecules poliovirus receptor and immunoglobulin superfamily 4A in the interaction between mouse spermatogenic and Sertoli cells. Biol Reprod 76: 1081-1090.
33. Butterfield JH, Weiler D, Dewald G, Gleich GJ, (1988) Establishment of an immature mast cell line from a patient with mast cell leukemia. Leukaemia Res 12: 345-355.
34. Sanmugalingam D, Wardlaw AJ, Bradding P, (2000) Adhesion of human lung mast cells to bronchial epithelium: evidence for a novel carbohydrate-mediated mechanism. J Leuk Biol 68: 38-46.
35. Brightling CE, Ammit AJ, Kaur D, Black JL, Wardlaw AJ, et al. (2005) The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med 171: 1103-1108.
36. Pechkovsky DV, Hackett TL, An SS, Shaheen F, Murray LA, et al. (2010) Human lung parenchyma but not proximal bronchi produces fibroblasts with enhanced TGF-beta signaling and alpha-SMA expression. Am J Respir Cell Mol Biol 43: 641-651.
37. Sayers EW, Barrett T, Benson DA, Bolton E, Bryant SH, et al. (2011) Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 39: D38-D51.
38. Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K, (2006) Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20: 1123-1136.
39. Kashiwakura J, Yokoi H, Saito H, Okayama Y, (2004) T cell proliferation by direct cross-talk between OX40 ligand on human mast cells and OX40 on human T cells: comparison of gene expression profiles between human tonsillar and lung-cultured mast cells. J Immunol 173: 5247-5257.
40. Fogel AI, Stagi M, Perez de AK, Biederer T, (2011) Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation. EMBO J 30: 4728-4738.
41. Tanabe Y, Kasahara T, Momoi T, Fujita E, (2008) Neuronal RA175/SynCAM1 isoforms are processed by tumor necrosis factor-alpha-converting enzyme (TACE)/ADAM17-like proteases. Neurosci Lett 444: 16-21.