Intentional weight loss in older adults: Useful or wasting disease generating strategy?

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 16, Issue 3, 2013, Pages 284-289

  Darmon, Patrice ^a,b  

^a HÔPITAL SAINTE MARGUERITE   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

obesity; older adults; physical activity; restrictive diet; sarcopenia

Indexed keywords

AEROBIC EXERCISE; BONE DENSITY; CALORIC RESTRICTION; CLINICAL TRIAL; COGNITION; DISEASE EXACERBATION; GERIATRICS; HUMAN; INSULIN RESISTANCE; LEAN BODY WEIGHT; MORTALITY; MUSCLE ATROPHY; OBESITY; RESISTANCE TRAINING; REVIEW; WEIGHT CHANGE; WEIGHT REDUCTION;

AGED; BODY MASS INDEX; BONE DENSITY; CALORIC RESTRICTION; CARDIOVASCULAR DISEASES; CHRONIC DISEASE; COMORBIDITY; EXERCISE; HUMANS; INFLAMMATION; INSULIN RESISTANCE; LIFE EXPECTANCY; MICRONUTRIENTS; OBESITY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS; WASTING SYNDROME; WEIGHT LOSS;

EID: 84876413612     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0b013e32835f503f     Document Type: Review

References (40)

1. United Nations. World population prospects, the 2010 revision: highlights. New York: United Nations; 2011.
2. Flegal MK, Carroll MD, Kit BK, et al. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 2012; 307:491-497.
3. ObEPI 2012. Overweight and obesity in France: 2012 National Survey (in French]. www.roche.fr/portal/roche-fr/obepi-2012- [Accessed 16 October 2012].
4. von Ruesten A, Steffen A, Floegel A, et al. Trend in obesity prevalence in European adult cohort populations during follow-up since 1996 and their predictions to 2015. PLoS One 2011; 6:e27455.
5. Villareal DT, Apovian CM, Kushner RF, et al. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Obes Res 2005; 13:1849-1863.
6. Han TS, Tajar A, Lean ME. Obesity and weight management in the elderly. Br Med Bull 2011; 97:169-196.
7. Mathus-Vliegen EM. Obesity and the elderly. J Clin Gastroenterol 2012; 46:533-544.
8. Mathus-Vliegen EM. On behalf of the Obesity Management Task Force (OMTF) of the European Association for the Study of Obesity (EASO). Prevalence, physiopathology, health consequences and treatment options of obesity in the elderly: a guideline. Obes Facts 2012; 5:460-483.
9. Zamboni M, Mazzali G. Obesity in the elderly: an emerging health issue. Int J Obes 2012; 36:1151-1152.
10. DeCaria JE, Sharp C, Petrella RJ. Scoping review report: obesity in older adults. Int J Obes 2012; 36:1141-1150.
11. Li Z, Heber D. Sarcopenic obesity in the elderly and strategies for weight management. Nutr Rev 2012; 70:57-64.
12. Stenholm S, Harris TB, Rantanen T, et al. Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care 2008; 11:693-700.
13. Chung JY, Kang HT, Lee DC, et al. Body composition and its association with cardiometabolic risk factors in the elderly: a focus on sarcopenic obesity. Arch Gerontol Geriatr 2013; 56:270-278.
14. Bales CW, Buhr G. Is obesity bad for older persons? A systematic review of the pros and cons of weight reduction in later life. J Am Med Dir Assoc 2008; 9:302-312.
15. Witham MD, Avenell A. Interventions to achieve long-term weight loss in obese older people: a systematic review and meta-analysis. Age Ageing 2010; 39:176-184.
16. Rejeski WJ, Marsh AP, Chmelo E, et al. Obesity, intentional weight loss and physical disability in older adults. Obes Rev 2010; 11:671-685.
17. Flicker L, McCaul KA, Hankey GJ, et al. Body mass index and survival in men and women aged 70 to 75. J Am Geriatr Soc 2010; 58:234-241.
18. Oreopoulos A, Kalantar-Zadeh K, Sharma AM, et al. The obesity paradox inthe elderly: potential mechanisms and clinical implications. Clin Geriatr Med 2009; 25:643-659.
19. Dorner TE, Rieder A. Obesity paradox in elderly patients with cardiovascular diseases. Int J Cardiol 2012; 155:56-65.
20. Lee JS, Auyeung TW, Kwok T, et al. Survival benefit of abdominal adiposity: a 6-year follow-up study with dual X-ray absorptiometry in 3978 older adults. Age (Dordr) 2012; 34:597-608.
21. McAuley PA, Kokkinos PF, Oliveira RB, et al. Obesity paradox and cardiorespiratory fitness in 12417 male veterans aged 40 to 70 years. Mayo Clin Proc 2010; 85:115-121.
22. Woo J, Yu R, Yau F. Fitness, fatness and survival in elderly populations. Age (Dordr). 2012 [Epub ahead of print]. doi:10.1007/s11357-012-9398-6.
23. Hong NS, Kim KS, Lee IK, et al. The association between obesity and mortality in the elderly differs by serum concentrations of persistent organic pollutants: a possible explanation for the obesity paradox. Int J Obes 2012; 36:1170-1175.
24. Arnold AM, Newman AB, Cushman M, et al. Body weight dynamics and their association with physical function and mortality in older adults: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci 2010; 65: 63-70.
25. Lee CG, Boyko EJ, Nielson CM, et al. For the Osteoporotic Fractures in Men Study Group. Mortality risk in older men associated with changes in weight, lean mass and fat mass. J Am Geriatr Soc 2011; 59:233-240.
26. Bamia C, Haljkaer J, Lagiou P, et al. Weight change in later life and risk of death amongst the elderly: the European Prospective Investigation into Cancer and Nutrition-Elderly Network on Ageing and Health study. J Intern Med 2010; 268:133-144.
27. Shea MK, Houston DK, Nicklas BJ, et al. The effect of randomization to weight loss on total mortality in older overweight and obese adults: the ADAPT study. J Gerontol A Biol Sci Med Sci 2010; 65:519-525.
28. Shea MK, Nicklas BJ, Houston DK, et al. The effect of intentional weight loss on all-cause mortality in older overweight and obese adults: results of a randomized controlled weight-loss trial. Am J Clin Nutr 2011; 94:839-846.
29. Beavers KM, Lyles MF, Davis CC, et al. Is lost lean mass from intentional weight loss recovered during weight regain in postmenopausal women? Am J Clin Nutr 2011; 94:767-774.
30. Lee JS, Visser M, Tylavsky FA, et al. For the Health ABC Study. Weight loss and regain and effects on body composition: the health, aging, and body composition study. J Gerontol A Biol Sci Med Sci 2010; 65:78-83.
31. Joseph LJ, Prigeon RL, Blumenthal JB, et al. Weight loss and low-intensity exercise for the treatment of metabolic syndrome in obese postmenopausal women. J Gerontol A Biol Sci Med Sci 2011; 66:1022-1029.
32. Imayama I, Ulrich CM, Alfano CM, et al. Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial. Cancer Res 2012; 72:2314-2326.
33. Anton SD, Manini TM, Milsom VA, et al. Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial. Clin Interv Aging 2011; 6:141-149.
34. Rejeski WJ, Ip EH, Bertoni AG, et al. For the Look AHEAD Research Group. Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med 2012; 366:1209-1217.
35. Villareal DT, Chode S, Parimi N, et al. Weight loss, exercise, or both and physical function in obese older adults. N Engl J Med 2011; 364:1218-1229.
36. Shah K, Armamento-Villareal R, Parimi N, et al. Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip bone mineral density induced by weight loss despite decline in bone-active hormones. J Bone Miner Res 2011; 26:2851-2859.
37. Stehr MD, von Lengerke T. Preventing weight gain through exercise and physical activity in the elderly: a systematic review. Maturitas 2012; 72:13-22.
38. Siervo M, Nasti G, Stephan BC, et al. Effects of intentional weight loss on physical and cognitive function in middle-aged and older obese participants: a pilot study. J Am Coll Nutr 2012; 31:79-86.
39. Siervo M, Arnold R, Wells JC, et al. Intentional weight loss in overweight and obese individuals and cognitive function: a systematic review and meta-analysis. Obes Rev 2011; 12:968-983.
40. Driscoll I, Espeland MA, Wassertheil-Smoller S, et al. Women's Health Initiative Study of Cognitive Aging. Weight change and cognitive function: findings from the Women's Health Initiative Study of Cognitive Aging. Obesity 2011; 19:1595-1600.