Enhanced production of CTGF and IL-11 from highly metastatic hepatoma cells under hypoxic conditions: An implication of hepatocellular carcinoma metastasis to bone

Journal of Cancer Research and Clinical Oncology

Volumn 139, Issue 4, 2013, Pages 669-679

  Gao, Ya Bo ^a   Xiang, Zuo Lin ^a   Zhou, Le Yuan ^a   Wu, Zhi Feng ^a   Fan, Jia ^a   Zeng, Hai Ying ^a   Zeng, Zhao Chong ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Bone metastasis; CTGF; Hepatocellular carcinoma; HIF 1 ; IL 11; Osteoprotegerin

Indexed keywords

BIOLOGICAL MARKER; CONNECTIVE TISSUE GROWTH FACTOR; GELATINASE A; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 11; MESSENGER RNA; OSTEOPROTEGERIN;

ADULT; ARTICLE; BONE METASTASIS; CANCER CELL CULTURE; CANCER INCIDENCE; CANCER INVASION; CANCER PROGNOSIS; CELL HYPOXIA; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; FEMALE; HEPATOMA CELL; HUMAN; IN VITRO STUDY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; TUMOR DIFFERENTIATION;

ANOXIA; APOPTOSIS; BLOTTING, WESTERN; BONE NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CONNECTIVE TISSUE GROWTH FACTOR; CULTURE MEDIA, CONDITIONED; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOENZYME TECHNIQUES; INTERLEUKIN-11; LIVER NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84876410961     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-012-1370-4     Document Type: Article

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