Allicin ameliorates cardiac hypertrophy and fibrosis through enhancing of nrf2 antioxidant signaling pathways

Cardiovascular Drugs and Therapy

Volumn 26, Issue 6, 2012, Pages 457-465

  Li, Xian Hui ^a   Li, Chun Yan ^a   Xiang, Zhi Gang ^a   Hu, Jian Jun ^a   Lu, Jiang Ming ^a   Tian, Rong Bo ^a   Jia, Wei ^a  

^a JISHOU UNIVERSITY   (China)

Author keywords

Allicin; Cardiac fibrosis; Cardiac hypertrophy; Nrf2; Oxidative stress

Indexed keywords

ALLICIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FRACTIONAL SHORTENING; GENE EXPRESSION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICULAR END DIASTOLIC DIAMETER; HEART MUSCLE FIBROSIS; HEART PROTECTION; HEART RATE; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HISTOPATHOLOGY; HYPERTENSION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOTIC PUMP; POSTERIOR HEART WALL THICKNESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANGIOTENSIN II; ANIMALS; ANTIOXIDANTS; COLLAGEN; FIBROSIS; GLUTAMATE-CYSTEINE LIGASE; HEMODYNAMICS; HYPERTROPHY, LEFT VENTRICULAR; MALE; NF-E2-RELATED FACTOR 2; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; SULFINIC ACIDS;

EID: 84876406102     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-012-6415-z     Document Type: Article

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