An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes

Journal of Ethnopharmacology

Volumn 130, Issue 2, 2010, Pages 222-230

  Li, Jinqing ^a   Ichikawa, Tomonaga ^a   Jin, Yu ^b   Hofseth, Lorne J ^b   Nagarkatti, Prakash ^a   Nagarkatti, Mitzi ^a   Windust, Anthony ^c   Cui, Taixing ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

American ginseng; Cardiomyocytes; Cell death; Nrf2; Oxidative stress; Panax quinquefolius

Indexed keywords

ADENOVIRUS VECTOR; AMERICAN GINSENG EXTRACT; ANGIOTENSIN II; HYDROGEN PEROXIDE; LUCIFERASE; MESSENGER RNA; PLANT EXTRACT; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIOXIDANT; NFE2L2 PROTEIN, MOUSE; NFE2L2 PROTEIN, RAT; OXIDIZING AGENT;

AMERICAN GINSENG; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL DEATH; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GINSENG; HEART MUSCLE CELL; HEART PROTECTION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; ORAL DRUG ADMINISTRATION; PANAX; PATHOLOGY; RNA INTERFERENCE; TIME;

ADMINISTRATION, ORAL; ANGIOTENSIN II; ANIMALS; ANTIOXIDANTS; CELL DEATH; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; NF-E2-RELATED FACTOR 2; OXIDANTS; OXIDATIVE STRESS; PANAX; PLANT EXTRACTS; RATS; RNA INTERFERENCE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

MURINAE; PANAX GINSENG; PANAX QUINQUEFOLIUS; RATTUS;

EID: 77954958647     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.03.040     Document Type: Article

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