Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo

Journal of Cell Science

Volumn 126, Issue 3, 2013, Pages 778-788

  Efetova, Marina ^a   Petereit, Linda ^a   Rosiewicz, Kamil ^a   Overend, Gayle ^b   Haußig, Florian ^a   Hovemann, Bernhard T ^c   Cabrero, Pablo ^b   Dow, Julian A T ^b   Schwärzel, Martin ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

cAMP signaling pathway; Drosophila malpighian tubules; EPAC; Optogenetics; PAC; Photoactive adenylyl cyclase; PKA; Renal fluid secretion

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CELL TYPE; CENTRAL NERVOUS SYSTEM; DROSOPHILA; HEART; IN VIVO STUDY; KIDNEY EPITHELIUM; KIDNEY FUNCTION; KIDNEY TUBULE; MALPIGHIAN TUBULE; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STELLATE CELL;

ADENYLATE CYCLASE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL COMMUNICATION; CELL LINE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EPITHELIAL CELLS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MALPIGHIAN TUBULES; OPTOGENETICS; ORGAN SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 84876344004     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.114140     Document Type: Article

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