Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells

Reproductive Toxicology

Volumn 38, Issue , 2013, Pages 81-88

  Alves, M G ^a   Neuhaus Oliveira, A ^a   Moreira, P I ^b,c   Socorro, S ^a   Oliveira, P F ^a  

^a UNIVERSITY OF BEIRA INTERIOR   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

2,4 Dichlorophenoxyacetic acid; Glucose metabolism; Sertoli cells; Spermatogenesis

Indexed keywords

2,4 DICHLOROPHENOXYACETIC ACID; 6 PHOSPHOFRUCTOKINASE; CARBOHYDRATE; GLUCOSE; GLUCOSE TRANSPORTER 3; LACTATE DEHYDROGENASE; LACTIC ACID; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOHYDRATE ANALYSIS; DISORDERS OF CARBOHYDRATE METABOLISM; EXPOSURE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; IMMATURITY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; SERTOLI CELL; SPERMATOZOON ABNORMALITY;

2,4-DICHLOROPHENOXYACETIC ACID; ALANINE; ANIMALS; CELLS, CULTURED; ENDOCRINE DISRUPTORS; GLUCOSE; GLUCOSE TRANSPORTER TYPE 3; HERBICIDES; L-LACTATE DEHYDROGENASE; LACTIC ACID; MALE; MONOCARBOXYLIC ACID TRANSPORTERS; MUSCLE PROTEINS; PHOSPHOFRUCTOKINASE-1; RATS; RATS, WISTAR; SERTOLI CELLS;

RATTUS;

EID: 84876339594     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2013.03.005     Document Type: Article

References (53)

1. Bongiovanni B., Ferri A., Brusco A., Rassetto M., Lopez L.M., Evangelista de Duffard A.M., et al. Adverse effects of 2,4-dichlorophenoxyacetic acid on rat cerebellar granule cell cultures were attenuated by amphetamine. Neurotoxicity Research 2011, 19(4):544-555.
2. Kim H.J., Park Y.I., Dong M.S. Effects of 2,4-D and DCP on the DHT-induced androgenic action in human prostate cancer cells. Toxicological Sciences 2005, 88(1):52-59.
3. De Moliner K.L., Evangelista de Duffard A.M., Soto E., Duffard R., Adamo A.M. Induction of apoptosis in cerebellar granule cells by 2,4-dichlorophenoxyacetic acid. Neurochemical Research 2002, 27(11):1439-1446.
4. Brand R.M., Spalding M., Mueller C. Sunscreens can increase dermal penetration of 2,4-dichlorophenoxyacetic acid. Journal of Toxicology - Clinical Toxicology 2002, 40(7):827-832.
5. Duffard R., Garcia G., Rosso S., Bortolozzi A., Madariaga M., di Paolo O., et al. Central nervous system myelin deficit in rats exposed to 2,4-dichlorophenoxyacetic acid throughout lactation. Neurotoxicology and Teratology 1996, 18(6):691-696.
6. Mattsson J.L., Charles J.M., Yano B.L., Cunny H.C., Wilson R.D., Bus J.S. Single-dose and chronic dietary neurotoxicity screening studies on 2,4-dichlorophenoxyacetic acid in rats. Fundamental and Applied Toxicology 1997, 40(1):111-119.
7. Bradberry S.M., Watt B.E., Proudfoot A.T., Vale J.A. Mechanisms of toxicity, clinical features, and management of acute chlorophenoxy herbicide poisoning: a review. Journal of Toxicology - Clinical Toxicology 2000, 38(2):111-122.
8. Palmeira C.M., Moreno A.J., Madeira V.M. Thiols metabolism is altered by the herbicides paraquat, dinoseb and 2,4-D: a study in isolated hepatocytes. Toxicology Letters 1995, 81(2-3):115-123.
9. Maire M.A., Rast C., Landkocz Y., Vasseur P. 2,4-Dichlorophenoxyacetic acid: effects on Syrian hamster embryo (SHE) cell transformation, c-Myc expression, DNA damage and apoptosis. Mutation Research 2007, 631(2):124-136.
10. Troudi A., Soudani N., Mahjoubi Samet A., Ben Amara I., Zeghal N. 2,4-Dichlorophenoxyacetic acid effects on nephrotoxicity in rats during late pregnancy and early postnatal periods. Ecotoxicology and Environment Safety 2011, 74(8):2316-2323.
11. Pochettino A.A., Bongiovanni B., Duffard R.O., Evangelista de Duffard A.M. Oxidative stress in ventral prostate, ovary, and breast by 2,4-dichlorophenoxyacetic acid in pre- and postnatal exposed rats. Environmental Toxicology 2013, 28(1):1-10.
12. Hill R.H., Head S.L., Baker S., Gregg M., Shealy D.B., Bailey S.L., et al. Pesticide residues in urine of adults living in the United States: reference range concentrations. Environmental Research 1995, 71(2):99-108.
13. Griffin R.J., Godfrey V.B., Kim Y.C., Burka L.T. Sex-dependent differences in the disposition of 2,4-dichlorophenoxyacetic acid in Sprague-Dawley rats, B6C3F1 mice, and Syrian hamsters. Drug Metabolism and Disposition 1997, 25(9):1065-1071.
14. Kaye C.I., Rao S., Simpson S.J., Rosenthal F.S., Cohen M.M. Evaluation of chromosomal damage in males exposed to agent orange and their families. Journal of Craniofacial Genetics and Developmental Biology Supplement 1985, 1:259-265.
15. Sturtz N., Evangelista de Duffard A.M., Duffard R. Detection of 2,4-dichlorophenoxyacetic acid (2,4-D) residues in neonates breast-fed by 2,4-D exposed dams. Neurotoxicology 2000, 21(1-2):147-154.
16. Mohammad F.K., St Omer V.E. Behavioral and developmental effects in rats following in utero exposure to 2,4-D/2,4,5-t mixture. Neurobehavioral Toxicology and Teratology 1986, 8(5):551-560.
17. Madrigal-Bujaidar E., Hernandez-Ceruelos A., Chamorro G. Induction of sister chromatid exchanges by 2,4-dichlorophenoxyacetic acid in somatic and germ cells of mice exposed in vivo. Food and Chemical Toxicology 2001, 39(9):941-946.
18. Galimov Sh N., Valeeva G.R. Effect of 2,4-D ecotoxicants on spermatogenesis and fertility of albino rats. Aviakosmicheskaia i Ekologicheskaia Meditsina 1999, 33(1):32-34.
19. Alves M.G., Rato L., Carvalho R.A., Moreira P.I., Socorro S., Oliveira P.F. Hormonal control of Sertoli cells metabolism regulates spermatogenesis. Cellular and Molecular Life Sciences 2013, 70(5):777-793.
20. Rato L., Socorro S., Cavaco J.E., Oliveira P.F. Tubular fluid secretion in the seminiferous epithelium: ion transporters and aquaporins in Sertoli cells. Journal of Membrane Biology 2010, 236(2):215-224.
21. Oliveira P.F., Sousa M., Barros A., Moura T., Rebelo da Costa A. Intracellular pH regulation in human Sertoli cells: role of membrane transporters. Reproduction 2009, 137(2):353-359.
22. Oliveira P.F., Sousa M., Barros A., Moura T., Rebelo da Costa A. Membrane transporters and cytoplasmatic pH regulation on bovine Sertoli cells. Journal of Membrane Biology 2009, 227(1):49-55.
23. Oliveira P.F., Alves M.G., Rato L., Silva J., Sa R., Barros A., et al. Influence of 5alpha-dihydrotestosterone and 17beta-estradiol on human Sertoli cells metabolism. International Journal of Andrology 2011, 34(6 Pt 2):e612-e620.
24. Rato L., Alves M.G., Socorro S., Carvalho R.A., Cavaco J.E., Oliveira P.F. Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells cultured in vitro. Bioscience Reports 2012, 32(1):61-69.
25. Alves M.G., Socorro S., Silva J., Barros A., Sousa M., Cavaco J.E., et al. In vitro cultured human Sertoli cells secrete high amounts of acetate that is stimulated by 17β-estradiol and suppressed by insulin deprivation. Biochimica et Biophysica Acta 2012, 1823(8):1389-1394.
26. Meroni S.B., Riera M.F., Pellizzari E.H., Cigorraga S.B. Regulation of rat Sertoli cell function by FSH: possible role of phosphatidylinositol 3-kinase/protein kinase B pathway. Journal of Endocrinology 2002, 174(2):195-204.
27. Ulisse S., Jannini E.A., Pepe M., De Matteis S., D'Armiento M. Thyroid hormone stimulates glucose transport and GLUT1 mRNA in rat Sertoli cells. Molecular and Cellular Endocrinology 1992, 87(1-3):131-137.
28. Oliveira P.F., Alves M.G., Rato L., Laurentino S., Silva J., Sá R., et al. Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells. Biochimica et Biophysica Acta 2012, 1820(2):84-89.
29. Jutte N.H., Jansen R., Grootegoed J.A., Rommerts F.F., Clausen O.P., van der Molen H.J. Regulation of survival of rat pachytene spermatocytes by lactate supply from Sertoli cells. Journal of Reproduction and Fertility 1982, 65(2):431-438.
30. Rato L., Alves M.G., Socorro S., Duarte A.I., Cavaco J.E., Oliveira P.F. Metabolic regulation is important for spermatogenesis. Nature Reviews Urology 2012, 9(6):330-338.
31. IARC Some halogenated hydrocarbons and pesticide exposures 1986, WHO.
32. Vural N., Burgaz S. A gas chromatographic method for determination of 2,4-D residues in urine after occupational exposure. Bulletin of Environmental Contamination and Toxicology 1984, 33(5):518-524.
33. Rosso S.B., Di Paolo O.A., Evangelista de Duffard A.M., Duffard R. Effects of 2,4-dichlorophenoxyacetic acid on central nervous system of developmental rats. Associated changes in ganglioside pattern. Brain Research 1997, 769(1):163-167.
34. Alexander B.H., Mandel J.S., Baker B.A., Burns C.J., Bartels M.J., Acquavella J.F., et al. Biomonitoring of 2,4-dichlorophenoxyacetic acid exposure and dose in farm families. Environmental Health Perspectives 2007, 115(3):370-376.
35. Thomas K.W., Dosemeci M., Hoppin J.A., Sheldon L.S., Croghan C.W., Gordon S.M., et al. Urinary biomarker, dermal, and air measurement results for 2,4-D and chlorpyrifos farm applicators in the Agricultural Health Study. Journal of Exposure Science and Environmental Epidemiology 2010, 20(2):119-134.
36. Garry V.F., Tarone R.E., Kirsch I.R., Abdallah J.M., Lombardi D.P., Long L.K., et al. Biomarker correlations of urinary 2,4-D levels in foresters: genomic instability and endocrine disruption. Environmental Health Perspectives 2001, 109(5):495-500.
37. Tuschl H., Schwab C. Cytotoxic effects of the herbicide 2,4-dichlorophenoxyacetic acid in HepG2 cells. Food and Chemical Toxicology 2003, 41(3):385-393.
38. Orth J.M. Proliferation of Sertoli cells in fetal and postnatal rats: a quantitative autoradiographic study. Anatomical Record 1982, 203(4):485-492.
39. Li M.W., Mruk D.D., Lee W.M., Cheng C.Y. Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?. International Journal of Biochemistry and Cell Biology 2009, 41(11):2302-2314.
40. Malkov M., Fisher Y., Don J. Developmental schedule of the postnatal rat testis determined by flow cytometry. Biology of Reproduction 1998, 59(1):84-92.
41. Simões V.L., Alves M.G., Martins A.D., Dias T.D., Rato L., Socorro S., et al. Regulation of apoptotic signalling pathways by 5α-dihydrotestosterone and 17β-estradiol in immature rat Sertoli cells. Journal of Steroid Biochemistry and Molecular Biology 2012, 135C:15-23.
42. Vigier M., Weiss M., Perrard M.H., Godet M., Durand P. The effects of FSH and of testosterone on the completion of meiosis and the very early steps of spermiogenesis of the rat: an in vitro study. Journal of Molecular Endocrinology 2004, 33(3):729-742.
43. Monsees T.K., Franz M., Gebhardt S., Winterstein U., Schill W.B., Hayatpour J. Sertoli cells as a target for reproductive hazards. Andrologia 2000, 32(4-5):239-246.
44. Verhoeven G., Cailleau J., Morris I.D. Inhibitory effects of alkane sulphonates on the function of immature rat Leydig, Sertoli and peritubular cells cultured in vitro. Journal of Molecular Endocrinology 1989, 2(2):145-155.
45. Alves M.G., Machado N.G., Sardão V.A., Carvalho R.A., Oliveira P.J. Anti-apoptotic protection afforded by cardioplegic celsior and histidine buffer solutions to hearts subjected to ischemia and ischemia/reperfusion. Journal of Cellular Biochemistry 2011, 112(12):3872-3881.
46. Martineau E., Tea I., Loaec G., Giraudeau P., Akoka S. Strategy for choosing extraction procedures for NMR-based metabolomic analysis of mammalian cells. Analytical and Bioanalytical Chemistry 2011, 401(7):2133-2142.
47. Alves M.G., Oliveira P.F., Martins F.O., Oliveira P.J., Carvalho R.A. Gender-dependent metabolic remodeling during heart preservation in cardioplegic celsior and histidine buffer solution. Journal of Cardiovascular Pharmacology 2012, 59(2):151-157.
48. Alves M.G., Martins A.D., Rato L., Moreira P.I., Socorro S., Oliveira P.F. Molecular mechanisms beyond glucose transport in diabetes-related male infertility. Biochimica et Biophysica Acta 2013, 1832(5):626-635.
49. Mor I., Cheung E.C., Vousden K.H. Control of glycolysis through regulation of PFK1: old friends and recent additions. Cold Spring Harbor Symposia on Quantitative Biology 2011, 76:211-216.
50. Williamson D.H., Lund P., Krebs H.A. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochemical Journal 1967, 103(2):514-527.
51. Hollams E.M., Giles K.M., Thomson A.M., Leedman P.J. MRNA stability and the control of gene expression: implications for human disease. Neurochemical Research 2002, 27(10):957-980.
52. Avvakumov G.V., Cherkasov A., Muller Y.A., Hammond G.L. Structural analyses of sex hormone-binding globulin reveal novel ligands and function. Molecular and Cellular Endocrinology 2010, 316(1):13-23.
53. Hammond G.L. Diverse roles for sex hormone-binding globulin in reproduction. Biology of Reproduction 2011, 85(3):431-441.