Chlorogenic acid exhibits cholesterol lowering and fatty liver attenuating properties by up-regulating the gene expression of PPAR-α in hypercholesterolemic rats induced with a high-cholesterol diet

Phytotherapy Research

Volumn 27, Issue 4, 2013, Pages 545-551

  Wan, Chun Wai ^a   Wong, Candy Ngai Yan ^a   Pin, Wing Kwan ^a   Wong, Marcus Ho Yin ^a   Kwok, Ching Yee ^a   Chan, Robbie Yat Kan ^b   Yu, Peter Hoi Fu ^a,c   Chan, Shun Wan ^a,c  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b BNU HKBU UNITED INTERNATIONAL COLLEGE   (China)

^c State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

Author keywords

chlorogenic acid; cholesterol; hypercholesterolemia; lipid metabolism; liver; peroxisome proliferation activated receptor

Indexed keywords

CHLOROGENIC ACID; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; FATTY LIVER; GENE EXPRESSION; HEART PROTECTION; HYPERCHOLESTEROLEMIA; LIPOPROTEIN BLOOD LEVEL; LIVER PROTECTION; LOW DRUG DOSE; MALE; NONHUMAN; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CHLOROGENIC ACID; CHOLESTEROL, DIETARY; CHOLESTEROL, LDL; DIET; FATTY LIVER; HYPERCHOLESTEROLEMIA; LIPID METABOLISM; LIVER; MALE; PPAR ALPHA; RATS; RATS, SPRAGUE-DAWLEY; UP-REGULATION;

ANIMALIA; RATTUS;

EID: 84876287225     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4751     Document Type: Article

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