메뉴 건너뛰기




Volumn 21, Issue 1, 2013, Pages

Antioxidant capacity of calendula officinalis flowers extract and prevention of radiation induced oropharyngeal mucositis in patients with head and neck cancers: A randomized controlled clinical study

Author keywords

Antioxidant capacity; Calendula officinalis; Gel formulation; OMAS (oral mucositis assessment scale); Radiotherapy induced oral mucositis

Indexed keywords

ANTIOXIDANT; CALENDULA OFFICINALIS EXTRACT; CISPLATIN; FLAVONOID; FLUOROURACIL; MOUTHWASH; PLACEBO; PLANT EXTRACT; POLYPHENOL DERIVATIVE; QUERCETIN; UNCLASSIFIED DRUG;

EID: 84876270713     PISSN: 15608115     EISSN: 20082231     Source Type: Journal    
DOI: 10.1186/2008-2231-21-18     Document Type: Article
Times cited : (91)

References (49)
  • 1
    • 11144356601 scopus 로고    scopus 로고
    • Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis
    • 10.1002/cncr.20163 15108223
    • Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Rubenstein EB, Peterson DE, Schubert M, Keefe D, McGuire D, Epstein J, Elting LS, Cancer 2004 100 2026 2046 10.1002/cncr.20163 15108223
    • (2004) Cancer , vol.100 , pp. 2026-2046
    • Rubenstein, E.B.1    Peterson, D.E.2    Schubert, M.3    Keefe, D.4    McGuire, D.5    Epstein, J.6    Elting, L.S.7
  • 2
    • 5144229908 scopus 로고    scopus 로고
    • A biological approach to mucositis
    • discussion 35-26 15330370
    • A biological approach to mucositis. Sonis ST, J Support Oncol 2004 2 21 32 discussion 35-26 15330370
    • (2004) J Support Oncol , vol.2 , pp. 21-32
    • Sonis, S.T.1
  • 3
    • 0038399940 scopus 로고    scopus 로고
    • Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: A systematic literature review
    • 10.1016/S0167-8140(02)00404-8 12742264
    • Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Trotti A, Bellm LA, Epstein JB, Frame D, Fuchs HJ, Gwede CK, Komaroff E, Radiother Oncol 2003 66 253 262 10.1016/S0167-8140(02) 00404-8 12742264
    • (2003) Radiother Oncol , vol.66 , pp. 253-262
    • Trotti, A.1    Bellm, L.A.2    Epstein, J.B.3    Frame, D.4    Fuchs, H.J.5    Gwede, C.K.6    Komaroff, E.7
  • 4
    • 77952744823 scopus 로고    scopus 로고
    • Oral mucositis
    • 10.1016/j.oraloncology.2010.03.012 20403721
    • Oral mucositis. Raber-Durlacher JE, Elad S, Barasch A, Oral Oncol 2010 46 452 456 10.1016/j.oraloncology.2010.03.012 20403721
    • (2010) Oral Oncol , vol.46 , pp. 452-456
    • Raber-Durlacher, J.E.1    Elad, S.2    Barasch, A.3
  • 5
    • 77956852244 scopus 로고    scopus 로고
    • Attenuation of radiation- and chemoradiation-induced mucositis using gamma-D-glutamyl-L-tryptophan (SCV-07)
    • 10.1111/j.1601-0825.2010.01671.x 20412446
    • Attenuation of radiation- and chemoradiation-induced mucositis using gamma-D-glutamyl-L-tryptophan (SCV-07). Watkins B, Pouliot K, Fey E, Tuthill C, Sonis S, Oral Dis 2010 16 655 660 10.1111/j.1601-0825.2010.01671.x 20412446
    • (2010) Oral Dis , vol.16 , pp. 655-660
    • Watkins, B.1    Pouliot, K.2    Fey, E.3    Tuthill, C.4    Sonis, S.5
  • 6
    • 33749817361 scopus 로고    scopus 로고
    • Treatment of mucositis, including new medications
    • 10.1097/00130404-200609000-00004 17034671
    • Treatment of mucositis, including new medications. Lalla RV, Peterson DE, Cancer J 2006 12 348 354 10.1097/00130404-200609000-00004 17034671
    • (2006) Cancer J , vol.12 , pp. 348-354
    • Lalla, R.V.1    Peterson, D.E.2
  • 7
    • 37249093932 scopus 로고    scopus 로고
    • Management of oral mucositis in patients who have cancer
    • 10.1016/j.cden.2007.10.002 18154865
    • Management of oral mucositis in patients who have cancer. Lalla RV, Sonis ST, Peterson DE, Dent Clin North Am 2008 52 61 77 10.1016/j.cden.2007.10.002 18154865
    • (2008) Dent Clin North Am , vol.52 , pp. 61-77
    • Lalla, R.V.1    Sonis, S.T.2    Peterson, D.E.3
  • 8
    • 40949151478 scopus 로고    scopus 로고
    • The effect of topical application of pure honey on radiation-induced mucositis: A randomized clinical trial
    • 18335118
    • The effect of topical application of pure honey on radiation-induced mucositis: a randomized clinical trial. Motallebnejad M, Akram S, Moghadamnia A, Moulana Z, Omidi S, J Contemp Dent Pract 2008 9 40 47 18335118
    • (2008) J Contemp Dent Pract , vol.9 , pp. 40-47
    • Motallebnejad, M.1    Akram, S.2    Moghadamnia, A.3    Moulana, Z.4    Omidi, S.5
  • 10
    • 0030481770 scopus 로고    scopus 로고
    • Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects
    • 10.1016/S0031-9422(96)00343-3 8987908
    • Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects. Akihisa T, Yasukawa K, Oinuma H, Kasahara Y, Yamanouchi S, Takido M, Kumaki K, Phytochemistry 1996 43 1255 1260 10.1016/S0031-9422(96)00343-3 8987908
    • (1996) Phytochemistry , vol.43 , pp. 1255-1260
    • Akihisa, T.1    Yasukawa, K.2    Oinuma, H.3    Kasahara, Y.4    Yamanouchi, S.5    Takido, M.6    Kumaki, K.7
  • 11
    • 54949104340 scopus 로고    scopus 로고
    • Effect of calendula officinalis flower extract on acute phase proteins, antioxidant defense mechanism and granuloma formation during thermal burns
    • 10.3164/jcbn.2008043 18818737
    • Effect of calendula officinalis flower extract on acute phase proteins, antioxidant defense mechanism and granuloma formation during thermal burns. Chandran PK, Kuttan R, J Clin Biochem Nutr 2008 43 58 64 10.3164/jcbn.2008043 18818737
    • (2008) J Clin Biochem Nutr , vol.43 , pp. 58-64
    • Chandran, P.K.1    Kuttan, R.2
  • 12
    • 2342483078 scopus 로고    scopus 로고
    • Phase III randomized trial of calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer
    • 10.1200/JCO.2004.07.063 15084618
    • Phase III randomized trial of calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. Pommier P, Gomez F, Sunyach MP, D'Hombres A, Carrie C, Montbarbon X, J Clin Oncol 2004 22 1447 1453 10.1200/JCO.2004.07.063 15084618
    • (2004) J Clin Oncol , vol.22 , pp. 1447-1453
    • Pommier, P.1    Gomez, F.2    Sunyach, M.P.3    D'Hombres, A.4    Carrie, C.5    Montbarbon, X.6
  • 13
    • 0023896726 scopus 로고
    • Cytotoxic and antitumoral activity of calendula officinalis extracts
    • 3380875
    • Cytotoxic and antitumoral activity of calendula officinalis extracts. Boucaud-Maitre Y, Algernon O, Raynaud J, Pharmazie 1988 43 220 221 3380875
    • (1988) Pharmazie , vol.43 , pp. 220-221
    • Boucaud-Maitre, Y.1    Algernon, O.2    Raynaud, J.3
  • 14
    • 4444309434 scopus 로고    scopus 로고
    • Hamilton, Ontario: BC Decker Inc 11 23489907
    • Greenberg M, Burket's Oral medicine Hamilton, Ontario: BC Decker Inc 11 2008 178 179 23489907
    • (2008) Burket's Oral Medicine , pp. 178-179
    • Greenberg, M.1
  • 15
    • 0033562462 scopus 로고    scopus 로고
    • Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis Study Group
    • 10.1002/(SICI)1097-0142(19990515)85:10<2103: AID-CNCR2>3.0.CO;2-0 10326686
    • Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis Study Group. Sonis ST, Eilers JP, Epstein JB, LeVeque FG, Liggett WH Jr, Mulagha MT, Peterson DE, Cancer 1999 85 2103 2113 10.1002/(SICI)1097-0142(19990515)85: 10<2103::AID-CNCR2>3.0.CO;2-0 10326686
    • (1999) Cancer , vol.85 , pp. 2103-2113
    • Sonis, S.T.1    Eilers, J.P.2    Epstein, J.B.3    Leveque, F.G.4    Liggett Jr., W.H.5    Mulagha, M.T.6    Peterson, D.E.7
  • 16
    • 0030586361 scopus 로고    scopus 로고
    • The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: The FRAP assay
    • 10.1006/abio.1996.0292 8660627
    • The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Benzie IF, Strain JJ, Anal Biochem 1996 239 70 76 10.1006/abio.1996.0292 8660627
    • (1996) Anal Biochem , vol.239 , pp. 70-76
    • Benzie, I.F.1    Strain, J.J.2
  • 17
    • 33646232499 scopus 로고    scopus 로고
    • In vivo antioxidant activity of procyanidin-rich extracts from grape seed and pine (pinus maritima) bark in rats
    • 10.1024/0300-9831.76.1.22 16711653
    • In vivo antioxidant activity of procyanidin-rich extracts from grape seed and pine (pinus maritima) bark in rats. Busserolles J, Gueux E, Balasinska B, Piriou Y, Rock E, Rayssiguier Y, Mazur A, Int J Vitam Nutr Res 2006 76 22 27 10.1024/0300-9831.76.1.22 16711653
    • (2006) Int J Vitam Nutr Res , vol.76 , pp. 22-27
    • Busserolles, J.1    Gueux, E.2    Balasinska, B.3    Piriou, Y.4    Rock, E.5    Rayssiguier, Y.6    Mazur, A.7
  • 18
    • 0035119007 scopus 로고    scopus 로고
    • Phenolic content and antioxidant activity of olive extracts
    • 10.1016/S0308-8146(00)00288-0
    • Phenolic content and antioxidant activity of olive extracts. McDonald S, Prenzler PD, Antolovich M, Robards K, Food Chemist 2001 73 73 84 10.1016/S0308-8146(00)00288-0
    • (2001) Food Chemist , vol.73 , pp. 73-84
    • McDonald, S.1    Prenzler, P.D.2    Antolovich, M.3    Robards, K.4
  • 19
    • 0036758020 scopus 로고    scopus 로고
    • Estimation of total flavonoid content in propolis by two complementary colorimetric methods
    • Estimation of total flavonoid content in propolis by two complementary colorimetric methods. Chang CC, Yang MH, Wen HM, Chern JC, J Food Drug Analysis 2002 10 178 182
    • (2002) J Food Drug Analysis , vol.10 , pp. 178-182
    • Chang, C.C.1    Yang, M.H.2    Wen, H.M.3    Chern, J.C.4
  • 20
    • 70449525211 scopus 로고    scopus 로고
    • Mucositis: The impact, biology and therapeutic opportunities of oral mucositis
    • 10.1016/j.oraloncology.2009.08.006 19828360
    • Mucositis: the impact, biology and therapeutic opportunities of oral mucositis. Sonis ST, Oral Oncol 2009 45 1015 1020 10.1016/j.oraloncology.2009. 08.006 19828360
    • (2009) Oral Oncol , vol.45 , pp. 1015-1020
    • Sonis, S.T.1
  • 21
    • 77955611551 scopus 로고    scopus 로고
    • Effects of low-level laser therapy on collagen expression and neutrophil infiltrate in 5-fluorouracil-induced oral mucositis in hamsters
    • 10.1002/lsm.20920 20662031
    • Effects of low-level laser therapy on collagen expression and neutrophil infiltrate in 5-fluorouracil-induced oral mucositis in hamsters. Lopes NN, Plapler H, Lalla RV, Chavantes MC, Yoshimura EM, da Silva MA, Alves MT, Lasers Surg Med 2010 42 546 552 10.1002/lsm.20920 20662031
    • (2010) Lasers Surg Med , vol.42 , pp. 546-552
    • Lopes, N.N.1    Plapler, H.2    Lalla, R.V.3    Chavantes, M.C.4    Yoshimura, E.M.5    Da Silva, M.A.6    Alves, M.T.7
  • 22
    • 28244441163 scopus 로고    scopus 로고
    • Analysis of carotenoid composition in petals of calendula (calendula officinalis L)
    • 10.1271/bbb.69.2122 16306694
    • Analysis of carotenoid composition in petals of calendula (calendula officinalis L). Kishimoto S, Maoka T, Sumitomo K, Ohmiya A, Biosci Biotechnol Biochem 2005 69 2122 2128 10.1271/bbb.69.2122 16306694
    • (2005) Biosci Biotechnol Biochem , vol.69 , pp. 2122-2128
    • Kishimoto, S.1    Maoka, T.2    Sumitomo, K.3    Ohmiya, A.4
  • 23
    • 33746336530 scopus 로고    scopus 로고
    • A new extract of the plant calendula officinalis produces a dual in vitro effect: Cytotoxic anti-tumor activity and lymphocyte activation
    • 10.1186/1471-2407-6-119 16677386
    • A new extract of the plant calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation. Jimenez-Medina E, Garcia-Lora A, Paco L, Algarra I, Collado A, Garrido F, BMC Cancer 2006 6 119 10.1186/1471-2407-6-119 16677386
    • (2006) BMC Cancer , vol.6 , pp. 119
    • Jimenez-Medina, E.1    Garcia-Lora, A.2    Paco, L.3    Algarra, I.4    Collado, A.5    Garrido, F.6
  • 24
    • 0037684965 scopus 로고    scopus 로고
    • Preparative purification of the major anti-inflammatory triterpenoid esters from marigold (calendula officinalis)
    • 10.1016/S0367-326X(03)00051-0 12781802
    • Preparative purification of the major anti-inflammatory triterpenoid esters from marigold (calendula officinalis). Hamburger M, Adler S, Baumann D, Forg A, Weinreich B, Fitoterapia 2003 74 328 338 10.1016/S0367-326X(03)00051-0 12781802
    • (2003) Fitoterapia , vol.74 , pp. 328-338
    • Hamburger, M.1    Adler, S.2    Baumann, D.3    Forg, A.4    Weinreich, B.5
  • 25
    • 0037981631 scopus 로고    scopus 로고
    • Naturopathic treatment for ear pain in children
    • 10.1542/peds.111.5.e574 12728112
    • Naturopathic treatment for ear pain in children. Sarrell EM, Cohen HA, Kahan E, Pediatrics 2003 111 574 e579 10.1542/peds.111.5.e574 12728112
    • (2003) Pediatrics , vol.111
    • Sarrell, E.M.1    Cohen, H.A.2    Kahan, E.3
  • 26
    • 0038788959 scopus 로고    scopus 로고
    • Antimicrobial therapy to prevent or treat oral mucositis
    • 10.1016/S1473-3099(03)00668-6 12837345
    • Antimicrobial therapy to prevent or treat oral mucositis. Donnelly JP, Bellm LA, Epstein JB, Sonis ST, Symonds RP, Lancet Infect Dis 2003 3 405 412 10.1016/S1473-3099(03)00668-6 12837345
    • (2003) Lancet Infect Dis , vol.3 , pp. 405-412
    • Donnelly, J.P.1    Bellm, L.A.2    Epstein, J.B.3    Sonis, S.T.4    Symonds, R.P.5
  • 27
    • 0035395343 scopus 로고    scopus 로고
    • Efficacy of Hypericum and calendula oils in the epithelial reconstruction of surgical wounds in childbirth with caesarean section
    • 10.1016/S0014-827X(01)01060-6 11482776
    • Efficacy of Hypericum and calendula oils in the epithelial reconstruction of surgical wounds in childbirth with caesarean section. Lavagna SM, Secci D, Chimenti P, Bonsignore L, Ottaviani A, Bizzarri B, Farmaco 2001 56 451 453 10.1016/S0014-827X(01)01060-6 11482776
    • (2001) Farmaco , vol.56 , pp. 451-453
    • Lavagna, S.M.1    Secci, D.2    Chimenti, P.3    Bonsignore, L.4    Ottaviani, A.5    Bizzarri, B.6
  • 28
    • 0035099168 scopus 로고    scopus 로고
    • Flavonoids as peroxynitrite scavengers: The role of the hydroxyl groups
    • 10.1016/S0887-2333(00)00053-9 11259863
    • Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups. Heijnen CG, Haenen GR, van Acker FA, van der Vijgh WJ, Bast A, Toxicol In Vitro 2001 15 3 6 10.1016/S0887-2333(00)00053-9 11259863
    • (2001) Toxicol in Vitro , vol.15 , pp. 3-6
    • Heijnen, C.G.1    Haenen, G.R.2    Van Acker, F.A.3    Van Der Vijgh, W.J.4    Bast, A.5
  • 29
    • 70349667448 scopus 로고    scopus 로고
    • Clarification of the role of quercetin hydroxyl groups in superoxide generation and cell apoptosis by chemical modification
    • 10.1271/bbb.90253 19734664
    • Clarification of the role of quercetin hydroxyl groups in superoxide generation and cell apoptosis by chemical modification. Sakao K, Fujii M, Hou DX, Biosci Biotechnol Biochem 2009 73 2048 2053 10.1271/bbb.90253 19734664
    • (2009) Biosci Biotechnol Biochem , vol.73 , pp. 2048-2053
    • Sakao, K.1    Fujii, M.2    Hou, D.X.3
  • 30
    • 0019822466 scopus 로고
    • Inhibitory action of some flavonoids on enhanced spontaneous lipid peroxidation following glutathione depletion
    • 10.1055/s-2007-971503 7312988
    • Inhibitory action of some flavonoids on enhanced spontaneous lipid peroxidation following glutathione depletion. Younes M, Siegers CP, Planta Med 1981 43 240 244 10.1055/s-2007-971503 7312988
    • (1981) Planta Med , vol.43 , pp. 240-244
    • Younes, M.1    Siegers, C.P.2
  • 31
    • 0029867672 scopus 로고    scopus 로고
    • Flavonoids - Chemistry, metabolism, cardioprotective effects, and dietary sources
    • 10.1016/0955-2863(95)00168-9
    • Flavonoids-chemistry, metabolism, cardioprotective effects, and dietary sources. Cook NC, Samman S, J Nutri Biochemist 1996 7 66 76 10.1016/0955- 2863(95)00168-9
    • (1996) J Nutri Biochemist , vol.7 , pp. 66-76
    • Cook, N.C.1    Samman, S.2
  • 32
    • 0037246317 scopus 로고    scopus 로고
    • Anti- and pro-oxidant activity of rutin and quercetin derivatives
    • 10.1211/002235702559 12625877
    • Anti- and pro-oxidant activity of rutin and quercetin derivatives. Kessler M, Ubeaud G, Jung L, J Pharm Pharmacol 2003 55 131 142 10.1211/002235702559 12625877
    • (2003) J Pharm Pharmacol , vol.55 , pp. 131-142
    • Kessler, M.1    Ubeaud, G.2    Jung, L.3
  • 33
    • 20944444111 scopus 로고    scopus 로고
    • Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway
    • 10.1159/000085385 15956814
    • Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway. Mandel SA, Avramovich-Tirosh Y, Reznichenko L, Zheng H, Weinreb O, Amit T, Youdim MB, Neurosignals 2005 14 46 60 10.1159/000085385 15956814
    • (2005) Neurosignals , vol.14 , pp. 46-60
    • Mandel, S.A.1    Avramovich-Tirosh, Y.2    Reznichenko, L.3    Zheng, H.4    Weinreb, O.5    Amit, T.6    Youdim, M.B.7
  • 34
    • 70449470908 scopus 로고    scopus 로고
    • Correlations of antioxidant activity against phenolic content revisited: A new approach in data analysis for food and medicinal plants
    • 10.1111/j.1750-3841.2009.01352.x 20492125
    • Correlations of antioxidant activity against phenolic content revisited: a new approach in data analysis for food and medicinal plants. Jacobo-Velazquez DA, Cisneros-Zevallos L, J Food Sci 2009 74 107 R113 10.1111/j.1750-3841.2009. 01352.x 20492125
    • (2009) J Food Sci , vol.74
    • Jacobo-Velazquez, D.A.1    Cisneros-Zevallos, L.2
  • 35
    • 34848919745 scopus 로고    scopus 로고
    • Flavonoids: Hemisynthesis, reactivity, characterization and free radical scavenging activity
    • 10.3390/12092228 17962740
    • Flavonoids: hemisynthesis, reactivity, characterization and free radical scavenging activity. Es-Safi NE, Ghidouche S, Ducrot PH, Molecules 2007 12 2228 2258 10.3390/12092228 17962740
    • (2007) Molecules , vol.12 , pp. 2228-2258
    • Es-Safi, N.E.1    Ghidouche, S.2    Ducrot, P.H.3
  • 36
    • 0032444904 scopus 로고    scopus 로고
    • Free radicals in disease
    • 10.1055/s-2007-1016284 10101806
    • Free radicals in disease. Hogg N, Semin Reprod Endocrinol 1998 16 241 248 10.1055/s-2007-1016284 10101806
    • (1998) Semin Reprod Endocrinol , vol.16 , pp. 241-248
    • Hogg, N.1
  • 37
    • 84869193631 scopus 로고    scopus 로고
    • Inflammation and reactive oxygen species in cardiovascular disease
    • Inflammation and reactive oxygen species in cardiovascular disease. Zhang N, Andresen BT, Zhang C, World J Cardiol 2 408 410
    • World J Cardiol , vol.2 , pp. 408-410
    • Zhang, N.1    Andresen, B.T.2    Zhang, C.3
  • 38
    • 0034190327 scopus 로고    scopus 로고
    • Oxidative stress and cell cycle checkpoint function
    • 10.1016/S0891-5849(00)00224-0 10924858
    • Oxidative stress and cell cycle checkpoint function. Shackelford RE, Kaufmann WK, Paules RS, Free Radic Biol Med 2000 28 1387 1404 10.1016/S0891-5849(00)00224-0 10924858
    • (2000) Free Radic Biol Med , vol.28 , pp. 1387-1404
    • Shackelford, R.E.1    Kaufmann, W.K.2    Paules, R.S.3
  • 39
    • 39149135229 scopus 로고    scopus 로고
    • Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae
    • 10.1016/j.jep.2007.11.025 18164566
    • Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae. Backhouse N, Rosales L, Apablaza C, Goity L, Erazo S, Negrete R, Theodoluz C, J Ethnopharmacol 2008 116 263 269 10.1016/j.jep.2007.11. 025 18164566
    • (2008) J Ethnopharmacol , vol.116 , pp. 263-269
    • Backhouse, N.1    Rosales, L.2    Apablaza, C.3    Goity, L.4    Erazo, S.5    Negrete, R.6    Theodoluz, C.7
  • 40
    • 34548562078 scopus 로고    scopus 로고
    • Anti-inflammatory effects of flavonoids: Genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages
    • 18274639
    • Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Hamalainen M, Nieminen R, Vuorela P, Heinonen M, Moilanen E, Mediators Inflamm 2007 2007 45673 18274639
    • (2007) Mediators Inflamm , vol.2007 , pp. 45673
    • Hamalainen, M.1    Nieminen, R.2    Vuorela, P.3    Heinonen, M.4    Moilanen, E.5
  • 41
    • 38949207932 scopus 로고    scopus 로고
    • Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: Lack of association between antioxidant and lipoxygenase inhibitory activity
    • 10.1016/j.bcp.2007.11.002 18096136
    • Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activity. Loke WM, Proudfoot JM, Stewart S, McKinley AJ, Needs PW, Kroon PA, Hodgson JM, Biochem Pharmacol 2008 75 1045 1053 10.1016/j.bcp.2007.11.002 18096136
    • (2008) Biochem Pharmacol , vol.75 , pp. 1045-1053
    • Loke, W.M.1    Proudfoot, J.M.2    Stewart, S.3    McKinley, A.J.4    Needs, P.W.5    Kroon, P.A.6    Hodgson, J.M.7
  • 42
    • 77956853059 scopus 로고    scopus 로고
    • New thoughts on the initiation of mucositis
    • 10.1111/j.1601-0825.2010.01681.x 20846150
    • New thoughts on the initiation of mucositis. Sonis ST, Oral Dis 2010 16 597 600 10.1111/j.1601-0825.2010.01681.x 20846150
    • (2010) Oral Dis , vol.16 , pp. 597-600
    • Sonis, S.T.1
  • 43
    • 21344461912 scopus 로고    scopus 로고
    • Factors effecting the Th2-like immune response after gamma-irradiation: Low production of IL-12 heterodimer in antigen-presenting cells and small expression of the IL-12 receptor in T cells
    • 10.1080/09553000500077088 16019931
    • Factors effecting the Th2-like immune response after gamma-irradiation: low production of IL-12 heterodimer in antigen-presenting cells and small expression of the IL-12 receptor in T cells. Park HR, Jo SK, Paik SG, Int J Radiat Biol 2005 81 221 231 10.1080/09553000500077088 16019931
    • (2005) Int J Radiat Biol , vol.81 , pp. 221-231
    • Park, H.R.1    Jo, S.K.2    Paik, S.G.3
  • 45
    • 77949621576 scopus 로고    scopus 로고
    • The effect of calendula extract toothpaste on the plaque index and bleeding in gingivitis
    • The effect of calendula extract toothpaste on the plaque index and bleeding in gingivitis. Amoian B, Moghadamnia AA, Mazandarani M, Amoian MM, Mehrmanesh S, J Med Plant 2010 4 132 140
    • (2010) J Med Plant , vol.4 , pp. 132-140
    • Amoian, B.1    Moghadamnia, A.A.2    Mazandarani, M.3    Amoian, M.M.4    Mehrmanesh, S.5
  • 46
    • 0028125141 scopus 로고
    • The role of triterpenoids in the topical anti-inflammatory activity of calendula officinialis [sic] flowers
    • 10.1055/s-2006-959562 7809203
    • The role of triterpenoids in the topical anti-inflammatory activity of calendula officinialis [sic] flowers. Loggia D, Tubaro A, Sosa S, Planta Med 1994 60 516 520 10.1055/s-2006-959562 7809203
    • (1994) Planta Med , vol.60 , pp. 516-520
    • Loggia, D.1    Tubaro, A.2    Sosa, S.3
  • 47
    • 28544453086 scopus 로고    scopus 로고
    • Results of the clinical examination of an ointment with marigold (calendula officinalis) extract in the treatment of venous leg ulcers
    • 16372475
    • Results of the clinical examination of an ointment with marigold (calendula officinalis) extract in the treatment of venous leg ulcers. Duran V, Matic M, Jovanovc M, Mimica N, Gajinov Z, Poljacki M, Boza P, Int J Tissue React 2005 27 101 106 16372475
    • (2005) Int J Tissue React , vol.27 , pp. 101-106
    • Duran, V.1    Matic, M.2    Jovanovc, M.3    Mimica, N.4    Gajinov, Z.5    Poljacki, M.6    Boza, P.7
  • 48
    • 20944436408 scopus 로고    scopus 로고
    • Protective effects of different marigold (calendula officinalis L.) and rosemary cream preparations against sodium-lauryl-sulfate-induced irritant contact dermatitis
    • 10.1159/000085865 15908760
    • Protective effects of different marigold (calendula officinalis L.) and rosemary cream preparations against sodium-lauryl-sulfate-induced irritant contact dermatitis. Fuchs SM, Schliemann-Willers S, Fischer TW, Elsner P, Skin Pharmacol Physiol 2005 18 195 200 10.1159/000085865 15908760
    • (2005) Skin Pharmacol Physiol , vol.18 , pp. 195-200
    • Fuchs, S.M.1    Schliemann-Willers, S.2    Fischer, T.W.3    Elsner, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.