메뉴 건너뛰기




Volumn 94, Issue PART 5, 2013, Pages 1127-1133

Epstein-barr virus LMP2A increases IL-10 production in mitogen-stimulated primary B-cells and B-cell lymphomas

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 10; PHOSPHATIDYLINOSITOL 3 KINASE; VIRUS PROTEIN;

EID: 84876237890     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.049221-0     Document Type: Article
Times cited : (34)

References (43)
  • 2
    • 0033696976 scopus 로고    scopus 로고
    • The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell
    • Babcock, G. J., Hochberg, D. & Thorley-Lawson, A. D. (2000). The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell. Immunity 13, 497-506.
    • (2000) Immunity , vol.13 , pp. 497-506
    • Babcock, G.J.1    Hochberg, D.2    Thorley-Lawson, A.D.3
  • 3
    • 0035229137 scopus 로고    scopus 로고
    • Detection of EBV infection at the single-cell level. Precise quantitation of virus-infected cells in vivo
    • Babcock, G. J., Miyashita-Lin, E. M. & Thorley-Lawson, D. A. (2001). Detection of EBV infection at the single-cell level. Precise quantitation of virus-infected cells in vivo. Methods Mol Biol 174, 103-110.
    • (2001) Methods Mol Biol , vol.174 , pp. 103-110
    • Babcock, G.J.1    Miyashita-Lin, E.M.2    Thorley-Lawson, D.A.3
  • 5
    • 0031135282 scopus 로고    scopus 로고
    • Involvement of IL-10 in the autonomous growth of EBV-transformed B cell lines
    • Beatty, P. R., Krams, S. M. & Martinez, O. M. (1997). Involvement of IL-10 in the autonomous growth of EBV-transformed B cell lines. J Immunol 158, 4045-4051.
    • (1997) J Immunol , vol.158 , pp. 4045-4051
    • Beatty, P.R.1    Krams, S.M.2    Martinez, O.M.3
  • 6
    • 28844444995 scopus 로고    scopus 로고
    • Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomas
    • Bechtel, D., Kurth, J., Unkel, C. & Küppers, R. (2005). Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomas. Blood 106, 4345-4350.
    • (2005) Blood , vol.106 , pp. 4345-4350
    • Bechtel, D.1    Kurth, J.2    Unkel, C.3    Küppers, R.4
  • 7
    • 33749044616 scopus 로고    scopus 로고
    • Analysis of Epstein-Barr virus latent gene expression in endemic Burkitt's lymphoma and nasopharyngeal carcinoma tumour cells by using quantitative real-time PCR assays
    • Bell, A. I., Groves, K., Kelly, G. L., Croom-Carter, D., Hui, E., Chan, A. T. & Rickinson, A. B. (2006). Analysis of Epstein-Barr virus latent gene expression in endemic Burkitt's lymphoma and nasopharyngeal carcinoma tumour cells by using quantitative real-time PCR assays. J Gen Virol 87, 2885-2890.
    • (2006) J Gen Virol , vol.87 , pp. 2885-2890
    • Bell, A.I.1    Groves, K.2    Kelly, G.L.3    Croom-Carter, D.4    Hui, E.5    Chan, A.T.6    Rickinson, A.B.7
  • 8
    • 0035200732 scopus 로고    scopus 로고
    • Signalling events regulating lymphoid growth and survival
    • Brennan, P. (2001). Signalling events regulating lymphoid growth and survival. Semin Cancer Biol 11, 415-421.
    • (2001) Semin Cancer Biol , vol.11 , pp. 415-421
    • Brennan, P.1
  • 9
    • 62649092958 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A accelerates MYC-induced lymphomagenesis
    • Bultema, R., Longnecker, R. & Swanson-Mungerson, M. (2009). Epstein-Barr virus LMP2A accelerates MYC-induced lymphomagenesis. Oncogene 28, 1471-1476.
    • (2009) Oncogene , vol.28 , pp. 1471-1476
    • Bultema, R.1    Longnecker, R.2    Swanson-Mungerson, M.3
  • 10
    • 0028910587 scopus 로고
    • Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes
    • Burdin, N., Van Kooten, C., Galibert, L., Abrams, J. S., Wijdenes, J., Banchereau, J. & Rousset, F. (1995). Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol 154, 2533-2544.
    • (1995) J Immunol , vol.154 , pp. 2533-2544
    • Burdin, N.1    van Kooten, C.2    Galibert, L.3    Abrams, J.S.4    Wijdenes, J.5    Banchereau, J.6    Rousset, F.7
  • 11
    • 0032169313 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals
    • Caldwell, R. G., Wilson, J. B., Anderson, S. J. & Longnecker, R. (1998). Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity 9, 405-411.
    • (1998) Immunity , vol.9 , pp. 405-411
    • Caldwell, R.G.1    Wilson, J.B.2    Anderson, S.J.3    Longnecker, R.4
  • 12
    • 0030866267 scopus 로고    scopus 로고
    • Interleukin-10 in non-Hodgkin's lymphoma
    • Cortes, J. & Kurzrock, R. (1997). Interleukin-10 in non-Hodgkin's lymphoma. Leuk Lymphoma 26, 251-259.
    • (1997) Leuk Lymphoma , vol.26 , pp. 251-259
    • Cortes, J.1    Kurzrock, R.2
  • 13
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G. & de Vries, J. E. (1991). Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174, 1209-1220.
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • de Waal, M.R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 14
    • 0029947349 scopus 로고    scopus 로고
    • Detection of the latent form of Epstein-Barr virus DNA in the peripheral blood of healthy individuals
    • Decker, L. L., Klaman, L. D. & Thorley-Lawson, D. A. (1996). Detection of the latent form of Epstein-Barr virus DNA in the peripheral blood of healthy individuals. J Virol 70, 3286-3289.
    • (1996) J Virol , vol.70 , pp. 3286-3289
    • Decker, L.L.1    Klaman, L.D.2    Thorley-Lawson, D.A.3
  • 15
    • 0026721289 scopus 로고
    • Identification and induction of keratinocyte-derived IL-10
    • Enk, A. H. & Katz, S. I. (1992). Identification and induction of keratinocyte-derived IL-10. J Immunol 149, 92-95.
    • (1992) J Immunol , vol.149 , pp. 92-95
    • Enk, A.H.1    Katz, S.I.2
  • 16
    • 0842326032 scopus 로고    scopus 로고
    • Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway
    • Fukuda, M. & Longnecker, R. (2004). Latent membrane protein 2A inhibits transforming growth factor-beta 1-induced apoptosis through the phosphatidylinositol 3-kinase/Akt pathway. J Virol 78, 1697-1705.
    • (2004) J Virol , vol.78 , pp. 1697-1705
    • Fukuda, M.1    Longnecker, R.2
  • 17
    • 80054805087 scopus 로고    scopus 로고
    • Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+(EBV+) B cell lymphomas
    • Hatton, O., Phillips, L. K., Vaysberg, M., Hurwich, J., Krams, S. M. & Martinez, O. M. (2011). Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+(EBV+) B cell lymphomas. J Biol Chem 286, 37368-37378.
    • (2011) J Biol Chem , vol.286 , pp. 37368-37378
    • Hatton, O.1    Phillips, L.K.2    Vaysberg, M.3    Hurwich, J.4    Krams, S.M.5    Martinez, O.M.6
  • 19
    • 33947599292 scopus 로고    scopus 로고
    • Cholesterol is critical for Epstein-Barr virus latent membrane protein 2A trafficking and protein stability
    • Ikeda, M. & Longnecker, R. (2007). Cholesterol is critical for Epstein-Barr virus latent membrane protein 2A trafficking and protein stability. Virology 360, 461-468.
    • (2007) Virology , vol.360 , pp. 461-468
    • Ikeda, M.1    Longnecker, R.2
  • 20
    • 2142750277 scopus 로고    scopus 로고
    • Latent membrane protein 2A, a viral B cell receptor homologue, induces CD5+ B-1 cell development
    • Ikeda, A., Merchant, M., Lev, L., Longnecker, R. & Ikeda, M. (2004). Latent membrane protein 2A, a viral B cell receptor homologue, induces CD5+ B-1 cell development. J Immunol 172, 5329-5337.
    • (2004) J Immunol , vol.172 , pp. 5329-5337
    • Ikeda, A.1    Merchant, M.2    Lev, L.3    Longnecker, R.4    Ikeda, M.5
  • 21
    • 84863653228 scopus 로고    scopus 로고
    • The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination
    • Jochum, S., Moosmann, A., Lang, S., Hammerschmidt, W. & Zeidler, R. (2012). The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination. PLoS Pathog 8, e1002704.
    • (2012) PLoS Pathog , vol.8
    • Jochum, S.1    Moosmann, A.2    Lang, S.3    Hammerschmidt, W.4    Zeidler, R.5
  • 22
    • 0031828850 scopus 로고    scopus 로고
    • A review of the association between interleukin-10 and human B-cell malignancies
    • Khatri, V. P. & Caligiuri, M. A. (1998). A review of the association between interleukin-10 and human B-cell malignancies. Cancer Immunol Immunother 46, 239-244.
    • (1998) Cancer Immunol Immunother , vol.46 , pp. 239-244
    • Khatri, V.P.1    Caligiuri, M.A.2
  • 23
    • 69249221314 scopus 로고    scopus 로고
    • Interleukin-21 regulates expression of the immediate-early lytic cycle genes and proteins in Epstein-Barr virus infected B cells
    • Konforte, D. & Paige, C. J. (2009). Interleukin-21 regulates expression of the immediate-early lytic cycle genes and proteins in Epstein-Barr virus infected B cells. Virus Res 144, 339-343.
    • (2009) Virus Res , vol.144 , pp. 339-343
    • Konforte, D.1    Paige, C.J.2
  • 24
    • 40049106893 scopus 로고    scopus 로고
    • Latent membrane protein 1 of EBV activates phosphatidylinositol 3-kinase to induce production of IL-10
    • Lambert, S. L. & Martinez, O. M. (2007). Latent membrane protein 1 of EBV activates phosphatidylinositol 3-kinase to induce production of IL-10. J Immunol 179, 8225-8234.
    • (2007) J Immunol , vol.179 , pp. 8225-8234
    • Lambert, S.L.1    Martinez, O.M.2
  • 25
    • 0031567973 scopus 로고    scopus 로고
    • The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor
    • Liu, Y., de Waal Malefyt, R., Briere, F., Parham, C., Bridon, J. M., Banchereau, J., Moore, K. W. & Xu, J. (1997). The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor. J Immunol 158, 604-613.
    • (1997) J Immunol , vol.158 , pp. 604-613
    • Liu, Y.1    de Waal, M.R.2    Briere, F.3    Parham, C.4    Bridon, J.M.5    Banchereau, J.6    Moore, K.W.7    Xu, J.8
  • 26
    • 0026739517 scopus 로고
    • The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential
    • Longnecker, R., Miller, C. L., Miao, X. Q., Marchini, A. & Kieff, E. (1992). The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential. J Virol 66, 6461-6469.
    • (1992) J Virol , vol.66 , pp. 6461-6469
    • Longnecker, R.1    Miller, C.L.2    Miao, X.Q.3    Marchini, A.4    Kieff, E.5
  • 27
    • 34948821852 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for Bcell survival
    • Mancao, C. & Hammerschmidt, W. (2007). Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for Bcell survival. Blood 110, 3715-3721.
    • (2007) Blood , vol.110 , pp. 3715-3721
    • Mancao, C.1    Hammerschmidt, W.2
  • 28
    • 0027211796 scopus 로고
    • Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes
    • Miller, C. L., Longnecker, R. & Kieff, E. (1993). Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes. J Virol 67, 3087-3094.
    • (1993) J Virol , vol.67 , pp. 3087-3094
    • Miller, C.L.1    Longnecker, R.2    Kieff, E.3
  • 29
    • 30744458329 scopus 로고    scopus 로고
    • A case for regulatory B cells
    • Mizoguchi, A. & Bhan, A. K. (2006). A case for regulatory B cells. J Immunol 176, 705-710.
    • (2006) J Immunol , vol.176 , pp. 705-710
    • Mizoguchi, A.1    Bhan, A.K.2
  • 30
    • 0030791517 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) infection in infectious mononucleosis: Virus latency, replication and phenotype of EBV-infected cells
    • Niedobitek, G., Agathanggelou, A., Herbst, H., Whitehead, L., Wright, D. H. & Young, L. S. (1997). Epstein-Barr virus (EBV) infection in infectious mononucleosis: virus latency, replication and phenotype of EBV-infected cells. J Pathol 182, 151-159.
    • (1997) J Pathol , vol.182 , pp. 151-159
    • Niedobitek, G.1    Agathanggelou, A.2    Herbst, H.3    Whitehead, L.4    Wright, D.H.5    Young, L.S.6
  • 31
    • 0026445046 scopus 로고
    • Cytokines and Ly-1 (B1) B cells
    • O'Garra, A. & Howard, M. (1992). Cytokines and Ly-1 (B1) B cells. Int Rev Immunol 8, 219-234.
    • (1992) Int Rev Immunol , vol.8 , pp. 219-234
    • O'Garra, A.1    Howard, M.2
  • 32
    • 34249678457 scopus 로고    scopus 로고
    • T(H)1 cells control themselves by producing interleukin-10
    • O'Garra, A. & Vieira, P. (2007). T(H)1 cells control themselves by producing interleukin-10. Nat Rev Immunol 7, 425-428.
    • (2007) Nat Rev Immunol , vol.7 , pp. 425-428
    • O'Garra, A.1    Vieira, P.2
  • 33
    • 0025111466 scopus 로고
    • Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10
    • Authors other
    • O'Garra, A., Stapleton, G., Dhar, V., Pearce, M., Schumacher, J., Rugo, H., Barbis, D., Stall, A., Cupp, J. & other authors (1990). Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10. Int Immunol 2, 821-832.
    • (1990) Int Immunol , vol.2 , pp. 821-832
    • O'Garra, A.1    Stapleton, G.2    Dhar, V.3    Pearce, M.4    Schumacher, J.5    Rugo, H.6    Barbis, D.7    Stall, A.8    Cupp, J.9
  • 34
    • 9644279753 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway
    • Portis, T. & Longnecker, R. (2004). Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway. Oncogene 23, 8619-8628.
    • (2004) Oncogene , vol.23 , pp. 8619-8628
    • Portis, T.1    Longnecker, R.2
  • 35
    • 0030933992 scopus 로고    scopus 로고
    • In vivo growth of Epstein-Barr virus transformed B cells with mutations in latent membrane protein 2 (LMP2)
    • Rochford, R., Miller, C. L., Cannon, M. J., Izumi, K. M., Kieff, E. & Longnecker, R. (1997). In vivo growth of Epstein-Barr virus transformed B cells with mutations in latent membrane protein 2 (LMP2). Arch Virol 142, 707-720.
    • (1997) Arch Virol , vol.142 , pp. 707-720
    • Rochford, R.1    Miller, C.L.2    Cannon, M.J.3    Izumi, K.M.4    Kieff, E.5    Longnecker, R.6
  • 36
    • 0028081189 scopus 로고
    • Molecular characterization and determination of the coding capacity of the genome of equine herpesvirus type 2 between the genome coordinates 0.235 and 0.258 (the EcoRI DNA fragment N; 4.2 kbp)
    • Rode, H. J., Bugert, J. J., Handermann, M., Schnitzler, P., Kehm, R., Janssen, W., Delius, H. & Darai, G. (1994). Molecular characterization and determination of the coding capacity of the genome of equine herpesvirus type 2 between the genome coordinates 0.235 and 0.258 (the EcoRI DNA fragment N; 4.2 kbp). Virus Genes 9, 61-75.
    • (1994) Virus Genes , vol.9 , pp. 61-75
    • Rode, H.J.1    Bugert, J.J.2    Handermann, M.3    Schnitzler, P.4    Kehm, R.5    Janssen, W.6    Delius, H.7    Darai, G.8
  • 37
    • 47049129929 scopus 로고    scopus 로고
    • Epstein-Barr virusencoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling
    • Samanta, M., Iwakiri, D. & Takada, K. (2008). Epstein-Barr virusencoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling. Oncogene 27, 4150-4160.
    • (2008) Oncogene , vol.27 , pp. 4150-4160
    • Samanta, M.1    Iwakiri, D.2    Takada, K.3
  • 38
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva, M. & O'Garra, A. (2010). The regulation of IL-10 production by immune cells. Nat Rev Immunol 10, 170-181.
    • (2010) Nat Rev Immunol , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 39
    • 33745781482 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A enhances B-cell responses in vivo and in vitro
    • Swanson-Mungerson, M., Bultema, R. & Longnecker, R. (2006). Epstein-Barr virus LMP2A enhances B-cell responses in vivo and in vitro. J Virol 80, 6764-6770.
    • (2006) J Virol , vol.80 , pp. 6764-6770
    • Swanson-Mungerson, M.1    Bultema, R.2    Longnecker, R.3
  • 40
    • 77956291319 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A imposes sensitivity to apoptosis
    • Swanson-Mungerson, M., Bultema, R. & Longnecker, R. (2010). Epstein-Barr virus LMP2A imposes sensitivity to apoptosis. J Gen Virol 91, 2197-2202.
    • (2010) J Gen Virol , vol.91 , pp. 2197-2202
    • Swanson-Mungerson, M.1    Bultema, R.2    Longnecker, R.3
  • 41
    • 67651015678 scopus 로고    scopus 로고
    • EBV Zta protein induces the expression of interleukin-13, promoting the proliferation of EBVinfected B cells and lymphoblastoid cell lines
    • Tsai, S. C., Lin, S. J., Chen, P. W., Luo, W. Y., Yeh, T. H., Wang, H. W., Chen, C. J. & Tsai, C. H. (2009). EBV Zta protein induces the expression of interleukin-13, promoting the proliferation of EBVinfected B cells and lymphoblastoid cell lines. Blood 114, 109-118.
    • (2009) Blood , vol.114 , pp. 109-118
    • Tsai, S.C.1    Lin, S.J.2    Chen, P.W.3    Luo, W.Y.4    Yeh, T.H.5    Wang, H.W.6    Chen, C.J.7    Tsai, C.H.8
  • 42
    • 0035866322 scopus 로고    scopus 로고
    • The Epstein-Barr virus latent membrane protein 1 induces interleukin- 10 in Burkitt's lymphoma cells but not in Hodgkin's cells involving the p38/SAPK2 pathway
    • Vockerodt, M., Haier, B., Buttgereit, P., Tesch, H. & Kube, D. (2001). The Epstein-Barr virus latent membrane protein 1 induces interleukin- 10 in Burkitt's lymphoma cells but not in Hodgkin's cells involving the p38/SAPK2 pathway. Virology 280, 183-198.
    • (2001) Virology , vol.280 , pp. 183-198
    • Vockerodt, M.1    Haier, B.2    Buttgereit, P.3    Tesch, H.4    Kube, D.5
  • 43
    • 84864554412 scopus 로고    scopus 로고
    • Epstein-Barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties
    • Yoon, S. I., Jones, B. C., Logsdon, N. J., Harris, B. D., Kuruganti, S. & Walter, M. R. (2012). Epstein-Barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties. J Biol Chem 287, 26586-26595.
    • (2012) J Biol Chem , vol.287 , pp. 26586-26595
    • Yoon, S.I.1    Jones, B.C.2    Logsdon, N.J.3    Harris, B.D.4    Kuruganti, S.5    Walter, M.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.