Postoperative analgesia in elderly patients

Drugs and Aging

Volumn 30, Issue 2, 2013, Pages 81-90

  Falzone, Elisabeth ^a   Hoffmann, Clément ^a   Keita, Hawa ^b  

^a PERCY MILITARY HOSPITAL   (France)

^b HÔPITAL LOUIS MOURIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALFENTANIL; BUPIVACAINE; CODEINE; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; DROPERIDOL; FENTANYL; IBUPROFEN; KETAMINE; KETOPROFEN; KETOROLAC; LOCAL ANESTHETIC AGENT; MONOAMINE OXIDASE INHIBITOR; MORPHINE; NAPROXEN; NEFOPAM; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PARACETAMOL; REMIFENTANIL; ROPIVACAINE; SEROTONIN UPTAKE INHIBITOR; SUFENTANIL; TRAMADOL; WARFARIN;

ADVERSE OUTCOME; AGE; AGING; ALGOPLUS SCALE; ANALGESIA; ARTICLE; ASTHENIA; CARDIOVASCULAR DISEASE; CLOSED ANGLE GLAUCOMA; COGNITIVE DEFECT; COMORBIDITY; CONFUSION; CONSTIPATION; CONTINUOUS INFUSION; DEMENTIA; DIGESTIVE SYSTEM PERFORATION; DIZZINESS; DOLOPLUS 2 SCALE; DROWSINESS; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG OVERDOSE; EPIDURAL ANESTHESIA; FACIAL PAIN SCALE; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL SYMPTOM; HEART FUNCTION; HIGH RISK PATIENT; HUMAN; HYPOTENSION; INJECTION SITE PAIN; KIDNEY DISEASE; KIDNEY FAILURE; KIDNEY FUNCTION; LIVER FUNCTION; LIVER NECROSIS; LOCAL ANESTHESIA; LOW DRUG DOSE; MOTOR BLOCK; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NAUSEA; NAUSEA AND VOMITING; NEPHROTOXICITY; NUMERIC RATING SCALE; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE ANALGESIA; POSTOPERATIVE DELIRIUM; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PRURITUS; RECOMMENDED DRUG DOSE; RESPIRATION DEPRESSION; SEDATION; SEROTONIN SYNDROME; SIDE EFFECT; STOMACH DISEASE; SWEATING; TACHYCARDIA; TREATMENT CONTRAINDICATION; URINE RETENTION; VERBAL RATING SCALE; VISUAL ANALOG SCALE; VOMITING;

AGED; AGING; ANALGESIA; ANALGESICS; HUMANS; PAIN MEASUREMENT; PAIN, POSTOPERATIVE;

EID: 84876229676     PISSN: 1170229X     EISSN: 11791969     Source Type: Journal    
DOI: 10.1007/s40266-012-0047-7     Document Type: Article

References (70)

1. Aubrun F, Marmion F. The elderly patient and postoperative pain treatment. Best Pract Res Clin Anaesthesiol. 2007;21(1):109-27.
2. Saleh KL. The elderly patient in the post anesthesia care unit. Nurs Clin N Am. 1993;28(3):507-18.
3. Macintyre PE, Upton RN, Ludbrook GL. Acute pain management in the elderly patient. In: Rowbotham DJ, Macintyre PE, editors. Acute pain: clinical management. London: Arnold; 2003. p. 117-36.
4. Jin F, Chung F. Minimizing perioperative adverse events in the elderly. Br J Anaesth. 2001;87(4):608-24.
5. Gagliese L. Assessment of pain in elderly people. In: Turk DC, Melzack R, editors. Handbook of pain assessment. New York: The Guilford Press; 2001. p. 119-33.
6. Herr KA, Garand L. Assessment and measurement of pain in older adults. Clin Geriatr Med. 2001;17(3):457-78. (vi).
7. Coldrey JC, Upton RN, Macintyre PE. Advances in analgesia in the older patient. Best Pract Res Clin Anaesthesiol. 2011;25(3):367-78.
8. Gagliese L. Pain and aging: the emergence of a new subfield of pain research. J Pain. 2009;10(4):343-53.
9. Gagliese L, Katz J. Age differences in postoperative pain are scale dependent: a comparison of measures of pain intensity and quality in younger and older surgical patients. Pain. 2003;103(1-2):11-20.
10. Gagliese L, Weizblit N, Ellis W, et al. The measurement of postoperative pain: a comparison of intensity scales in younger and older surgical patients. Pain. 2005;117(3):412-20.
11. Herr KA, Mobily PR, Kohout FJ, et al. Evaluation of the faces pain scale for use with the elderly. Clin J Pain. 1998;14(1):29-38.
12. Zwakhalen SM, Hamers JP, Abu-Saad HH, et al. Pain in elderly people with severe dementia: a systematic review of behavioural pain assessment tools. BMC Geriatr. 2006;6:3.
13. Torvik K, Kaasa S, Kirkevold O, et al. Validation of Doloplus-2 among nonverbal nursing home patients: an evaluation of Doloplus-2 in a clinical setting. BMC Geriatr. 2010;10:9.
14. Rat P, Jouve E, Pickering G, et al. Validation of an acute pain-behavior scale for older persons with inability to communicate verbally: Algoplus. Eur J Pain. 2010;15(2):198 e1-e10.
15. Ravaud P, Keita H, Porcher R, et al. Randomized clinical trial to assess the effect of an educational programme designed to improve nurses' assessment and recording of postoperative pain. Br J Surg. 2004;91(6):692-8.
16. Liukas A, Kuusniemi K, Aantaa R, et al. Pharmacokinetics of intravenous paracetamol in elderly patients. Clin Pharmacokinet. 2011;50(2):121-9.
17. Barkin RL, Beckerman M, Blum SL, et al. Should nonsteroidal anti-inflammatory drugs (NSAIDs) be prescribed to the older adult? Drugs Aging. 2010;27(10):775-89.
18. Macintyre PE, Schug SA, Scott DA, Visser EJ, Walker SM, APM: SE Working Group of the Australian and New Zealand College of Anaesthetists and Faculty of Pain Medicine. Acute pain management: scientific evidence. 3rd ed. Melbourne: ANZCA & FPM; 2010.
19. Kapfer B, Alfonsi P, Guignard B, et al. Nefopam and ketamine comparably enhance postoperative analgesia. Anesth Analg. 2005;100(1):169-74.
20. Mimoz O, Incagnoli P, Josse C, et al. Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. Anaesthesia. 2001;56(6):520-5.
21. Guirimand F, Dupont X, Bouhassira D, et al. Nefopam strongly depresses the nociceptive flexion (R(III)) reflex in humans. Pain. 1999;80(1-2):399-404.
22. Heel RC, Brogden RN, Pakes GE, et al. Nefopam: a review of its pharmacological properties and therapeutic efficacy. Drugs. 1980;19(4):249-67.
23. Bhatt AM, Pleuvry BJ, Maddison SE. Respiratory and metabolic effects of oral nefopam in human volunteers. Br J Clin Pharmacol. 1981;11(2):209-11.
24. Gloth FM 3rd. Pain management in older adults: prevention and treatment. J Am Geriatr Soc. 2001;49(2):188-99.
25. Brouquet A, Cudennec T, Benoist S, et al. Impaired mobility, ASA status and administration of tramadol are risk factors for postoperative delirium in patients aged 75 years or more after major abdominal surgery. Ann Surg. 2010;251(4):759-65.
26. Jick H, Derby LE, Vasilakis C, et al. The risk of seizures associated with tramadol. Pharmacotherapy. 1998;18(3):607-11.
27. Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med. 2005;352(11):1112-20.
28. Gillman PK. A review of serotonin toxicity data: implications for the mechanisms of antidepressant drug action. Biol Psychiatry. 2006;59(11):1046-51.
29. Chauvin C, Sandouk P, Scherrmann JM, et al. Morphine pharmacokinetics in renal failure. Anesthesiology. 1987;66:327-31.
30. Pergolizzi J, Boger RH, Budd K, et al. Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone). Pain Pract. 2008;8(4):287-313.
31. Aubrun F, Bunge D, Langeron O, et al. Postoperative morphine consumption in the elderly patient. Anesthesiology. 2003;99(1):160-5.
32. Burns JW, Hodsman NBA, McLintock TTC, et al. The influence of patient characteristics on the requirements for postoperative analgesia. Anaesthesia. 1989;44:2-6.
33. Macintyre PE, Jarvis DA. Age is the best predictor of postoperative morphine requirements. Pain. 1996;64(2):357-64.
34. Ready LB. Acute pain: lessons learned from 25,000 patients. Reg Anesth Pain Med. 1999;24(6):499-505.
35. Kehlet H. Surgical stress: the role of pain and analgesia. Br J Anaesth. 1989;63(2):189-95.
36. Kehlet H, Werner M, Perkins F. Balanced analgesia: what is it and what are its advantages in postoperative pain? Drug. 1999;58:793-7.
37. Elia N, Lysakowski C, Tramer MR. Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials. Anesthesiology. 2005;103(6):1296-304.
38. Evans MS, Lysakowski C, Tramer MR. Nefopam for the prevention of postoperative pain: quantitative systematic review. Br J Anaesth. 2008;101(5):610-7.
39. Scott JC, Stanski DR. Decreased fentanyl and alfentanil dose requirements with age. A simultaneous pharmacokinetic and pharmacodynamic evaluation. J Pharmacol Exp Ther. 1987;240(1):159-66.
40. Minto CF, Schnider TW, Egan TD, et al. Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development. Anesthesiology. 1997;86(1):10-23.
41. Minto CF, Schnider TW, Shafer SL. Pharmacokinetics and pharmacodynamics of remifentanil. Anesthesiology. 1997;86(1):24-33.
42. Rivera R, Antognini JF. Perioperative drug therapy in elderly patients. Anesthesiology. 2009;110(5):1176-81.
43. Binhas M, Decailliot F, Rezaiguia-Delclaux S, et al. Comparative effect of intraoperative propacetamol versus placebo on morphine consumption after elective reduction mammoplasty under remifentanil-based anesthesia: a randomized control trial [ISRCTN71723173]. BMC Anesthesiol. 2004;4(1):6.
44. Du Manoir B, Aubrun F, Langlois M, et al. Randomized prospective study of the analgesic effect of nefopam after orthopaedic surgery. Br J Anaesth. 2003;91(6):836-41.
45. Guignard B, Coste C, Costes H, et al. Supplementing desflurane- remifentanil anesthesia with small-dose ketamine reduces perioperative opioid analgesic requirements. Anesth Analg. 2002;95(1):103-8.
46. Mao J, Price DD, Mayer DJ. Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions. Pain. 1995;62(3):259-74.
47. Bell RF, Dahl JB, Moore RA, et al. Perioperative ketamine for acute postoperative pain. Cochrane Database Syst Rev 2006 (1): CD004603.
48. Aubrun F, Monsel S, Langeron O, et al. Postoperative titration of intravenous morphine. Eur J Anaesthesiol. 2001;18:159-65.
49. Aubrun F, Monsel S, Langeron O, et al. Postoperative titration of intravenous morphine in the elderly patient. Anesthesiology. 2002;96:17-23.
50. Dahmani S, Dupont H, Mantz J, et al. Predictive factors of early morphine requirements in the post-anaesthesia care unit (PACU). Br J Anaesth. 2001;87:385-9.
51. Keita H, Tubach F, Maalouli J, et al. Age-adapted morphine titration produces equivalent analgesia and adverse effects in younger and older patients. Eur J Anaesthesiol. 2008;25(5):352-6.
52. Capdevila X, Biboulet P, Barthelet Y. Postoperative analgesia. Specificity in the elderly. Ann Fr Anesth Reanim. 1998;17(6):642-8.
53. Gagliese L, Jakson M, Ritvo P, et al. Age is not impediment to effective use of patient controlled analgesia by surgical patients. Anesthesiology. 2000;93:601-10.
54. Macintyre PE, Jarvis DA. Age is the best predictor of postoperative morphine requirements. Pain. 1995;64:357-64.
55. Keita H, Geachan N, Dahmani S, et al. Comparison between patient-controlled analgesia and subcutaneous morphine in elderly patients after total hip replacement. Br J Anaesth. 2003;90:53-7.
56. Mann C, Pouzeratte Y, Boccara G, et al. Comparison of intravenous or epidural patient-controlled analgesia in the elderly after major abdominal surgery. Anesthesiology. 2000;92(2):433-41.
57. Tramer MR, Walder B. Efficacy and adverse effects of prophylactic antiemetics during patient-controlled analgesia therapy: a quantitative systematic review. Anesth Analg. 1999;88(6):1354-61.
58. Sharrock NE. Epidural anesthetic dose responses in patients 20 to 80 years old. Anesthesiology. 1978;49(6):425-8.
59. Svircevic V, van Dijk D, Nierich AP, et al. Meta-analysis of thoracic epidural anesthesia versus general anesthesia for cardiac surgery. Anesthesiology. 2011;114(2):271-82.
60. Mann C, Pouzeratte Y, Eledjam JJ. Postoperative patient-controlled analgesia in the elderly: risks and benefits of epidural versus intravenous administration. Drugs Aging. 2003;20(5):337-45.
61. Liu S, Carpenter RL, Neal JM. Epidural anesthesia and analgesia. Their role in postoperative outcome. Anesthesiology. 1995;82(6):1474-506.
62. Kampe S, Kiencke P, Delis A, et al. The continuous epidural infusion of ropivacaine 0.1% with 0.5 microg x mL(-1) sufentanil provides effective postoperative analgesia after total hip replacement: a pilot study. Can J Anaesth. 2003;50(6):580-5.
63. Liu SS, Allen HW, Olsson GL. Patient-controlled epidural analgesia with bupivacaine and fentanyl on hospital wards: prospective experience with 1,030 surgical patients. Anesthesiology. 1998;88(3):688-95.
64. Egbert AM. Postoperative pain management in the frail elderly. Clin Geriatr Med. 1996;12(3):583-99.
65. Silvasti M, Pitkanen M. Patient-controlled epidural analgesia versus continuous epidural analgesia after total knee arthroplasty. Acta Anaesthesiol Scand. 2001;45(4):471-6.
66. Wigfull J, Welchew E. Survey of 1057 patients receiving postoperative patient-controlled epidural analgesia. Anaesthesia. 2001;56(1):70-5.
67. Gray JR, Fromme GA, Nauss LA, et al. Intrathecal morphine for post-thoracotomy pain. Anesth Analg. 1986;65(8):873-6.
68. Murphy PM, Stack D, Kinirons B, et al. Optimizing the dose of intrathecal morphine in older patients undergoing hip arthroplasty. Anesth Analg. 2003;97(6):1709-15.
69. Yamashita K, Fukusaki M, Ando Y, et al. Postoperative analgesia with minidose intrathecal morphine for bipolar hip prosthesis in extremely elderly patients. J Anesth. 2009;23(4):504-7.
70. Klein SM, Nielsen KC, Greengrass RA, et al. Ambulatory discharge after long-acting peripheral nerve blockade: 2382 blocks with ropivacaine. Anesth Analg. 2002;94(1):65-70.