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Volumn 54, Issue 5, 2013, Pages 1097-1100

Bax and Bak are required for apogossypolone, a BH3-mimetic, induced apoptosis in chronic lymphocytic leukemia cells

Author keywords

[No Author keywords available]

Indexed keywords

ANNEXIN; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; APOGOSSYPOLONE; APOPTOSIS INDUCING FACTOR; BH3 PROTEIN; GOSSYPOL; MESSENGER RNA; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; UNCLASSIFIED DRUG;

EID: 84876227417     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2012.718344     Document Type: Letter
Times cited : (13)

References (22)
  • 1
    • 55749105701 scopus 로고    scopus 로고
    • Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers
    • Pepper C, Lin TT, Pratt G, et al. Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 2008;112:3807-3817.
    • (2008) Blood , vol.112 , pp. 3807-3817
    • Pepper, C.1    Lin, T.T.2    Pratt, G.3
  • 2
    • 0032079746 scopus 로고    scopus 로고
    • Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: Correlations with in vitro and in vivo chemoresponses
    • Kitada S, Andersen J, Akar S, et al. Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with in vitro and in vivo chemoresponses. Blood 1998;91:3379-3389.
    • (1998) Blood , vol.91 , pp. 3379-3389
    • Kitada, S.1    Andersen, J.2    Akar, S.3
  • 3
    • 0031034078 scopus 로고    scopus 로고
    • Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions
    • Zhou P, Qian L, Kozopas KM, Craig RW. Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood 1997; 89: 630-643.
    • (1997) Blood , vol.89 , pp. 630-643
    • Zhou, P.1    Qian, L.2    Kozopas, K.M.3    Craig, R.W.4
  • 4
    • 0032755034 scopus 로고    scopus 로고
    • Antisense-mediated suppression of Bcl-2 highlights its pivotal role in failed apoptosis in B-cell chronic lymphocytic leukaemia
    • Pepper C, Thomas A, Hoy T, Cotter F, Bentley P. Antisense-mediated suppression of Bcl-2 highlights its pivotal role in failed apoptosis in B-cell chronic lymphocytic leukaemia. Br J Haematol 1999; 107: 611-615.
    • (1999) Br J Haematol , vol.107 , pp. 611-615
    • Pepper, C.1    Thomas, A.2    Hoy, T.3    Cotter, F.4    Bentley, P.5
  • 5
    • 32944475363 scopus 로고    scopus 로고
    • Phase i to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia
    • O'Brien SM, Cunningham CC, Golenkov AK, Turkina AG, Novick S C, Rai KR. Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia. J Clin Oncol 2005;23:7697-7702.
    • (2005) J Clin Oncol , vol.23 , pp. 7697-7702
    • O'Brien, S.M.1    Cunningham, C.C.2    Golenkov, A.K.3    Turkina, A.G.4    Novick, S.C.5    Rai, K.R.6
  • 6
    • 5244224827 scopus 로고    scopus 로고
    • X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
    • Muchmore SW, Sattler M, Liang H, et al. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature 1996;381:335-341.
    • (1996) Nature , vol.381 , pp. 335-341
    • Muchmore, S.W.1    Sattler, M.2    Liang, H.3
  • 7
    • 0141569444 scopus 로고    scopus 로고
    • Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins
    • Kitada S, Leone M, Sareth S, Zhai D, Reed JC, Pellecchia M. Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins. J Med Chem 2003;46:4259-4264.
    • (2003) J Med Chem , vol.46 , pp. 4259-4264
    • Kitada, S.1    Leone, M.2    Sareth, S.3    Zhai, D.4    Reed, J.C.5    Pellecchia, M.6
  • 8
    • 33745872296 scopus 로고    scopus 로고
    • Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins
    • Zhai D, Jin C, Satterthwait AC, Reed JC. Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins. Cell Death Differ 2006;13:1419-1421.
    • (2006) Cell Death Differ , vol.13 , pp. 1419-1421
    • Zhai, D.1    Jin, C.2    Satterthwait, A.C.3    Reed, J.C.4
  • 9
    • 1942529509 scopus 로고    scopus 로고
    • Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L)
    • Becattini B, Kitada S, Leone M, et al. Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L). Chem Biol 2004; 11: 389-395.
    • (2004) Chem Biol , vol.11 , pp. 389-395
    • Becattini, B.1    Kitada, S.2    Leone, M.3
  • 10
    • 52649179285 scopus 로고    scopus 로고
    • Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells
    • Balakrishnan K, Wierda WG, Keating MJ, Gandhi V. Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells. Blood 2008;112:1971-1980.
    • (2008) Blood , vol.112 , pp. 1971-1980
    • Balakrishnan, K.1    Wierda, W.G.2    Keating, M.J.3    Gandhi, V.4
  • 11
    • 64849104336 scopus 로고    scopus 로고
    • Design and synthesisofagossypol derivative with improved antitumor activities
    • Zhan Y, Jia G, Wu D, Xu Y, Xu L. Design and synthesisofagossypol derivative with improved antitumor activities. Arch Pharm (Weinheim) 2009;342:223-229.
    • (2009) Arch Pharm (Weinheim) , vol.342 , pp. 223-229
    • Zhan, Y.1    Jia, G.2    Wu, D.3    Xu, Y.4    Xu, L.5
  • 13
    • 40549146581 scopus 로고    scopus 로고
    • Preclinical studies of apogossypolone: A new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in follicular small cleaved cell lymphoma model
    • Arnold AA, Aboukameel A, Chen J, et al. Preclinical studies of apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in follicular small cleaved cell lymphoma model. Mol Cancer 2008; 7: 20.
    • (2008) Mol Cancer , vol.7 , pp. 20
    • Arnold, A.A.1    Aboukameel, A.2    Chen, J.3
  • 14
    • 52149098982 scopus 로고    scopus 로고
    • Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo
    • Sun Y, Wu J, Aboukameel A, et al. Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo. Cancer Biol Ter 2008;7:1418-1426.
    • (2008) Cancer Biol ter , vol.7 , pp. 1418-1426
    • Sun, Y.1    Wu, J.2    Aboukameel, A.3
  • 15
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ, et al. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990;348:334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 16
    • 0037134488 scopus 로고    scopus 로고
    • Bax and Bak independently promote cytochrome C release from mitochondria
    • Degenhardt K, Sundararajan R, Lindsten T, Tompson C, White E. Bax and Bak independently promote cytochrome C release from mitochondria. J Biol Chem 2002;277:14127-14134.
    • (2002) J Biol Chem , vol.277 , pp. 14127-14134
    • Degenhardt, K.1    Sundararajan, R.2    Lindsten, T.3    Tompson, C.4    White, E.5
  • 17
    • 16444382033 scopus 로고    scopus 로고
    • Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent
    • Choi S, Singh SV. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent. Cancer Res 2005;65:2035-2043.
    • (2005) Cancer Res , vol.65 , pp. 2035-2043
    • Choi, S.1    Singh, S.V.2
  • 18
    • 59449095496 scopus 로고    scopus 로고
    • AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance
    • Balakrishnan K, Burger JA, Wierda WG, Gandhi V. AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance. Blood 2009;113:149-153.
    • (2009) Blood , vol.113 , pp. 149-153
    • Balakrishnan, K.1    Burger, J.A.2    Wierda, W.G.3    Gandhi, V.4
  • 19
    • 44349182097 scopus 로고    scopus 로고
    • Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1
    • Zhai D, Jin C, Huang Z, Satterthwait AC, Reed JC. Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1. J Biol Chem 2008;283:9580-9586.
    • (2008) J Biol Chem , vol.283 , pp. 9580-9586
    • Zhai, D.1    Jin, C.2    Huang, Z.3    Satterthwait, A.C.4    Reed, J.C.5
  • 20
    • 38749084498 scopus 로고    scopus 로고
    • A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation
    • Lee EF, Czabotar PE, van Delft MF, et al. A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation. J Cell Biol 2008;180:341-355.
    • (2008) J Cell Biol , vol.180 , pp. 341-355
    • Lee, E.F.1    Czabotar, P.E.2    Van Delft, M.F.3
  • 21
    • 77955891885 scopus 로고    scopus 로고
    • The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer
    • Stewart ML, Fire E, Keating AE, Walensky LD. The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer. Nat Chem Biol 2010;6:595-601.
    • (2010) Nat Chem Biol , vol.6 , pp. 595-601
    • Stewart, M.L.1    Fire, E.2    Keating, A.E.3    Walensky, L.D.4
  • 22
    • 84858957737 scopus 로고    scopus 로고
    • Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation
    • Doi K, Li R, Sung SS, et al. Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation. J Biol Chem 2012;287:10224-10235.
    • (2012) J Biol Chem , vol.287 , pp. 10224-10235
    • Doi, K.1    Li, R.2    Sung, S.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.