Trisubstituted sulfonamides: A new chemotype for development of potent and selective CB2 receptor inverse agonists

ACS Medicinal Chemistry Letters

Volumn 4, Issue 4, 2013, Pages 387-392

  Ouyang, Qin ^a,b,d   Tong, Qin ^a,b   Feng, Rentian ^a,b   Myint, Kyaw Zeyar ^a,b,c   Yang, Peng ^a,b   Xie, Xiang Qun ^a,b,c  

^a School of Pharmacy   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cannabinoid receptors; inverse agonists; osteoclast inhibitors; trisubstituted sulfonamides

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 4 [4 (1,1 DIMETHYLHEPTYL) 2,6 DIMETHOXYPHENYL] 6,6 DIMETHYLBICYCLO[3.1.1]HEPT 2 EN 2 YLMETHANOL; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE;

ARTICLE; BINDING AFFINITY; BIOASSAY; DRUG DEVELOPMENT; DRUG INHIBITION; DRUG POTENCY; DRUG POTENTIATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; OSTEOCLASTOGENESIS; PRIORITY JOURNAL;

EID: 84876221205     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml3004236     Document Type: Article

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