Neurocognitive performance of a community-based sample of young people at putative ultra high risk for psychosis: Support for the processing speed hypothesis

Cognitive Neuropsychiatry

Volumn 18, Issue 1-2, 2013, Pages 9-25

  Kelleher, Ian ^a   Murtagh, Aileen ^a   Clarke, Mary C ^a   Murphy, Jennifer ^a   Rawdon, Caroline ^a   Cannon, Mary ^a  

^a BEAUMONT HOSPITAL   (Ireland)

Author keywords

At risk mental state; MATRICS; Neurocognition; Prodromal syndrome; Ultra high risk

Indexed keywords

ADOLESCENT; ARTICLE; ATTENTION; COGNITION; CONTROLLED STUDY; FEMALE; HUMAN; LEARNING; MALE; PRIORITY JOURNAL; PROBLEM SOLVING; PSYCHOSIS; SOCIAL COGNITION; STRUCTURED INTERVIEW; WORKING MEMORY;

ADOLESCENT; AROUSAL; ATTENTION; COGNITION; DISEASE PROGRESSION; EDUCATIONAL STATUS; FEMALE; HUMANS; INTERVIEW, PSYCHOLOGICAL; MALE; MEMORY; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOMOTOR PERFORMANCE; PSYCHOTIC DISORDERS; RISK; RISK FACTORS; SOCIOECONOMIC FACTORS; TRAIL MAKING TEST; VERBAL LEARNING; WECHSLER SCALES;

EID: 84876187883     PISSN: 13546805     EISSN: 14640619     Source Type: Journal    
DOI: 10.1080/13546805.2012.682363     Document Type: Article

References (55)

1. Addington, J., Cadenhead, K. S., Cannon, T.D., Cornblatt, B.,McGlashan, T. H., Perkins,D. O., ⋯ Heinssen, R. (2007). North American Prodrome Longitudinal Study: A collaborative multisite approach to prodromal schizophrenia research. Schizophrenia Bulletin, 33, 665-672. (Pubitemid 47343713)
2. Addington, J., Epstein, I., Reynolds, A., Furimsky, I., Rudy, L., Mancini, B., ⋯ Zipursky, R. B. (2008). Early detection of psychosis: Finding those at clinical high risk. Early Interventions in Psychiatry, 2, 147-153.
3. Bartels-Velthuis, A. A., van de Willige, G., Jenner, J. A., van Os, J., & Wiersma, D. (2011). Course of auditory vocal hallucinations in childhood: 5-year follow-up study. British Joournal of Psychiatry. Advance online publication. doi: 10.1192/bjp.bp.110.086918
4. Bokat, C. E., & Goldberg, T. E. (2003). Letter and category fluency in schizophrenic patients: A meta-analysis. Schizophrenia Research, 64, 73-78. (Pubitemid 37153351)
5. Bowie, C. R., Leung, W. W., Reichenberg, A., McClure, M. M., Patterson, T. L., Heaton, R. K., & Harvey, R. K. (2008). Predicting schizophrenia patients' real-world behavior with specific neuropsychological and functional capacity measures. Biological Psychiatry, 63, 505-511. (Pubitemid 351220787)
6. Brewer,W. J.,Wood, S. J., Phillips, L. J., Francey, S.M., Pantelis, C., Yung, A. R., ⋯ McGorry, P. D. (2006). Generalized and specific cognitive performance in clinical high-risk cohorts: A review highlighting potential vulnerability markers for psychosis. Schizophrenia Bulletin, 32, 538-555. (Pubitemid 43992327)
7. Bullmore, E., Frangou, S., & Murray, R. (1997). The dysplastic net hypothesis: An integration of developmental and dysconnectivity theories of schizophrenia. Schizophrenia Research, 28, 143-156. (Pubitemid 28055662)
8. Cannon, M., Moffitt, T. E., Caspi, A., Murray, R. M., Harrington, H., & Poulton, R. (2006). Neuropsychological performance at the age of 13 years and adult schizophreniform disorder: Prospective birth cohort study. British Journal of Psychiatry, 189, 463-464. (Pubitemid 44683182)
9. Cannon, T. D., Cadenhead, K., Cornblatt, B., Woods, S. W., Addington, J., Walker, E., ⋯ Heinssen, R. (2008). Prediction of psychosis in youth at high clinical risk: A multisite longitudinal study in North America. Archives of General Psychiatry, 65, 28-37.
10. Carrion, R. E., Goldberg, T. E., McLaughlin, D., Auther, A. M., Correll, C. U., & Cornblatt, B. A. (2011). Impact of neurocognition on social and role functioning in individuals at clinical high risk for psychosis. American Journal of Psychiatry, 168, 806-813.
11. Cornblatt, B. A., Lencz, T., Smith, C. W., Correll, C. U., Auther, A. M., & Nakayama, E. (2003). The schizophrenia prodrome revisited: A neurodevelopmental perspective. Schizophrenia Bulletin, 29, 633-651. (Pubitemid 38181947)
12. Cullen, A. E., Dickson, H.,West, S. A.,Morris, R.G., Mould, G. L., Hodgins, S., ⋯ Laurens,K. R. (2010). Neurocognitive performance in children aged 9-12 years who present putative antecedents of schizophrenia. Schizophrenia Research, 121, 15-23.
13. Dickinson, D. (2008). Digit symbol coding and general cognitive ability in schizophrenia: Worth another look? British Journal of Psychiatry, 193, 354-356.
14. Dickinson, D., Ramsey, M. E., & Gold, J. M. (2007). Overlooking the obvious: A meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia. Archives of General Psychiatry, 64, 532-542. (Pubitemid 46718286)
15. Friston, K., & Frith, C. (1995). Schizophrenia: A disconnection syndrome? Clinical Neuroscience, 3, 89-97.
16. Frommann, I., Pukrop, R., Brinkmeyer, J., Bechdolf, A., Ruhrmann, S., Berning, J., ⋯Wagner,M. (2011). Neuropsychological profiles in different at-risk states of psychosis: Executive control impairment in the early*and additional memory dysfunction in the late *prodromal state. Schizophrenia Bulletin, 37, 861-873.
17. Goodman, R., Ford, T., Simmons, H., Gatward, R., & Meltzer, H. (2000). Using the Strengths and Difficulties Questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. British Journal of Psychiatry, 177, 534-539. (Pubitemid 32005485)
18. Gschwandtner, U., Pfluger, M., Aston, J., Borgwardt, S., Drewe, M., Stieglitz, R. D., & Riecher-Rossler, A. (2006). Fine motor function and neuropsychological deficits in individuals at risk for schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, 256, 201-206. (Pubitemid 43989502)
19. Hawkins, K. A., Addington, J., Keefe, R. S., Christensen, B., Perkins, D. O., Zipurksy, R., ⋯ McGlashan, T. H. (2004). Neuropsychological status of subjects at high risk for a first episode of psychosis. Schizophrenia Research, 67, 115-122. (Pubitemid 38251441)
20. Henry, J. D., & Crawford, J. R. (2005). A meta-analytic review of verbal fluency deficits in schizophrenia relative to other neurocognitive deficits. Cognitive Neuropsychiatry, 10, 1-33. (Pubitemid 40460674)
21. Holmen, A., Juuhl-Langseth, M., Thormodsen, R., Melle, I., & Rund, B. R. (2010). Neuropsychological profile in early-onset schizophrenia-spectrum disorders: Measured with the MATRICS battery. Schizophrenia Bulletin, 36, 852-859.
22. Johnson-Selfridge, M., & Zalewski, C. (2001). Moderator variables of executive functioning in schizophrenia: Meta-analytic findings. Schizophrenia Bulletin, 27, 305-316. (Pubitemid 33644305)
23. Kaufman, J., Birmaher, B., Brent, D., Rao, U., & Ryan, N. (1996). The Schedule for Affective Disorders and Schizophrenia for School-aged children, Present and Lifetime Versions. Pittsburgh, PA: University of Pittsburgh, Western Psychiatric Institute and Clinic.
24. Keefe, R. S., Perkins, D. O., Gu, H., Zipursky, R. B., Christensen, B. K., & Lieberman, J. A. (2006). A longitudinal study of neurocognitive function in individuals at-risk for psychosis. Schizophrenia Research, 88, 26-35. (Pubitemid 44693238)
25. Kelleher, I., & Cannon, M. (2011). Psychotic-like experiences in the general population: Characterizing a high-risk group for psychosis. Psychological Medicine, 41, 1-6.
26. Kelleher, I., Connor, D., Clarke, M. C., Devlin, N., Harley, M., & Cannon, M. (2012). Prevalence of psychotic symptoms in childhood and adolescence: A systematic review and meta-analysis of population-based studies. Psychological Medicine. Advance online publication. doi: 10.1017/ S0033291711002960
27. Kelleher, I., Harley, M., Murtagh, A., & Cannon, M. (2011). Are screening instruments valid for psychotic-like experiences? A validation study of screening questions for psychotic-like experiences using in-depth clinical interview. Schizophrenia Bulletin, 37, 362-369.
28. Kelleher, I., Keeley, H., Corcoran, P., Lynch, F., Fitzpatrick, C., Devlin, N., ⋯ Cannon, M. (2012). Clinicopathological significance of psychotic experiences in non-psychotic young people: Evidence from 4 population studies. British Journal of Psychiatry. Advance online publication. doi:10.1192/bjp.bp.111.101543
29. Kelleher, I., Lynch, F., Harley,M., Molloy, C., Roddy, S., Fitzpatrick, C., et al. (in press). Psychotic symptoms in adolescence index risk for suicidal behaviour: Findings from two populationbased case-control clinical interview studies. Archives of General Psychiatry.
30. Kelleher, I., Murtagh, A., Molloy, C., Roddy, S., Clarke, M. C., Harley, M., & Cannon, M. (2012). Identification and characterization of prodromal risk syndromes in young adolescents in the community: A population-based clinical interview study. Schizophrenia Bulletin, 38, 239-246.
31. Kern, R. S., Nuechterlein, K. H., Green, M. F., Baade, L. E., Fenton, W. S., Gold, J. M., ⋯ Marder, S. R. (2008). The MATRICS Consensus Cognitive Battery, Part 2: Co-norming and standardization. American Journal of Psychiatry, 165, 214-220. (Pubitemid 351704521)
32. Klosterkotter, J., Hellmich, M., Steinmeyer, E. M., & Schultze-Lutter, F. (2001). Diagnosing schizophrenia in the initial prodromal phase. Archives of General Psychiatry, 58, 158-164. (Pubitemid 32142753)
33. Knowles, E. E., David, A. S., & Reichenberg, A. (2010). Processing speed deficits in schizophrenia: Reexamining the evidence. American Journal of Psychiatry, 167, 828-835.
34. Laws, K. R. (1999). A meta-analytic review of Wisconsin Card Sort studies in schizophrenia: General intellectual deficit in disguise? Cognitive Neuropsychiatry, 4, 1-30; discussion 31-35.
35. Lee, J., & Park, S. (2005). Working memory impairments in schizophrenia: A meta-analysis. Journal of Abnormal Psychology, 114, 599-611. (Pubitemid 41746997)
36. Lynch, F., Mills, C., Daly, I., & Fitzpatrick, C. (2006). Challenging times: Prevalence of psychiatric disorders and suicidal behaviours in Irish adolescents. Journal of Adolescence, 29, 555-573. (Pubitemid 44070564)
37. McGlashan, T. H., Miller, T. J., & Woods, S. W. (2001). Pre-onset detection and intervention research in schizophrenia psychoses: Current estimates of benefit and risk. Schizophrenia Bulletin, 27, 563-570. (Pubitemid 34093243)
38. Merikangas, K. R., He, J. P., Brody, D., Fisher, P. W., Bourdon, K., & Koretz, D. S. (2010). Prevalence and treatment of mental disorders among US children in the 2001-2004 NHANES. Pediatrics, 125, 75-81.
39. Mesholam-Gately, R. I., Giuliano, A. J., Goff, K. P., Faraone, S. V., & Seidman, L. J. (2009). Neurocognition in first-episode schizophrenia: A meta-analytic review. Neuropsychology, 23, 315-336.
40. Miller, T. J., McGlashan, T. H., Rosen, J. L., Cadenhead, K., Cannon, T., Ventura, J., ⋯Wood, S.W. (2003). Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: Predictive validity, interrater reliability, and training to reliability. Schizophrenia Bulletin, 29, 703-715. (Pubitemid 38181951)
41. Mukkala, S., Ilonen, T., Nordstrom, T., Miettunen, J., Loukkola, J., Barnett, J. H., ⋯ Veijoka, J. (2011). Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort. Journal of Clinical and Experimental Neuropsychology, 33, 385-394.
42. Niendam, T. A., Bearden, C. E., Johnson, J. K., McKinley, M., Loewy, R., O'Brien, M., ⋯ Cannon, T. D. (2006). Neurocognitive performance and functional disability in the psychosis prodrome. Schizophrenia Research, 84, 100-111. (Pubitemid 43732484)
43. Nuechterlein, K. H., Green, M. F., Kern, R. S., Baade, L. E., Barch, D. M., Cohen, J. D., ⋯ Marder, S. R. (2008). The MATRICS Consensus Cognitive Battery, Part 1: Test selection, reliability, and validity. American Journal of Psychiatry, 165, 203-213. (Pubitemid 351704520)
44. Poulton, R., Caspi, A., Moffitt, T. E., Cannon, M., Murray, R., & Harrington, H. (2000). Children's self-reported psychotic symptoms and adult schizophreniform disorder: A 15-year longitudinal study. Archives of General Psychiatry, 57, 1053-1058.
45. Pukrop, R., & Klosterkotter, J. (2010). Neurocognitive indicators of clinical high-risk states for psychosis: A critical review of the evidence. Neurotoxicity Research, 18, 272-286.
46. Pukrop, R., Schultze-Lutter, F., Ruhrmann, S., Brockhaus-Dumke, A., Tendolkar, I., Bechdolf, A., ⋯ Klosterkotter, J. (2006). Neurocognitive functioning in subjects at risk for afirst episode of psychosis compared with first-and multiple-episode schizophrenia. Journal of Clinical and Experimental Neuropsychology, 28, 1388-1407. (Pubitemid 44578245)
47. Rodriguez-Sanchez, J. M., Crespo-Facorro, B., Gonzalez-Blanch, C., Perez-Iglesias, R., & Vazquez-Barquero, J. L. (2007). Cognitive dysfunction in first-episode psychosis: The processing speed hypothesis. British Journal of Psychiatry, 51(Suppl.), s107-s110. (Pubitemid 350273198)
48. Seidman, L. J., Giuliano, A. J., Meyer, E. C., Addington, J., Cadenhead, K. S., Cannon, T. D., ⋯ North American Prodome Longitudinal Study (NAPLS) Group. (2010). Neuropsychology of the prodrome to psychosis in the NAPLS consortium: Relationship to family history and conversion to psychosis. Archives of General Psychiatry, 67, 578-588.
49. Turken, A., Whitfield-Gabrieli, S., Bammer, R., Baldo, J. V., Dronkers, N. F., & Gabrieli, J. D. (2008). Cognitive processing speed and the structure of white matter pathways: Convergent evidence from normal variation and lesion studies. Neuroimage, 42, 1032-1044.
50. van Os, J., Linscott, R. J.,Myin-Germeys, I., Delespaul, P., & Krabbendam, L. (2009). A systematic review and meta-analysis of the psychosis continuum: Evidence for a psychosis pronenesspersistence-impairment model of psychotic disorder. Psychological Medicine, 39, 179-195.
51. Weinberger, D., Berman, K., Suddath, R., & Torrey, E. (1992). Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: A magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. American Journal of Psychiatry, 149, 890-897.
52. Wilkinson, G., & Robertson, G. (2005). Wide Range Achievement Test (4th ed.). Lutz, FL: Psychological Assessment Resources, Inc.
53. Woods, S. W., Addington, J., Cadenhead, K. S., Cannon, T. D., Cornblatt, B. A., Heinssen, R., ⋯ McGlashan, T. H. (2009). Validity of the prodromal risk syndrome for first psychosis: Findings from the North American Prodrome Longitudinal Study. Schizophrenia Bulletin, 35, 894-908.
54. Yung, A. R.,McGorry, P. D., McFarlane, C. A., Jackson, H. J., Patton, G. C., & Rakkar, A. (1996). Monitoring and care of young people at incipient risk of psychosis. Schizophrenia Bulletin, 22, 283-303. (Pubitemid 26174575)
55. Yung, A. R., Phillips, L. J., Yuen, H. P., Francey, S. M., McFarlane, C. A., Hallgren, M., ⋯ McGorry, P. D. (2003). Psychosis prediction: 12-month follow up of a high-risk ("prodromal") group. Schizophrenia Research, 60, 21-32. (Pubitemid 36015785)