Mechanisms underlying protective effects of trimetazidine on endothelial progenitor cells biological functions against H2O2-induced injury: Involvement of antioxidation and Akt/eNOS signaling pathways

European Journal of Pharmacology

Volumn 707, Issue 1-3, 2013, Pages 87-94

  Wu, Qinqin ^a   Qi, Benling ^a   Liu, Yun ^a   Cheng, Bei ^a   Liu, Lihua ^a   Li, Yuanyuan ^a   Wang, Qian ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Akt eNOS signaling pathway; Endothelial progenitor cells; Ischemic heart disease; Oxidative stress; Trimetazidine

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; MALONALDEHYDE; NITRIC OXIDE; PROTEIN KINASE B; SUPEROXIDE DISMUTASE; TRICIRIBINE; TRIMETAZIDINE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIAL PROGENITOR CELL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART PROTECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; ISCHEMIC HEART DISEASE; OXIDATIVE STRESS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL CORD BLOOD;

ANTIOXIDANTS; CARDIOTONIC AGENTS; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; MALONDIALDEHYDE; MYOCARDIAL ISCHEMIA; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; RIBONUCLEOSIDES; SIGNAL TRANSDUCTION; STEM CELLS; SUPEROXIDE DISMUTASE; TRIMETAZIDINE;

EID: 84876176728     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.03.027     Document Type: Article

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