Association of high-sensitivity C-reactive protein with cardiometabolic risk factors and micronutrient deficiencies in adults of Ouagadougou, Burkina Faso

British Journal of Nutrition

Volumn 109, Issue 7, 2013, Pages 1266-1275

  Zeba, Augustin N ^a,b   Delisle, Hélène F ^a   Rossier, Clémentine ^c   Renier, Genevieve ^d  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Institut de Recherche en Sciences de la Santé   (Burkina Faso)

^c UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

^d CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Adults; Burkina Faso; Cardiometabolic risk factors; Inflammation; Micronutrient deficiencies

Indexed keywords

C REACTIVE PROTEIN; FERRITIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; RETINOL; TRIACYLGLYCEROL;

ABDOMINAL OBESITY; ADULT; ANEMIA; ARTICLE; BODY FAT; BODY HEIGHT; BODY MASS; BODY WEIGHT; CARDIOMETABOLIC RISK; CHINA; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DISORDERS OF LIPID METABOLISM; EDUCATIONAL STATUS; FEMALE; FERRITIN BLOOD LEVEL; HIGH RISK POPULATION; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPERTRIACYLGLYCEROLEMIA; INCOME; INSULIN RESISTANCE; MALE; NUTRITIONAL DEFICIENCY; NUTRITIONAL STATUS; PROTEIN BLOOD LEVEL; RETINOL DEFICIENCY; RISK ASSESSMENT; WAIST CIRCUMFERENCE;

ADIPOSITY; ADULT; BIOLOGICAL MARKERS; BODY MASS INDEX; BURKINA FASO; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDIES; DEVELOPED COUNTRIES; DIET; FEMALE; HUMANS; MALE; METABOLIC SYNDROME X; MICRONUTRIENTS; MIDDLE AGED; OBESITY, ABDOMINAL; PREVALENCE; RISK FACTORS; SOCIOECONOMIC FACTORS; URBAN HEALTH; VITAMIN A DEFICIENCY;

EID: 84876159523     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512003182     Document Type: Article

References (75)

1. Cesari M, Penninx BW, Newman AB, et al. (2003) Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation 108, 2317-2322.
2. Han TS, Sattar N, Williams K, et al. (2002) Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study. Diabetes Care 25, 2016-2021.
3. Ridker PM, Cushman M, Stampfer MJ, et al. (1997) Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 336, 973-979.
4. Ridker PM, Hennekens CH, Buring JE, et al. (2000) C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342, 836-843.
5. Danesh J, Whincup P, Walker M, et al. (2000) Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. BMJ 321, 199-204.
6. Pai JK, Pischon T, Ma J, et al. (2004) Inflammatory markers and the risk of coronary heart disease in men and women. N Engl J Med 351, 2599-2610.
7. Benzaquen LR, Yu H and Rifai N (2002) High sensitivity C-reactive protein: an emerging role in cardiovascular risk assessment. Crit Rev Clin Lab Sci 39, 459-497.
8. Ridker PM (2009) Testing the inflammatory hypothesis of atherothrombosis: scientific rationale for the cardiovascular inflammation reduction trial (CIRT). J Thromb Haemost 7, Suppl. 1, 332-339.
9. Kaptoge S, Di Angelantonio E, Lowe G, et al. (2010) C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 375, 132-140.
10. Danesh J, Wheeler JG, Hirschfield GM, et al. (2004) C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med 350, 1387-1397.
11. Miller M, Zhan M and Havas S (2005) High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: the Third National Health and Nutrition Examination Survey. Arch Intern Med 165, 2063-2068.
12. Saito M, Ishimitsu T, Minami J, et al. (2003) Relations of plasma high-sensitivity C-reactive protein to traditional cardiovascular risk factors. Atherosclerosis 167, 73-79.
13. Hurt N, Smith T, Teuscher T, et al. (1994) Do high levels of C-reactive protein in Tanzanian children indicate malaria morbidity? Clin Diagn Lab Immunol 1, 437-444.
14. Imrie H, Fowkes FJ, Michon P, et al. (2007) Low prevalence of an acute phase response in asymptomatic children from a malaria-endemic area of Papua New Guinea. Am J Trop Med Hyg 76, 280-284.
15. Abraham K, Muller C, Gruters A, et al. (2003) Minimal inflammation, acute phase response and avoidance of misclassification of vitamin A and iron status in infants - importance of a high-sensitivity C-reactive protein (CRP) assay. Int J Vitam Nutr Res 73, 423-430.
16. Schweigert FJ (2001) Inflammation-induced changes in the nutritional biomarkers serum retinol and carotenoids. Curr Opin Clin Nutr Metab Care 4, 477-481.
17. Stephensen CB and Gildengorin G (2000) Serum retinol, the acute phase response, and the apparent misclassification of vitamin A status in the third National Health and Nutrition Examination Survey. Am J Clin Nutr 72, 1170-1178.
18. World Health Organization (2003) Diet, Nutrition and the Prevention of Chronic Diseases. Joint WHO/FAO Expert Consultation. WHO Technical Report Series no. 916. Geneva: WHO.
19. Abegunde DO, Mathers CD, Adam T, et al. (2007) The burden and costs of chronic diseases in low-income and middle-income countries. Lancet 370, 1929-1938.
20. Misra A and Khurana L (2008) Obesity and the metabolic syndrome in developing countries. J Clin Endocrinol Metab 93, S9-S30.
21. Abubakari AR, Lauder W, Agyemang C, et al. (2008) Prevalence and time trends in obesity among adult West African populations: a meta-analysis. Obes Rev 9, 297-311.
22. Abubakari AR, Lauder W, Jones MC, et al. (2009) Prevalence and time trends in diabetes and physical inactivity among adult West African populations: the epidemic has arrived. Public Health 123, 602-614.
23. Zeba AN, Delisle HF, Renier G, et al. (2012) The double burden of malnutrition and cardiometabolic risk widens the gender and socio-economic health gap: a study among adults in Burkina Faso (West Africa). Public Health Nutr (epublication ahead of print version 30 March 2012).
24. City Development Strategy (2007) Etude diagnostique de l'agglomération de Ouagadougou. Ouagadougou: CDS.
25. Niakara A, Fournet F, Gary J, et al. (2007) Hypertension, urbanization, social and spatial disparities: a cross-sectional population-based survey in a West African urban environment (Ouagadougou, Burkina Faso). Trans R Soc Trop Med Hyg 101, 1136-1142.
26. Direction de la Nutrition (2006) Analyse complémentaire de la situation nutritionnelle au Burkina Faso: Rapport final. Ouagadougou: Ministére de la Santé du Burkina Faso.
27. Lohman T, Roche A and Martorell R (1988) Anthropometric Standardization Reference Manual. Champaign, IL: Human Kinetics Books.
28. World Health Organization (2000) Obesity: Preventing and Managing the Global Epidemic. Report of a WHO Consultation on Obesity. WHO Technical Report Series no. Geneva: WHO.
29. Alberti KG, Eckel RH, Grundy SM, et al. (2009) Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 120, 1640-1645.
30. Sun SS, Chumlea WC, Heymsfield SB, et al. (2003) Development of bioelectrical impedance analysis prediction equations for body composition with the use of a multicomponent model for use in epidemiologic surveys. Am J Clin Nutr 77, 331-340.
31. Jackson AS, Stanforth PR, Gagnon J, et al. (2002) The effect of sex, age and race on estimating percentage body fat from body mass index: The Heritage Family Study. Int J Obes Relat Metab Disord 26, 789-796.
32. Pearson TA, Mensah GA, Alexander RW, et al. (2003) Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107, 499-511.
33. Ridker PM, Wilson PW and Grundy SM (2004) Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation 109, 2818-2825.
34. World Health Organization (1999) The Metabolic Syndrome. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Part 1: Diagnosis and Classification of Diabetes Mellitus. Geneva: WHO.
35. Millan J, Pinto X, Munoz A, et al. (2009) Lipoprotein ratios: physiological significance and clinical usefulness in cardiovascular prevention. Vasc Health Risk Manag 5, 757-765.
36. Matthews DR, Hosker JP, Rudenski AS, et al. (1985) Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419.
37. World Health Organization (2009) Global Prevalence of Vitamin A Deficiency in Populations at Risk 1995-2005. WHO Global Database on Vitamin A Deficiency. Geneva: WHO.
38. World Health Organization (2004) Assessing the Iron Status of Populations: Including Literature Reviews: Report of a Joint WHO/CDC and Prevention Technical Consultation on the Assessment of Iron Status at the Population Level, 6-8 April 2004. Geneva: WHO.
39. Kao TW, Lu IS, Liao KC, et al. (2009) Associations between body mass index and serum levels of C-reactive protein. S Afr Med J 99, 326-330.
40. Santos AC, Lopes C, Guimaraes JT, et al. (2005) Central obesity as a major determinant of increased high-sensitivity C-reactive protein in metabolic syndrome. Int J Obes (Lond) 29, 1452-1456.
41. Hwang JJ, Li HY, Shieh GJ, et al. (2008) Illustrating the roles of C-reactive protein in the development of the metabolic syndrome in women - a cross-racial validation. Nutr Metab Cardiovasc Dis 18, 671-677.
42. Nakamura H, Ito H, Egami Y, et al. (2008) Waist circumference is the main determinant of elevated C-reactive protein in metabolic syndrome. Diabetes Res Clin Pract 79, 330-336.
43. Brooks GC, Blaha MJ and Blumenthal RS (2010) Relation of C-reactive protein to abdominal adiposity. Am J Cardiol 106, 56-61.
44. McDade TW, Rutherford JN, Adair L, et al. (2008) Adiposity and pathogen exposure predict C-reactive protein in Filipino women. J Nutr 138, 2442-2447.
45. Park HS, Park JY and Yu R (2005) Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-a and IL-6. Diabetes Res Clin Pract 69, 29-35.
46. Visser M, Bouter LM, McQuillan GM, et al. (1999) Elevated C-reactive protein levels in overweight and obese adults. JAMA 282, 2131-2135.
47. Lapice E, Maione S, Patti L, et al. (2009) Abdominal adiposity is associated with elevated C-reactive protein independent of BMI in healthy nonobese people. Diabetes Care 32, 1734-1736.
48. Jeemon P, Prabhakaran D, Ramakrishnan L, et al. (2011) Association of high sensitive C-reactive protein (hsCRP) with established cardiovascular risk factors in the Indian population. Nutr Metab (Lond) 8, 19.
49. Olsen MH, Christensen MK, Hansen TW, et al. (2006) High-sensitivity C-reactive protein is only weakly related to cardiovascular damage after adjustment for traditional cardiovascular risk factors. J Hypertens 24, 655-661.
50. Rocha VZ and Libby P (2009) Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol 6, 399-409.
51. Ridker PM, Rifai N, Rose L, et al. (2002) Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 347, 1557-1565.
52. Pischon T, Mohlig M, Hoffmann K, et al. (2007) Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels. Eur J Epidemiol 22, 429-438.
53. Everett BM, Kurth T, Buring JE, et al. (2006) The relative strength of C-reactive protein and lipid levels as determinants of ischemic stroke compared with coronary heart disease in women. J Am Coll Cardiol 48, 2235-2242.
54. Rockhill B, Newman B and Weinberg C (1998) Use and misuse of population attributable fractions. Am J Public Health 88, 15-19.
55. Zoratti R (1998) A review on ethnic differences in plasma triglycerides and high-density-lipoprotein cholesterol: is the lipid pattern the key factor for the low coronary heart disease rate in people of African origin? Eur J Epidemiol 14, 9-21.
56. Blake GJ, Rifai N, Buring JE, et al. (2003) Blood pressure, C-reactive protein, and risk of future cardiovascular events. Circulation 108, 2993-2999.
57. McLaughlin T, Abbasi F, Lamendola C, et al. (2002) Differentiation between obesity and insulin resistance in the association with C-reactive protein. Circulation 106, 2908-2912.
58. Xu JW, Morita I, Ikeda K, et al. (2007) C-reactive protein suppresses insulin signaling in endothelial cells: role of spleen tyrosine kinase. Mol Endocrinol 21, 564-573.
59. Donath MY and Shoelson SE (2011) Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 11, 98-107.
60. Goldfine AB, Fonseca V and Shoelson SE (2011) Therapeutic approaches to target inflammation in type 2 diabetes. Clin Chem 57, 162-167.
61. Heilbronn LK and Campbell LV (2008) Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity. Curr Pharm Des 14, 1225-1230.
62. Oliver E, McGillicuddy F, Phillips C, et al. (2010) The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA. Proc Nutr Soc 69, 232-243.
63. Shoelson SE, Lee J and Goldfine AB (2006) Inflammation and insulin resistance. J Clin Invest 116, 1793-1801.
64. International Diabetes Federation (2009) Diabetes Atlas, 4th ed. Brussels: IDF.
65. Brazionis L, Walker KZ, Itsiopoulos C, et al. (2011) Plasma retinol: a novel marker for cardiovascular disease mortality in Australian adults. Nutr Metab Cardiovasc Dis (epublication ahead of print version 25 November 2011).
66. Stephensen CB, Alvarez JO, Kohatsu J, et al. (1994) Vitamin A is excreted in the urine during acute infection. Am J Clin Nutr 60, 388-392.
67. Rosales FJ and Ross AC (1998) A low molar ratio of retinol binding protein to transthyretin indicates vitamin A deficiency during inflammation: studies in rats and a posterior analysis of vitamin A-supplemented children with measles. J Nutr 128, 1681-1687.
68. Sung KC, Kang JH and Shin HS (2007) Relationship of cardiovascular risk factors and serum ferritin with C-reactive protein. Arch Med Res 38, 121-125.
69. Williams MJ, Poulton R and Williams S (2002) Relationship of serum ferritin with cardiovascular risk factors and inflammation in young men and women. Atherosclerosis 165, 179-184.
70. Cepeda-Lopez AC, Osendarp SJ, Melse-Boonstra A, et al. (2011) Sharply higher rates of iron deficiency in obese Mexican women and children are predicted by obesityrelated inflammation rather than by differences in dietary iron intake. Am J Clin Nutr 93, 975-983.
71. Zimmermann MB, Zeder C, Muthayya S, et al. (2008) Adiposity in women and children from transition countries predicts decreased iron absorption, iron deficiency and a reduced response to iron fortification. Int J Obes (Lond) 32, 1098-1104.
72. Aeberli I, Hurrell RF and Zimmermann MB (2009) Overweight children have higher circulating hepcidin concentrations and lower iron status but have dietary iron intakes and bioavailability comparable with normal weight children. Int J Obes (Lond) 33, 1111-1117.
73. Cepeda-Lopez AC, Aeberli I and Zimmermann MB (2010) Does obesity increase risk for iron deficiency? A review of the literature and the potential mechanisms. Int J Vitam Nutr Res 80, 263-270.
74. Tussing-Humphreys LM, Nemeth E, Fantuzzi G, et al. (2010) Elevated systemic hepcidin and iron depletion in obese premenopausal females. Obesity (Silver Spring) 18, 1449-1456.
75. Aderibigbe OR, Pisa PT, Mamabolo RL, et al. (2011) The relationship between indices of iron status and selected anthropometric cardiovascular disease risk markers in an African population: the THUSA study. Cardiovasc J Afr 22, 249-256.