Naive T-cells in myelodysplastic syndrome display intrinsic human telomerase reverse transcriptase (hTERT) deficiency

Leukemia

Volumn 27, Issue 4, 2013, Pages 897-906

  Yang, L ^a,b   Mailloux, A ^a   Rollison, D E ^a   Painter, J S ^a   MacIejewski, J ^c   Paquette, R L ^d   Loughran, T P ^e   McGraw, K ^a   Makishima, H ^c   Radhakrishnan, R ^a   Wei, S ^a   Ren, X ^b   Komrokji, R ^a   List, A F ^a   Epling Burnette, P K ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c Cleveland Cancer Center   (United States)

^d UCLA MEDICAL CENTER   (United States)

^e PENN STATE CANCER INSTITUTE   (United States)

Author keywords

bone marrow failure; myelodysplastic syndrome; T lymphocyte; telomere; transcription

Indexed keywords

MESSENGER RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGE; AGED; ARTICLE; CD3+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INDUCTION; FEMALE; GENE DELETION; GENE EXPRESSION; GENE MUTATION; HOMEOSTASIS; HUMAN; HUMAN CELL; MALE; MEMORY T LYMPHOCYTE; MOLECULAR MECHANICS; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION; TARGETED GENE REPAIR; TELOMERE; TELOMERE HOMEOSTASIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BROMODEOXYURIDINE; CASE-CONTROL STUDIES; CELL PROLIFERATION; FEMALE; HUMANS; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; T-LYMPHOCYTES; TELOMERASE; TELOMERE; YOUNG ADULT;

EID: 84876151219     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.300     Document Type: Article

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