Novel G protein-coupled oestrogen receptor GPR30 shows changes in mRNA expression in the rat brain over the oestrous cycle

NeuroSignals

Volumn 21, Issue 1-2, 2013, Pages 14-27

  Spary, Emma J ^a   Chapman, Sally E ^a   Sinfield, John K ^a   Maqbool, Azhar ^a   Kaye, Jean ^a   Batten, Trevor F C ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

GPR30; Hypothalamus; Nucleus tractus solitarius; Oestrogen receptor; Oestrous cycle; Ovariectomy; Periaqueductal gray; Ventrolateral medulla

Indexed keywords

G PROTEIN COUPLED RECEPTOR 30; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTONOMIC INNERVATION; AUTONOMIC NERVE; BRAIN; CATECHOLAMINE NERVE CELL; CONTROLLED STUDY; ESTRUS CYCLE; FEMALE; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; METESTRUS; NEUROTRANSMITTER RELEASE; NITRERGIC NERVE CELL; NONHUMAN; OVARIECTOMY; PERIAQUEDUCTAL GRAY MATTER; PHENOTYPE; PROESTRUS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEROTONINERGIC NERVE CELL; SOLITARY TRACT NUCLEUS; THALAMUS VENTRAL NUCLEUS;

EID: 84876146700     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000333296     Document Type: Article

References (53)

1. Cornil CA, Ball GF, Balthazart J: Functional significance of the rapid regulation of brain estrogen action: Where do the estrogens come from? Brain Res 2006; 1126: 2-26
2. Maggi A, Ciana P, Belcredito S, Vegeto E: Estrogens in the nervous system: Mechanisms and nonreproductive functions. Annu Rev Physiol 2004; 66: 291-313
3. Saleh MC, Connell BJ, Saleh TM: Autonomic and cardiovascular reflex responses to central estrogen injection in ovariectomized female rats. Brain Res 2000; 879: 105-114
4. Saleh MC, Connell BJ, Saleh TM: Medullary and intrathecal injections of 17-estradiol in male rats. Brain Res 2000; 867: 200-209
5. Saleh TM, Connell BJ, Saleh MC: Acute injection of 17-estradiol enhances cardiovascular reflexes and autonomic tone in ovariectomized female rats. Auton Neurosci 2000; 84: 78-88
6. Spyer KM: Central nervous mechanisms contributing to cardiovascular control. J Physiol (Lond) 1994; 474: 1-19
7. Loewy AD: Central autonomic pathways; in Loewy AD, Spyer KM (eds): Central Regulation of Autonomic Functions. New York, Oxford University Press, 1990, pp 88-103
8. Dampney RA, Horiuchi J, Killinger S, Sheriff MJ, Tan PS, McDowall LM: Long-term regulation of arterial blood pressure by hypothalamic nuclei: Some critical questions. Clin Exp Pharmacol Physiol 2005; 32: 419-425
9. Lovick TA: The periaqueductal gray-rostral medulla connection in the defence reaction: efferent pathways and descending control mechanisms. Behav Brain Res 1993; 58: 19-25
10. Carrive P: The periaqueductal gray and defensive behavior: functional representation and neuronal organization. Behav Brain Res 1993; 58: 27-47
11. Takezawa H, Hayashi H, Sano H, Saito H, Ebihara S: Circadian and estrous cycle-dependent variations in blood pressure and heart rate in female rats. Am J Physiol 1994; 267:R1250-R1256
12. Sasaki T, Ohno Y, Otsuka K, Suzawa T, Suzuki H, Saruta T: Oestrogen attenuates the increases in blood pressure and platelet aggregation in ovariectomized and salt-loaded Dahl salt-sensitive rats. J Hypertens 2000; 18: 911-917
13. Goldman RK, Azar AS, Mulvaney JM, Hinojosa-Laborde C, Haywood JR, Brooks VL: Baroreflex sensitivity varies during the rat estrous cycle: Role of gonadal steroids. Am J Physiol Regul Integr Comp Physiol 2009; 296:R1419-R1426
14. Kuo TBJ, Lai CT, Hsu F-C, Tseng Y-J, Li JY, Shieh S-C, Tsai CJ, Yang CCH: Cardiac neural regulation oscillates with the estrous cycle in freely moving female rats: The role of endogenous estrogen. Endocrinology 2010; 151: 2613-2621
15. Spary EJ, Maqbool A, Batten TF: Oestrogen receptors in the central nervous system and evidence for their role in the control of cardiovascular function. J Chem Neuroanat 2009; 38: 185-196
16. Pietras RJ, Szego CM: Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells. Nature 1977; 265: 69-72
17. Thomas P, Pang Y, Filardo EJ, Dong J: Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 2005; 146: 624-632
18. Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER: A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005; 307: 1625-1630
19. Funakoshi T, Yanai A, Shinoda K, Kawano MM, Mizukami Y: G protein-coupled receptor is an estrogen receptor in the plasma membrane. Biochem Biophys Res Commun 2006; 346: 904-910
20. Brailoiu E, Dun SL, Brailoiu GC, Mizuo K, Sklar LA, Oprea TI, Prossnitz ER, Dun NJ: Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. J Endocrinol 2007; 193: 311-321
21. Sakamoto H, Matsuda K, Hosokawa K, Nishi M, Morris JF, Prossnitz ER, Kawata M: Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. Endocrinology 2007; 148: 5842-5850
22. Matsuda K, Sakamoto H, Mori H, Hosokawa K, Kawamura A, Itose M, Nishi M, Prossnitz ER, Kawata M: Expression and intracellular distribution of the G protein-coupled receptor
23. in rat hippocampal formation. Neurosci Lett 2008; 441: 94-99
24. Spary EJ, Maqbool A, Batten TFC: Oestrogen receptors in the central nervous system and evidence for their role in the control of cardiovascular function. J Chem Neuroanat 2009; 38: 185-196
25. Zhou Y, Shughrue PJ, Dorsa DM: Estrogen receptor protein is differentially regulated in the preoptic area of the brain and in the uterus during the rat estrous cycle. Neuroendocrinology 1995; 61: 276-283
26. Haywood SA, Simonian SX, van der Beek EM, Bicknell RJ, Herbison AE: Fluctuating estrogen and progesterone receptor expression in brainstem norepinephrine neurons through the rat estrous cycle. Endocrinology 1999; 140: 3255-3263
27. Shughrue PJ, Bushnell CD, Dorsa DM: Estrogen receptor messenger ribonucleic acid in female rat brain during the estrous cycle: A comparison with ovariectomized females and intact males. Endocrinology 1992; 131: 381-388
28. Spary EJ, Maqbool A, Batten TFC: Changes in oestrogen receptor expression in the nucleus of the solitary tract of the rat over the oestrus cycle and following ovariectomy. J Neuroendocrinol 2010; 22: 492-502
29. Wang C, Prossnitz ER, Roy SK: Expression of G protein-coupled receptor 30 in the hamster ovary: differential regulation by gonadotropins and steroid hormones. Endocrinology 2007; 148: 4853-4864
30. Spary EJ, Chapman SE, Maqbool A, Batten TFC: Novel oestrogen receptor GPR30: brain localisation and changes in expression during the rat oestrus cycle. Auton Neurosci 2007; 135: 61-62
31. Saha S, Spary EJ, Maqbool A, Asipu A, Corbett EK, Batten TF: Increased expression of AMPA receptor subunits in the nucleus of the solitary tract in the spontaneously hypertensive rat. Brain Res Mol Brain Res 2004; 121: 37-49
32. Paxinos G, Kus L, Ashwell KWS, Watson C: Chemoarchitectonic Atlas of the Rat Forebrain, ed 1. San Diego, Academic Press, 1999
33. Paxinos G, Carrive P, Wang H, Wang P-Y: Chemoarchitectonic atlas of the rat brainstem, ed 1. San Diego, Academic Press, 1999
34. Xu H, Qin S, Carrasco GA, Dai Y, Filardo EJ, Prossnitz ER, Battaglia G, DonCarlos LL, Muma NA: Extranuclear estrogen receptor GPR30 regulates serotonin function in rat hypothalamus. Neuroscience 2009; 158: 1599-1607
35. Hazell GG, Yao ST, Roper JA, Prossnitz ER, O'Carroll AM, Lolait SJ: Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues. J Endocrinol 2009; 202: 223-236
36. Mårtensson UE, Salehi SA, Windahl S, Gomez MF, Swärd K, Daszkiewicz-Nilsson J, Wendt A, Andersson N, Hellstrand P, Grände PO, Owman C, Rosen CJ, Adamo ML, Lundquist I, Rorsman P, Nilsson BO, Ohlsson C, Olde B, Leeb-Lundberg LM: Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice. Endocrinology 2009; 150: 687-698
37. Dun SL, Brailoiu GC, Gao X, Brailoiu E, Arterburn JB, Prossnitz ER, Oprea TI, Dun NJ: Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia. J Neurosci Res 2009; 87: 1610-1619
38. Simerly RB, Carr AM, Zee MC, Lorang D: Ovarian steroid regulation of estrogen and progesterone receptor messenger ribonucleic acid in the anteroventral periventricular nucleus of the rat. J Neuroendocrinol 1996; 8: 45-56
39. Filardo E, Quinn J, Pang Y, Graeber C, Shaw S, Dong J, Thomas P: Activation of the novel estrogen receptor G protein-coupled receptor (GPR30) at the plasma membrane. Endocrinology 2007; 148: 3236-3245
40. Goldman RK, Azar AS, Mulvaney JM, Brooks VL: Baroreflex sensitivity varies during the estrus cycle of the rat. FASEB J 2008; 22: 941.12
41. Saleh TM, Connell BJ: Role of oestrogen in the central regulation of autonomic function. Clin Exp Pharmacol Physiol 2007; 34: 827-832
42. Otto C, Fuchs I, Kauselmann G, Kern H, Zevnik B, Andreasen P, Schwarz G, Altmann H, Klewer M, Schoor M, Vonk R, Fritzemeier KH: GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biol Reprod 2009; 80: 34-41
43. Cornil CA, Charlier TD: Rapid behavioural effects of oestrogens and fast regulation of their local synthesis by brain aromatase. J Neuroendocrinol 2010; 22: 664-673
44. Sanghera MK, Simpson ER, McPhaul MJ, Kozlowski G, Conley AJ, Lephart ED: Immunocytochemical distribution of aromatase cytochrome P450 in the rat brain using peptide-generated polyclonal antibodies. Endocrinology 1991; 129: 2834-2844
45. Evrard HC, Harada N, Balthazart J: Immunocytochemical localization of aromatase in sensory and integrating nuclei of the hindbrain in Japanese quail (Coturnix japonica). J Comp Neurol 2004; 473: 194-212
46. Hermann DM, Luppi PH, Peyron C, Hinckel P, Jouvet M: Afferent projections to the rat nuclei raphe magnus, raphe pallidus and reticularis gigantocellularis pars alpha demonstrated by iontophoretic application of choleratoxin (subunit b). J Chem Neuroanat 1997; 13: 1-21
47. Morrison SF, Nakamura K, Madden CJ: Central control of thermogenesis in mammals. Exp Physiol 2008; 93: 773-797
48. Heinricher MM, Tavares I, Leith JL, Lumb BM: Descending control of nociception: Specificity, recruitment and plasticity. Brain Res Rev 2009; 60: 214-225
49. Kenney MJ, Weiss ML, Haywood JR: The paraventricular nucleus: An important component of the central neurocircuitry regulating sympathetic nerve outflow. Acta Physiol Scand 2003; 177: 7-15
50. Dean C: Sympathoinhibition from ventrolateral periaqueductal gray mediated by the caudal midline medulla. Am J Physiol Regul Integr Comp Physiol 2005; 289:R1477-R1481
51. Krout KE, Loewy AD: Periaqueductal gray matter projections to midline and intralaminar thalamic nuclei of the rat. J Comp Neurol 2000; 424: 111-141
52. Curtis KS: Estrogen and the central control of body fluid balance. Physiol Behav 2009; 97: 180-192
53. Filardo EJ, Thomas P: GPR30: A seven-transmembrane-spanning estrogen receptor that triggers EGF release. Trends Endocrinol Metab 2005; 16: 362-367.