Acute injection of 17β-estradiol enhances cardiovascular reflexes and autonomic tone in ovariectomized female rats

Autonomic Neuroscience: Basic and Clinical

Volumn 84, Issue 1-2, 2000, Pages 78-88

  Saleh, Tarek M ^a   Connell, Barry J ^a   Saleh, Monique C ^a  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

ICI 182,780; Parasympathetic tone; Renal nerve; Sympathetic tone; Vagus nerve

Indexed keywords

7ALPHA [9 (4,4,5,5,5 PENTAFLUOROPENTYLSULFINYL)NONYL]ESTRA 1,3,5(10) TRIENE 3,17BETA DIOL; ESTRADIOL; ESTROGEN RECEPTOR; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; CARDIOTONIC AGENT; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CARDIOVASCULAR REFLEX; CONTROLLED STUDY; DOSE RESPONSE; ESTROGEN ACTIVITY; ESTROGEN THERAPY; FEMALE; HEART RATE; HEMODYNAMICS; NONHUMAN; OVARIECTOMY; PARASYMPATHETIC NERVE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE; ADRENERGIC NERVE; ANIMAL; BLOOD PRESSURE; DRUG EFFECT; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VAGUS NERVE;

ADRENERGIC FIBERS; ANIMALS; BAROREFLEX; BLOOD PRESSURE; CARDIOTONIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; FEMALE; HEART RATE; NITROPRUSSIDE; OVARIECTOMY; PARASYMPATHETIC FIBERS, POSTGANGLIONIC; PHENYLEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; VAGUS NERVE; VASODILATOR AGENTS;

EID: 0034735309     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1566-0702(00)00196-X     Document Type: Article

References (38)

1. Amandusson A., Hermanson O., Blomqvist A. Estrogen receptor-like immunoreactivity in the medullary and spinal dorsal horn of the female rat. Neurosci. Lett. 196:1995;25-28.
2. Barron H.V., Lesh M.D. Autonomic nervous system and sudden cardiac death. J. Am. Coll. Cardiol. 27:1996;1053-1060.
3. Becker R.C., Carrero J.M. Cardiovascular disease in women. Cardiology. 77:1990;1-140.
4. Blaustein J.D. Estrogen receptor immunoreactivity in rat brain: rapid effects of estradiol injection. Endocrinology. 132:1993;1218-1224.
5. Bolego C., Cignarella A., Ruzza R., Zanisi M., Puglisi L. Differential effects of low and high dose estrogen treatments on vascular responses in female rats. Life Sci. 60:1997;2291-2302.
6. Casolo G.C., Stroder P., Signorini C. Heart rate variability during the acute phase of myocardial infarction. Circulation. 85:1992;2073-2079.
7. Collins P., Shay J., Jiang C., Moss J. Nitric oxide accounts for dose-dependent estrogen-mediated coronary relaxation after acute estrogen withdrawal. Circulation. 90:1994;1964-1968.
8. Collins P., Rosano G.M.C., Sarrel P.M., Ulrich L., Adamopoulus S., Poole-Wilson P.A. 17β-Estradiol attenuates acetylcholine-induced coronary vasoconstriction in women but not in men with coronary artery disease. Circulation. 92:1995;24-30.
9. De Ferrari G.M., Vanoli V.M., Cerati D., Scwartz P.J. Baroreceptor reflexes and sudden cardiac death: experimental findings and background. G. Ital. Cardiol. 22:1992;629-637.
10. Del Rio G., Velardo A., Menozzi R., Zizzo G., Tavernari V., Venneri M.G., Marrama P., Petraglia F. Acute estradiol and progesterone administration reduced cardiovascular and catecholamine responses to mental stress in menopausal women. Neuroendocrinology. 67:1998;269-274.
11. Gillian D.M., Badar D.M., Panza J.A., Quyyumi A.A., Cannon R.O. Acute vascular effects of estrogen in postmenopausal women. Circulation. 90:1994;786-791.
12. Hyder S.M., Chiappetta C., Murthy L., Stancel G.M. Selective inhibition of estrogen-regulated gene expression in vivo by the pure antiestrogen ICI 182, 780. Cancer Res. 57:1997;2547-2549.
13. Kannel W.B., Wilson P., Agostino R., Cobb J. Sudden coronary death in women. Am. Heart J. 136:1998;205-212.
14. Kondo K., Okuno T., Eguchi T., Yasui T., Suzuki H., Nagahama S., Saruta T. Vascular actions of high dose estrogen in rats. Endocrinol. Jpn. 27:1980;307-313.
15. Laflamme N., Nappi R.E., Drolet G., Labrie C., Rivest S. Expression and neuropeptidergic characterization of estrogen receptors (ERα and ERβ) throughout the rat brain: anatomical evidence of distinct roles of each subtype. J. Neurobiol. 36:1998;357-378.
16. Laitinen T., Hartikainen J., Niskanen L., Geelen G., Lansimies E. Sympathovagal balance is major determinant of short-term blood pressure variability in health subjects. Am. J. Physiol. 276:1999;H1245-H1252.
17. Myerburg R.J., Cox M.M., Interian A., Mitrani R., Girgis I., Dylewski J., Castellanos A. Cycling of inducibility of paroxysmal supraventricular tachycardia in women and its implications for timing of electrophysiological procedures. Am. J. Cardiol. 83:1999;1049-1054.
18. Notelovitz M. Clinical experience with a 7-day estrogen patch: principles and practice. Gynecol. Endocrinol. 12:1998;249-258.
19. Ottenson B., Sørensen M.B. Women at cardiac risk: is HRT the route to maintaining cardiovascular health? Int. J. Gynecol. Obstet. 59:1997;S19-S27.
20. Pines A., Averbuch M., Fisman E.Z., Rosano G.M.C. The acute effects of sublingual 17-estradiol on the cardiovascular system. Maturitas. 33:1999;81-85.
21. Saleh T.M., Connell B.J. The role of 17β-estradiol in the modulation of baroreflex sensitivity in male rats. Am. J. Physiol. 275:1998;R770-R778.
22. Saleh T.M., Connell B.J. Centrally mediated effect of 17β-estradiol on parasympathetic tone in male rats. Am. J. Physiol. 276:1999;R474-R481.
23. Saleh T.M., Connell B.J. 17β-Estradiol modulates baroreflex sensitivity and autonomic tone of female rats. J. Autonom. Nerv. Sys. 80:2000;148-161.
24. Shughrue P.J., Bushnell C.D., Dorsa D.M. Estrogen receptor mRNA in female rat brain during estrous cycle: A comparison with ovariectomized female and intact males. Endocrinology. 131:1992;381-388.
25. Shughrue P.J., Lane M.V., Merchenthaler I. Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system. J. Comp. Neurol. 388:1997;507-525.
26. Simerly R.B., Chang C., Murammatsu M., Swanson L.W. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J. Comp. Neurol. 294:1990;76-95.
27. Sleight P. The importance of the autonomic nervous system in health and disease. Aust. NZ. J. Med. 27:1997;467-473.
28. Smith M.S., Freeman M.E., Neill J.D. The control of progesterone secretion during estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy. Endocrinology. 96:1975;219-230.
29. Sohrabji F., Miranda R.C., Toran-Allerand C.D. Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons. J. Neurosci. 14:1994;459-471.
30. Sourander L., Rajala T., Helenius H. Cardiovascular and cancer morbidity and mortality and sudden cardiac death in postmenopausal women on ERT. Lancet. 352:1998;1965-1969.
31. Sullivan J.M. Is too much estrogen bad for the heart. Menopause. 5:1998;77-78.
32. Turner A.W.M., Malik M. Risk stratification and prediction of sudden death following myocardial infarction. Herz. 20:1995;200-212.
33. Vaccarino V., Parsons L., Every N.R., Barron H.V., Krumholz H.M. Sex-based differences in early mortality after myocardial infarction. New Engl. J. Med. 341:1999;217-225.
34. Wakeling A.E., Dukes M., Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res. 51:1991;3867-3873.
35. Weeth J.B., Segalov A. Massive estrogen therapy: Phase I study of hexestrol. Cancer Chemother. Rep. 48:1965;53-56.
36. Williams J.K., Adams M.R., Kloppenstein H.S. Estrogen modulates responses of athersclerotic coronary artery. Circulation. 81:1990;1680-1687.
37. Wooley C.S. Electrophysiologiacl and cellular effects of estrogen on neuronal function. Crit. Rev. Neurobiol. 13:1999;1-20.
38. Yikorkala O., Cacciatore B., Paakkari I., Tikkanen M., Vinikka L., Toivonen J. The long-term effects of oral and transdermal postmenopausal hormone replacement therapy on nitric oxide, endothelin-1, prostacyclin, and thromboxane. Fertil. Steril. 69:1998;883-888.