메뉴 건너뛰기




Volumn 328, Issue 1-2, 2013, Pages 19-23

The deletion variant of α2b-adrenergic receptor is associated with decreased risk in Alzheimer's disease and mild cognitive impairment

Author keywords

ADRA2B polymorphisms; Alzheimer's disease; APOE polymorphisms; Emotional memory

Indexed keywords

ALPHA 2B ADRENERGIC RECEPTOR; APOLIPOPROTEIN E; GENOMIC DNA;

EID: 84876143103     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2013.02.003     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 79952574501 scopus 로고    scopus 로고
    • Epidemiology of Alzheimer disease
    • C. Reitz, C. Brayne, and R. Mayeux Epidemiology of Alzheimer disease Nat Rev Neurol 7 2011 137 152
    • (2011) Nat Rev Neurol , vol.7 , pp. 137-152
    • Reitz, C.1    Brayne, C.2    Mayeux, R.3
  • 2
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • J. Hardy, and G.A. Higgins Alzheimer's disease: the amyloid cascade hypothesis Science 256 1992 184 185
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.1    Higgins, G.A.2
  • 4
    • 77953388335 scopus 로고    scopus 로고
    • Genetics of Alzheimer disease in the pre- and post-GWAS era
    • N. Ertekin-Taner Genetics of Alzheimer disease in the pre- and post-GWAS era Alzheimers Res Ther 2 2010 3
    • (2010) Alzheimers Res Ther , vol.2 , pp. 3
    • Ertekin-Taner, N.1
  • 5
    • 84887017521 scopus 로고    scopus 로고
    • http://www.alzforum.org/res/com/gen/alzgene/default.asp
  • 6
    • 0019872434 scopus 로고
    • Selective loss of neurons of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia
    • W. Bondareff, C.Q. Mountjoy, and M. Roth Selective loss of neurons of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia Lancet 1 1981 783 784
    • (1981) Lancet , vol.1 , pp. 783-784
    • Bondareff, W.1    Mountjoy, C.Q.2    Roth, M.3
  • 7
    • 0022636640 scopus 로고
    • Loss of nerve cells from locus coeruleus in Alzheimer's disease is topographically arranged
    • DOI 10.1016/0304-3940(86)90336-8
    • B. Marcyniuk, D.M. Mann, and P.O. Yates Loss of nerve cells from locus coeruleus in Alzheimer's disease is topographically arranged Neurosci Lett 64 1986 247 252 (Pubitemid 16163819)
    • (1986) Neuroscience Letters , vol.64 , Issue.3 , pp. 247-252
    • Marcyniuk, B.1    Mann, D.M.A.2    Yates, P.O.3
  • 8
    • 0024431682 scopus 로고
    • Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer type and Parkinson's disease with and without dementia and depression
    • V. Chan-Palay, and E. Asan Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer's type and in Parkinson's disease with and without dementia and depression J Comp Neurol 287 1989 373 392 (Pubitemid 19239069)
    • (1989) Journal of Comparative Neurology , vol.287 , Issue.3 , pp. 373-392
    • Chan-Palay, V.1    Asan, E.2
  • 10
    • 0037337815 scopus 로고    scopus 로고
    • Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
    • DOI 10.1001/archneur.60.3.337
    • C. Zarow, S.A. Lyness, J.A. Mortimer, and H.C. Chui Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer's and Parkinson's disease Arch Neurol 60 2003 337 341 (Pubitemid 36314358)
    • (2003) Archives of Neurology , vol.60 , Issue.3 , pp. 337-341
    • Zarow, C.1    Lyness, S.A.2    Mortimer, J.A.3    Chui, H.C.4
  • 11
    • 32544460565 scopus 로고    scopus 로고
    • Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with lewy bodies
    • DOI 10.1523/JNEUROSCI.4265-05.2006
    • P. Szot, S.S. White, J.L. Greenup, J.B. Leverenz, E.R. Peskind, and M.A. Raskind Compensatory changes in the noradrenergic nervous system in the locus coeruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy Bodies J Neurosci 26 2006 467 478 (Pubitemid 43237111)
    • (2006) Journal of Neuroscience , vol.26 , Issue.2 , pp. 467-478
    • Szot, P.1    White, S.S.2    Lynne Greenup, J.3    Leverenz, J.B.4    Peskind, E.R.5    Raskind, M.A.6
  • 12
    • 79151475168 scopus 로고    scopus 로고
    • Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease
    • P.J. McMillan, S.S. White, A. Franklin, J.L. Greenup, J.B. Leverenz, and M.A. Raskind Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease Brain Res 1373 2011 240 252
    • (2011) Brain Res , vol.1373 , pp. 240-252
    • McMillan, P.J.1    White, S.S.2    Franklin, A.3    Greenup, J.L.4    Leverenz, J.B.5    Raskind, M.A.6
  • 13
    • 0036669380 scopus 로고    scopus 로고
    • Role of adrenoceptor subtypes in memory consolidation
    • DOI 10.1016/S0301-0082(02)00023-0, PII S0301008202000230
    • M.E. Gibbs, and R.J. Summers Role of adrenoceptor subtypes in memory consolidation Prog Neurobiol 67 2002 345 391 (Pubitemid 35257911)
    • (2002) Progress in Neurobiology , vol.67 , Issue.5 , pp. 345-391
    • Gibbs, M.E.1    Summers, R.J.2
  • 14
    • 0033765025 scopus 로고    scopus 로고
    • Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders
    • K.J. Ressler, and C.B. Nemeroff Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders Depress Anxiety 12 Suppl. 1 2000 2 19
    • (2000) Depress Anxiety , vol.12 , Issue.SUPPL. 1 , pp. 2-19
    • Ressler, K.J.1    Nemeroff, C.B.2
  • 15
    • 0018707462 scopus 로고
    • Regional topography within noradrenergic locus coeruleus as revealed by retrograde transport of horseradish peroxidase
    • DOI 10.1002/cne.901870405
    • S.T. Mason, and H.C. Fibiger Regional topography within noradrenergic locus coeruleus as revealed by retrograde transport of horseradish peroxidase J Comp Neurol 187 1979 703 724 (Pubitemid 10227020)
    • (1979) Journal of Comparative Neurology , vol.187 , Issue.4 , pp. 703-724
    • Mason, S.T.1    Fibiger, H.C.2
  • 17
    • 0022534005 scopus 로고
    • Efferent projections of nucleus locus coeruleus: Morphologic subpopulations have different efferent targets
    • DOI 10.1016/0306-4522(86)90156-9
    • S.E. Loughlin, S.L. Foote, and R. Grzanna Efferent projections of nucleus locus coeruleus: morphologic sub-populations have different efferent's targets Neuroscience 18 1986 307 319 (Pubitemid 16065456)
    • (1986) Neuroscience , vol.18 , Issue.2 , pp. 307-319
    • Loughlin, S.E.1    Foote, S.L.2    Grzanna, R.3
  • 18
    • 81555214518 scopus 로고    scopus 로고
    • A comparative study of five mouse models of Alzheimer's disease: Cell cycle events reveal new insights into neurons at risk for death
    • L. Li, T. Cheung, J. Chen, and K. Herrup A comparative study of five mouse models of Alzheimer's disease: cell cycle events reveal new insights into neurons at risk for death Int J Alzheimers Dis 2011 2011 1714 1764
    • (2011) Int J Alzheimers Dis , vol.2011 , pp. 1714-1764
    • Li, L.1    Cheung, T.2    Chen, J.3    Herrup, K.4
  • 19
    • 3042572690 scopus 로고    scopus 로고
    • Structural determinants involved in the activation and regulation of G protein-coupled receptors: Lessons from the alpha1-adrenegic receptor subtypes
    • DOI 10.1016/j.biolcel.2004.03.009, PII S024849000400084X
    • S. Cotecchia, L. Stanasila, D. Diviani, K. Björklöf, O. Rossier, and F. Fanelli Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the α1-adrenegic receptor subtypes Biol Cell 96 2004 327 333 (Pubitemid 38807897)
    • (2004) Biology of the Cell , vol.96 , Issue.5 , pp. 327-333
    • Cotecchia, S.1    Stanasila, L.2    Diviani, D.3    Bjorklof, K.4    Rossier, O.5    Fanelli, F.6
  • 20
    • 0034892738 scopus 로고    scopus 로고
    • 2-adrenoceptors
    • DOI 10.1046/j.1471-4159.2001.00484.x
    • K. Starke Presynaptic autoreceptors in the third decade: focus on α2-adrenoceptors J Neurochem 78 2001 685 693 (Pubitemid 32777970)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.4 , pp. 685-693
    • Starke, K.1
  • 21
    • 82955173741 scopus 로고    scopus 로고
    • 2-heteroreceptors and autoreceptors respectively?
    • 2- heteroreceptors and autoreceptors respectively? Br J Pharmacol 165 2012 90 102
    • (2012) Br J Pharmacol , vol.165 , pp. 90-102
    • Gilsbach, R.1    Hein, L.2
  • 22
    • 0033547241 scopus 로고    scopus 로고
    • Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
    • L. Hein, J.D. Altman, and B.K. Kobilka Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission Nature 402 1999 181 184
    • (1999) Nature , vol.402 , pp. 181-184
    • Hein, L.1    Altman, J.D.2    Kobilka, B.K.3
  • 23
    • 1442288386 scopus 로고    scopus 로고
    • 2B Adrenoceptor Gene, a Positional Candidate on Chromosome 2, Associates with Hypertension
    • DOI 10.1161/01.HYP.0000116224.51189.80
    • F. Von Wowern, K. Bengtsson, U. Lindblad, L. Råstam, and O. Melander Functional variant in the 2B adrenoceptor gene, a positional candidate on chromosome 2, associates with hypertension Hypertension 43 2004 592 597 (Pubitemid 38282433)
    • (2004) Hypertension , vol.43 , Issue.3 , pp. 592-597
    • Von Wowern, F.1    Bengtsson, K.2    Lindblad, U.3    Rastam, L.4    Melander, O.5
  • 25
    • 0026552577 scopus 로고
    • Review article: Adrenergic control of motor and secretory function in the gastrointestinal tract
    • A.S. McIntyre, and D.G. Thompson Review article: adrenergic control of motor and secretory function in the gastrointestinal tract Aliment Pharmacol Ther 6 1992 125 142
    • (1992) Aliment Pharmacol Ther , vol.6 , pp. 125-142
    • McIntyre, A.S.1    Thompson, D.G.2
  • 26
    • 33745967215 scopus 로고    scopus 로고
    • 2A- adrenergic receptor
    • DOI 10.1182/blood-2005-12-4835
    • M. Pozgajová, U.J. Sachs, L. Hein, and B. Nieswandt Reduced thrombus stability in mice lacking the α2A-adrenergic receptor Blood 108 2006 510 514 (Pubitemid 44061349)
    • (2006) Blood , vol.108 , Issue.2 , pp. 510-514
    • Pozgajova, M.1    Sachs, U.J.H.2    Hein, L.3    Nieswandt, B.4
  • 27
    • 0029945067 scopus 로고    scopus 로고
    • Role of catecholamines in platelet function: Pathophysiological and clinical significance
    • G. Anfossi, and M. Trovati Role of catecholamines in platelet function: pathophysiological and clinical significance Eur J Clin Invest 26 1996 353 370 (Pubitemid 26171949)
    • (1996) European Journal of Clinical Investigation , vol.26 , Issue.5 , pp. 353-370
    • Anfossi, G.1    Trovati, M.2
  • 28
    • 0035895936 scopus 로고    scopus 로고
    • Polymorphic deletion of three intracellular acidic residues of the α 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization
    • K.M. Small, K.M. Brown, S.L. Forbes, and S.B. Liggett Polymorphic deletion of three intracellular acidic residues of the α 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization J Biol Chem 276 2001 4917 4922
    • (2001) J Biol Chem , vol.276 , pp. 4917-4922
    • Small, K.M.1    Brown, K.M.2    Forbes, S.L.3    Liggett, S.B.4
  • 29
    • 0032836393 scopus 로고    scopus 로고
    • Stimulation of the noradrenergic system enhances and blockade reduces memory for emotional material in man
    • DOI 10.1017/S0033291799008703
    • R.E. O'Carroll, E. Drysdale, L. Cahill, P. Shajahan, and K.P. Ebmeier Stimulation of the noradrenergic system enhances and blockade reduces memory for emotional material in man Psychol Med 29 1999 1083 1088 (Pubitemid 29469298)
    • (1999) Psychological Medicine , vol.29 , Issue.5 , pp. 1083-1088
    • O'Carroll, R.E.1    Drysdale, E.2    Cahill, L.3    Shajahan, P.4    Ebmeier, K.P.5
  • 31
    • 73149117555 scopus 로고    scopus 로고
    • A genetic variation of the noradrenergic system is related to differential amygdala activation during encoding of emotional memories
    • B. Rasch, K. Spalek, S. Buholzer, R. Luechinger, P. Boesiger, and A. Papassotiropoulos A genetic variation of the noradrenergic system is related to differential amygdala activation during encoding of emotional memories Proc Natl Acad Sci U S A 106 2009 19191 19196
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19191-19196
    • Rasch, B.1    Spalek, K.2    Buholzer, S.3    Luechinger, R.4    Boesiger, P.5    Papassotiropoulos, A.6
  • 32
    • 77349123977 scopus 로고    scopus 로고
    • Deletion variant of α2b-adrenergic receptor gene moderates the effect of COMT val(158)met polymorphism on episodic memory performance
    • A.A. Gibbs, K.H. Naudts, R.T. Azevedo, and A.S. David Deletion variant of α2b-adrenergic receptor gene moderates the effect of COMT val(158)met polymorphism on episodic memory performance Eur Neuropsychopharmacol 20 2010 272
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 272
    • Gibbs, A.A.1    Naudts, K.H.2    Azevedo, R.T.3    David, A.S.4
  • 34
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price, and E.M. Stadlan Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease Neurology 34 1984 939 944 (Pubitemid 14076461)
    • (1984) Neurology , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 36
    • 0030870822 scopus 로고    scopus 로고
    • Improved method for genotyping apolipoprotein e polymorphisms by a PCR-based assay simultaneously utilizing two distinct restriction enzymes
    • A. Zivelin, N. Rosenberg, H. Peretz, Y. Amit, N. Kornbrot, and U. Seligsohn Improved method for genotyping apolipoprotein E polymorphisms by a PCR-based assay simultaneously utilizing two distinct restriction enzymes Clin Chem 43 1997 1657 1659
    • (1997) Clin Chem , vol.43 , pp. 1657-1659
    • Zivelin, A.1    Rosenberg, N.2    Peretz, H.3    Amit, Y.4    Kornbrot, N.5    Seligsohn, U.6
  • 37
    • 0037724276 scopus 로고    scopus 로고
    • Involvement of β-adrenergic receptors in protein synthesis-dependent late long-term potentiation (LTP) in the dentate gyrus of freely moving rats: The critical role of the LTP induction strength
    • DOI 10.1016/S0306-4522(03)00151-9
    • T. Straube, and J.U. Frey Involvement of [β]-adrenergic receptors in protein synthesis-dependent late long-term potentiation (LTP) in the dentate gyrus of freely moving rats: the critical role of the LTP induction strength Neuroscience 119 2003 473 479 (Pubitemid 36588825)
    • (2003) Neuroscience , vol.119 , Issue.2 , pp. 473-479
    • Straube, T.1    Frey, J.U.2
  • 38
    • 0036501401 scopus 로고    scopus 로고
    • Noradrenergic changes, aggressive behavior, and cognition in patients with dementia
    • DOI 10.1016/S0006-3223(01)01235-5, PII S0006322301012355
    • K.L. Matthews, C.P. Chen, M.M. Esiri, J. Keene, S.L. Minger, and P.T. Francis Noradrenergic changes, aggressive behavior, and cognition in patients with dementia Biol Psychiatry 51 2002 407 416 (Pubitemid 34251178)
    • (2002) Biological Psychiatry , vol.51 , Issue.5 , pp. 407-416
    • Matthews, K.L.1    Chen, C.P.L.-H.2    Esiri, M.M.3    Keene, J.4    Minger, S.L.5    Francis, P.T.6
  • 39
    • 78651072485 scopus 로고    scopus 로고
    • CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease
    • A. Caccamo, M.A. Maldonado, A.F. Bokov, S. Majumder, and S. Oddo CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease Proc Natl Acad Sci U S A 107 2010 22687 22692
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 22687-22692
    • Caccamo, A.1    Maldonado, M.A.2    Bokov, A.F.3    Majumder, S.4    Oddo, S.5
  • 40
    • 0036792096 scopus 로고    scopus 로고
    • Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
    • O.V. Vitolo, A. Sant'Angelo, V. Costanzo, F. Battaglia, O. Arancio, and M. Shelanski Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling Proc Natl Acad Sci U S A 99 2002 13217 13221
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13217-13221
    • Vitolo, O.V.1    Sant'Angelo, A.2    Costanzo, V.3    Battaglia, F.4    Arancio, O.5    Shelanski, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.