Ovarian malignant ascites-derived lymphocytes stimulated with prothymosin α or its immunoactive decapeptide lyse autologous tumour cells in vitro and retard tumour growth in SCID mice

European Journal of Cancer

Volumn 49, Issue 7, 2013, Pages 1706-1714

  Voutsas, Ioannis F ^a   Pistamaltzian, Nikolaos ^b   Tsiatas, Marinos L ^a,b   Skopeliti, Margarita ^a   Katsila, Theodora ^a   Mavrothalassiti, Ilektra ^a   Spyrou, Spyros ^c   Dimopoulos, Meletios Athanassios ^b   Tsitsilonis, Ourania E ^a   Bamias, Aristotelis ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c NONE   (Greece)

Author keywords

Ascites; Human tumour xenografts; Ovarian cancer; Prothymosin alpha; SCID mice; T cell activation; Tumour associated lymphocytes

Indexed keywords

ANTINEOPLASTIC AGENT; IMMUNOSTIMULATING AGENT; LYSINE; PROTHYMOSIN ALPHA; PROTHYMOSIN ALPHA(100-109); UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CANCER PATIENT; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; MALIGNANT ASCITES; MOLECULE; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; SCID MOUSE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL; TUMOR GROWTH; TUMOR VOLUME;

ADULT; AGED; ANIMALS; ASCITES; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; HUMANS; IMMUNOTHERAPY, ADOPTIVE; K562 CELLS; KAPLAN-MEIER ESTIMATE; LYMPHOCYTE ACTIVATION; LYMPHOCYTES, TUMOR-INFILTRATING; MICE; MICE, SCID; MIDDLE AGED; OLIGOPEPTIDES; OVARIAN NEOPLASMS; PROTEIN PRECURSORS; THYMOSIN; TUMOR BURDEN; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84876125597     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.11.037     Document Type: Article

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