-
1
-
-
78649339242
-
An introduction to the molecular basics of aryl hydrocarbon receptor biology
-
Abel, J., and Haarmann-Stemmann, T. (2010). An introduction to the molecular basics of aryl hydrocarbon receptor biology. Biol. Chem. 391,1235-1248.
-
(2010)
Biol. Chem.
, vol.391
, pp. 1235-1248
-
-
Abel, J.1
Haarmann-Stemmann, T.2
-
2
-
-
77955293411
-
The effects of cytochrome P450 induction by xenobiotics on endobiotic metabolism in pre-clinical safety studies
-
Amacher, D. E. (2010). The effects of cytochrome P450 induction by xenobiotics on endobiotic metabolism in pre-clinical safety studies. Toxicol. Mech. Methods 20, 159-166.
-
(2010)
Toxicol. Mech. Methods
, vol.20
, pp. 159-166
-
-
Amacher, D.E.1
-
3
-
-
78649889331
-
Radioligand binding characterization of [3H]-A-998679, a novel positive allosteric modulator of α4β2 nAChRs
-
Anderson, D. J., Vaidyanathan, S., Namovic, M., Donnelly-Roberts, D., Lee, L., and Gopalakrishnan, M. (2009). Radioligand binding characterization of [3H]-A-998679, a novel positive allosteric modulator of α4β2 nAChRs. Biochem. Pharmacol. 78, 903-904.
-
(2009)
Biochem. Pharmacol.
, vol.78
, pp. 903-904
-
-
Anderson, D.J.1
Vaidyanathan, S.2
Namovic, M.3
Donnelly-Roberts, D.4
Lee, L.5
Gopalakrishnan, M.6
-
4
-
-
34447511096
-
The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein
-
Barouki, R., Coumoul, X., and Fernandez-Salguero, P. M. (2007). The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein. FEBS Lett. 581, 3608-3615.
-
(2007)
FEBS Lett
, vol.581
, pp. 3608-3615
-
-
Barouki, R.1
Coumoul, X.2
Fernandez-Salguero, P.M.3
-
5
-
-
0035282835
-
Repression of cytochrome P450 1A1 gene expression by oxidative stress: mechanisms and biological implications
-
Barouki, R., and Morel, Y. (2001). Repression of cytochrome P450 1A1 gene expression by oxidative stress: mechanisms and biological implications. Biochem. Pharmacol. 61,511-516.
-
(2001)
Biochem. Pharmacol.
, vol.61
, pp. 511-516
-
-
Barouki, R.1
Morel, Y.2
-
6
-
-
61349086670
-
Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development
-
Blomme, E. A., Yang, Y., and Waring, J. F. (2009). Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development. Toxicol. Lett. 186,22-31.
-
(2009)
Toxicol. Lett.
, vol.186
, pp. 22-31
-
-
Blomme, E.A.1
Yang, Y.2
Waring, J.F.3
-
7
-
-
0027406654
-
Fluvoxamine is a potent inhibitor of cytochrome P4501A2
-
Brosen, K., Skjelbo, E., Rasmussen, B. B., Poulsen, H. E., and Loft, S. (1993). Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochem. Pharmacol. 45,1211-1214.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1211-1214
-
-
Brosen, K.1
Skjelbo, E.2
Rasmussen, B.B.3
Poulsen, H.E.4
Loft, S.5
-
8
-
-
13844322067
-
Cytochrome P450, nature's most versatile biological catalyst
-
Coon, M. J. (2005). Cytochrome P450, nature's most versatile biological catalyst. Annu. Rev. Pharmacol. Toxicol. 45, 1-25.
-
(2005)
Annu. Rev. Pharmacol. Toxicol.
, vol.45
, pp. 1-25
-
-
Coon, M.J.1
-
9
-
-
0026482775
-
Omeprazole, an inducer of human CYP1A1 and 1A2, is not a ligand for the Ah receptor
-
Daujat, M., Peryt, B., Lesca, P., Fourtanier, G., Domergue, J., and Maurel, P. (1992). Omeprazole, an inducer of human CYP1A1 and 1A2, is not a ligand for the Ah receptor. Biochem. Biophys. Res. Commun. 188, 820-825.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.188
, pp. 820-825
-
-
Daujat, M.1
Peryt, B.2
Lesca, P.3
Fourtanier, G.4
Domergue, J.5
Maurel, P.6
-
10
-
-
84155196846
-
Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor
-
Denison, M. S., Soshilov, A. A., He, G., Degroot, D. E., and Zhao, B. (2011). Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicol. Sci. 124, 1-22.
-
(2011)
Toxicol. Sci.
, vol.124
, pp. 1-22
-
-
Denison, M.S.1
Soshilov, A.A.2
He, G.3
Degroot, D.E.4
Zhao, B.5
-
11
-
-
0025368026
-
Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450
-
Diaz, D., Fabre, I., Daujat, M., Saint Aubert, B., Bories, P., Michel, H., et al. (1990). Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450. Gastroenterology 99, 737-747.
-
(1990)
Gastroenterology
, vol.99
, pp. 737-747
-
-
Diaz, D.1
Fabre, I.2
Daujat, M.3
Saint Aubert, B.4
Bories, P.5
Michel, H.6
-
12
-
-
0020929522
-
Preparation of primary cultures of rat hepatocytes suitable for in vitro toxicity testing
-
Elliget, K. A., and Kolaja, G. J. (1983). Preparation of primary cultures of rat hepatocytes suitable for in vitro toxicity testing. Methods Cell Sci. 8, 1-6.
-
(1983)
Methods Cell Sci
, vol.8
, pp. 1-6
-
-
Elliget, K.A.1
Kolaja, G.J.2
-
13
-
-
10044260714
-
Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2-mediated presystemic metabolism
-
Granfors, M. T., Backman, J. T., Neuvonen, M., and Neuvonen, P. J. (2004). Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2-mediated presystemic metabolism. Clin. Pharmacol. Ther. 76, 598-606.
-
(2004)
Clin. Pharmacol. Ther.
, vol.76
, pp. 598-606
-
-
Granfors, M.T.1
Backman, J.T.2
Neuvonen, M.3
Neuvonen, P.J.4
-
14
-
-
35648976075
-
Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations
-
Hewitt, N. J., Lecluyse, E. L., and Ferguson, S. S. (2007). Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations. Xenobiotica 37, 1196-1224.
-
(2007)
Xenobiotica
, vol.37
, pp. 1196-1224
-
-
Hewitt, N.J.1
Lecluyse, E.L.2
Ferguson, S.S.3
-
15
-
-
34347327220
-
Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro
-
Hu, W., Sorrentino, C., Denison, M. S., Kolaja, K., and Fielden, M. R. (2007). Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. Mol. Pharmacol. 71, 1475-1486.
-
(2007)
Mol. Pharmacol.
, vol.71
, pp. 1475-1486
-
-
Hu, W.1
Sorrentino, C.2
Denison, M.S.3
Kolaja, K.4
Fielden, M.R.5
-
16
-
-
30944464238
-
Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand
-
Jinno, A., Maruyama, Y., Ishizuka, M., Kazusaka, A., Nakamura, A., and Fujita, S. (2006). Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand. J. Steroid Biochem. Mol. Biol. 98,48-55.
-
(2006)
J. Steroid Biochem. Mol. Biol.
, vol.98
, pp. 48-55
-
-
Jinno, A.1
Maruyama, Y.2
Ishizuka, M.3
Kazusaka, A.4
Nakamura, A.5
Fujita, S.6
-
17
-
-
44149110127
-
Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z)-5-[(1, 2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2, 4-dimethyl-1H-pyrro le-3-propanoic acid (TSU-68)
-
Kitamura, R., Asanoma, H., Nagayama, S., and Otagiri, M. (2008). Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z)-5-[(1, 2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2, 4-dimethyl-1H-pyrro le-3-propanoic acid (TSU-68). DrugMetab. Dispos. 36, 1003-1009.
-
(2008)
DrugMetab. Dispos.
, vol.36
, pp. 1003-1009
-
-
Kitamura, R.1
Asanoma, H.2
Nagayama, S.3
Otagiri, M.4
-
18
-
-
34548093853
-
Decrease in plasma concentrations of antiangio-genic agent TSU-68 ((Z)-5-[(1, 2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2, 4-dimethyl-1H-pyrr ole-3-propanoic acid) during oral administration twice a day to rats
-
Kitamura, R., Yamamoto, Y., Nagayama, S., and Otagiri, M. (2007). Decrease in plasma concentrations of antiangio-genic agent TSU-68 ((Z)-5-[(1, 2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2, 4-dimethyl-1H-pyrr ole-3-propanoic acid) during oral administration twice a day to rats. DrugMetab. Dispos. 35, 1611-1616.
-
(2007)
DrugMetab. Dispos.
, vol.35
, pp. 1611-1616
-
-
Kitamura, R.1
Yamamoto, Y.2
Nagayama, S.3
Otagiri, M.4
-
19
-
-
77956920406
-
Cytochrome P4501A1 is required for vascular dysfunction and hypertension induced by 2 3 7, 8-tetrachlorodibenzo-p-dioxin
-
Kopf, P. G., Scott, J. A., Agbor, L. N., Boberg, J. R., Elased, K. M., Huwe, J. K., et al. (2010). Cytochrome P4501A1 is required for vascular dysfunction and hypertension induced by 2 3 7, 8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 117,537-546.
-
(2010)
Toxicol. Sci
, vol.117
, pp. 537-546
-
-
Kopf, P.G.1
Scott, J.A.2
Agbor, L.N.3
Boberg, J.R.4
Elased, K.M.5
Huwe, J.K.6
-
20
-
-
0028865229
-
Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture
-
Langouet, S., Coles, B., Morel, F., Becquemont, L., Beaune, P., Guengerich, F. P., et al. (1995). Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture. Cancer Res. 55, 5574-5579.
-
(1995)
Cancer Res
, vol.55
, pp. 5574-5579
-
-
Langouet, S.1
Coles, B.2
Morel, F.3
Becquemont, L.4
Beaune, P.5
Guengerich, F.P.6
-
21
-
-
79551588087
-
CYP-mediated therapeutic protein-drug interactions: clinical findings, proposed mechanisms and regulatory implications
-
Lee, J. I., Zhang, L., Men, A. Y., Kenna, L. A., and Huang, S. M. (2010). CYP-mediated therapeutic protein-drug interactions: clinical findings, proposed mechanisms and regulatory implications. Clin. Pharmacokinet. 49,295-310.
-
(2010)
Clin. Pharmacokinet.
, vol.49
, pp. 295-310
-
-
Lee, J.I.1
Zhang, L.2
Men, A.Y.3
Kenna, L.A.4
Huang, S.M.5
-
22
-
-
0028906113
-
Evidence for the ligand-independent activation of the AH receptor
-
Lesca, P., Peryt, B., Larrieu, G., Alvinerie, M., Galtier, P., Daujat, M., et al. (1995). Evidence for the ligand-independent activation of the AH receptor. Biochem. Biophys. Res. Commun. 209, 474-482.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.209
, pp. 474-482
-
-
Lesca, P.1
Peryt, B.2
Larrieu, G.3
Alvinerie, M.4
Galtier, P.5
Daujat, M.6
-
23
-
-
0035032568
-
Interindividual variability in inhibition and induction of cytochrome P450 enzymes
-
Lin, J. H., and Lu, A. Y. (2001). Interindividual variability in inhibition and induction of cytochrome P450 enzymes. Annu. Rev. Pharmacol. Toxicol. 41, 535-567.
-
(2001)
Annu. Rev. Pharmacol. Toxicol.
, vol.41
, pp. 535-567
-
-
Lin, J.H.1
Lu, A.Y.2
-
24
-
-
34250708477
-
CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies
-
Ma, Q., and Lu, A. Y. (2007). CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies. Drug Metab. Dispos. 35, 1009-1016.
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 1009-1016
-
-
Ma, Q.1
Lu, A.Y.2
-
25
-
-
1842480976
-
Regulation of NAD(P)H:quinone oxidore-ductase 1 gene expression by CYP1A1 activity
-
Marchand, A., Barouki, R., and Garlatti, M. (2004). Regulation of NAD(P)H:quinone oxidore-ductase 1 gene expression by CYP1A1 activity. Mol. Pharmacol. 65, 1029-1037.
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 1029-1037
-
-
Marchand, A.1
Barouki, R.2
Garlatti, M.3
-
26
-
-
60649095638
-
Timing is everything: consequences of transient and sustained AhR activity
-
Mitchell, K. A., and Elferink, C. J. (2009). Timing is everything: consequences of transient and sustained AhR activity. Biochem. Pharmacol. 77, 947-956.
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 947-956
-
-
Mitchell, K.A.1
Elferink, C.J.2
-
27
-
-
0032875364
-
An autoregulatory loop controlling CYP1A1 gene expression: role of H(2)O(2) and NFI
-
Morel, Y., Mermod, N., and Barouki, R. (1999). An autoregulatory loop controlling CYP1A1 gene expression: role of H(2)O(2) and NFI. Mol. Cell. Biol. 19, 6825-6832.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6825-6832
-
-
Morel, Y.1
Mermod, N.2
Barouki, R.3
-
28
-
-
33845267470
-
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
-
Nebert, D. W., and Dalton, T. P. (2006). The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis. Nat. Rev. Cancer 6, 947-960.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 947-960
-
-
Nebert, D.W.1
Dalton, T.P.2
-
29
-
-
2642510760
-
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxic-ity and cancer
-
Nebert, D. W., Dalton, T. P., Okey, A. B., and Gonzalez, F. J. (2004). Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxic-ity and cancer. J. Biol. Chem. 279, 23847-23850.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23847-23850
-
-
Nebert, D.W.1
Dalton, T.P.2
Okey, A.B.3
Gonzalez, F.J.4
-
30
-
-
38949097735
-
The search for endogenous activators of the aryl hydrocarbon receptor
-
Nguyen, L. P., and Bradfield, C. A. (2008). The search for endogenous activators of the aryl hydrocarbon receptor. Chem. Res. Toxicol. 21, 102-116.
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 102-116
-
-
Nguyen, L.P.1
Bradfield, C.A.2
-
31
-
-
33645554647
-
Primary structure and organ-specific expression of the rat aryl hydrocarbon receptor repres-sor gene
-
Nishihashi, H., Kanno, Y., Tomuro, K., Nakahama, T., and Inouye, Y. (2006). Primary structure and organ-specific expression of the rat aryl hydrocarbon receptor repres-sor gene. Biol. Pharm. Bull. 29, 640-647.
-
(2006)
Biol. Pharm. Bull.
, vol.29
, pp. 640-647
-
-
Nishihashi, H.1
Kanno, Y.2
Tomuro, K.3
Nakahama, T.4
Inouye, Y.5
-
32
-
-
0034897230
-
Activation of the Ah receptor signaling pathway by prostaglandins
-
Seidel, S. D., Winters, G. M., Rogers, W. J., Ziccardi, M. H., Li, V., Keser, B., et al. (2001). Activation of the Ah receptor signaling pathway by prostaglandins. J. Biochem. Mol. Toxicol. 15, 187-196.
-
(2001)
J. Biochem. Mol. Toxicol.
, vol.15
, pp. 187-196
-
-
Seidel, S.D.1
Winters, G.M.2
Rogers, W.J.3
Ziccardi, M.H.4
Li, V.5
Keser, B.6
-
33
-
-
0035011152
-
In vivo inhibition of human CYP1A2 activity by oltipraz
-
Sofowora, G. G., Choo, E. F., Mayo, G., Shyr, Y., and Wilkinson, G. R. (2001). In vivo inhibition of human CYP1A2 activity by oltipraz. Cancer Chemother. Pharmacol. 47, 505-510.
-
(2001)
Cancer Chemother. Pharmacol.
, vol.47
, pp. 505-510
-
-
Sofowora, G.G.1
Choo, E.F.2
Mayo, G.3
Shyr, Y.4
Wilkinson, G.R.5
-
34
-
-
0035977845
-
Microarray analysis of hep-atotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity
-
Waring, J. F., Ciurlionis, R., Jolly, R. A., Heindel, M., and Ulrich, R. G. (2001). Microarray analysis of hep-atotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. Toxicol. Lett. 120, 359-368.
-
(2001)
Toxicol. Lett.
, vol.120
, pp. 359-368
-
-
Waring, J.F.1
Ciurlionis, R.2
Jolly, R.A.3
Heindel, M.4
Ulrich, R.G.5
-
35
-
-
77949888715
-
On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations
-
Zhu, B. T. (2010). On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations. Expert Opin. Drug Metab. Toxicol. 6, 483-494.
-
(2010)
Expert Opin. Drug Metab. Toxicol.
, vol.6
, pp. 483-494
-
-
Zhu, B.T.1
|