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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 9, 2013, Pages 2636-2641

Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease

(4) Li, Ren Shi a Wang, Xiao Bing a Hu, Xiao Jun a Kong, Ling Yi a

a CHINA PHARMACEUTICAL UNIVERSITY (China)

Author keywords

Acetylcholinesterase inhibitors; Anti amyloid aggregation; Biometal chelating agents; Flavonoid derivatives; Molecular modeling

Indexed keywords

AMYLOID BETA PROTEIN; CHELATING AGENT; CHOLINESTERASE INHIBITOR; FLAVONOID; GALANTAMINE; TACRINE;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; MOLECULAR MODEL; PROTEIN AGGREGATION;

ACETYLCHOLINESTERASE; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BINDING SITES; CATALYTIC DOMAIN; CHOLINESTERASE INHIBITORS; DRUG DESIGN; FLAVONOIDS; HUMANS; KINETICS; MOLECULAR DOCKING SIMULATION; PEPTIDE FRAGMENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84876120908 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.02.095 Document Type: Article

Times cited : (94)

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