Poorer physical fitness is associated with reduced structural brain integrity in heart failure

Journal of the Neurological Sciences

Volumn 328, Issue 1-2, 2013, Pages 51-57

  Alosco, Michael L ^a   Brickman, Adam M ^b   Spitznagel, Mary Beth ^a,c   Griffith, Erica Y ^b   Narkhede, Atul ^b   Raz, Naftali ^d   Cohen, Ronald ^e,f   Sweet, Lawrence H ^g   Colbert, Lisa H ^h   Josephson, Richard ^i,j,k   Hughes, Joel ^a,c   Rosneck, Jim ^c   Gunstad, John ^a,c  

^a KENT STATE UNIVERSITY   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c AKRON CITY HOSPITAL   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

^f UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF GEORGIA   (United States)

^h UNIVERSITY OF WISCONSIN MADISON   (United States)

ⁱ UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^j Harrington Heart and Vascular Institute   (United States)

^k CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Brain; Cognitive function; Heart failure; Neuroimaging; Physical fitness

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN; BRAIN CORTEX; BRAIN SIZE; COGNITION; CORTICAL THICKNESS (BRAIN); DEMOGRAPHY; FEMALE; FITNESS; FOLLOW UP; GRAY MATTER; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCIPITAL LOBE; PREDICTIVE VALIDITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; WHITE MATTER;

AGED; AGED, 80 AND OVER; BRAIN; COGNITION DISORDERS; DEPRESSION; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MENTAL STATUS SCHEDULE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PHYSICAL FITNESS; REGRESSION ANALYSIS;

EID: 84876109745     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2013.02.015     Document Type: Article

References (76)

1. V.L. Roger, A.S. Go, D.M. Lloyd-Jones, E.J. Benjamin, J.D. Berry, and W.B. Borden Heart disease and stroke statistics - 2012 update Circulation 125 2012 e2 e220
2. D. Lloyd-Jones, R. Adams, M. Carnethon, G. De Simon, T.B. Gerguson, and K. Flegal Heart disease and stroke statistics - 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation 119 2009 e21 e181
3. P.A. Heidenreich, J.G. Trogdon, O.A. Khavjou, J. Butler, K. Dracup, and M.D. Ezekowitz Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association Circulation 123 2011 933 944
4. S.F. Jencks, M.V. Williams, and E.A. Coleman Rehospitalization among patients in Medicare fee-for-service program N Engl J Med 360 2009 1418 1428
5. S.J. Bennett, N.B. Oldridge, G. Eckert, J.L. Embree, S. Browing, and N. Hou Comparison of quality of life measures in heart failure Nurs Res 52 2003 207 216
6. B. Riegel, and T.E. Weaver Poor sleep and impaired self-care: towards a comprehensive model linking sleep, cognition, and heart failure outcomes Eur J Cardiovasc Nurs 2009 337 344
7. S.J. Pressler, U. Subramanian, D. Kareken, S.M. Perksin, I. Gradus-Pizlo, and M.J. Suave Cognitive deficits in chronic heart failure Nurs Res 59 2010 127 139
8. C. Qiu, B. Winblad, A. Marengoni, I. Klarin, J. Fastbom, and L. Fratiglioni Heart failure and risk of dementia and Alzheimer disease: a population-based cohort study Arch Intern Med 166 2006 1003 1008
9. G. Roman Vascular dementia prevention: a risk factor analysis Cerebrovasc Dis 20 2005 91 100 (Pubitemid 44689464)
10. M.J. Suave, W.R. Lewis, M. Blankenbiller, B. Rickabuagh, and S.J. Pressler Cognitive impairments in chronic heart failure: a case controlled study J Card Fail 15 2009 1 10
11. R.L.C. Vogels, P. Scheltens, J.M. Schroeder-Tanka, and H.C. Weinstein Cognitive impairment in heart failure: a systematic review of the literature Eur J Heart Fail 9 2007 440 449 (Pubitemid 46561483)
12. R.L. Vogels, W.M. van der flier, B. van Harten, A.A. Gouw, P. Scheltens, and J.M. Schroeder-Tanka Brain magnetic resonance imaging abnormalities in patients with heart failure Eur J Heart Fail 9 2007 1003 1009 (Pubitemid 47451813)
13. M. Woo, P. Macey, G.C. Fonarow, M.A. Hamilton, and R.M. Harper Regional brain gray matter loss in heart failure J Appl Physiol 95 2003 677 684 (Pubitemid 36944291)
14. M.A. Woo, R. Kumar, P.M. Macey, G.C. Fonarow, and R.M. Harper Brain injury in autonomic, emotional, and cognitive regulatory areas in patients with heart failure J Card Fail 15 2009 214 223
15. R. Kumar, M.A. Woo, P.M. Macey, G.C. Fonarow, M.A. Hamilton, and R.M. Harper Brain axonal and myelin evaluation in heart failure J Neurol Sci 307 2011 106 113
16. R.L. Vogels, J.M. Oosterman, B. van Harten, A.A. Gouw, J.M. Schroeder-Tanka, and P. Scheltens Neuroimaging and correlates of cognitive function among patients with heart failure Dement Geriatr Cogn Disord 24 2007 418 423 (Pubitemid 350175900)
17. J.R. Almeida, T.C. Alves, M. Wajngarten, J. Rays, C.C. Castro, and Q. Cordeiro Late-life depression, heart failure and frontal white matter hyperintensity: a structural magnetic resonance imaging study Braz J Med Biol Res 38 2005 431 436 (Pubitemid 40485183)
18. S.L. Serber, Kumar, M.A. Woo, P.M. Macey, G.C. Fonarow, and R.M. Harper Cognitive test performance and brain pathology Nurs Res 57 2008 75 83
19. P. Bhattacharya, F. Bao, M. Shah, G. Ramesh, R. Madhavan, and O. Khan Left ventricular dysfunction is associated with cerebral grey matter injury: an in-vivo brain MRI segmentation study J Neurol Sci 321 2012 111 113 [epub ahead of print]
20. T.C. Alves, J. Rays, R. Fraguas Jr., M. Wajngarten, J.C. Meneghetti, and S. Prando Localized cerebral blood fl ow reductions in patients with heart failure: a study using 99mTc-HMPAO SPECT J Neuroimaging 15 2005 150 156 (Pubitemid 40388319)
21. R.L. Vogels, J.M. Oosterman, D.M. Laman, A.A. Gouw, J.M. Schroeder-Tanka, and P. Scheltens Transcranial Doppler blood flow assessment in patients with mild heart failure: correlates with neuroimaging and cognitive performance Congest Heart Fail 14 2008 61 65
22. I.L. Pina, C.S. Apstein, G.J. Balady, R. Belardinelli, B.R. Chaitman, and B.D. Duscha AHA scientific statement. Exercise and heart failure. A statement from the American Heart Association Committee on Exercise, Rehabilitation, and Prevention Circulation 107 2003 1210 1225 (Pubitemid 36297217)
23. C. Lucas, L.W. Stevenson, W. Johnson, H. Hartley, M.A. Hamilton, and J. Walden The 6-min walk and peak oxygen consumption in advanced heart failure: aerobic capacity and survival Am Heart J 138 1999 618 624 (Pubitemid 29471034)
24. R. Boxer, A. Klepppinger, A. Ahmad, K. Annis, D. Hager, and A. Kenny The 6-minute walk is associated with frailty and predicts mortality in older adults with heart failure Congest Heart Fail 16 2010 208 213
25. A.M. Swank, J. Horton, J.L. Fleg, G.C. Fonarow, S. Keteyian, and L. Goldberg Modest increase in peak VO2 is related to better clinical outcomes in chronic heart failure patients: results from Heart Failure and a Controlled Trial to Investigate Outcomes of Exercise Training (HF-ACTION) Circ Heart Fail 5 2012 579 585 [epub ahead of print]
26. J.R. Dutcher, J. Kahn, C. Grines, and B. Franklin Comparison of left ventricular ejection fraction and exercise capacity as predictors of two- and five-year mortality following acute myocardial infarction Am J Cardiol 99 2007 436 441 (Pubitemid 46215542)
27. M.L. Alosco, M.B. Spitznagel, N. Raz, R. Cohen, L.H. Sweet, and L.H. Colbert The 2-minute step test is independently associated with cognitive function in older adults with heart failure Aging Clin Exp Res 24 2012 468 474 [epub ahead of print]
28. G. Steinberg, N. Lossnitzer, D. Schellberg, T. Mueller-Tasch, C. Krueger, and M. Haas Peak oxygen uptake and left ventricular ejection fraction, but not depressive symptoms, are associated with cognitive impairment in patients with heart failure Int J Gen Med 4 2011 879 887
29. S. Baldasseroni, E. Mossello, B. Romboli, F. Orso, C. Colombi, and S. Fumagalli Relationship between cognitive function and 6-minute walking test in older outpatients with chronic heart failure Aging Clin Exp Res 22 2010 308 313
30. N. Raz, F.M. Dixon, D.P. Head, J.H. Dupuis, and J.D. Acker Neuroanatomical correlates of cognitive aging: evidence from structural MRI Neuropsychology 12 1998 95 106
31. N. Raz, K.M. Rodrigue, and J.D. Acker Hypertension and the brain: vulnerability of the prefrontal regions and executive functions Behav Neurosci 17 2003 1169 1180 (Pubitemid 37549420)
32. S.J. Colcombe, K.I. Erickson, N. Raz, A.H. Webb, N.J. Cohen, and E. McAuley Aerobic fitness reduces brain tissue loss in aging humans J Gerontol A Biol Sci Med Sci 53 2003 176 180 (Pubitemid 36222821)
33. K.I. Erickson, R.S. Prakash, M.W. Voss, L. Chaddock, L. Hu, and K.S. Morris Aerobic fitness is associated with hippocampal volume in elderly humans Hippocampus 19 2009 1030 1039
34. J.M. Burns, B.B. Cronk, H.S. Anderson, J.E. Donnelly, G.P. Thomas, and A. Harsha Cardiorespiratory fitness and brain atrophy in early Alzheimer's disease Neurology 71 2008 210 216
35. C.M. O'Connor, D.J. Whellan, K.L. Lee, S.J. Keteyian, L.S. Cooper, and S.J. Ellis Efficacy and safety of exercise training in patients with chronic heart failure. HF-ACTION randomized controlled trial JAMA 301 2009 1439 1450
36. S.W. Seo, J.W. Lee, K. Im, J.S. Park, S.H. Kim, and S.T. Kim Cardiovascular risk factors cause cortical thinning in cognitively impaired patients: relationships among cardiovascular risk factors, white matter hyperintensities, and cortical atrophy Alzheimer Dis Assoc Disord 26 2012 106 112
37. C.A. Raji, O.L. Lopez, L.H. Kuller, O.T. Carmichael, W.T. Longstreth, and H.M. Gach White matter lesions and brain gray matter volume in cognitive normal elders Neurobiol Aging 33 2012 e7 e16
38. B. Fischl, and A.M. Dale Measuring the thickness of the human cerebral cortex from magnetic resonance images Proc Natl Acad Sci U S A 97 2000 11050 11055
39. B. Fischl, D.H. Salat, E. Busa, M. Albert, M. Dieterich, and C. Haseigrove Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain Neuron 33 2002 341 355 (Pubitemid 34162530)
40. B. Fischl, M.I. Sereno, and A.M. Dale Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system Neuroimage 9 1999 195 207 (Pubitemid 29369875)
41. B. Fischl, A. van der Kouwe, C. Destrieux, E. Haigren, F. Segonne, and D.H. Salat Automatically parcellating the human cerebral cortex Cereb Cortex 14 2004 11 22 (Pubitemid 38018050)
42. R.S. Desikan, F. Segonne, B. Fischl, B.T. Quinn, B.C. Dickerson, and D. Blacker An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest Neuroimage 31 2006 968 980 (Pubitemid 44183792)
43. C.J. Jones, and R.E. Rikli Measuring functional fitness of older adults J Act Aging March April 2002 24 30
44. E. Teng, and H. Chui The Modified Mini-Mental (3MS) examination J Clin Psychiatry 48 1987 314 318
45. R.C. Bland, and S.C. Newman Mild dementia or cognitive impairment: the Modified Mini-Mental State examination (3MS) as a screen for dementia Can J Psychiatry 46 2001 506 510 (Pubitemid 32861417)
46. R. Arnau, M. Meagher, M. Norris, and R. Bramson Psychometric evaluation of the Beck Depression Inventory-II with primary care medical patients Health Psychol 20 2001 112 119 (Pubitemid 32233867)
47. A.T. Beck, R.A. Steer, and G.K. Brown Beck Depression Inventory 2nd ed. 1996 The Psychological Corporation San Antonio, TX
48. A.N. Szabo, E. McAuley, K.I. Erickson, M. Voss, R.S. Prakash, and E.L. Mailey Cardiorespiratory fitness, hippocampal volume, and frequency of forgetting in older adults Neuropsychology 25 2011 545 553
49. E. McAuley, A.F. Kramer, and S.J. Colcombe Cardiovascular fitness and neurocognitive function in older adults: a brief review Brain Behav Immun 18 2004 214 220 (Pubitemid 38429761)
50. J. Peters, M. Dauvermann, C. Mette, P. Platen, J. Franke, and T. Hinrichs Voxel-based morphmoetry reveals and association between aeropic capacity and grey matter density in the right anterior insula Neuroscience 163 2009 1102 1108
51. E.D. Vidon, R.A. Honea, S.A. Billinger, R.H. Swerdlow, and J.M. Burns Cardiorepiratory fitness is associated with atrophy in Alzheimer's and aging over 2 years Neurobiol Aging 33 2012 1624 16632
52. H. van Praag, T. Shubert, C. Zhao, and F.H. Gage Exercise enhances learning and hippocampal neurogenesis in aged mice J Neurosci 25 2005 8680 8868
53. B.R. Christie, B.D. Eadie, T.S. Kannangara, J.M. Robillard, J. Shin, and A.K. Titterness Exercising our brains: how physical activity impacts synaptic plasticity in the dentate gyrus Neuromolecular Med 10 2008 47 58
54. G.S. Griesbach, F. Gomez-Pinilla, and D.A. Hovda Time window for voluntary exercise-induced increases in hippocampal neuroplasticity molecules after traumatic brain injury is severity dependent J Neurotrauma 24 2007 1161 1171 (Pubitemid 47106289)
55. T.C. Fu, C.H. Wang, P.S. Lin, C.C. Hsu, W.J. Cherng, and S.C. Huang Aerobic interval training improves oxygen uptake efficiency by enhancing cerebral and muscular hemodynamics in patients with heart failure Int J Cardiol 2011 [epub ahead of print]
56. T.C. Fu, C.H. Wang, C.C. Hsu, W.J. Cherng, S.C. Huang, and J.S. Wang Suprression of cerebral hemodynamics is associated with reduced functional capacity in patients with heart failure Am J Physiol Heart Circ Physiol 300 2011 H1545 H1555
57. T. Corvera-Tindel, L. Doering, M.A. Woo, S. Khan, and K. Dracup Effects of a home-walking exercise program on functional status and symptoms in heart failure Am Heart J 147 2004 339 346 (Pubitemid 38176836)
58. A.J. Chicco Exercise training in prevention and rehabilitation which training mode is best? Minerva Cardioangiol 56 2008 557 570
59. G. Papathanasiou, N. Tsamis, P. Georgiadou, and S. Adamopoulos Beneficial effects of physical training and methodology of exercise prescription in patients with heart failure Hellenic J Cardiol 49 2008 267 277
60. K. Davison, S. Bircher, A. Hill, A.M. Coates, P.R. Howe, and J.D. Buckley Relationships between obesity, cardiorespiratory fitness, and cardiovascular function J Obes 2010 191253
61. D.J. Moser, K.F. Hoth, R.G. Robinson, J.S. Paulsen, C.A. Sinkey, and M.L. Benjamin Blood vessel function and cognition in elderly patients with atherosclerosis Stroke 35 2004 e369 e372
62. A. Jefferson, A. Poppas, R. Paul, and R.A. Cohen Systemic hypoperfusion is associated with executive dysfunction in geriatric cardiac patients Neurobiol Aging 28 2007 477 483 (Pubitemid 46178529)
63. A.L. Jefferson, D.F. Tate, A. Poppas, A.M. Brickman, R.H. Paul, and J. Gunstad Lower cardiac output is associated with greater white matter hyperintensities in older adults with cardiovascular disease J Am Geriatr Soc 55 2007 1044 1048 (Pubitemid 47024621)
64. C.E. Hugenschmidt, A.M. Peiffer, R.A. Kraft, R. Casanova, A.R. Deibler, and J.H. Burdette Relating imaging indices of white matter integrity and volume in healthy older adults Cereb Cortex 18 2008 433 442 (Pubitemid 351197803)
65. A.C. Pereira, D.R. Huddleston, A.M. Brickman, A.A. Sosunov, R. Hen, and G.M. McKhann An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus Proc Natl Acad Sci U S A 104 2007 5638 5643 (Pubitemid 47175733)
66. A.M. Fjell, L.T. Westlye, I. Amlien, T. Espeseth, I. Reinvang, and N. Raz High consistency of regional cortical thinning in aging across multiple samples Cereb Cortex 19 2009 2001 2012
67. N. Raz, U. Lindenberger, K.M. Rodrigue, K.M. Kennedy, D. Head, and A. Williamson Regional brain changes in aging healthy adults: general trends, individual differences, and modifiers Cereb Cortex 15 2005 1676 1689 (Pubitemid 41447032)
68. N. Raz, K.M. Rodrigue, K.M. Kennedy, and J.D. Acker Vascular health and longitudinal changes in brain and cognition in middle-aged and older adults Neuropsychology 21 2007 149 157 (Pubitemid 46631097)
69. K.M. Stanek, J. Gunstad, M.B. Spitznagel, D. Waechter, J.W. Hughes, and F. Luyster Improvements in cognitive function following cardiac rehabilitation for older adults with cardiovascular disease Int J Neurosci 121 2011 86 93
70. M.L. Alosco, M.B. Spitznagel, M. van Dulmen, N. Raz, R. Cohen, and L.H. Sweet Cognitive function and treatment adherence in older adults with heart failure Psychosom Med 74 2012 965 973
71. G. Zuccala, C. Pedone, M. Cesari, G. Onder, M. Pahor, and E. Marzetti The effects of cognitive impairment on mortality among hospitalized patients with heart failure Am J Med 115 2003 97 103 (Pubitemid 37288836)
72. A.L. Jefferson, J.J. Himali, R. Au, S. Seshadri, C. Decarli, and C.J. O'Donnell Relation of left ventricular ejection fraction to cognitive aging (from the Framingham Heart Study) Am J Cardiol 108 2011 1346 1351
73. R.L. Vogels, J.M. Oosterman, D.M. Laman, A.A. Gouw, J.M. Schroeder-Tanka, and P. Scheltens Transcranial Doppler blood flow assessment in patients with mild heart failure: correlates with neuroimaging and cognitive performance Congest Heart Fail 14 2008 61 65
74. K.I. Eickson, C.A. Raji, O.L. Lopez, J.T. Becker, C. Rosano, and A.B. Newman Physical activity predicts gray matter volume in late adulthood: the Cardiovascular Health Study Neurology 75 2010 1415 1422
75. K.I. Erickson, M.W. Voss, R.S. Prakash, C. Basak, A. Szabo, and L. Chaddock Exercise training increases size of hippocampus and improves memory Proc Natl Acad Sci U S A 108 2011 3017 3022
76. J.M. Bugg, and D. Head Exercise moderates age-related atrophy of the medial temporal lobe Neurobiol Aging 32 2011 506 514