Expression of R132H mutational IDH1 in human U87 glioblastoma cells affects the SREBP1a pathway and induces cellular proliferation

Journal of Molecular Neuroscience

Volumn 50, Issue 1, 2013, Pages 165-171

  Zhu, Jian ^a   Cui, Gang ^b   Chen, Ming ^c   Xu, Qinian ^b   Wang, Xiuyun ^b   Zhou, Dai ^b   Lv, Shengxiang ^d   Fu, Linshan ^a   Wang, Zhong ^b   Zuo, Jianling ^b  

^a NANTONG UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c The First Hospital of Changzhou   (China)

^d Department of Gastroenterology   (China)

Author keywords

Glioma; Isocitrate dehydrogenase 1 (IDH1); Proliferation; Sterol regulatory element binding protein (SREBP)

Indexed keywords

EDOXUDINE; ISOCITRATE DEHYDROGENASE 1; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; SULFORHODAMINE B;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; GENETIC TRANSFECTION; GLIOBLASTOMA; GLIOMA CELL; HEALING; HUMAN; HUMAN CELL; HUMAN TISSUE; MIGRATION; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; WESTERN BLOTTING;

CELL ENLARGEMENT; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GLIOBLASTOMA; HUMANS; ISOCITRATE DEHYDROGENASE; MUTATION, MISSENSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84876108430     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9890-6     Document Type: Article

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