Dexamethasone administration to the neonatal rat results in neurological dysfunction at the juvenile stage even at low doses

Early Human Development

Volumn 89, Issue 5, 2013, Pages 283-288

  Ichinohashi, Yuko ^a,b   Sato, Yoshiaki ^b   Saito, Akiko ^b   Ito, Miharu ^b   Watanabe, Kimi ^b   Hayakawa, Masahiro ^b   Nakanishi, Keiko ^d   Wakatsuki, Akihiko ^a   Oohira, Atsuhiko ^b,c  

^a AICHI MEDICAL UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY HOSPITAL   (Japan)

^c AICHI MEDICAL UNIVERSITY   (Japan)

^d INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

Author keywords

Cell proliferation; Dexamethasone; Glucocorticoid; Neural stem progenitor cells; Neurologic dysfunction; Premature brain

Indexed keywords

DEXAMETHASONE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN WEIGHT; CELL COUNT; CELL DEATH; CELL DENSITY; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG EXPOSURE; GESTATIONAL AGE; GROWTH RETARDATION; HIPPOCAMPUS; HISTOPATHOLOGY; JUVENILE; LEARNING DISORDER; LOW DRUG DOSE; MITOSIS; NERVE CELL CULTURE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROLOGIC DISEASE; NEWBORN; NONHUMAN; OPEN FIELD TEST; PERINATAL PERIOD; PREMATURITY; RAT; REARING; TREATMENT DURATION;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; AVOIDANCE LEARNING; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; NERVOUS SYSTEM DISEASES; NEURAL STEM CELLS; ORGAN SIZE; RATS; VIDEO RECORDING;

EID: 84876101582     PISSN: 03783782     EISSN: 18726232     Source Type: Journal    
DOI: 10.1016/j.earlhumdev.2012.10.007     Document Type: Article

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