CEACAM1 regulates Fas-mediated apoptosis in Jurkat T-cells via its interaction with Β-catenin

Experimental Cell Research

Volumn 319, Issue 8, 2013, Pages 1061-1072

  Li, Yun ^a   Shively, John E ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Actin cytoskeleton; Apoptosis; CEACAM1: carcinoembryonic antigen related cell adhesion molecule 1; Fas; Jurkat cell; T cell; Catenin

Indexed keywords

ASPARTIC ACID; BETA CATENIN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; FAS ANTIGEN;

ACTIN FILAMENT; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; WESTERN BLOTTING;

ARMADILLO;

EID: 84876095230     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.02.020     Document Type: Article

References (26)

1. Chen C.J., Kirshner J., Sherman M.A., Hu W., Nguyen T., Shively J.E. Mutation analysis of the short cytoplasmic domain of the cell-cell adhesion molecule CEACAM1 identifies residues that orchestrate actin binding and lumen formation. J. Biol. Chem. 2007, 282:5749-5760.
2. Gray-Owen S.D., Blumberg R.S. CEACAM1: contact-dependent control of immunity. Nat. Rev. Immunol. 2006, 6:433-446.
3. Chen C.J., Shively J.E. The cell-cell adhesion molecule carcinoembryonic antigen-related cellular adhesion molecule 1 inhibits IL-2 production and proliferation in human T cells by association with Src homology protein-1 and down-regulates IL-2 receptor. J. Immunol. 2004, 172:3544-3552.
4. Chen Z., Chen L., Qiao S.W., Nagaishi T., Blumberg R.S. Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70. J. Immunol. 2008, 180:6085-6093.
5. Jin L., Li Y., Chen C.J., Sherman M.A., Le K., Shively J.E. Direct interaction of tumor suppressor CEACAM1 with beta catenin: identification of key residues in the long cytoplasmic domain. Exp. Biol. Med. 2008, 233:849-859.
6. Luis T.C., Ichii M., Brugman M.H., Kincade P., Staal F.J. Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development. Leukemia 2012, 26:414-421.
7. Gattinoni L., Ji Y., Restifo N.P. Wnt/beta-catenin signaling in T-cell immunity and cancer immunotherapy. Clin. Cancer Res.: Off. J. Am. Assoc. Cancer Res. 2010, 16:4695-4701.
8. Varas A., Hager-Theodorides A.L., Sacedon R., Vicente A., Zapata A.G., Crompton T. The role of morphogens in T-cell development. Trends Immunol. 2003, 24:197-206.
9. Ge X., Wang X. Role of Wnt canonical pathway in hematological malignancies. J. Hematol. Oncol. 2010, 3:33.
10. Chung E.J., Hwang S.G., Nguyen P., Lee S., Kim J.S., Kim J.W., Henkart P.A., Bottaro D.P., Soon L., Bonvini P., Lee S.J., Karp J.E., Oh H.J., Rubin J.S., Trepel J.B. Regulation of leukemic cell adhesion, proliferation, and survival by beta-catenin. Blood 2002, 100:982-990.
11. Nagata S. Apoptosis by death factor. Cell 1997, 88:355-365.
12. Lobo E.O., Zhang Z., Shively J.E. Pivotal advance: CEACAM1 is a negative coreceptor for the B cell receptor and promotes CD19-mediated adhesion of B cells in a PI3K-dependent manner. J. Leukocyte Biol. 2009, 86:205-218.
13. Yu Q., Chow E.M., Wong H., Gu J., Mandelboim O., Gray-Owen S.D., Ostrowski M.A. CEACAM1 (CD66a) promotes human monocyte survival via a phosphatidylinositol 3-kinase- and AKT-dependent pathway. J. Biol. Chem. 2006, 281:39179-39193.
14. Lasa A., Serrano E., Carricondo M., Carnicer M.J., Brunet S., Badell I., Sierra J., Aventin A., Nomdedeu J.F. High expression of CEACAM6 and CEACAM8 mRNA in acute lymphoblastic leukemias. Ann. Hematol. 2008, 87:205-211.
15. Hwang S.G., Lee H.C., Trepel J.B., Jeon B.H. Anticancer-drug-induced apoptotic cell death in leukemia cells is associated with proteolysis of beta-catenin. Leuk. Res. 2002, 26:863-871.
16. Sadekova S., Lamarche-Vane N., Li X., Beauchemin N. The CEACAM1-L glycoprotein associates with the actin cytoskeleton and localizes to cell-cell contact through activation of Rho-like GTPases. Mol. Biol. Cell 2000, 11:65-77.
17. Huang Z., Wang R., Xie H., Shang W., Manicassamy S., Sun Z. Stabilized beta-catenin potentiates Fas-mediated T-cell apoptosis. J. Immunol. 2008, 180:6586-6592.
18. Chen C.J., Nguyen T., Shively J.E. Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells. Exp. Cell Res. 2010, 316:638-648.
19. An W.G., Hwang S.G., Trepel J.B., Blagosklonny M.V. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia 2000, 14:1276-1283.
20. Johnson N., Ng T.T., Parkin J.M. Camptothecin causes cell cycle perturbations within T-lymphoblastoid cells followed by dose dependent induction of apoptosis. Leuk. Res. 1997, 21:961-972.
21. Krueger A., Fas S.C., Baumann S., Krammer P.H. The role of CD95 in the regulation of peripheral T-cell apoptosis. Immunol. Rev. 2003, 193:58-69.
22. Bonvini P., An W.G., Rosolen A., Nguyen P., Trepel J., Garcia de Herreros A., Dunach M., Neckers L.M. Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription. Cancer Res. 2001, 61:1671-1677.
23. Najjar S.M. Regulation of insulin action by CEACAM1. Trends Endocrinol. Metab. 2002, TEM13:240-245.
24. Abou-Rjaily G.A., Lee S.J., May D., Al-Share Q.Y., Deangelis A.M., Ruch R.J., Neumaier M., Kalthoff H., Lin S.H., Najjar S.M. CEACAM1 modulates epidermal growth factor receptor-mediated cell proliferation. J. Clin. Invest. 2004, 114:944-952.
25. Bullions L.C., Levine A.J. The role of beta-catenin in cell adhesion, signal transduction, and cancer. Curr. Opinion Oncol. 1998, 10:81-87.
26. Xie H., Huang Z., Sadim M.S., Sun Z. Stabilized beta-catenin extends thymocyte survival by up-regulating Bcl-xL. J. Immunol. 2005, 175:7981-7988.